The top biopharma story of the week involves the fast-moving field of lung cancer, which, as we’ve written previously, has several key trials reading out in 2018. A big domino fell this week: data from a two-drug immunotherapy combination developed by Bristol-Myers Squibb. But the results, touted as positive, left more questions than answers. First, … Continue reading “Bio Roundup: Lung Cancer Questions, Migraine Races, HIV Battle & More”
Category: Indiana
Teva Migraine Drug Likely Delayed by Manufacturing Trouble
Teva Pharmaceutical’s bid to bring a new migraine drug to the market faces a possible delay due to manufacturing problems found with one of the company’s partners, and observers are skeptical about whether Teva will be able to get it over the finish line. The FDA was set to issue a decision about Teva’s (NYSE: … Continue reading “Teva Migraine Drug Likely Delayed by Manufacturing Trouble”
Instant Gratification: Whole Foods, Target Offer Same-Day Delivery
[Updated 2/8/18, 1:39 pm.] The race is on to sign up consumers seeking same-day delivery of groceries, household items, and personal goods. Late on Wednesday, Amazon (NASDAQ: [[ticker:AMZN]]) announced it has started free two-hour delivery of products from Whole Foods Market, the most significant example of the e-commerce giant using technology at the Austin, TX-based … Continue reading “Instant Gratification: Whole Foods, Target Offer Same-Day Delivery”
Big Car-Auction Firm KAR Buys SF Mobility Support Startup Stratim
With an eye toward a greater role in the future of mobility services, the big Indiana used-car auction company KAR announced Wednesday it acquired Stratim, a software startup that organizes maintenance and repairs for car-sharing fleets. Carmel, IN-based KAR (NYSE: [[ticker:KAR]]) says Stratim not only augments its core auction business, but also bolsters its advances … Continue reading “Big Car-Auction Firm KAR Buys SF Mobility Support Startup Stratim”
IU Health Expands Precision Genomics Program for Cancer Patients
When Gwen Brack was a junior in college, she was diagnosed with stage IV rectal cancer. She sought treatment, but the cancer soon returned and then spread to her liver and bladder. She underwent rounds of chemotherapy and nine surgeries, but the cancer kept growing. Eventually, she was referred to Indiana University Health’s precision genomics … Continue reading “IU Health Expands Precision Genomics Program for Cancer Patients”
Medical and Patient Groups Warn Congress Against “Right to Try”
Dozens of medical organizations and patient advocacy groups are pushing back against so-called “right-to-try” legislation that passed the Senate in August and is now under consideration in the House. An open letter sent today to House leaders is the latest opposition to the Republican-led push to give desperate patients access to experimental drugs without FDA … Continue reading “Medical and Patient Groups Warn Congress Against “Right to Try””
Walmart Brings Virtual Reality to Retail With Purchase of Spatialand
Walmart’s tech incubator in Silicon Valley, Store No 8, has acquired Spatialand, a virtual reality software firm, as its third portfolio company. While much of the focus in using VR has been on gaming and entertainment, “virtual reality has the potential to reinvent the consumer experience—with an experience we call contextual commerce,” according to a … Continue reading “Walmart Brings Virtual Reality to Retail With Purchase of Spatialand”
As Migraine Races Heat Up, Allergan Touts New Data for Headache Pill
The push to treat migraines with a new class of medicines took another turn on Tuesday when Allergan presented clinical data for an experimental pill meant to help fend off the debilitating headaches after they start. Allergan’s (NASDAQ: [[ticker:AGN]]) ubrogepant, met its main goals in the first of two Phase 3 studies. In a trial … Continue reading “As Migraine Races Heat Up, Allergan Touts New Data for Headache Pill”
Pay It Forward: Capital Drives Bio Innovation in San Diego & Beyond
After starting Organovo in 2007, I spent much of the next decade as CEO seeking financing to advance our bioprinting technology. Because I stepped out of an operational role early last year, I am now in a position of providing financing to aspiring life sciences entrepreneurs. The change has caused me to reflect a bit … Continue reading “Pay It Forward: Capital Drives Bio Innovation in San Diego & Beyond”
E-Commerce Firm Dearduck Uses A.I. in the Hunt for the Perfect Gift
Houston—Knowledge is power, but too much of a good thing can render data meaningless. That’s the struggle many retailers have in an age of data analytics. Think about the retailer e-mails we receive daily or the ads that appear on Google or our social media sites. Though based on our Web searches, those ads don’t … Continue reading “E-Commerce Firm Dearduck Uses A.I. in the Hunt for the Perfect Gift”
Entrepreneurs Look to Angels and Micro-VCs for Cash
You don’t need me to tell you it’s a rough world out there for startups. Venture capitalists have been unusually stingy lately, hanging on to billions of dollars they’d typically be channeling into promising young companies. When those investors do open their wallets, they’re shunning risky investments in favor of what the Wall Street Journal … Continue reading “Entrepreneurs Look to Angels and Micro-VCs for Cash”
Bio Roundup: Wilson’s Warning, Amazon’s Health Biz, Moderna Cash & More
The State of the Union address was…. long. At one hour and 20 minutes, President Trump fell about 9 minutes shy of the high mark. But those who stayed tuned in heard comments about several health policy matters. The president credited the FDA for a record number of generic drug approvals in 2017, which PwC … Continue reading “Bio Roundup: Wilson’s Warning, Amazon’s Health Biz, Moderna Cash & More”
Xconomy Bookclub: “Inferior” Peruses Science’s Historic #MeToo Bias
In his now infamous memo, ex-Google engineer James Damore cited scientific evidence to illustrate why women may not be suited for jobs at some of today’s leading tech companies. Women, he argued, are biologically more attuned to “people” jobs rather than “thing” jobs, like those in technology. But what Damore was doing, others pointed out, … Continue reading “Xconomy Bookclub: “Inferior” Peruses Science’s Historic #MeToo Bias”
Look Out, Investors: Cryptocurrency Values Slide As Warnings Take Off
Bitcoin and other cryptocurrencies have seen dramatic but volatile price surges during the past year. But this month their billions in estimated market value are eroding, amid widening suspicions against one trading platform, a half-billion-dollar heist from another exchange, and an awakened global regulatory community. Warnings are on the rise from regulators, researchers, banking executives—and … Continue reading “Look Out, Investors: Cryptocurrency Values Slide As Warnings Take Off”
Bessemer Makes First Indiana Investment, Leads Zylo’s $9.3M Series A
When Indianapolis-based cloud software company Zylo was making the rounds in the Bay Area last year, talking to potential investors, the company kept hearing that it should meet with Silicon Valley firm Bessemer Venture Partners. Bessemer had never backed an Indiana tech company before but the meetings must have gone well, because Zylo has announced … Continue reading “Bessemer Makes First Indiana Investment, Leads Zylo’s $9.3M Series A”
As A.I. Takes Off, We Need a Plan to Deal with Societal Disruption
As an Xconomist, I have been asked to predict what technology might really take off in 2018. My response is something of a “cheat” in that it relates to artificial intelligence (AI), a technology that has been poised to take off next year for the past several decades and a topic about which I have … Continue reading “As A.I. Takes Off, We Need a Plan to Deal with Societal Disruption”
Your Smart City Is Stupid
Cities have been called a repository of possibilities. What they haven’t been called, at least until recently, is smart. These days, however, the term “smart city” is everywhere, pimped by tech giants like IBM, Google, and Cisco, and embraced by various mayors, city managers, and chief innovation officers from Silicon Valley to Rio to Dubai. … Continue reading “Your Smart City Is Stupid”
After Paper Shakes Sector, Gene Therapy Leader Jim Wilson Talks Safety
[Updated, 1/31/18, see below] Gene therapy pioneer James Wilson and University of Pennsylvania colleagues sounded an alarm Tuesday morning about the use of gene therapy to treat severe diseases like spinal muscular atrophy and Duchenne muscular dystrophy, sending a chill across the sector. Shares of several companies inched downward as word spread about the UPenn … Continue reading “After Paper Shakes Sector, Gene Therapy Leader Jim Wilson Talks Safety”
Evicted from the Smart City: No Citizens Needed
Tech vendors know when they knock on the doors of local politicians to pitch smart cities technologies and promising billions in savings, they are going to find a receptive audience. Big Tech promises what politicians desperately want to hear: that we can address deep-seated, structural urban problems through business-led technological innovation and somehow sidestep the … Continue reading “Evicted from the Smart City: No Citizens Needed”
Building a Smart City Upon a Hill
In my Los Angeles neighborhood there is a gnarly 5-way stop. It’s all stop signs, and because of the number of accidents, the city is considering switching to traffic lights. I receive letters from the street department giving me updates and inviting me to comment. There have been multiple neighborhood meetings. Officials have gone a … Continue reading “Building a Smart City Upon a Hill”
Here’s What I Made (Finally) With My Glowforge Laser Cutter
When I lifted the lid on the Glowforge laser cutter to reveal the family portrait engraved on a wooden jigsaw puzzle, it brought a smile to my face like few other tech products I’ve used before. This simple project—enabled by a very complex machine—was a long time coming, but it was worth the wait. I … Continue reading “Here’s What I Made (Finally) With My Glowforge Laser Cutter”
Bio Roundup: Spark v. ICER, A Solid Revelation, T Cell Deals & More
The United States has a new Health and Human Services chief who is expected to weigh in on the country’s drug-pricing debate. But how Alex Azar, a former pharma executive at Eli Lilly (NYSE: [[ticker:LLY]]), plans to throw his weight around remains to be seen. One of the latest exhibits in the debate is an … Continue reading “Bio Roundup: Spark v. ICER, A Solid Revelation, T Cell Deals & More”
Security Is Dead, Long Live Security
Roughly every three years, someone steps up and boldly claims the security software industry is going away, and they are probably right—much like there is a strong chance of the cold energy death of the universe. However, neither is likely tomorrow. With all due respect, such claims usually suffer from the recency bias or, put … Continue reading “Security Is Dead, Long Live Security”
SoftBank Continues Funding Spree, Leads $865M Round for Katerra
Katerra, a building construction startup inspired by the efficient practices of electronics manufacturing, announced today it has raised $865 million in a Series D fundraising round led by the SoftBank Vision Fund. The company was co-founded in 2015 by Michael Marks, the former CEO of contract electronics manufacturer Flextronics. Katerra has large-scale ambitions that match the … Continue reading “SoftBank Continues Funding Spree, Leads $865M Round for Katerra”
Health Analytics Firm Springbuk Closes $20M Round, Plans Hiring Spree
It’s been a great month for the Indianapolis innovation community. Indiana’s capital city made the list of 20 municipal finalists vying to become the location of Amazon’s second headquarters, and a spate of local tech startups have hit new milestones. One of those startups, Springbuk, announced last week that it has raised $20 million in … Continue reading “Health Analytics Firm Springbuk Closes $20M Round, Plans Hiring Spree”
Should Startups Extend the Window to Exercise Options?
Pinterest did it. Square did it. And Coinbase did it, too. These unicorns have all given departing employees more than the standard 90 days to exercise their stock options. They’ve extended the window to exercise options for employees who have at least a minimum period of service. The tech recruiting site Triplebyte urged an even … Continue reading “Should Startups Extend the Window to Exercise Options?”
Facebook Touts Countermeasures to Election Hacking: Are They Enough?
Facebook expanded its mea culpa on Monday for failing to prevent “bad actors” such as Russian entities from using the social media platform to distort democratic processes—notably the U.S. presidential election in 2016. The company unveiled another series of measures it’s taking to prevent malefactors, who hide behind false names, from spreading fake and incendiary … Continue reading “Facebook Touts Countermeasures to Election Hacking: Are They Enough?”
Hey Alexa, What’s in a Name? Actually, Let’s Call You Amazon
With “Hey Google” and “Alexa” echoing from the expo halls of Las Vegas to millions of homes, the hype around voice-controlled computing is reaching a new peak in early 2018. Voice-controlled devices are permeating our world, and this new user interface is the future of computing—or so we are told by the companies purveying it. … Continue reading “Hey Alexa, What’s in a Name? Actually, Let’s Call You Amazon”
Cargo Zooms Ahead with New Cash, Plans to Expand to 10 Cities
Score one for mobile convenience stores. Cargo, a New York City-based graduate of the Techstars Mobility accelerator, announced Monday it has raised more money from investors, reached its one millionth passenger, and will soon expand from test markets in New York, Chicago, and Boston to new cities . We caught up with Cargo founder and … Continue reading “Cargo Zooms Ahead with New Cash, Plans to Expand to 10 Cities”
Why Spark and Watchdog ICER Don’t See Eye-to-Eye on $850K Gene Therapy
The first gene therapy approved in the U.S. costs $850,000. Announcing the price on Jan. 3, its owner Spark Therapeutics held out the possibility of some relief, such as installment payments, or slim rebates if the drug, a one-time shot into each eye to reduce or reverse inherited vision loss, doesn’t work or wears off. … Continue reading “Why Spark and Watchdog ICER Don’t See Eye-to-Eye on $850K Gene Therapy”
Democratization of Automation: The Next Generation of Industrial Robotics
In the coming years, artificial intelligence will have many transformative impacts, but the one perhaps most resembling science fiction will be the rise of autonomous physical systems: real-world systems that can make decisions for themselves. Of these autonomous systems, self-driving cars have captured the most attention. But the field of manufacturing, which represents one-sixth of … Continue reading “Democratization of Automation: The Next Generation of Industrial Robotics”
Q&A: Dell Med’s DeSalvo Talks Social Health Startups, Data Ownership
Karen DeSalvo has experience working in the public sector, but she’s hardly what you’d call a government bureaucrat. DeSalvo, who is trained as a physician, served as the National Coordinator for Health Information Technology from 2014 to 2016 under President Barack Obama. During some of the time she headed the ONC, as the office is … Continue reading “Q&A: Dell Med’s DeSalvo Talks Social Health Startups, Data Ownership”
UTA Using Robots, Shakespeare to Study Ways to Address Loneliness
Dallas—In healthcare, robots are being created to help with tasks like disinfecting hospital rooms or alerting patients when it’s time to take medications. A study at the Emotional Robotics Living Lab at the University of Texas at Arlington is even exploring how human-robot connection can help fight depression. “We are looking at robots that would be … Continue reading “UTA Using Robots, Shakespeare to Study Ways to Address Loneliness”
Bio Roundup: Spark’s Road Ahead, Juno Rumors, Merck’s Big Day & More
The most overblown health story of the week was President Trump’s health exam. America learned Trump is in perfect health and has “great genes.” He takes Propecia. He doesn’t have heart problems, had a perfect cognitive test score, and is one pound shy of obese. This scintillating information led to a new social media phenomenon, the … Continue reading “Bio Roundup: Spark’s Road Ahead, Juno Rumors, Merck’s Big Day & More”
Tougher “Immigration” Policies On Foreign Tech Crossing U.S. Border
It’s not only people from other countries that are struggling harder to get into the United States these days, it seems. Technology from foreign nations may also be subject to stricter “immigration” rules. The national origins of tech devices and services wasn’t a front-burner question—at least for the general public—until the issue came up at … Continue reading “Tougher “Immigration” Policies On Foreign Tech Crossing U.S. Border”
IU Spinout CyUtil Helps VR Developers Create More Immersive Products
Imagine you’re a world history teacher in rural Indiana who wants to give students the chance to tour the great pyramids of Egypt—feeling the sun’s warmth on their faces and smelling the aromatic spices used to cook the food eaten by pharaohs—without leaving the state. Thanks to virtual reality technology being developed by Indiana University … Continue reading “IU Spinout CyUtil Helps VR Developers Create More Immersive Products”
Absences, Surprises in Amazon’s Final List of 20 Cities for HQ2
And then there were 20. Amazon has winnowed down the field of 238 submissions from communities around North America vying to host a second headquarters (HQ2) of the Seattle-based tech giant. Most large cities with existing or emerging tech hubs appear on the list, from Austin, TX, and Boston, MA, to Washington, DC, and Toronto, … Continue reading “Absences, Surprises in Amazon’s Final List of 20 Cities for HQ2”
In “Age of Amazon,” All Retailers Are Tech Companies, Even Walmart
Technology took center stage this week as the nation’s retailers made their annual pilgrimage to New York. At the National Retail Federation’s three-day conference, which ended Tuesday, the discussion centered on both the disruptive effects and potential promise of e-commerce technologies. Kate Ancketill, the CEO of GDR Creative Intelligence, a retail trends consultancy, said retailers … Continue reading “In “Age of Amazon,” All Retailers Are Tech Companies, Even Walmart”
Three Takes on How Tech Can Rebuild Trust in 2018
Rounding out our series of perspectives and prognostications for the new year, we asked people in Xconomy’s network about trust in the tech industry. Specifically, if you think public perception about the tech industry took a turn for the worse in 2017, what should the industry do to rebuild trust in 2018? Here are responses … Continue reading “Three Takes on How Tech Can Rebuild Trust in 2018”
Google Launches a MOOC to Train Entry-Level IT Support Staffers
Big tech companies like Google are facing heat for developing disruptive technologies that can make traditional jobs obsolete. But at the same time, the tech industry is growing fast, and is eager to recruit workers outside the sector to fill entry-level jobs that often go begging, a Google executive says. Google is betting on online … Continue reading “Google Launches a MOOC to Train Entry-Level IT Support Staffers”
A.I. Could Be Double-Edged Sword for Cybersecurity Industry in 2018
It’s no secret that artificial intelligence is becoming increasingly influential in cybersecurity—on both sides of the battlefield. And while it’s no secret, it should also be no surprise. Although, in many ways, A.I. is still in its infancy, with nearly every industry investing in the space and many companies already benefiting from automation and business … Continue reading “A.I. Could Be Double-Edged Sword for Cybersecurity Industry in 2018”
Why Human Extinction Needs a Marketing Department
Experts at Oxford University and elsewhere have estimated that the risk of a global human extinction event this century—or at least of an event that wipes out 10 percent or more of the world’s population— is around 1 in 10. The most probable culprits sending us the way of the dinosaur are mostly anthropogenic risks, … Continue reading “Why Human Extinction Needs a Marketing Department”
SkySpecs Snags $8M to Expand Drone-Powered Turbine Inspection Service
Drone startup SkySpecs announced this week that it has raised an $8 million Series B funding round. The investment in the Ann Arbor, MI-based company was co-led by Germany’s Statkraft Ventures, the Capital Midwest Fund, and UL Ventures, and also included contributions from returning investors such as Huron River Ventures and Venture Investors. A lot … Continue reading “SkySpecs Snags $8M to Expand Drone-Powered Turbine Inspection Service”
Spark CEO Marrazzo on Gene Therapy Pricing & Paving the Way for the Field
[Updated, 1/13/17, 11:15 a.m. ET] After decades of research and scientific ups and downs, the first U.S. gene therapy, a single, long-lasting treatment called voretigene neparvovec (Luxturna) for rare, inherited blindness, is now on the market. But the commercial challenge facing its developer, Spark Therapeutics, is daunting. Can Spark lead the way in showing that … Continue reading “Spark CEO Marrazzo on Gene Therapy Pricing & Paving the Way for the Field”
Bio Roundup: #JPM18, Axovant’s Fall, CRISPR Caveat, Impact M&A & More
Have you gotten your flu shot yet this year? This winter’s flu season is shaping up to be a particularly nasty one and the Centers for Disease Control and Prevention this week upped its tally of states reporting widespread flu activity to 46. Flu awareness was top of mind at the J.P. Morgan Healthcare Conference … Continue reading “Bio Roundup: #JPM18, Axovant’s Fall, CRISPR Caveat, Impact M&A & More”
E-Commerce Firm Black Rifle Coffee Has Expansion in Its Sights
There wasn’t a lot that Evan Hafer could control on his half-dozen deployments to Iraq and Afghanistan as a Green Beret and CIA contractor. But the one thing he could do something about was the terrible coffee. “I started roasting my own coffee and taking it with me overseas,” he says. “I set up a … Continue reading “E-Commerce Firm Black Rifle Coffee Has Expansion in Its Sights”
Notes From the JPM ’18 Vortex: Gene Therapy’s Reckoning and Lonely Cabs
The annual J.P. Morgan Healthcare conference in San Francisco winds down today, meaning the remaining stragglers are either presenting to half-empty rooms or headed back to colder climes. Compared to a 2017 full of scientific milestones—FDA approvals of gene and cell therapies, a clinical victory for RNA interference, and more—the meeting itself was rather dull. … Continue reading “Notes From the JPM ’18 Vortex: Gene Therapy’s Reckoning and Lonely Cabs”
Loving LTE or Tossing the Smartphone: Tech Leaders Share New Habits
We asked people around the Xconomy network whether their personal patterns of technology usage changed much in response to something that happened in 2017, as part of our series of perspectives and predictions marking the start of a new year. Here are answers from Ben Gilbert, co-founder of Pioneer Square Labs in Seattle and interim … Continue reading “Loving LTE or Tossing the Smartphone: Tech Leaders Share New Habits”
Blockchain and Cryptocurrencies: ScaleVP Comments From the Sidelines
Just because an investor isn’t putting money into blockchain technologies or cryptocurrencies yet, it doesn’t mean they’re not watching these emerging phenomena with interest. Andy Vitus, a partner at Silicon Valley venture capital firm Scale Venture Partners, has been keeping his eye on the potential uses of the blockchain, which is best known as the … Continue reading “Blockchain and Cryptocurrencies: ScaleVP Comments From the Sidelines”
Beyond the Demo: 2018 Could Be Year for Longer, Profitable VR Content
René Pinnell says he and his wife Selena Pinnell were “blown away” by the virtual reality projects their friends were creating in 2014, so they looked for an entrepreneurial niche that would allow them to support such artists. That year the couple, both trained in design, founded a startup in San Francisco, then called KaleidoscopeVR. … Continue reading “Beyond the Demo: 2018 Could Be Year for Longer, Profitable VR Content”