Tolerx and Glaxo Diabetes Drug Disappoints in Late-Stage Study

There’s some bad news from Cambridge, MA-based Tolerx today. The venture-backed biotech firm and its partner GlaxoSmithKline (NYSE:[[ticker:GSK]]) reported that their experimental drug for Type 1 diabetes failed to meet the main clinical goal of a late-stage study, called Defend-1. The 272-patient Defend-1 study was designed to measure how well newly diagnosed adult patients were … Continue reading “Tolerx and Glaxo Diabetes Drug Disappoints in Late-Stage Study”

Report: Fabry Patients Sue Genzyme and Mt. Sinai Medical School

Six patients with the rare genetic disorder Fabry disease have filed a lawsuit against Cambridge, MA-based biotech company Genzyme (NASDAQ:[[ticker:GENZ]]) and Mt. Sinai Medical School over the handling of a rationing system for Genzyme’s Fabry treatment, agalsidase beta (Fabrazyme), the online publication Pharmalot reported yesterday. Genzyme, which is being bought by the French drug giant … Continue reading “Report: Fabry Patients Sue Genzyme and Mt. Sinai Medical School”

Getting Connected with James Fowler: Social Networks in the Real World and in Cyberspace

James Fowler says his work lies at the intersection of the natural and social sciences. As a professor in UC San Diego’s School of Medicine and Division of Social Sciences, his research encompasses social networks, behavioral economics, evolutionary game theory, political participation, and the genetic basis of political behavior. Fowler also is the co-author, with … Continue reading “Getting Connected with James Fowler: Social Networks in the Real World and in Cyberspace”

Epizyme Nabs Eisai Deal, Termeer Could Make $221.2M From Genzyme Buyout, Gates Funds Nimbus, & More Boston-Area Life Sciences News

We saw some meaty stories on Boston-area drug developers this week, as well as headlines about funding for newer healthcare and health IT startups. —Imprivata of Lexington, MA, is working on carving itself a niche in the crowded space of technology for the secure access of healthcare IT systems, Ryan wrote. The company, which has … Continue reading “Epizyme Nabs Eisai Deal, Termeer Could Make $221.2M From Genzyme Buyout, Gates Funds Nimbus, & More Boston-Area Life Sciences News”

Nimbit Garners $607,642 New Financing Round

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=42959497-b713-4489-af76-9776bf45d572&Preview=1 Date 3/11/2011 Company Name Nimbit Mailing Address 47 Mellen St. Framingham, MA 01702 Company Description Our mission is to put musical artists in complete control of their own music business and brand, enabling them to reach their full potential as quickly as possible. Website http://www.nimbit.com Transaction Type Venture Equity Transaction Amount … Continue reading “Nimbit Garners $607,642 New Financing Round”

Nimbit Secures $626,995 New Round

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=a2799a6b-6f31-46f9-bdb0-d92e1c3f6e53&Preview=1 Date 3/11/2011 Company Name Nimbit Mailing Address 47 Mellen St. Framingham, MA 01702 Company Description Our mission is to put musical artists in complete control of their own music business and brand, enabling them to reach their full potential as quickly as possible. Website http://www.nimbit.com Transaction Type Venture Equity Transaction Amount … Continue reading “Nimbit Secures $626,995 New Round”

WSJ Top 50 Startups List Leaves Much to Be Desired, Especially in Boston (NY Fares Better)

Everyone loves a Top 50 list. Everyone except me. Wall Street Journal, you can take your “Top 50 venture backed companies” list, published today, and…well, just take it. Not just because it counts a grand total of one—ONE—Boston-area company among its luminaries (Westborough, MA-based ExaGrid, at #42). Not just because the criteria for the list … Continue reading “WSJ Top 50 Startups List Leaves Much to Be Desired, Especially in Boston (NY Fares Better)”

Mobile Madness Speakers Dissect 4G, Enterprise Apps, New Interfaces; Zizzout Destealths with Mobile “Visual Marketplace”

If you can measure a conference’s success from the volume level during the closing cocktail hour, then Xconomy’s Mobile Madness forum yesterday in Cambridge, MA, was a smash. A record-setting crowd of more than 250 people headed to the Microsoft New England R&D Center Wednesday afternoon for the third annual edition of Xconomy’s half-day mobile … Continue reading “Mobile Madness Speakers Dissect 4G, Enterprise Apps, New Interfaces; Zizzout Destealths with Mobile “Visual Marketplace””

SCVNGR Rolls Out Location-Based Deals Service in Boston, Philadelphia

“SCVNGR is kind of a weird company.” That’s what it says in its press release today, so you know it’s true. And not only because it needs to buy a vowel. The Cambridge, MA, location-based gaming startup’s latest “weird” move is a potentially lucrative one. It is entering the local deals sector to compete with … Continue reading “SCVNGR Rolls Out Location-Based Deals Service in Boston, Philadelphia”

Clovr Snaps Up $8.3M

Clovr Media, a Boston-based digital and mobile marketing startup, announced today that it has brought in $8.3 million in a funding round led by Bain Capital Ventures managing director Jeffrey Glass. The round also included Clovr seed investors Kepha Partners and Common Angels, and newly announced angel investor Mark Wright. Clovr, which launched last October, … Continue reading “Clovr Snaps Up $8.3M”

Epizyme Takes $6M Upfront in Cancer Drug Deal with Eisai

Cambridge, MA-based Epizyme has nabbed another pharmaceutical partnership. Two months after announcing a deal worth as much as $650 million with GlaxoSmithKline (NYSE:[[ticker:GSK]]), the startup says today that it has landed a partnership with the Japanese drugmaker Eisai to develop drugs against an epigenetic enzyme for treating lymphomas and other cancers. In its latest deal, … Continue reading “Epizyme Takes $6M Upfront in Cancer Drug Deal with Eisai”

Forma, After Building Cancer Drug Discovery Engine, Makes First Big Bet on Starving Tumors

Forma Therapeutics could choose to do a lot of different things after spending its first couple years raising $50 million, forming a series of partnerships, and assembling a staff of 100 people around the world with all kinds of skills in the cancer drug R&D business. After all that, Cambridge, MA-based Forma has decided to … Continue reading “Forma, After Building Cancer Drug Discovery Engine, Makes First Big Bet on Starving Tumors”

Bill Gates Backs Nimbus, Betting on Computer-Based Drug Discovery

Here’s a startup that is stepping out of top-secret status in style. Microsoft Chairman Bill Gates, the second-most wealthy person in the world, is one of two new seed investors in the stealthy biotech startup, Nimbus Discovery. Cambridge, MA-based Nimbus, focused on computer-based drug discovery in partnership with the global chemical-simulation software provider Schrödinger, said … Continue reading “Bill Gates Backs Nimbus, Betting on Computer-Based Drug Discovery”

Clovr Media Garners $8,300,000 New Funding

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=9db9b449-2964-4d7b-af62-6c204bf30d48&Preview=1 Date 3/10/2011 Company Name Clovr Media Mailing Address 225 Franklin St., 26th Floor Boston, MA 02110 Company Description Card Linked Offers (CLOs) are the next generation of digital advertising. A seamless savings experience for consumers, CLOs offer a leap forward for Financial Institutions’ customer loyalty programs and a completely new form … Continue reading “Clovr Media Garners $8,300,000 New Funding”

Nimbus Discovery Garners New Financing Round

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=abe8b11b-af4c-41f0-8e0c-b0a56d36a27e&Preview=1 Date 3/10/2011 Company Name Nimbus Discovery Mailing Address 25 1st St. Cambridge, MA 02141 Company Description Nimbus Discovery is applying advances in computer-based drug discovery to unlock fundamental biological pathways. Nimbus has already delivered selective, potent, and differentiated compounds within the first year for two disease targets, IRAK4 and ACC, which … Continue reading “Nimbus Discovery Garners New Financing Round”

Intelligent Clearing Network Receives $1,000,000 New Funding

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=de7cc457-b86b-4fea-9ea4-11fbd63b1fa4&Preview=1 Date 3/10/2011 Company Name Intelligent Clearing Network Mailing Address 31 Lakeview Ave. New Canaan, CT 06840 Company Description ICN was founded by a team of software engineers and business managers who realized that the efficiency and fraud related to coupons was well documented and persistent. While digital couponing is by far … Continue reading “Intelligent Clearing Network Receives $1,000,000 New Funding”

Mobile Devices and Platforms Seminar

This morning event, sponsored by the Mass Technology Leadership Council, will take a close look at the different mobile platforms for developing apps: pros and cons, markets, support from the platform provdier, where to begin, and future opportunities. Sign up online for this one.

See You at Mobile Madness at Microsoft NERD: Be Ready for Anything

Hope you all had a fine Mardi Gras. Now it’s time to get down to business. Mobile business. Yes, Mobile Madness 2011 is happening this afternoon, over at Microsoft NERD in Kendall Square (the program starts at 1:00 pm). We’ve helped assemble some of the top names in the mobile industry from New England and … Continue reading “See You at Mobile Madness at Microsoft NERD: Be Ready for Anything”

$1M for Senior Health Startup Stonewedge

Stonewedge, an Andover, MA-based startup focused on improving care for seniors, has raised $1 million in an equity financing, according to an SEC filing. The company provides scant details about its business and products on its website. Stonewedge’s board includes Bernard Gordon, the founder and former chairman and CEO of Analogic (NASDAQ:[[ticker:ALOG]]), a maker of … Continue reading “$1M for Senior Health Startup Stonewedge”

ZeeVee Enhances Internet Video Portal for Connected Devices, Looks to Power Smaller Cable Providers

Littleton, MA-based ZeeVee has reinvented itself again. The startup launched four years ago to provide hardware for “bringing Internet television together and into the living room,” says CEO Vic Odryna. The ZvBox device didn’t exactly catch on in homes, but has found a niche in commercial settings like hotels, restaurants, and casinos. ZeeVee later introduced … Continue reading “ZeeVee Enhances Internet Video Portal for Connected Devices, Looks to Power Smaller Cable Providers”

Retroficiency, Backed by World Energy and Angels, Looks to Cash In on Real Estate Market for Energy Software

With a name like Retroficiency, you pretty much know what you’re getting. That’s saying a lot, given the obscurity of most startup names these days. You might gather that this company has to do with retrofitting and energy efficiency—and you’d be right. Boston-based Retroficiency provides software-as-a-service to help energy service companies, facility management firms, and … Continue reading “Retroficiency, Backed by World Energy and Angels, Looks to Cash In on Real Estate Market for Energy Software”

Kahoots Bought By RentJuice, Skyhook Enlists Sony, MassChallenge Adds $1M from MA, & More Boston-Area Deals News

We saw headlines of partnerships for Web and software companies, startup financings, and venture firms getting ready to raise bigger funds. —Boston-based mobile software maker Skyhook Wireless nabbed a deal with Sony to get its location-finding technology into Sony’s “NGP” handheld gaming system, expected to roll out in late 2011. Financial terms of the agreement … Continue reading “Kahoots Bought By RentJuice, Skyhook Enlists Sony, MassChallenge Adds $1M from MA, & More Boston-Area Deals News”

Chiasma Receives $4,000,000 New Financing

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=972a185a-cac5-4d34-bb4f-0f32c61f1868&Preview=1 Date 3/9/2011 Company Name Chiasma Mailing Address 831 Beacon St. Newton Center, MA 02459 Company Description Chiasma develops innovative solutions for the non-invasive delivery of protein drugs. Chiasma’s technology enables drugs to be administered into the bloodstream without the need for injections Website http://www.chiasmapharma.com Transaction Type Debt Transaction Amount $4,000,000 Transaction … Continue reading “Chiasma Receives $4,000,000 New Financing”

Euthymics Bioscience Secures $4,000,000 Series A Round

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=4f51a2b5-b2e1-4620-9be4-20b089aeb3ec&Preview=1 Date 3/9/2011 Company Name Euthymics Bioscience Mailing Address 43 Thorndike St. Cambridge, MA 02141 Company Description Euthymics Bioscience, Inc. is a neuroscience-focused clinical-stage company developing next-generation treatments for depression. Euthymics’ initial focus is on patients who do not respond adequately to SSRIs. EB-1010 for depression is expected to improve efficacy and … Continue reading “Euthymics Bioscience Secures $4,000,000 Series A Round”

Stonewedge Obtains $1,000,000 New Round

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=008db41c-54d6-4033-97fa-802f359647c7&Preview=1 Date 3/9/2011 Company Name Stonewedge Mailing Address 28 Andover St. Andover, MA 01810 Company Description Stonewedge is developing its core platform with a focus on the requirements of older adults, their care givers and families. Stonewedge products will elevate the delivery, quality and efficiency of health and wellness services provided to … Continue reading “Stonewedge Obtains $1,000,000 New Round”

Google Ventures, Sequoia, Salesforce Lead $32M Financing Round for HubSpot

[Updated 2:00 pm ET with additional perspective from the investors] Three Bay Area organizations are behind a big $32 million investment in Cambridge, MA-based marketing software company HubSpot. The Series D financing round, announced today, was led by Google Ventures, Sequoia Capital, and Salesforce.com, with Hubspot’s existing investors General Catalyst, Matrix Partners, and Scale Venture … Continue reading “Google Ventures, Sequoia, Salesforce Lead $32M Financing Round for HubSpot”

VC65 to Feature Tales of Great VCs and Entrepreneurs—Come Wish Venture Capital a Happy Birthday at MIT’s Kresge Auditorium

Great venture capitalists and entrepreneurs aren’t in it for the money or fame—they are out to build outstanding companies that make the world safer, healthier, more productive, more accessible, or just more fun. And, usually, it takes a great partnership between investors and entrepreneurs to pull that off. Celebrating such successful partnerships is the main … Continue reading “VC65 to Feature Tales of Great VCs and Entrepreneurs—Come Wish Venture Capital a Happy Birthday at MIT’s Kresge Auditorium”

Report: Genzyme Chief Could Reap $221.2M in Sanofi Deal

Genzyme chief executive Henri Termeer is due to take in $158.4 million from French drug giant Sanofi-Aventis’s buyout of his Cambridge, MA-based biotech firm, Bloomberg reported. Termeer is also eligible for up to $62.8 million from contingent value rights payments if Genzyme products such as the experimental multiple sclerosis drug alemtuzumab (Lemtrada) meet all performance … Continue reading “Report: Genzyme Chief Could Reap $221.2M in Sanofi Deal”

Netezza Chief Talks About “Formative” PTC Days, IBM Deal History, and the Future of Big Data

The name’s Baum. James Baum. OK, he might not be a dead ringer for 007, but I get the feeling Baum could handle himself in a firefight, high-stakes poker game, or dinner with the Queen, all with equal aplomb. He is a highly skilled pilot. He’s also pretty good with business intelligence, data warehouse appliances, … Continue reading “Netezza Chief Talks About “Formative” PTC Days, IBM Deal History, and the Future of Big Data”

Imprivata Aims to Make It Easier to Securely Access Electronic Health Records

Lexington, MA-based Imprivata is among the software companies that is benefiting from the push in the U.S. and abroad to adopt electronic health records. And the venture-backed company seems to have found its place in the healthcare field by streamlining the way clinicians securely access IT systems. This year, the U.S. government starts paying out … Continue reading “Imprivata Aims to Make It Easier to Securely Access Electronic Health Records”

Cortera Garners New Financing Round

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=f40a674e-d620-4098-bf74-0aaf275262b9&Preview=1 Date 3/8/2011 Company Name Cortera Mailing Address One Pine Hill Drive Batterymarch Park II Quincy, MA 02169 Company Description Cortera’s mission is to give you better, more actionable insights into the companies you deal with, without the hassle or high prices. It’s what we call Fresh Perspective. Website http://www.cortera.com Transaction Type … Continue reading “Cortera Garners New Financing Round”

RelayRides Receives $5,113,711 New Funding

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=f3f480d2-0460-47bc-be5a-380b3d0996fa&Preview=1 Date 3/8/2011 Company Name RelayRides Mailing Address 222 3rd St. Cambridge, MA 02141 Company Description The company operates a website and service that allows users to share automobiles. Website http://www.RelayRides.com Transaction Type Venture Equity Transaction Amount $5,113,711 Transaction Round Undisclosed Proceeds Purposes Proceeds purposes were not disclosed. SEC regulatory filing. M&A … Continue reading “RelayRides Receives $5,113,711 New Funding”

HubSpot Secures $32,000,000 Series D Funding

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=d8b4688b-55d2-4cfd-ae8a-9f22906708ca&Preview=1 Date 3/8/2011 Company Name HubSpot Mailing Address One Broadway 5th Floor Cambridge, MA 02142 Company Description HubSpot is an Internet marketing software platform that enables your company to get more leads from your website by driving more prospects to your website and converting more of them into leads. HubSpot software tracks … Continue reading “HubSpot Secures $32,000,000 Series D Funding”

Expressor Adds $4.5M

Burlington, MA-based Expressor Software has brought in $4.5 million in a debt-based offering, according to an SEC filing. Last May the data integration software provider raised $4.5 million from its previous investors, Commonwealth Capital Ventures, Globespan Capital Partners, and Sigma Partners.

WaySavvy, With Expedia Partnership, Joins New Wave of Online Travel Sites

A collaboration between New England and Northwest techies is aiming to radically improve the way people book flights and hotels on the Web. If all goes well, it will become part of a broader movement of tech companies looking to reshape the online travel landscape. I’m not talking about the alliance between Microsoft’s Bing Travel … Continue reading “WaySavvy, With Expedia Partnership, Joins New Wave of Online Travel Sites”

Advice Received, But Not Taken: Tales from the Biotech Trenches

Biotechnology is a challenging business, with drug development timelines that are long, costly, and dependent on the approval of government regulatory agencies. The vast majority of biotechs never succeed in developing a new drug. There are many issues that contribute to whether or not a company achieves its goals and makes it in the marketplace. … Continue reading “Advice Received, But Not Taken: Tales from the Biotech Trenches”

VC Analyst Turned Entrepreneur Looks to Bring Sophisticated Stock Market Data to Individual Investors with Screener.co

Former venture capital analyst Lenny Grover left his gig at Waltham, MA-based Longworth Venture Partners to make a sustainable business out of a personal hobby: sophisticated stock trading. No, he’s not working on yet another online trading platform, but is instead looking to the hot field of data and analytics to bring individual investors the … Continue reading “VC Analyst Turned Entrepreneur Looks to Bring Sophisticated Stock Market Data to Individual Investors with Screener.co”

Forget About the IPO Market: It’s Time for Biotechs To Think Differently

When a company like Plexxikon can’t pull off a big-time IPO, you know something’s out of whack in the biotech world. Berkeley, CA-based Plexxikon hit the motherlode last week when it agreed to be acquired for $805 million upfront, plus $130 million in milestones, by Japan-based Daiichi Sankyo. VCs everywhere drooled. That’s because in this … Continue reading “Forget About the IPO Market: It’s Time for Biotechs To Think Differently”

Expressor Software Secures $4,500,000 New Funding Round

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=b9f13791-1985-4816-8e7f-6bafa78b6a21&Preview=1 Date 3/7/2011 Company Name Expressor Software Mailing Address 1 New England Executive Park Burlington, MA 01803 Company Description The company provides multi-platform, parallel, processing, data management software. Website http://www.expressor-software.com Transaction Type Debt Transaction Amount $4,500,000 Transaction Round Undisclosed Proceeds Purposes Proceeds purposes were not disclosed. SEC regulatory filing. M&A Terms Venture … Continue reading “Expressor Software Secures $4,500,000 New Funding Round”

Stephen Wolfram’s Gadgets, The Future of Windows Phones, and Other Mobile Madness Themes: Tune In Next Week

Mobile Madness 2011 is happening next Wednesday, March 9, at Microsoft NERD in Cambridge, MA. Be there or be square. A couple of quick updates, before I return to the raging news-osphere. You can see the updated, detailed agenda for the conference here. —We’ve added Microsoft enterprise mobile specialist Anthony Kinney to the program. Here’s … Continue reading “Stephen Wolfram’s Gadgets, The Future of Windows Phones, and Other Mobile Madness Themes: Tune In Next Week”

Bing and Kayak Team Up Against Google

Kayak and Microsoft’s Bing Travel, once competitors in online travel meta-search, are now strategic partners. The companies announced today that in the coming weeks, Kayak will provide flight search results in the U.S. for Bing Travel. Financial terms were not given. Connecticut-based Kayak and Microsoft’s Bing were already allied against Google’s acquisition of Cambridge, MA-based … Continue reading “Bing and Kayak Team Up Against Google”

Three Kings: Bessemer, Greylock, Summit Raising Big New Funds

The big guys are getting bigger: Three prominent venture and private equity firms with Boston representation are in the news this week about raising big new funds. How does this affect startups and innovation? Probably not all that much, other than being part of the natural cycle of money flow. But it’s interesting, and possibly … Continue reading “Three Kings: Bessemer, Greylock, Summit Raising Big New Funds”

“Leonardo’s Notebook”—My Killer App for the iPad 2

Attention all mobile app developers: I’m about to give you an idea for a great new consumer app. I think it’s something that would appeal to any adventurous, creative, curious person—travelers, outdoorsmen, students, scrapbookers, artists, and the like. I think this is the moment to build it, since it’s something that wouldn’t have been possible … Continue reading ““Leonardo’s Notebook”—My Killer App for the iPad 2″

RXi Sells Stock and Warrants, Cardiorobotics Raises $6.6M, ImmunoGen Dishes On New Drugs, & More Boston-Area Life Sciences News

This week we’ve seen news of financings for device makers and drug developers, as well as reports from clinical trials from New England area life sciences firms and their rivals. —Daniel Junius, CEO of Waltham, MA-headquartered ImmunoGen, talked to Ryan about the antibody-based drugs the company is developing that aren’t generating as much noise as the … Continue reading “RXi Sells Stock and Warrants, Cardiorobotics Raises $6.6M, ImmunoGen Dishes On New Drugs, & More Boston-Area Life Sciences News”

Pluromed Lands $343,248 New Funding

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=8ede461f-5e6c-4058-94e1-101256887f74&Preview=1 Date 3/4/2011 Company Name Pluromed Mailing Address 25-H Olympia Avenue Woburn, MA 01801 Company Description Pluromed, Inc. is an early-stage medical technology company pioneering the use of injectable plugs to improve the safety, efficacy and economics of medical interventions. The Company develops, manufactures and markets a family of disposable medical devices … Continue reading “Pluromed Lands $343,248 New Funding”

Ruckus Media Drums Up $3.5M

Ruckus Media Group, a Norwalk, CT-based developer of children’s story mobile apps, announced today that it has brought in $3.5 million in a Series A financing led by San Francisco-based Alsop Louie Partners, with backing from other private investors. Ruckus, which launched in September, now has 15 children’s book apps on the Apple iTunes marketplace, … Continue reading “Ruckus Media Drums Up $3.5M”

Amylin, Lilly, Alkermes Diabetes Drug Doesn’t Match Rival in Head-to-Head Study

Three companies involved in the development of a once-weekly injection of the Type 2 diabetes drug exenatide reported today that the treatment did not provide superior efficacy over an existing treatment in a head-to-head study. Amylin Pharmaceuticals (NASDAQ:[[ticker:AMLN]]) of San Diego, Waltham, MA-based Alkermes (NASDAQ:[[ticker:ALKS]]), and Indianapolis drugmaker Eli Lilly (NYSE:[[ticker:LLY]]) said that the treatment, … Continue reading “Amylin, Lilly, Alkermes Diabetes Drug Doesn’t Match Rival in Head-to-Head Study”