The Chinese scientist He Jiankui, who revealed last fall that he used CRISPR gene editing to try to make twin newborn girls immune to HIV infection, might have also given them a higher risk of death. That’s according to a new study from University of California, Berkeley data scientists who analyzed the records of more … Continue reading “Study: Gene Edits in CRISPR Babies Could Boost Risk of Earlier Death”
Category: Detroit
Bio Roundup: Opioids in Court, IPO Parade, Brain Cancer Bet & More
[Corrected 5/31/19, 8:48 am ET. See below.] Pharmaceutical companies that make or market opioids have found themselves in legal hot water, and much of the heat is coming from Oklahoma. This week, a trial began litigating Johnson & Johnson’s responsibility for opioid addiction in the Sooner State. Johnson & Johnson (NYSE: [[ticker:JNJ]]) entered the Norman, … Continue reading “Bio Roundup: Opioids in Court, IPO Parade, Brain Cancer Bet & More”
Quantum Computing 101: Brilliant, Google, Microsoft Training Workers
From Microsoft and IBM to Alphabet’s unit X and Canada’s D-Wave Systems, companies are racing to build powerful quantum computers that may solve problems beyond the capacity of the most sophisticated conventional processors, and do it much faster. It’ll be some years before such uber-computers are robust and reliable enough for broad commercial use. But … Continue reading “Quantum Computing 101: Brilliant, Google, Microsoft Training Workers”
Wayne State Is MI Mobility Institute’s First Educational Partner
The Michigan Mobility Institute, an organization working to create a new crop of mobility professionals with skills in artificial intelligence, robotics, cybersecurity, and other related fields, has chosen its inaugural educational partner. Jessica Robinson, the institute’s executive director, says Wayne State University’s College of Engineering will lead development of a graduate-level advanced mobility education curriculum. … Continue reading “Wayne State Is MI Mobility Institute’s First Educational Partner”
Agenda Posted for Net@50 on July 16 at MIT Media Lab
Come celebrate milestones the internet has made over the past 50 years at a special event called Net@50 on July 16 in Cambridge, MA, organized by the World Frontiers Forum and Xconomy. An afternoon forum at the MIT Media Lab will explore the big issues and challenges surrounding the internet. And a gala dinner at … Continue reading “Agenda Posted for Net@50 on July 16 at MIT Media Lab”
Can Tiny Drug Doses (and One Woman’s Fortune) Fight the Most Vicious Cancer?
When the brain goes bad, modern medicine is often powerless to help. That’s the case for Alzheimer’s disease, where drug after drug has failed, and the only approved treatments are marginally helpful at best. The same seems increasingly clear for the most common and aggressive type of brain cancer, glioblastoma multiforme. Its origins are mysterious, … Continue reading “Can Tiny Drug Doses (and One Woman’s Fortune) Fight the Most Vicious Cancer?”
Immunotherapy Is Now Here For Breast Cancer. What Are Its Prospects?
Drugs that rev up a patient’s immune system have changed how we treat cancers of the skin, lung, and more, offering people whose tumors have spread a chance to live longer than ever thought possible. But until this year, the field had nothing for breast cancer, which kills more women than any other cancer type. … Continue reading “Immunotherapy Is Now Here For Breast Cancer. What Are Its Prospects?”
Second US Gene Therapy, Approved for Rare Muscle Disease, to Cost $2M
The FDA today has made Zolgensma, a Novartis treatment for the rare genetic disease spinal muscular atrophy, the second approved gene therapy in the US. The news marks a milestone for SMA patients, who have only one other approved medicine available. But it comes with a cost: At $2.125 million, Zolgensma’s price tag creates a … Continue reading “Second US Gene Therapy, Approved for Rare Muscle Disease, to Cost $2M”
Bio Roundup: Zolgensma Watch, Brain Cancer Blues, Peloton Payout & More
Patients, doctors, family members, and drug-price watchdogs continued to wait for the expected approval of Zolgensma, a Novartis (NYSE: [[ticker:NVS]]) gene therapy for the rare inherited disease spinal muscular atrophy. Originally developed at a children’s hospital in Ohio, Zolgensma will be a litmus test for the nascent field. If approved this week or next, it … Continue reading “Bio Roundup: Zolgensma Watch, Brain Cancer Blues, Peloton Payout & More”
Scoop Partners with Bedrock to Bring Carpooling Service to Detroiters
Scoop, the app-based carpooling service headquartered in San Francisco, landed in Detroit this week and will now facilitate rides for residents living in seven Motor City ZIP codes that encompass downtown, Midtown, Corktown, and neighborhoods to the immediate east and west of downtown. When Scoop enters a new market, its approach involves partnering with a … Continue reading “Scoop Partners with Bedrock to Bring Carpooling Service to Detroiters”
Despite Industrial Tech’s Growing Sophistication, US Adoption Lags
This week, Detroit is hosting SME’s RAPID + TCT event, a conference and trade show dedicated to additive manufacturing, commonly known as 3D printing. It’s the first time the conference, which draws attendees from across the world, has been held in Detroit since 2014. Maria Conrado, SME’s senior event manager, says the conference has grown … Continue reading “Despite Industrial Tech’s Growing Sophistication, US Adoption Lags”
AI Startup Clinc Snags $52M Series B to Expand Offices, Markets
Ann Arbor, MI-based startup Clinc, which is focused on developing conversational artificial intelligence software for use in chatbots, has raised $52 million in a Series B round, the company announced this week. The round was led by Insight Partners, with participation from DFJ Growth, Drive Capital, and Hyde Park Venture Partners. As part of the … Continue reading “AI Startup Clinc Snags $52M Series B to Expand Offices, Markets”
Sebastian Thrun and Udacity Launch New Self-Driving Nanodegree
[Corrected 5/21/19, 11:04 am. See below.] Sebastian Thrun first made his mark on autonomous vehicle development at the dawn of that industry, when he led a Stanford team whose robot car Stanley won the $2 million DARPA Grand Challenge in 2005 by racing driverless through the Mojave Desert for 132 miles. These days, Thrun seems … Continue reading “Sebastian Thrun and Udacity Launch New Self-Driving Nanodegree”
HAP Partners With Livongo on Tech-Enabled Diabetes Compliance Program
As digital health applications continue to grow in popularity, yet achieve only mixed results, one area in which tech-enabled tools have found success is among diabetes patients. Health Alliance Plan (HAP), a Detroit-based nonprofit health insurance provider, wants to leverage that success with a new program in partnership with Mountain View, CA-based Livongo, maker of … Continue reading “HAP Partners With Livongo on Tech-Enabled Diabetes Compliance Program”
PlanetM Awards New Grants to Advance Mobility Pilots in Michigan
PlanetM, the state of Michigan-backed business development organization, has announced a new batch of grants that aim to entice mobility startups and corporations to pilot their innovations in Michigan, or test and validate their technology at one of Michigan’s proving grounds. PlanetM has awarded a total of $440,000 in grants to five companies. The startups … Continue reading “PlanetM Awards New Grants to Advance Mobility Pilots in Michigan”
Bio Roundup: Generic Drugs Graft, ASCO Ahead, ElevateBio Rises & More
Generic drugs are supposed to give consumers more choices and a counterweight to more costly branded medications. During his tenure as FDA commissioner, Scott Gottlieb often spoke about generics as a market force that could help tame climbing drug prices. But such tools only work when companies play fair. A lawsuit is now claiming that … Continue reading “Bio Roundup: Generic Drugs Graft, ASCO Ahead, ElevateBio Rises & More”
ASCO Abstracts: Breast Cancer, Precision Treatments in the Spotlight
The world’s biggest annual cancer conference is just around the corner. Data presented at the American Society of Clinical Oncology meeting each year can change medical practice and make or break companies whose drugs are under the microscope. That’s what makes even the “abstracts,” or snippets of data revealed a few weeks before the meeting, … Continue reading “ASCO Abstracts: Breast Cancer, Precision Treatments in the Spotlight”
Endpoint Security Company CrowdStrike Files Publicly for IPO
CrowdStrike, the cybersecurity company that identified the two Russian government-linked hacker groups that invaded the Democratic National Committee (DNC)’s network during the 2016 presidential campaign, filed publicly for an initial public offering on Tuesday. Sunnyvale, CA-based CrowdStrike sells cloud-based security software and related services by subscription to businesses. Founded in 2011, the company adapted traditional … Continue reading “Endpoint Security Company CrowdStrike Files Publicly for IPO”
Roundup: Strata Oncology, Genomenon, Gilbert Family Foundation, More
Spring is always a busy time for Michigan’s innovation community, so let’s catch up on recent tech and entrepreneurial news below: —Last year, we reported on the Gilbert Family Foundation, a charitable organization founded by Quicken Loans chairman Dan Gilbert and his wife Jennifer, and its initiative to develop gene therapy treatments for neurofibromatosis 1 (NF1). … Continue reading “Roundup: Strata Oncology, Genomenon, Gilbert Family Foundation, More”
Milestones of Innovation 17: ‘Golden Spike’ Heralds Era of Cheap Steel
One hundred fifty years ago May 10, around mid-day, railroad promoters from two coasts clumsily drove the final spikes of America’s first transcontinental railroad near Promontory Point, Utah. Two of the spikes used that day were made of gold. The blows themselves triggered a telegraphic message to the world. The joining of the Central Pacific … Continue reading “Milestones of Innovation 17: ‘Golden Spike’ Heralds Era of Cheap Steel”
ClassDojo CEO: Never Too Early for Kids to Learn About Mindfulness
If you felt a positive disturbance in The Force today, it may have been due to ClassDojo’s Mindful Moment. At 11am local time, millions of kids from schools in 180 countries are participating in the “world’s biggest virtual mindfulness class.” The course comes with a downloadable lesson plan from ClassDojo, a San Francisco-based educational technology … Continue reading “ClassDojo CEO: Never Too Early for Kids to Learn About Mindfulness”
Tech Ethics, Regulation & Strategy: Here’s the Napa Summit Agenda
With Uber’s long-awaited IPO, Facebook’s mounting controversies, and ongoing debates over drug pricing and safety issues, come a great responsibility. A big story in the innovation community now is about the ethics and regulation of tech and life sciences. What are the right ways to safeguard the public, hold corporations accountable, and maintain economic growth? … Continue reading “Tech Ethics, Regulation & Strategy: Here’s the Napa Summit Agenda”
Bio Roundup: Rare Disease Showdowns, Prices on TV, Dealmania & More
The market for drugs for rare or “orphan” diseases continues to grow. An April report from Evaluate Pharma predicted sales of orphan drugs to rise 12 percent a year between now and 2024, when they will account for an estimated 20 percent of worldwide prescription drug sales. The field has gotten so competitive that multiple … Continue reading “Bio Roundup: Rare Disease Showdowns, Prices on TV, Dealmania & More”
Why Investors Are Turning to the Midwest—and How to Keep them Coming
For decades, venture capital investors have targeted the East and West coasts to find and fund their next big startup growth company. The result? Two thirds of VC deals and dollars are currently, as of the first quarter of 2019, held in three states—California, New York, and Massachusetts—in three regions of the U.S. Trailing those … Continue reading “Why Investors Are Turning to the Midwest—and How to Keep them Coming”
Uber Completes $8.1B Public Market Debut in Spite of Tumultuous Past
[Updated 5/10/19, 5 pm ET. See below.] Ride-hailing giant Uber secured $8.1 billion in new capital late Thursday as it priced an initial public offering that set its market capitalization at $82.4 billion, according to calculations by The New York Times and other news outlets. Uber announced late Thursday it will sell 180 million shares … Continue reading “Uber Completes $8.1B Public Market Debut in Spite of Tumultuous Past”
Two Days, Five Biotech IPOs, and $359M Raised for Clinical Trials
It will be hard to top last year’s flurry of biotech companies joining the public markets, but this week is shaping up to be the busiest for life science IPOs in recent memory. Five biotechs priced their IPOs and at least one more is coming. According to IPO research firm Renaissance Capital, 47 IPOs have … Continue reading “Two Days, Five Biotech IPOs, and $359M Raised for Clinical Trials”
Mobility News: Cruise’s New Cash, Tesla’s Pivot to Robotaxis & More
As the mobility industry waits with baited breath to see how Uber’s IPO will play out on Friday, there is plenty of news being made elsewhere in the sector. Cruise scored another massive investment, Toyota AI Ventures opened a new fund, scooters continue to rev up, and more. Read on for details. —Our own Bernadette … Continue reading “Mobility News: Cruise’s New Cash, Tesla’s Pivot to Robotaxis & More”
Lyft Posts $1.1B Loss for Q1 in First Earnings Report Post-IPO
Newly public ride-hailing company Lyft (NASDAQ: [[ticker:LYFT]]) filed its first-quarter earnings results Tuesday, reporting a 95 percent increase in revenue compared with the same period in 2018, but a net loss of nearly $1.14 billion. That first-quarter loss includes $894 million of stock-based compensation and other expenses triggered by the completion of Lyft’s IPO on April … Continue reading “Lyft Posts $1.1B Loss for Q1 in First Earnings Report Post-IPO”
SMA, Migraine Data Lead Neuro Highlights from AAN Meeting
The American Academy of Neurology meeting in Philadelphia is rolling on through the end of this week. There has been plenty of news to digest already. New clinical data could herald cutting-edge treatments for migraine, the rare disease spinal muscular atrophy, the deadly neurological disorder amyotrophic lateral sclerosis, and more. Xconomy previewed the conference last … Continue reading “SMA, Migraine Data Lead Neuro Highlights from AAN Meeting”
Linux Foundation’s Open Source Automotive Software Project Takes Off
When we last covered the Linux Foundation’s Automotive Grade Linux (AGL) project—a collaborative, cross-industry, nonprofit effort to develop a common, open-source software stack for the connected car—it was 2016 and the automotive industry was just beginning to warm up to development partnerships that could advance autonomous vehicles and other mobility services. Three years later, and … Continue reading “Linux Foundation’s Open Source Automotive Software Project Takes Off”
We Did It In Detroit, And So Can You: Fundraising Lessons Learned
As the co-founder of Assembler Labs, a Detroit-based startup studio, I breathed a big sigh of relief after we closed our inaugural round of fundraising at the end of March. It took about seven months of investor meetings, sending around documents, and wrangling signatures, but my co-founder and I looked forward to calmer calendars and … Continue reading “We Did It In Detroit, And So Can You: Fundraising Lessons Learned”
Gener8tor, Motown Team to Launch Summer Music Accelerators in Detroit
Name a genre of music and there’s probably a Detroiter who innovated it. Punk rock? Death, Iggy Pop, and the MC5. Hip-hop? J Dilla. Techno? The Belleville Three. Blues? John Lee Hooker. Rock? The White Stripes. Gospel? Aretha Franklin. And, of course, where would modern R&B and pop be without Motown? Detroit has always been … Continue reading “Gener8tor, Motown Team to Launch Summer Music Accelerators in Detroit”
Bio Roundup: Head and Spine Previews, Biogen Moves, IPO Dreams & More
America continues to suffer from healthcare headaches. Our convoluted private-public insurance system was under scrutiny this week from Democrats, holding a “Medicare for All” hearing in the House, and from Republicans, as several GOP-led states and the Trump administration asked a federal court to sweep away Obamacare. Several companies also want to reduce headaches. This … Continue reading “Bio Roundup: Head and Spine Previews, Biogen Moves, IPO Dreams & More”
At Big Neuro Meeting, Migraine Drug Competitors to Make Oral Arguments
The first new class of migraine drugs in decades won FDA approval last year. But the companies who commercialized these new therapies and their potential competitors are already planning new, more convenient versions, taken as pills instead of injectoins just below the skin, and they will present key data in the next few days at … Continue reading “At Big Neuro Meeting, Migraine Drug Competitors to Make Oral Arguments”
Beyond Meat’s IPO Bags $241M to Make Plant-Based Burgers Mainstream
A Beyond Meat burger is coming to a location near you—and soon. The food technology company’s upsized IPO has raised $241 million to finance plans to bring its plant-based “meat” to more grocery stores and restaurants across the country. Beyond Meat priced its IPO Wednesday evening at $25 per share, which was the high end … Continue reading “Beyond Meat’s IPO Bags $241M to Make Plant-Based Burgers Mainstream”
SMA Moment: Will Gene Therapy Shift Treatment, Costs of Muscle Disease?
This is a big moment for people diagnosed with spinal muscular atrophy, or SMA, a rare and potentially lethal genetic disorder that destroys muscles. For decades, there was no way to change the trajectory of their disease. They now have one marketed medicine, and this month, chances are they’ll have another: a gene therapy that … Continue reading “SMA Moment: Will Gene Therapy Shift Treatment, Costs of Muscle Disease?”
Sight Machine Raises $29M to Connect Dots of Manufacturing Enterprises
When it comes to manufacturing, production and quality is everything. Systems to monitor manufacturing have been around for decades, but they aren’t always complete, sometimes only overseeing specific machines or locations. That’s a problem that Sight Machine aims to address with its software that analyzes the manufacturing process. Its technology uses artificial intelligence, machine learning, … Continue reading “Sight Machine Raises $29M to Connect Dots of Manufacturing Enterprises”
Retailers, Startups Work to Offer Efficient E-Commerce Delivery
The on-demand delivery war in retail is on. In its quarterly earnings call Thursday, Amazon (NASDAQ: [[ticker:AMZN]]) announced it would switch to one-day shipping for Prime members, halving the time the 100 million-plus people who subscribe to the service must wait before receiving their purchases. The Seattle e-commerce giant told analysts the move would cost around … Continue reading “Retailers, Startups Work to Offer Efficient E-Commerce Delivery”
New Zagster CEO on Bike, Scooter Fleets: Don’t Rock the Boat
For transportation veteran Dan Grossman, the “move fast and break things” startup ethos has never really translated to the micro-mobility world of app-enabled motorized scooters and bike sharing. Grossman last week took the helm of Zagster, a startup that sets up and runs micro-mobility programs for towns, cities, colleges, and businesses. The company launches programs … Continue reading “New Zagster CEO on Bike, Scooter Fleets: Don’t Rock the Boat”
Ford, Lincoln Owners Can Get Amazon Packages Delivered to Their Cars
Many of us know that anxious feeling that comes when Amazon texts a notification that it has delivered your package, except you’re nowhere near home at the time to receive it. The mind races: is the package sitting out in plain view for would-be thieves to notice? Will it be destroyed by a passing downpour? … Continue reading “Ford, Lincoln Owners Can Get Amazon Packages Delivered to Their Cars”
Another $568M, and a $7B Valuation, for Automation Firm UiPath
UiPath, which helps businesses automate tedious digital processes such as billing and inventory control, announced today it raised $568 million from investors who agreed on a $7 billion valuation for the company. New York-based UiPath is one of the automation software companies that have been raking in capital recently as they compete for enterprise customers … Continue reading “Another $568M, and a $7B Valuation, for Automation Firm UiPath”
Finding Your Startup Lawyer: What Every Entrepreneur Should Know
Successful management of any new enterprise, regardless of industry, is a process demanding of concerted effort to realize opportunity with a finite set of resources. As an entrepreneur, perfecting your vision, securing and managing funds, building a team, marketing and selling, and executing on plan, all while navigating unexpected obstacles, likely occupy your every day. … Continue reading “Finding Your Startup Lawyer: What Every Entrepreneur Should Know”
Bio Roundup: Biogen’s Strategy, Drug Price Convo, NASH News & More
The road to every new drug approval is littered with the remains of earlier failures. Biopharmaceutical companies don’t like to talk about the failures. But it’s earnings season now, so some of them don’t have much choice. Biogen’s (NASDAQ: [[ticker:BIIB]]) earnings call this week was the first since its Alzheimer’s drug aducanumab failed in a Phase … Continue reading “Bio Roundup: Biogen’s Strategy, Drug Price Convo, NASH News & More”
To Help Boost Female-led Startups, More Women Join Investor Ranks
Houston—Men have long leveraged their networks to succeed in business, and the tech industry has been no exception. Women, finding themselves outside of the club, are now creating their own networks to do the same. Katelyn O’Shaughnessy already had a solid track record, selling TripScope, a travel startup she co-founded in 2013, to Travefy two … Continue reading “To Help Boost Female-led Startups, More Women Join Investor Ranks”
Announcing Net@50: The Roots and Future of the Internet
The first short message went out over Arpanet, the precursor to the internet, 50 years ago this year—and it changed everything. Much of the change has been wonderful—as the internet has revolutionized communication, commerce, and access to information, in the process transforming and improving the lives of billions of people. But as we are ever … Continue reading “Announcing Net@50: The Roots and Future of the Internet”
Midwest Growth Capital Symposium to Feature VC University Seminar
Later next month, the Midwest Growth Capital Symposium (MGCS) will kick off its 38th annual two-day event dedicated to showcasingthe region’s high-growth companies to a cadre of local and out-of-town investors. During the symposium, 32 companies actively seeking funding will pitch to an audience of more than 500 attendees. There will also be a tech … Continue reading “Midwest Growth Capital Symposium to Feature VC University Seminar”
Join Xconomy for Our 8th Annual Napa Summit, June 13-14
Google. Amazon. Genentech. Those are some of the companies you’ll hear from at this year’s Napa Summit, the Xconomy Retreat on Technology, Jobs, and Growth. This is our most special event of the year—the eighth year we’ve held it—and it’s limited to about 100 VIP guests. We’ll tackle big trends, challenges, and opportunities in areas … Continue reading “Join Xconomy for Our 8th Annual Napa Summit, June 13-14”
SPECIAL REPORT: 2019 Blockchain Outlook — Reality Check
After a breakout year in 2017, the blockchain sector suffered a series of blows in 2018, from crashing cryptocurrency prices to increased regulatory scrutiny of crypto ventures and deepening skepticism about whether the technology was actually useful. Now, the industry has entered a crucial phase where blockchain developers need to overcome the limitations of the … Continue reading “SPECIAL REPORT: 2019 Blockchain Outlook — Reality Check”
Can We Afford to Be Cured? A Conversation With ICER’s Steve Pearson
[Corrected, 4/23/19, 7:10 p.m. See below.] New cell and gene therapies bring the possibility of cures once hardly imaginable. But the potential cures could also cost millions of dollars, like Novartis (NYSE: [[ticker:NVS]]), the owner of the gene therapy Zolgensma, has suggested in advance of an imminent FDA approval decision. As public backlash against high … Continue reading “Can We Afford to Be Cured? A Conversation With ICER’s Steve Pearson”
Aptiv Expands Driverless Car Testing, Opens Chinese Mobility Center
Aptiv, a global automotive technology company, announced last week that it has opened a new innovation hub in China—the fastest growing front in the self-driving tech wars. The new entity is called the China Autonomous Mobility Center, and as a result of the move, Shanghai joins Aptiv’s roster of driverless car testing locations, which also … Continue reading “Aptiv Expands Driverless Car Testing, Opens Chinese Mobility Center”