Alkermes Wins FDA Panel Nod

Alkermes (NASDAQ: [[ticker:ALKS]]), the Waltham, MA-based biotech company, received some good news today from an FDA advisory panel. The FDA’s panel of psychiatric drug experts voted 12-1 to recommend that the FDA approve Alkermes’ long-lasting naltrexone (Vivitrol) as a treatment for opioid dependence. The FDA, which usually follows the recommendations of its advisory panels, has … Continue reading “Alkermes Wins FDA Panel Nod”

What We Can Learn from the Flight of Microsoft Execs to Amazon, AOL, GM, Nokia, Yahoo…and Micro VC

Sometimes all you need to do is look at where former Microsoft executives are going, to piece together some interesting trends in the tech industry. In recent months, a number of high-profile leaders from very different divisions of the Redmond, WA-based software firm (NASDAQ: [[ticker:MSFT]]) have departed. This might be true in any given year … Continue reading “What We Can Learn from the Flight of Microsoft Execs to Amazon, AOL, GM, Nokia, Yahoo…and Micro VC”

Entrepreneurial Walk of Fame Gets Some Legs at Cambridge City Hall Meeting

What happens when entrepreneurship meets politics? A task force forms and an idea inches its way forward. The idea I’m talking about is an Entrepreneurial Walk of Fame, akin to Hollywood’s celebration of movie stars, in Cambridge’s own Kendall Square, a proposal that Xconomy’s CEO Bob Buderi first wrote about last month. MIT Entrepreneurship Center … Continue reading “Entrepreneurial Walk of Fame Gets Some Legs at Cambridge City Hall Meeting”

A Closer Look at IBM’s Recent Massachusetts Acquisitions—Some Trends and Analysis

Yesterday, IBM announced it is acquiring Waltham, MA-based OpenPages, a corporate governance, risk, and compliance software company. That’s an interesting story in itself, but it’s also part of a prominent business trend that has major impact on the New England software and computing ecosystem. OpenPages is IBM’s 17th acquisition of a company based in Massachusetts … Continue reading “A Closer Look at IBM’s Recent Massachusetts Acquisitions—Some Trends and Analysis”

Skyhook, Fighting for Its Life in Suit Against Google, Cries Foul: “Call in the Referees and Review the Tape”

Boston-based Skyhook Wireless, in what could be a fight for its life, is taking a double-barreled legal shot at Google. In a pair of lawsuits filed against the search and advertising giant yesterday, the seven-year-old, 32-employee startup says Google illegally copied its location-finding technology and then leaned on business partners to use Google’s version instead … Continue reading “Skyhook, Fighting for Its Life in Suit Against Google, Cries Foul: “Call in the Referees and Review the Tape””

Aylus Networks Receives $4,000,000 New Financing Round

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=3afdb8db-e25e-49c8-92c9-e06d90724e95&Preview=1 Date 9/16/2010 Company Name Aylus Networks Mailing Address 238 Littleton Road Westford, MA 01886 Company Description Aylus has developed revolutionary share services that will transform the way mobile subscribers communicate in emerging wireless networks. Website http://www.aylus.com Transaction Type Debt Transaction Amount $4,000,000 Transaction Round Undisclosed Proceeds Purposes Proceeds purposes were not … Continue reading “Aylus Networks Receives $4,000,000 New Financing Round”

Volcano Capital, BioVentures, Omega Funds Acquires Hydrocision for Undisclosed Sum

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=4e937e64-fcd3-4058-9d5b-b24200ac23c3&Preview=1 Date 9/16/2010 Company Name Hydrocision Mailing Address 267 Boston Road North Billerica, MA 01862 Company Description HydroCision is the leading developer, manufacturer, and marketer of fluid-jet based surgical tools for the spine market. Incorporated in 1994, HydroCision s proprietary fluidjet technology is the basis of a new surgical modality leveraging compelling … Continue reading “Volcano Capital, BioVentures, Omega Funds Acquires Hydrocision for Undisclosed Sum”

Fierce 15 Shines Light on Some of Our Favorite Companies in Boston and Beyond

I’ve never actually met the folks at FierceBiotech in person, but today I felt like we had undergone some kind of Vulcan mind meld. The online industry publication unveiled its annual Fierce 15 list of the 15 most promising private biotech companies in the U.S. What jumped out at me right away? All but one … Continue reading “Fierce 15 Shines Light on Some of Our Favorite Companies in Boston and Beyond”

Bluebird Bio, Third Rock & Genzyme’s Gene Therapy Bet, Shows Promise for Blood Disorder

Genzyme and Third Rock Ventures bet $35 million six months ago on a Cambridge, MA-based gene therapy company. Despite all the ups and downs with gene therapy over the years, now we can see why they placed the bet. The newly renamed Bluebird Bio, formerly known as Genetix Pharmaceuticals, is coming out today with an … Continue reading “Bluebird Bio, Third Rock & Genzyme’s Gene Therapy Bet, Shows Promise for Blood Disorder”

IBM Buys OpenPages, 17th Massachusetts Acquisition Since 2003

Waltham, MA-based OpenPages, a maker of business software for managing corporate risk and compliance activities, is being acquired by IBM for an undisclosed sum. Armonk, NY-based IBM announced the news in a press release this morning. Once the acquisition closes, IBM (NYSE: [[ticker:IBM]]) says it will integrate OpenPages into its Business Analytics software portfolio. This … Continue reading “IBM Buys OpenPages, 17th Massachusetts Acquisition Since 2003”

Tetraphase Shows What the $45M Was All About at Big Antibiotics Conference

Tetraphase Pharmaceuticals raised a big $45 million venture round back in June, and now scientists can see more clearly why it’s been able to raise all that dough. The Watertown, MA-based company made a series of 10 different poster presentations over the past few days at the biggest antibiotics meeting of the year, the Interscience … Continue reading “Tetraphase Shows What the $45M Was All About at Big Antibiotics Conference”

Grasshopper Group Rolls Out Spreadable, A New Way to Create Buzz at the Brand Level

It’s common advice in the tech startup world that entrepreneurs should focus on developing solutions to problems that they’d like to see fixed, rather than look to innovating in more obscure areas. Needham, MA-based Grasshopper Group definitely follows this ethic. The startup has a suite of technology answers to basic entrepreneurial business problems, such as … Continue reading “Grasshopper Group Rolls Out Spreadable, A New Way to Create Buzz at the Brand Level”

Notes from the Opening of A123Systems’ Michigan Manufacturing Plant

Under cloudless blue skies in Livonia, MI, many of those at the forefront of electrification of vehicles gathered on Monday to celebrate the opening of A123 Systems’ lithium ion battery manufacturing plant. From political leaders to business executives and scientists, an array of notable speakers highlighted new and important progress on advanced batteries and vehicle … Continue reading “Notes from the Opening of A123Systems’ Michigan Manufacturing Plant”

Genzyme Sheds Testing Unit, Red Bend Acquires VirtualLogix, Acceleron Forges Alliance with Shire, & More Boston-Area Deals News

New England’s life sciences companies inked the majority of this week’s deals, but several software firms had interesting business to report as well. —Boston-based startup Rhythm Pharmaceuticals completed its Series A financing round with a total of $40 million. Third Rock Ventures participated in the closing, joining MPM Capital and New Enterprise Associates, who led … Continue reading “Genzyme Sheds Testing Unit, Red Bend Acquires VirtualLogix, Acceleron Forges Alliance with Shire, & More Boston-Area Deals News”

IBM Acquires OpenPages for Undisclosed Sum

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=2771851c-c1fb-499a-93a6-693041db799e&Preview=1 Date 9/15/2010 Company Name OpenPages Mailing Address 201 Jones Road Waltham, MA 02451 Company Description OpenPages develops enterprise compliance management solutions that streamline knowledge-intensive processes to improve corporate accountability, reduce disclosure process cost, enhance internal controls management productivity, and increase investor confidence. Website http://www.openpages.com Transaction Type M&A Transaction Amount Undisclosed Transaction … Continue reading “IBM Acquires OpenPages for Undisclosed Sum”

Lantos Technologies Garners $1,599,999 New Financing

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=3bf6b08d-b97c-4371-be20-e13fc0c8b1b4&Preview=1 Date 9/15/2010 Company Name Lantos Technologies Mailing Address One Broadway, 14th Floor Cambridge, MA 02142 Company Description Lantos Technologies is working to commercialize a 3D digital scanner capable of measuring ear canal shape and tissue compliance. This method will eliminate the uncertainties associated with manual fits, greatly improving the performance of … Continue reading “Lantos Technologies Garners $1,599,999 New Financing”

SimpliVT Brings in $9.2M

SimpliVT, a Waltham, MA-based stealth-mode startup founded by software entrepreneur Doron Kempel, has wrapped up a $9.2 million equity-based round of funding from eight unnamed investors, according to an SEC filing. The company does not yet have a website revealing its products or technology, though Kempel told me on the phone that his startup is … Continue reading “SimpliVT Brings in $9.2M”

Play140 Looks Into the Future of Social Gaming, Sees the Past (Text-Based Games)

The grand ballroom of the Royal Sonesta hotel in Cambridge, MA, was jam-packed last night and had a collective energy that I haven’t felt in a long time. Hundreds of people were on hand for the Web Innovators Group meeting, organized by venture capitalist David Beisel (formerly of Venrock, now with NextView Ventures). I had … Continue reading “Play140 Looks Into the Future of Social Gaming, Sees the Past (Text-Based Games)”

Joule Gets Biofuel Bacteria Patent

Cambridge, MA-based Joule Unlimited, a biofuels technology company, announced today it has been granted a U.S. patent for an engineered bacterium that produces liquid hydrocarbon fuels from sunlight and carbon dioxide. The company says it is the first to patent a direct, single-step, continuous process (based on photosynthesis) for producing hydrocarbon fuels without using raw … Continue reading “Joule Gets Biofuel Bacteria Patent”

Lightower Buys Lexent

Boxborough, MA-based Lightower Fiber Networks, a bandwith service provider and operator of data-transporting fiber networks, said today that it is acquiring New York City-based Lexent Metro Connect, which provides custom-built dark fiber networks. The company is not revealing how much it paid for Lexent, but has said that the acquisition will expand its base in … Continue reading “Lightower Buys Lexent”

Punchbowl Changes Domain Name, Looks to Prevail in Tough Climate for Parties

Here’s an interesting snapshot of a lean, consumer-oriented Internet startup that has survived the recession so far—and is looking to take its business to a new level. Framingham, MA-based Punchbowl Software, an online party-planning company, said today it has surpassed one million registered users as of a few weeks ago. That number includes senders and … Continue reading “Punchbowl Changes Domain Name, Looks to Prevail in Tough Climate for Parties”

Who Knew? Part 3: Xconomy Uncovers Even More Strange-But-True Facts About Boston’s Innovation Leaders

We’re back! After a long hiatus, Xconomy has returned with more strange-but-true facts from the world of New England innovation. And in this latest installment, our third so far, things are getting seriously offbeat. Who once acted as press secretary for not one, but two of the four leaders of the Tiananmen Square revolt—and which … Continue reading “Who Knew? Part 3: Xconomy Uncovers Even More Strange-But-True Facts About Boston’s Innovation Leaders”

Jonathan Bush and Girish Navani, Two Major Figures in Health IT, to Headline Xconomy Xchange

There are literally billions of dollars at stake in this contest: Across the U.S., electronic health records (EHR) vendors are hustling to get physicians to buy their products as the federal government forges ahead with a multibillion-dollar effort to increase usage of the records. The race was ignited by the February 2009 passage of the … Continue reading “Jonathan Bush and Girish Navani, Two Major Figures in Health IT, to Headline Xconomy Xchange”

Tryton Medical Obtains $20,000,000 Series D Round

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=7cc371ca-a6bc-4e1e-a69f-5a7dbb20258b&Preview=1 Date 9/14/2010 Company Name Tryton Medical Mailing Address 1000 Park Forty Plaza Durham, MA 27713 Company Description Tryton Medical, Inc. is the leading developer of stents that are designed to definitively treat bifurcation lesions. 540,000 bifurcation coronary lesions are sub-optimally treated every year with a variety of time consuming and technically … Continue reading “Tryton Medical Obtains $20,000,000 Series D Round”

SimpliVT Lands $9,189,000 New Round

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=9adc7a90-1baf-45a1-ace8-2b8283df6607&Preview=1 Date 9/14/2010 Company Name SimpliVT Mailing Address 850 Winter Street Waltham, MA 02451 Company Description Undisclosed Website Undisclosed Transaction Type Venture Equity Transaction Amount $9,189,000 Transaction Round Undisclosed Proceeds Purposes Proceeds purposes were not disclosed. SEC regulatory filing. M&A Terms Venture Investor Undisclosed

Boston Big Data Summit

From the event website: “The Boston Big Data Summit is a forum for Boston-area end users, vendors and investors interested in Big Data applications.  Our 3-hour evening meetings aim to give busy database professionals the opportunity to stay on top of Big Data topics, share in-the-trench experiences and network with peers.” Information and registration here.

Ironwood Pharma Passes Third Big Clinical Trial With Constipation Drug, Shares Climb

Ironwood Pharmaceuticals went public earlier this year after passing its first two pivotal clinical trials. Now the company has cleared its third major clinical hurdle, which sent the Cambridge, MA-based company’s shares (NASDAQ:[[ticker:IRWD]]) up by more than 15 percent in after-hours trading. Ironwood’s experimental drug reached its goal of relieving abdominal pain/discomfort and helping reduce … Continue reading “Ironwood Pharma Passes Third Big Clinical Trial With Constipation Drug, Shares Climb”

UTest Raises its Largest Round Yet, $13 Million, to Scale Up Crowdsourced Software Testing Community

UTest, which helps big companies crowdsource their software quality assurance (QA) testing to a community of 30,000 freelance testers, said today that it has raised $13 million in Series C financing. It’s one of the largest venture funding rounds ever collected by a crowdsourcing company, and from the size of the round, “you should take … Continue reading “UTest Raises its Largest Round Yet, $13 Million, to Scale Up Crowdsourced Software Testing Community”

Book of Odds, With Book Deal in Tow, Is Updating Website to Help Consumers Make Sense of Risks in Everyday Life

The Book of Odds isn’t betting its future on any one thing, and founder and president Amram Shapiro see that as one of its strengths. “A lot of websites and startups are one-trick ponies,” Shapiro says. “Everything really has to work or pretty much they’re out of it. We think of ourselves as a 10- … Continue reading “Book of Odds, With Book Deal in Tow, Is Updating Website to Help Consumers Make Sense of Risks in Everyday Life”

Third Rock Ventures Secures $426M Second Fund, Makes Changes to Partner Ranks

Third Rock Ventures, a healthcare-focused venture firm with offices in Boston and San Francisco, says today it has raised $426 million for its second fund. The fund represents a vote of support for the firm’s model of investing in and starting life sciences ventures that have the potential to transform healthcare. The Boston-based firm, which … Continue reading “Third Rock Ventures Secures $426M Second Fund, Makes Changes to Partner Ranks”

Genzyme Agrees to Sell Genetics Unit to LabCorp for $925M

Cambridge, MA-based biotech powerhouse Genzyme (NASDAQ: [[ticker:GENZ]]) has struck a deal to sell its laboratory testing unit to Laboratory Corporation of America for $925 million in cash, the company reported this morning. The move is part of a plan to win over shareholders and comes after the French drug maker Sanofi-Aventis made an unsolicited offer … Continue reading “Genzyme Agrees to Sell Genetics Unit to LabCorp for $925M”

A123 Opens Lithium Ion Battery Plant in Michigan, Wants to Create Global Hub for Electric Vehicles

Big companies put on dog-and-pony shows for government officials all the time, but this one actually means something. A123Systems (NASDAQ: [[ticker:AONE]]), based in the Boston area, is officially opening a 291,000-square-foot lithium ion battery manufacturing facility in Livonia, MI, today. The plant already employs more than 300 people, and is part of a Michigan expansion … Continue reading “A123 Opens Lithium Ion Battery Plant in Michigan, Wants to Create Global Hub for Electric Vehicles”

PerkinElmer Expects to Make Acquisitions After $500M Business Sale: CEO Talks Boston-Area Talent and Growth in Software, Imaging

PerkinElmer has recently struck a deal that it hopes will fuel its growth in the human and environmental health markets, among other things. Rob Friel, the chairman and chief executive of the Waltham, MA-based maker of lab analytical tools, gave me his personal take on his firm’s (NYSE: [[ticker:PKI]]) sale of its illumination and detection … Continue reading “PerkinElmer Expects to Make Acquisitions After $500M Business Sale: CEO Talks Boston-Area Talent and Growth in Software, Imaging”

uTest Obtains $13,000,000 New Financing

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=5682bba5-5bce-4f29-b3f5-cf9f570c8b29&Preview=1 Date 9/13/2010 Company Name uTest Mailing Address 153 Cordaville Rd Southborough, MA 01772 Company Description uTestTM is revolutionizing traditional software testing by introducing the first global marketplace for software application testing coupled with a Pay Per Bug business model. Website http://www.utest.com Transaction Type Venture Equity Transaction Amount $13,000,000 Transaction Round Undisclosed … Continue reading “uTest Obtains $13,000,000 New Financing”

Paloma Pharmaceuticals Secures $1,200,000 New Financing

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=12fb9309-02a5-4aed-83bb-585ef7a88e05&Preview=1 Date 9/12/2010 Company Name Paloma Pharmaceuticals Mailing Address 37 Neillian Crescent Jamaica Plain, MA 02130 Company Description Paloma Pharmaceuticals, Inc. is an early stage drug development company focusing on pathologies with a vascular component including cancer, ocular diseases (macular degeneration and diabetic retinopathy), arthritis, fibrotic diseases (pulmonary fibrosis) endometriosis, osteoporosis and … Continue reading “Paloma Pharmaceuticals Secures $1,200,000 New Financing”

Genzyme Cutting 1,000 Jobs Over Next 15 Months

Cambridge, MA-based Genzyme (NASDAQ: [[ticker:GENZ]]) is cutting 1,000 jobs over the next 15 months, as it faces intense pressure from shareholders to recover from manufacturing woes and deal with a takeover bid from Paris-based drug giant Sanofi-Aventis. Genzyme CEO Henri Termeer described the job cut plan this morning in a memo to employees. The layoffs … Continue reading “Genzyme Cutting 1,000 Jobs Over Next 15 Months”

Google’s Street View “Trike” at Faneuil Hall Today: Q&A with Digital Imaging Mastermind Luc Vincent

If you’re in the Faneuil Hall area of Boston today, look out for the trike. That would be the Google Street View Trike, a pedicab-like contraption mounted with a camera and computer equipment. It’s meant to capture 360-degree, street-level images of places where Google’s fleet of Street View cars can’t go—pedestrian malls, university campuses, parks, … Continue reading “Google’s Street View “Trike” at Faneuil Hall Today: Q&A with Digital Imaging Mastermind Luc Vincent”

Google Instant Is Anything But a Time-Saver

At a press event in San Francisco this week, Google introduced Google Instant, an overhaul of its core search engine that brings up location- and history-sensitive search results even before you’ve finished typing your query. If you live in San Francisco and you type “s-a-u,” for example, Google Instant will make an educated guess that … Continue reading “Google Instant Is Anything But a Time-Saver”

Good Start Genetics Emerges from Stealth with $18M Series A Round

Good Start Genetics is making boosters from all corners of the life sciences sector in Massachusetts look really good today. The Boston-based startup, which is developing genetic tests for prospective parents, says today that it has finished raising an $18 million Series A round of funding. There appear to be a number of people and … Continue reading “Good Start Genetics Emerges from Stealth with $18M Series A Round”

Pfizer Axes Celldex Agreement, Vertex’s Telaprevir Performs in Clinical Trial, Anchor Therapeutics Inks Potential $480M Deal With J&J, & More Boston-Area Life Sciences News

—Needham, MA-based Celldex Therapeutics announced that Pfizer (NYSE: [[ticker:PFE]]) had terminated a agreement in which it licensed Celldex’s experimental cancer vaccine rindopepimut, because it no longer views the drug as a strategic priority. Celldex (NASDAQ: [[ticker:CLDX]]) will regain full rights to develop and commercialize the drug, effective November 1. —Ryan checked in with Oliver Fetzer, … Continue reading “Pfizer Axes Celldex Agreement, Vertex’s Telaprevir Performs in Clinical Trial, Anchor Therapeutics Inks Potential $480M Deal With J&J, & More Boston-Area Life Sciences News”

Allied Minds Injects $3 Million Into Ann Arbor-based Biotectix to Support Conductive Polymer Technology for Implantable Medical Devices

Allied Minds, which makes seed investments in technology developed at universities and national labs, said yesterday it has invested $3 million in Ann Arbor, MI-based Biotectix to advance research and development of its novel conductive polymer technology. The company, which was formed out of the University of Michigan, is working on polymer materials and coatings … Continue reading “Allied Minds Injects $3 Million Into Ann Arbor-based Biotectix to Support Conductive Polymer Technology for Implantable Medical Devices”

Good Start Genetics Obtains $18,000,000 Series A Funding

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=9304c337-2cda-49bd-a12f-51a56589555c&Preview=1 Date 9/10/2010 Company Name Good Start Genetics Mailing Address 8 St. Mary’s Street Boston, MA 02215 Company Description Good Start Genetics’ advanced DNA sequencing technology is designed to deliver a higher detection rate and improved clinical performance compared to currently available screening methods. Website http://www.goodstartgenetics.com Transaction Type Venture Equity Transaction Amount … Continue reading “Good Start Genetics Obtains $18,000,000 Series A Funding”

Angel Boot Camp, Project 11, and Hacker Angels Meet at a Startup Called Locately

Normally, we wouldn’t get too excited about a $300,000 tech startup financing in Boston. We might write a brief, or save it for a deal roundup. But today’s news that Locately, a Boston-based location analytics firm, has raised a seed round touches on several important local innovation themes and organizations. Consider the following: —One of … Continue reading “Angel Boot Camp, Project 11, and Hacker Angels Meet at a Startup Called Locately”

CombinatoRx Becomes Zalicus

Cambridge, MA-based drug developer CombinatoRx announced today that it has changed its name to Zalicus to better reflect its assets and focus, following its merger last year with Vancouver-based Neuromed Pharmaceuticals. The company garnered its first drug approval earlier this year for the pain treatment hydromorphone HCL (Exalgo), which is being marketed by healthcare products … Continue reading “CombinatoRx Becomes Zalicus”

Powerhouse Dynamics, With Another $400K, Is Out to Monitor Energy Use at the Circuit Level and Sell Through Dealers

Not using energy you don’t need has become an attractive way of going green, and has given birth to companies out to track and target your energy consumption, or retrofit your home for greater efficiency. Newton, MA-based Powerhouse Dynamics, founded in 2008, is a player in the energy-monitoring software field, but it’s been going about … Continue reading “Powerhouse Dynamics, With Another $400K, Is Out to Monitor Energy Use at the Circuit Level and Sell Through Dealers”

Prelert Raises $3.75M to Manage IT Incidents

Needham, MA-based Prelert, a maker of IT analysis and incident management software, announced it has raised $3.75 million in Series A financing from Fairhaven Capital Partners and Sierra Ventures. Prelert says its software helps companies identify the cause of IT service disruptions (for things like Web applications) much faster than existing approaches. The technology uses … Continue reading “Prelert Raises $3.75M to Manage IT Incidents”

Acceleron Snags $498M Deal With Shire to Develop Muscular Dystrophy Drugs

Shire has got to be feeling a little extra bounce in its step, as one of its competitors (Genzyme) has wobbled recently, and today it’s continuing its bold push forward in the world of rare diseases in a big partnership with Cambridge, MA-based Acceleron Pharma. Shire (NASDAQ: [[ticker:SHGPY]]), the U.K-based company that’s become an increasingly … Continue reading “Acceleron Snags $498M Deal With Shire to Develop Muscular Dystrophy Drugs”