Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=3613c363-bf7a-4dac-9cca-d6e1829f7a4e&Preview=1 Date 11/17/2011 Company Name Allena Pharmaceuticals Mailing Address One Newton Executive Park Newton, MA 02462 Company Description Allena Pharmaceuticals is developing and commercializing non-systemic protein therapeutics to treat metabolic and orphan diseases, with a particular focus on nephrologic and urologic conditions. Website http://www.allenapharma.com Transaction Type Venture Equity Transaction Amount $15,000,000 Transaction … Continue reading “Allena Pharmaceuticals Receives $15,000,000 Series A Round”
Category: Boston
Agios Pharmaceuticals Obtains $78,000,000 Series C Round
Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=f877cbf2-5e0b-42ec-9a73-e2410af734d1&Preview=1 Date 11/17/2011 Company Name Agios Pharmaceuticals Mailing Address 38 Sidney Street 2nd Floor Cambridge, MA 02139-4169 Company Description Agios is a biopharmaceutical company at the forefront of one of the most exciting new areas of cancer research: cancer metabolism. Cancer metabolism represents a breakthrough understanding of how cancer cells become addicted … Continue reading “Agios Pharmaceuticals Obtains $78,000,000 Series C Round”
Seniorlink Lands $5,000,000 New Funding
Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=9139295a-f736-450e-a3a1-bd49f9273f61&Preview=1 Date 11/17/2011 Company Name Seniorlink Mailing Address 500 Boylston Street Boston, MA 02116 Company Description Seniorlink is dedicated to helping frail seniors and people with disabilities live with dignity and independence. Website http://www.seniorlink.com Transaction Type Venture Equity Transaction Amount $5,000,000 Transaction Round Undisclosed Proceeds Purposes The new funding would be used … Continue reading “Seniorlink Lands $5,000,000 New Funding”
CounterTack Receives $9,500,000 Series A Financing
Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=17a552d3-a55d-4630-9e1b-c91ae4858585&Preview=1 Date 11/17/2011 Company Name CounterTack Mailing Address 303 Wyman Street Waltham, MA 02451 Company Description CounterTack, the industry’s first and only in-progress attack intelligence and response solution was born out of the critical need for enterprise and government organizations to approach security in a completely different way – combating advanced persistent … Continue reading “CounterTack Receives $9,500,000 Series A Financing”
Diary of a Leader: An Evening with Abbie Celniker
Eleven Biotherapeutics CEO Abbie Celniker will share insights on her career path at this evening event put on by the Healthcare Businesswomen’s Association Boston chapter. Attendees will also have the opportunity to ask questions. Sign up here.
2011 MIT Energy Finance Forum
Venture capitalist Ray Rothrock will kick off the MIT Energy Finance Forum. The rest of the day includes panels on energy topics such as nuclear, oil and gas, renewables, energy efficiency, and technology commercialization. Register here.
FirstFuel’s Analytics Software Looks to Help Utilities Better Spend the Billions Allocated for Energy Efficiency
“Utilities have a big problem,” says Swapnil Shah, CEO and co-founder of Waltham, MA-based FirstFuel Software. “They have a big pile of money they have to spend to achieve certain goals,” he continues. “If they don’t achieve it, they get penalized by the state.” The goal is to increase home and commercial energy efficiency so … Continue reading “FirstFuel’s Analytics Software Looks to Help Utilities Better Spend the Billions Allocated for Energy Efficiency”
Join Us for a Live “Tweetchat” on the Biotech VC Crisis with Daphne Zohar of PureTech Ventures
The biotech VC world is in crisis. Just in the space of a few weeks, some venerable names have made some disturbing news. Prospect Venture Partners said it was unable to raise a new fund, Morgenthaler Ventures and Advanced Technology Ventures said they are splitting off their life sciences teams to raise a new merged … Continue reading “Join Us for a Live “Tweetchat” on the Biotech VC Crisis with Daphne Zohar of PureTech Ventures”
Allena Pharma Launches With $15M From Third Rock and Other Top-Tier VCs
Allena Pharmaceuticals, based in Newton, MA, is announcing today that it has started up and raised $15 million in a Series A financing round, led by Third Rock Ventures, Frazier Healthcare, and Bessemer Venture Partners. The new company is pursuing protein therapeutics and is especially focused on kidney and urologic diseases. Its management team is … Continue reading “Allena Pharma Launches With $15M From Third Rock and Other Top-Tier VCs”
Shareholic Snaps Up Seed Money, Avaxia Inks $2.2M, RapidBuyr Buys BizDeals, & More Boston-Area Deals News
It’s been a quieter deals news week around New England, but Web software and drug developers have been reporting new financings and acquisitions. —Collabor, a Maynard, MA-based maker of collaboration software for businesses, is working on raising its first outside funding round from a group of area angel investors, according to CEO and founder Sandeep … Continue reading “Shareholic Snaps Up Seed Money, Avaxia Inks $2.2M, RapidBuyr Buys BizDeals, & More Boston-Area Deals News”
DrinksOnTap 11 – Pre-Holiday Edition
Mobile developers can network and show off their apps at this informal event. Sign up here to get into the mix.
2nd Annual Punchbowl Mixer
Punchbowl is putting its party planning skills to the test with this networking event for area Web entrepreneurs, venture capitalists, and marketers. RSVP here to make sure you get on the list.
Fenugreen and Dynamo Micropower Nab Top Spots at Kauffman’s Startup Open
Two Massachusetts companies, Fenugreen and Dynamo Micropower, took home the grand prizes this week at Startup Open, a competition put on by the Kauffman Foundation that recognizes startups with high-growth potential. Cambridge, MA-based Fenugreen develops all-natural food packaging material called FreshPaper that’s designed to give produce two to four times the shelf life it sees … Continue reading “Fenugreen and Dynamo Micropower Nab Top Spots at Kauffman’s Startup Open”
Acceleration 2011: Nutter Early Stage Life Sciences Conference
Speakers from Pfizer, Novartis, Atlas Venture, Longwood Founders Fund, SR One, Halloran Consulting Group, Concert Pharmaceuticals and more will assemble at this half-day life sciences conference. It’s targeted at med device, pharma, and biotech entrepreneurs, executives, and angel, seed, and venture capital investors. Register here.
Avaxia Pulls in $2M from Angels to Fund Development of Cow-Derived Drug
The phrase “pharmaceutical manufacturing” doesn’t generally evoke visions of dairy farms. But it does for Barbara Fox, co-founder and CEO of Lexington, MA-based Avaxia Biologics, which is developing a drug derived from cow’s milk. And she’s succeeding in getting investors to share her vision: On November 10, Avaxia announced that it had closed $2.2 million … Continue reading “Avaxia Pulls in $2M from Angels to Fund Development of Cow-Derived Drug”
Global Hawk Spy Plane Offers Glimpse of Future Robotics at Xconomy 6X6 Event on December 1
Think of it as a flying beluga whale. At least, that’s the way Xconomy’s San Diego editor Bruce Bigelow, once described the Global Hawk robot spy plane. And I have to say, I am personally very excited that this reconnaissance craft extraordinaire will be one of the featured presentations at our 6X6: Six Cities, Six … Continue reading “Global Hawk Spy Plane Offers Glimpse of Future Robotics at Xconomy 6X6 Event on December 1”
Reinventing the Board Part II: The Role of the Chair in Increasing Board Effectiveness
Technology companies’ boards of directors need better leadership. I made a case last month about reinventing the board of directors by treating the board as a team and doing annual assessments against company needs. Boards that are structurally more aligned with their company’s operations are better able to help them achieve success-or at least reduce … Continue reading “Reinventing the Board Part II: The Role of the Chair in Increasing Board Effectiveness”
Mnemosyne Pharmaceuticals Lands $250,000 Seed Financing Round
Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=c0ce2576-9291-4953-a4d8-60596d01fe6b&Preview=1 Date 11/15/2011 Company Name Mnemosyne Pharmaceuticals Mailing Address Undisclosed Providence, RI 02902 Company Description The company is a Providence-based drug discovery venture aiming to develop small molecule therapeutics to treat schizophrenia and other cognitive and neuropsychiatric disorders. Website Undisclosed Transaction Type Venture Equity Transaction Amount $250,000 Transaction Round Seed Proceeds Purposes … Continue reading “Mnemosyne Pharmaceuticals Lands $250,000 Seed Financing Round”
Genetics Institute Mementos: A Slide Show
Rummage through some of the memorabilia from Genetics Institute and a couple things become obvious right away. This was a company full of young, idealistic people that worked hard and knew how to have a good time. There’s the company softball jersey with “DNAces” stitched on the back. There’s a coffee mug that’s supposed to … Continue reading “Genetics Institute Mementos: A Slide Show”
AppBrick Is Out to Add Life To “Flat” E-Books with an Interactive Layer
Vijay Gaur sees the book going in the same direction that the mobile phone has. “We are converting a book into a platform,” says Gaur. “Your phone is becoming more powerful by applications. We are now applying that same concept to books.” That’s the idea behind his Medford, MA-based startup, AppBrick. The company, which graduated … Continue reading “AppBrick Is Out to Add Life To “Flat” E-Books with an Interactive Layer”
Hey, Where Is Everybody Going? The Flight from Healthcare Investing
If you are simply reading the paper or engaging in any random cocktail party conversation these days, it doesn’t take long before you are reading or talking about healthcare. Health and healthcare issues have been a dominant topic in the national media since the 2008 Presidential election and have been constantly in the news as … Continue reading “Hey, Where Is Everybody Going? The Flight from Healthcare Investing”
Genzyme MS Drug Significantly Reduces Relapse, Disability in Late-Stage Trial
Cambridge, MA-based Genzyme, owned by French drug giant Sanofi (NYSE: [[ticker:SNY]]) said today its experimental drug to treat multiple sclerosis, alemtuzumab (Lemtrada), reduced relapse rates by 49 percent and dropped the risk of sustained worsening of disabilities by 42 percent in patients treated in a pivotal, Phase 3 trial. The drug was tested in a … Continue reading “Genzyme MS Drug Significantly Reduces Relapse, Disability in Late-Stage Trial”
Reengineering Capitalism
In the fading months of 2011, we find ourselves in an uncertain world. On the one hand, America is still reeling from the 2008 financial crisis, and the nation’s faith in free-market capitalism as its guiding principle has been shaken to the core. On the other hand, Europe is reeling under the burdens of socialism … Continue reading “Reengineering Capitalism”
The Herman Cain-Inspired “1-100-0” Plan for Personalized Medicine?
You could feel Herman Cain’s presence last week on the biotech beat. And there was a lot of grousing about it. Cain, the Republican presidential candidate known for his simple 9-9-9 tax plan and some dubious extra-curricular activities, didn’t attend the Personalized Medicine Conference at Harvard Medical School. But a former advisor to President Obama, … Continue reading “The Herman Cain-Inspired “1-100-0” Plan for Personalized Medicine?”
Klip: iPhone Video Sharing Refined to A High Art
Put high-quality cameras into devices with broadband wireless connections. Add powerful smartphone operating systems like iOS or Android and app-store ecosystems like iTunes and the Android Market. Mix in some sloth and disinterest on the part of established photo-sharing destinations like Flickr, Facebook, and Twitter. Under these conditions, it was probably inevitable that entrepreneurs would … Continue reading “Klip: iPhone Video Sharing Refined to A High Art”
AMAG Stock Rises, Ariad Drug Shows Improved Safety, Rhythm Adds Merck Veteran as CEO, & More Boston-Area Life Sciences News
New England area biotechs had news this week on stock price, clinical data, new financings, and more. —AMAG Pharmaceuticals of Lexington, MA, saw its stock shoot up 18 percent to $16.21 on Monday after announcing its CEO Brian Pereira’s departure and its plans for reducing operating expenses. AMAG (NASDAQ: [[ticker:AMAG]]) has struggled in transitioning from … Continue reading “AMAG Stock Rises, Ariad Drug Shows Improved Safety, Rhythm Adds Merck Veteran as CEO, & More Boston-Area Life Sciences News”
Bluefin Labs and SocialGuide Push Competing Technology to Make Social Data Useful to TV Networks and Advertisers
It is not even Thanksgiving and it has already been a busy November for Bluefin Labs, a Cambridge, MA-based provider of analytics gleaned from the wealth of comments in the social sphere about television shows. Bluefin Labs, backed by Acacia Woods Ventures, Lerer Ventures, Redpoint Ventures, and others, was among the startups presenting their ideas … Continue reading “Bluefin Labs and SocialGuide Push Competing Technology to Make Social Data Useful to TV Networks and Advertisers”
Verastem Lands $20,102,609 New Funding Round
Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=7b74c493-ae4f-4383-8f65-53e541a2165c&Preview=1 Date 11/11/2011 Company Name Verastem Mailing Address 215 First Street Cambridge, MA 02142 Company Description Verastem, Inc. is a private biopharmaceutical company focused on discovering and developing novel drugs that selectively target cancer stem cells. Website http://www.Verastem.com Transaction Type Venture Equity Transaction Amount $20,102,609 Transaction Round Undisclosed Proceeds Purposes Proceeds purposes … Continue reading “Verastem Lands $20,102,609 New Funding Round”
Future of Robotics Summit
Reps from robotics research institutions around the state will take the stage at this MTLC event. Demos and tours of robotics research labs will follow the panels. Register here.
Calling Entrepreneurs for Sound Off, Round 2, at 6×6: Six Cities, Six Big Tech Ideas
We want you. To tell our audience what you want to see for the innovation community here in Boston. At Xconomy’s upcoming conference, 6×6: Six Cities, Six Big Tech Ideas. The Dec. 1 program, which features one cool tech company from each of our six cities, already has a top-notch line-up of speakers, like keynoter … Continue reading “Calling Entrepreneurs for Sound Off, Round 2, at 6×6: Six Cities, Six Big Tech Ideas”
Shareaholic Inks Seed Investment, Introduces Tumblr Plug-in
[Updated 11/10/11 10:35 am. See below.] Shareaholic, a Cambridge, MA-based maker of plug-ins for sharing content on the Web, has collected a $1.9 million round of seed funding, which will go to expanding the company’s team and publisher network. [Story updated to include specific funding amount.] The money comes from a collection of big-name angel … Continue reading “Shareaholic Inks Seed Investment, Introduces Tumblr Plug-in”
Collabor’s Software for Outward Collaboration at Businesses Ramps Up with First Outside Funding
It’s a big month for Collabor, a Maynard, MA-based maker of software that powers online communities—for banks, nonprofits, manufacturers and a slew of industries in between. The company is working on closing its first ever outside funding round and has just cross the 1-million-user mark across the sites its technology powers. The five-year-old startup is … Continue reading “Collabor’s Software for Outward Collaboration at Businesses Ramps Up with First Outside Funding”
Dusa Eyes Market Expansion for Skin Therapy Device
When Big Pharma veteran Robert Doman joined tiny Wilmington, MA-based Dusa Pharmaceuticals (NASDAQ: [[ticker:DUSA]]) in 2005, he found a company struggling to capitalize on a massive market opportunity. Dusa had won FDA approval in 2000 for a drug-device combination to treat actinic keratoses (AK), pre-cancerous skin growths. There are about 5 million cases of AKs treated … Continue reading “Dusa Eyes Market Expansion for Skin Therapy Device”
Shareaholic Garners $1,900,000 Seed Funding Round
Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=c880777f-7a2e-4def-a27c-48e60a74ab32&Preview=1 Date 11/10/2011 Company Name Shareaholic Mailing Address 486 Green Street Cambridge, MA 02139 Company Description Shareaholic makes it easy to save or share material found on the Web via common social networking, social bookmarking, and news aggregator services. Website http://www.shareaholic.com Transaction Type Venture Equity Transaction Amount $1,900,000 Transaction Round Seed Proceeds … Continue reading “Shareaholic Garners $1,900,000 Seed Funding Round”
Avaxia Biologics Secures $2,200,000 Series A Financing Round
Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=627cd2c1-d962-4b66-bfa9-cead3a68e96a&Preview=1 Date 11/10/2011 Company Name Avaxia Biologics Mailing Address 128 Spring Street Lexington, MA 02421 Company Description Avaxia is developing oral antibody products for diseases and disease targets that can be reached through the mouth and the gastrointestinal tract. Website http://www.avaxiabiologics.com Transaction Type Venture Equity Transaction Amount $2,200,000 Transaction Round Series A … Continue reading “Avaxia Biologics Secures $2,200,000 Series A Financing Round”
Seven Innovation Policy Ideas to Spark an Economic Recovery in the U.S.
In San Diego, Connect is the non-profit organization that reaches into most corners of the local innovation community. Connect likes to say that it has assisted in the formation of more than 3,000 technology and life sciences companies in the area, and more than 50 cities around the world have emulated its programs for mentoring … Continue reading “Seven Innovation Policy Ideas to Spark an Economic Recovery in the U.S.”
Rhythm Adds Former Merck VP as CEO
Merck veteran Keith Gottesdiener will become the new CEO of Boston-based Rhythm Pharmaceuticals, a Boston startup developing experimental drugs for the treatment of metabolic conditions such as obesity and diabetes, according to an announcement today. Gottesdiener oversaw pivotal clinical trials as Merck’s former vice president and late-sage therapeutic group leader, and is joining Rhythm as … Continue reading “Rhythm Adds Former Merck VP as CEO”
The Next Zuckerberg: A Student’s Recap of Mark’s Visit to Harvard
There, sitting about 10 feet in front of me, was the ninth most powerful person in the world, according to Forbes. Dressed in his signature t-shirt and jeans, you wouldn’t be able to tell Mark Zuckerberg apart from a random college student outside the lecture hall. As he took his seat and began speaking about … Continue reading “The Next Zuckerberg: A Student’s Recap of Mark’s Visit to Harvard”
Best Buy Picks Up MindShift, Termeer Funds NanoString, Basho Adds $5M More, & More Boston-Area Deals News
This week’s roundup of New England deals includes companies working on vocal cord repair, cancer stem cells, database software, IT services, and drug counterfeiting prevention. —Prolific MIT professor and inventor Bob Langer is working on a new project with a Harvard University surgeon that’s aiming to repair damaged vocal cords. The vibrating gel they’re developing … Continue reading “Best Buy Picks Up MindShift, Termeer Funds NanoString, Basho Adds $5M More, & More Boston-Area Deals News”
Vertex Stock Drops 17% Over Two Days, As Potent Hep C Rivals Emerge
Cambridge, MA-based Vertex Pharmaceuticals has seen its stock take a whopping 17 percent hit in the past two days at a scientific meeting, as investors have had time to think about the implications of new clinical trial data from a couple of competitors in the hepatitis C field. Vertex (NASDAQ: [[ticker:VRTX]]) saw its stock tumble … Continue reading “Vertex Stock Drops 17% Over Two Days, As Potent Hep C Rivals Emerge”
Amylin and Eli Lilly Part Ways on Diabetes Drug; Alkermes Deal Intact
San Diego’s Amylin Pharmaceuticals (NASDAQ: [[ticker:AMLN]])) and Eli Lilly today called a cease-fire to litigation that began earlier this year, and outlined an agreement to end the alliance they formed in 2002 to commercialize exenatide (Byetta), Amylin’s diabetes drug. A replay of Amylin’s conference call with analysts about the deal is available here. Amylin sued … Continue reading “Amylin and Eli Lilly Part Ways on Diabetes Drug; Alkermes Deal Intact”
PharmaSecure Combats Drug Counterfeiting, Armed With Funding From Eric Schmidt’s Innovation Endeavors
Nathan Sigworth was studying economics at Dartmouth College a few years back when he became fascinated with the problem of counterfeit drugs in developing countries. Plenty of technology had been developed to combat counterfeits—RFID tagging and the like—but it wasn’t affordable enough to be scaled up in places like India. “The technology that was out … Continue reading “PharmaSecure Combats Drug Counterfeiting, Armed With Funding From Eric Schmidt’s Innovation Endeavors”
The Wisdom of the Crowd: Social Networking Meets Capital Formation
Last year I had a chance to visit Washington D.C. and tour the Washington Monument. I later learned that this magnificent national icon was, in fact, an early example of crowd funding. Crowd funding is the process of aggregating small amounts of money from a large number of people in order to accomplish great things. … Continue reading “The Wisdom of the Crowd: Social Networking Meets Capital Formation”
Calcbench Looks to Help Budget-Minded Analysts Crunch Financial Data
Calcbench, a new startup working out of Cambridge, MA and New York, came to being from an app design challenge put on by the people behind XBRL, a technology standard the SEC requires public companies to use in reporting financial data. Yes, the terms app challenge and SEC did in fact appear in the same … Continue reading “Calcbench Looks to Help Budget-Minded Analysts Crunch Financial Data”
Arsenal Vascular Secures $3,000,000 New Funding
Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=800b2a1c-d094-42d0-8b67-386e319cc943&Preview=1 Date 11/8/2011 Company Name Arsenal Vascular Mailing Address 480 Arsenal Street Watertown, MA 02472 Company Description Arsenal Vascular is a privately-held biotechnology company focused on the development of therapeutic products based on its proprietary BioActive Composites platform. Website http://www.arsenalmedical.com Transaction Type Venture Equity Transaction Amount $3,000,000 Transaction Round Undisclosed Proceeds Purposes … Continue reading “Arsenal Vascular Secures $3,000,000 New Funding”
Kyruus Garners $2,999,989 New Funding Round
Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=f2ea63a5-ff79-4dbf-bec0-7f4b6f459d25&Preview=1 Date 11/8/2011 Company Name Kyruus Mailing Address 374 Congress St. Boston, MA 02210 Company Description Kyruus has developed a software platform that includes professional profiles of doctors and “big data” analytics. Website http://www.kyruus.com Transaction Type Venture Equity Transaction Amount $2,999,989 Transaction Round Undisclosed Proceeds Purposes Proceeds purposes were not disclosed. SEC … Continue reading “Kyruus Garners $2,999,989 New Funding Round”
Zeo Obtains $1,000,000 New Financing
Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=2f151b2c-8eed-44f3-a91a-dee6ee4659fe&Preview=1 Date 11/8/2011 Company Name Zeo Mailing Address 320 Nevada Street Floor 4 Newton, MA 02460 Company Description Our mission is to help people to discover new, scientifically-based ways to improve the quality of their lives through the power of sleep. We will accomplish this by combining breakthrough educational sleep technology and … Continue reading “Zeo Obtains $1,000,000 New Financing”
X-Body Secures $3,545,000 New Financing
Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=0961d8df-7373-4e43-a171-0924cbbc48b5&Preview=1 Date 11/8/2011 Company Name X-Body Mailing Address 100 Beaver Street Waltham, MA 02453 Company Description The company’s mission is to apply its innovative capabilities to the discovery of human antibodies against high-value therapeutic targets. X-BODY has entered into a number of alliances with other corporations to generate antibody therapeutic candidates. Website … Continue reading “X-Body Secures $3,545,000 New Financing”
MindShift Acquired by Best Buy as Retailer Expands IT Services
Best Buy is looking to a local IT services firm to spruce up its business, announcing today that it is acquiring Waltham, MA-based MindShift Technologies for $167 million. The deal gives Best Buy (NYSE: [[ticker:BBY]]) more power behind its services offering as the company faces competition in its retail operation from online sources like Amazon. … Continue reading “MindShift Acquired by Best Buy as Retailer Expands IT Services”
Ariad’s Second Cancer Drug Found Safer Than Expected in Early Review of Key Study
Ariad Pharmaceuticals CEO Harvey Berger has been fielding questions from investors for months about how much toxicity his company’s experimental cancer drug might be causing to the pancreas. The final verdict isn’t in yet, but an interim analysis being released today suggests the drug is safer than most thought it would be. The preliminary results … Continue reading “Ariad’s Second Cancer Drug Found Safer Than Expected in Early Review of Key Study”