In the wake of the Equifax breach and the global WannaCry ransomware outbreak earlier this year, tensions around cybersecurity are running high. According to a recent study conducted by the Ponemon Institute and sponsored by Barkly, seven out of 10 organizations are reporting their security risk has significantly increased during the past 12 months. Only … Continue reading ““Responsive” Machine Learning Could Lessen Cybersecurity Tradeoffs”
Category: Indiana
Drug Prices, Industry Ties Take Spotlight at HHS Nominee Azar Hearing
If Wednesday’s hearing for Health and Human Services Secretary Nominee Alex Azar is any indication, reining in drug prices and insurance premiums are the policy priorities that will guide Congress’s interaction with the department under a new leader. For the better part of the three-hour hearing by the Senate’s Health, Education, Labor and Pensions committee, … Continue reading “Drug Prices, Industry Ties Take Spotlight at HHS Nominee Azar Hearing”
With Good Data From Rival Migraine Drugs, Doctors Foresee Price Headaches
Amgen (NASDAQ: [[ticker:AMGN]]) and Teva Pharmaceutical (NYSE: [[ticker:TEVA]]) this afternoon are providing the most detailed look yet at two drugs in an emerging class of medicines meant to prevent migraine headaches, rather than just quell their symptoms. While the data for the two drugs, called erenumab (Aimovig, from Amgen and partner Novartis) and fremanezumab (from … Continue reading “With Good Data From Rival Migraine Drugs, Doctors Foresee Price Headaches”
Joining Trend, WI Creates New Business Entity: Benefit Corporations
On Monday, Wisconsin enacted legislation allowing companies to incorporate as benefit corporations. Although this may sound like routine, small-time legislative business, it is just as significant as major policy initiatives being debated in the halls of Congress. On issues from net neutrality to workers’ rights, corporations are perceived to—and often do—engage in practices that maximize … Continue reading “Joining Trend, WI Creates New Business Entity: Benefit Corporations”
Stratim CEO Sees Future with Costly Driverless Cars, but Low Ride Fares
Like many tech entrepreneurs, Sean Behr had a young business that was popular with consumers, but was also losing money. So in February of 2016, he decided to refocus his San Francisco startup on the small, but unexpectedly profitable aspect of his service that could operate in the black. That pivot put Behr in a … Continue reading “Stratim CEO Sees Future with Costly Driverless Cars, but Low Ride Fares”
Bio Roundup: ICER Eyes Cost, Azar at HHS, Gates’s ALZ Cash & More
In our roundup this week, Alzheimer’s disease is in the news, thanks to billionaire Bill Gates and his personal pledge of $100 million toward R&D. That could equal the amount one startup hopes to raise in an IPO to develop drugs for Alzheimer’s and other brain diseases. If a treatment became available, could our health … Continue reading “Bio Roundup: ICER Eyes Cost, Azar at HHS, Gates’s ALZ Cash & More”
After Quadrupling in Size, Lessonly Raises $8M Series B
Lessonly, the Indianapolis-based startup focused on team training software, this week announced it has raised an $8 million Series B funding round. Led by Boston’s OpenView Partners, the round also drew contributions from Rethink Education, High Alpha Capital, and Allos Ventures. Max Yoder, Lessonly CEO and co-founder, says the company has quadrupled in size over … Continue reading “After Quadrupling in Size, Lessonly Raises $8M Series B”
Self-Driving Stampede: Why Mobility Startup Prices Keep Going Up
When automotive supplier Delphi forked over approximately $450 million to buy Boston-based software startup NuTonomy last month, it was the latest in a spate of high-dollar acquisitions involving companies that develop self-driving technologies. NuTonomy, founded by MIT researchers, was only four years old and had raised $16 million in a Series A round the previous … Continue reading “Self-Driving Stampede: Why Mobility Startup Prices Keep Going Up”
Poshmark Picks Up $87.5M to Power the Social, Digital Wardrobe
Poshmark, a social media e-retail company, has raised $87.5 million in a Series D investment round led by Singapore sovereign wealth fund Temasek. That brings the total funding raised by the Redwood City, CA-based company to $160 million. Other investors in the firm include Mayfield, Menlo Ventures, GGV Capital, Inventus Capital, SoftTech VC, Union Grove … Continue reading “Poshmark Picks Up $87.5M to Power the Social, Digital Wardrobe”
DFJ Co-Founder Jurvetson Exits Firm Amid Harassment Charges
[Updated 11/15/17, 11:10 am. See below.] One of Silicon Valley’s most prominent venture capital firm founders has joined the list of VCs who departed from their positions this year in the wake of sexual harassment allegations. Steve Jurvetson, co-founder of Draper Fisher Jurvetson (DFJ), confirmed via a Twitter post Monday that he has left the … Continue reading “DFJ Co-Founder Jurvetson Exits Firm Amid Harassment Charges”
Milestones of Innovation 14: The Biggest Damn Firecracker I Ever Saw
At exactly 7 a.m. on Nov. 9, 1967, the roof of the press viewing stand at Cape Canaveral began shaking from what was happening more than three miles from us. The sky seemed to be cracking as a gleaming 363-foot tall rocket began pushing up from Launch Pad 39 and eastward over the Atlantic. As … Continue reading “Milestones of Innovation 14: The Biggest Damn Firecracker I Ever Saw”
Bio Roundup: Barron Joins GSK, Sage Bounces Back, Valeant Dumps Addyi
Call it a week of second chances. Multiple biotechs breathed new life into drugs sorely in need of it. Sage Therapeutics proved a drug that had failed a trial a rare form of epilepsy could be the first ever approved therapy for postpartum depression. Otonomy, reviving a hearing loss drug thought to be on the … Continue reading “Bio Roundup: Barron Joins GSK, Sage Bounces Back, Valeant Dumps Addyi”
What Sean Parker Shares with Einstein and the Labradoodle’s Inventor
Sean Parker, Facebook’s first president, just joined a group that’s a favorite topic of history listicles: He’s an innovator who has become abashed by the breakthrough he helped to create. Parker, in an interview with Axios on Wednesday, said Facebook’s founders consciously exploited “a vulnerability in human psychology,” by luring users into an addictive engagement … Continue reading “What Sean Parker Shares with Einstein and the Labradoodle’s Inventor”
Cheddar Is on a Mission to Help Software Developers Monetize Faster
It’s a tale as old as tech startups: A software developer creates a new app that she’s convinced will take the world by storm. The only problem? She has no idea how to monetize her brilliant creation. A startup based in Bloomington, IN, called Cheddar aims to solve that problem by changing the way developers … Continue reading “Cheddar Is on a Mission to Help Software Developers Monetize Faster”
Microsoft’s Strategy for Finding What’s Next in Healthcare A.I.
[Updated 11/10/17, 10:25 a.m. See below.] Microsoft is applying the same model it used to launch its quantum computing and chatbot efforts to innovation in healthcare, signaling the company’s ambition and optimism about the transformative potential of artificial intelligence technologies in this enormous endeavor. Peter Lee is the Microsoft Research executive in charge of the … Continue reading “Microsoft’s Strategy for Finding What’s Next in Healthcare A.I.”
Is Your Company Independent or Co-Dependent?
Steve Jobs was once famously quoted stating, “the secret of my success is that we have gone to exceptional lengths to hire the best people in the world.” Employees are a critical part of any company’s backbone, no matter the size or industry of the business. They are the driving force that executes the company … Continue reading “Is Your Company Independent or Co-Dependent?”
Indiana’s Open Data Hub Allows Public to Address State’s Challenges
Municipalities and state governments tend to generate reams of data pertaining to their residents. However, trying to peel back the layers of bureaucratic red tape to reveal something meaningful from government datasets has been a longstanding challenge throughout the country. Government IT departments are often hampered by outdated technology and cumbersome chains of command, but … Continue reading “Indiana’s Open Data Hub Allows Public to Address State’s Challenges”
Biotech Roundup: Opioid News, ASH Preview, Boston Bio IPOs & More
The rising death toll from opioids has prompted policymakers to try various ways to take on the problem. President Trump’s opioid commission released its final report this week, calling for expansion of drug courts, better physician training, and penalties for insurers that don’t cover treatment. But the commission did not say how much its recommendations … Continue reading “Biotech Roundup: Opioid News, ASH Preview, Boston Bio IPOs & More”
Congress Urges Tech Firms to Control Content—But With Qualms
At Congressional hearings this week on Russia’s use of social media to interfere with the 2016 U.S. election, lawmakers pressed Facebook, Twitter, and Google to take exhaustive measures to stop the same thing from happening again. Lawmakers urged the companies to scour their networks to root out foreign advertisers, trolls, and bots; to eliminate messages … Continue reading “Congress Urges Tech Firms to Control Content—But With Qualms”
Spero, Allena Nab $152M As Bio IPOs, With Insider Help, Continue Roll
Two biotechs, Spero Therapeutics and Allena Therapeutics, are headed for the Nasdaq this morning at valuations they’d been aiming for. Their stock offerings are the latest sign of the health of the biotech IPO market, and the willingness of insiders to make sure these deals succeed. Spero, of Cambridge, MA, raised $77 million late Wednesday … Continue reading “Spero, Allena Nab $152M As Bio IPOs, With Insider Help, Continue Roll”
Few Opioid Alternatives In Sight as Crisis Gains Political Attention
As opioid-related deaths skyrocket across the U.S., momentum to combat the epidemic has been mounting in Washington. But the crisis has also highlighted a glaring problem that no amount of politics or policymaking will solve soon: The lack of non-addictive pain medicines. “What is disappointing over the last half-century is that we haven’t really created … Continue reading “Few Opioid Alternatives In Sight as Crisis Gains Political Attention”
ASH Sneak Peeks: Novartis, Juno Update CAR-T Lymphoma Competition
[Corrected, 11/1/17, 5:20 p.m. ET. See below.] The annual American Society of Hematology meeting is next month. But previews of the big data presentations are out today, yielding more insight into what promises to be the first major competition in CAR-T cell therapy: Treatments for people with non-Hodgkin lymphoma (NHL) who have run out of … Continue reading “ASH Sneak Peeks: Novartis, Juno Update CAR-T Lymphoma Competition”
As Facebook Fights Fake News, LeCun Sees Bigger Role for A.I.
As top lawyers from Facebook, Google, and Twitter testify on Capitol Hill this week about Russians using their platforms to interfere in the 2016 U.S. presidential election, it’s becoming clearer that the fight against the spread of fake news won’t be won by humans alone. That’s according to Yann LeCun, a machine learning expert and … Continue reading “As Facebook Fights Fake News, LeCun Sees Bigger Role for A.I.”
New Survey Highlights “Lethargic Pace” of Healthcare Gender Equity
To close the healthcare and life sciences gender gap, there have been programs to move women into the boardroom. People are building mentoring networks. And there have been public pledges to do better. But women in the industry aren’t optimistic about big changes coming soon, according to a new report and survey from digital healthcare … Continue reading “New Survey Highlights “Lethargic Pace” of Healthcare Gender Equity”
As Russians Hacked U.S. Election, Did Big Tech Firms Break Any Laws?
News is constantly streaming out these days about the role of Facebook, Twitter, and Google in the 2016 presidential election; most disturbing to the public is the apparent use of social media, search, and video channels by Russian operatives seeking to influence U.S. voters. Critical lawmakers have blasted the big tech companies for failing to … Continue reading “As Russians Hacked U.S. Election, Did Big Tech Firms Break Any Laws?”
South Bend Code School Helps Get Underserved Kids on Career Path
A few years ago, Alexandra Liggins was a student at Notre Dame studying English and taking pre-med courses. When she began tutoring local high school students in South Bend, IN, she was disheartened by the number of kids who believed that if they weren’t on the path to college, they didn’t have many future job … Continue reading “South Bend Code School Helps Get Underserved Kids on Career Path”
Bio Roundup: CBO’s Praise, Celgene’s Shock, Trump’s Opioid Plan & More
The White House and the FDA turned the spotlight on the nation’s opioid crisis. Blockbuster drugs from Alexion and Tesaro gained expanded approvals, but bad earnings news from Celgene and Biogen brought stocks down. Academics in the U.S. and China made progress with the gene editing technology CRISPR. And as the week’s biggest biotech deal … Continue reading “Bio Roundup: CBO’s Praise, Celgene’s Shock, Trump’s Opioid Plan & More”
As Drugs Fail, Some Researchers Urge a Return to Alzheimer’s Roots
As the quest to find treatments for Alzheimer’s disease keeps crashing against rocks, a group of researchers in the field want their peers to pay more attention to the part of the brain where Alzheimer’s disease first wreaks havoc. A new paper from the researchers, published this month in the journal Alzheimer’s & Dementia, is … Continue reading “As Drugs Fail, Some Researchers Urge a Return to Alzheimer’s Roots”
Cord Cutting: How to Get High-Speed Internet Without Cable, 2017 Edition
Hey folks. If you’re thinking about breaking away from the cable monopolies and getting your data, music, and video in other ways, congratulations, I’m with you. I cut the cord back in 2009, and now millions of people are doing the same every year. With the growing interest in cord-cutting, you’d think it would be … Continue reading “Cord Cutting: How to Get High-Speed Internet Without Cable, 2017 Edition”
Delphi to Buy NuTonomy for $400M+ as Driverless Car Tie-ups Continue
Another big move today in the race to develop self-driving cars: Delphi Automotive has inked a deal to acquire NuTonomy, an autonomous vehicle software startup, for up to $450 million. The U.K.-based automotive supplier (NYSE: [[ticker:DLPH]]) will pay $400 million up front to acquire Boston-based NuTonomy, plus earn-outs of about $50 million, according to a … Continue reading “Delphi to Buy NuTonomy for $400M+ as Driverless Car Tie-ups Continue”
After Natural Disasters, Bluelock Helps Companies Recover Their Data
When hurricanes and other natural disasters strike, buildings and other physical structures aren’t the only things at risk of being destroyed. Crucial data and IT infrastructure can also be lost as a result of inclement weather, and a sector called “disaster-recovery-as-a-service” (DRaaS) has emerged, along with new cloud-based tools, to help mitigate the damage. Indianapolis-based … Continue reading “After Natural Disasters, Bluelock Helps Companies Recover Their Data”
Bio Roundup: Kite’s CAR-T Approved, Obamacare Fix & Lilly mRNA Deal
Kite Pharma wasn’t expecting a regulatory decision for its non-Hodgkin lymphoma treatment until November, but this week, the company got the FDA’s O.K. The approval of axicabtagene ciloleucel (Yescarta) marks the second time in the two months that the FDA has given the nod to a CAR-T therapy, a treatment made from a patient’s own … Continue reading “Bio Roundup: Kite’s CAR-T Approved, Obamacare Fix & Lilly mRNA Deal”
Level Playing Field? How Big Company Dominance May Hinder Innovation
The conventional wisdom about Silicon Valley is that it’s a playground for the underdogs, a fertile ground for young entrepreneurs building startups that are going to “change the world.” Instead, the Bay Area—while, yes, still home to thirsty young entrepreneurs—is increasingly the stomping grounds of a few major tech companies that have come to dominate … Continue reading “Level Playing Field? How Big Company Dominance May Hinder Innovation”
With Pitches for HQ2 Made, Cities Wait on Amazon’s 2018 Decision
From Portland to Pittsburgh, it’s likely that every city in the U.S. with more than 1 million people has made its case to Amazon to locate the company’s second headquarters there. At least, hopefully they have already, because today—if you haven’t heard—was the deadline to apply. Amazon sent North America into a frenzy after announcing … Continue reading “With Pitches for HQ2 Made, Cities Wait on Amazon’s 2018 Decision”
Lab Focused on Human-Centered Design Moves to Put San Diego on Map
For Michèle Morris, the big question hanging over organizers as they laid the groundwork last year for the first Design Forward Summit was whether the innovation community in San Diego understood the value of design. “We didn’t know who was going to show up—and 600 people showed up,” said Morris, who is associate director of … Continue reading “Lab Focused on Human-Centered Design Moves to Put San Diego on Map”
At Lambeau Field, Case & Vance Plot a Path for Emerging Startup Hubs
Green Bay, WI, is among the smallest of the 30-plus cities Steve Case and other leaders of his venture capital firm Revolution have visited since 2014 as part of its national “Rise of the Rest” tour, but Case nonetheless said he sees some of the seeds that could help sprout a cluster of high-tech businesses … Continue reading “At Lambeau Field, Case & Vance Plot a Path for Emerging Startup Hubs”
Kite Nabs First Adult CAR-T Approval With Notable Uptick Of Cures
For the second time in two months, remarkable recoveries from desperate cases of cancer have led to early approval of a cutting-edge therapy called CAR-T, which is made from a patient’s own genetically engineered cells. More than a month before the decision was due, the FDA has given the nod to axicabtagene ciloleucel, now branded … Continue reading “Kite Nabs First Adult CAR-T Approval With Notable Uptick Of Cures”
Eli Lilly to Pursue mRNA Cancer Vaccines with CureVac Pact
[Updated, 10/19/17, 3:17 pm. See below.] Eli Lilly is getting a foothold in messenger RNA (mRNA) cancer vaccines through a deal with CureVac that could develop up to five new therapies. Indianapolis-based Lilly (NYSE: [[ticker:LLY]]) will pay CureVac, headquarted in Germany, $50 million up front, plus make an equity investment in the company valued at … Continue reading “Eli Lilly to Pursue mRNA Cancer Vaccines with CureVac Pact”
After Trump Sounds Off, Senate Has Adult Conversation on Drug Prices
In advance of an anticipated Senate hearing on drug prices, President Donald Trump once again denounced drug companies as “getting away with murder.” The first time he did so, using the same phrase just before his inauguration, the markets shuddered. He also said at the time that “we’re going to start bidding,” a reference to … Continue reading “After Trump Sounds Off, Senate Has Adult Conversation on Drug Prices”
250ok Raises $2.6M Series A, Plans to Expand E-mail Management Tech
E-mail is ubiquitous to modern corporate life, but despite its popularity, it’s not always an effective way to communicate. Between automated inbox filters that barely work, productivity-killing overload, and suspicious communications sent by malicious actors, e-mail can be a potential minefield without the proper visibility into how it’s functioning. That’s the premise behind Indianapolis-based 250ok, … Continue reading “250ok Raises $2.6M Series A, Plans to Expand E-mail Management Tech”
Vinod Khosla on A.I., Health, and the Future of Working (or Not)
Entrepreneur-turned-venture capitalist Vinod Khosla made big headlines almost six years ago when he wrote a blog post called “Do We Need Doctors or Algorithms?” In it, he said medicine needed to be reinvented and he predicted a new era in which artificial intelligence might replace most of the functions that doctors do now—and do it … Continue reading “Vinod Khosla on A.I., Health, and the Future of Working (or Not)”
Bio Roundup: Light For Spark, California Drug Law, IPO Queue & More
In a year of tragedies across the U.S., natural or otherwise, it seemed this week was California’s turn. Fueled by high winds, low humidity, and ample dry vegetation, fires swept through several towns across the state and, as of this writing, have barely been contained. With our minds on friends and loved ones affected by … Continue reading “Bio Roundup: Light For Spark, California Drug Law, IPO Queue & More”
OrthoPediatrics IPO Raises $52M for Medical Implants and Instruments
OrthoPediatrics is making its stock market debut today in a $52 million IPO that will support the company’s lineup of medical devices developed specifically for children. Warsaw, IN-based OrthoPediatrics priced its offering of 4 million shares at $13 each, the midpoint of its projected $12 to $14 range. Underwriters of the offering have the option … Continue reading “OrthoPediatrics IPO Raises $52M for Medical Implants and Instruments”
Android Founder on VR, Voice & the Future of Human-Machine Collaboration
Within 20 years, computer keyboards will be relegated to the technology dustbin, says Android co-founder Rich Miner. Miner helped shape the smartphone era with Android, a mobile operating system startup that Google acquired in 2005. Android software now powers over 2 billion devices. On Tuesday, Miner spoke at a mobile software developer conference in Boston … Continue reading “Android Founder on VR, Voice & the Future of Human-Machine Collaboration”
FDA To Advisors: What If One-Time Gene Therapy Needs Extra Doses?
In the run-up to a key vote on an experimental gene therapy, the FDA raised no major flags about the drug’s track record but said its long-term effect remains an open question. That question should receive a thorough airing Thursday, when a meeting of FDA outside advisors will weigh a recommendation of the one-shot gene … Continue reading “FDA To Advisors: What If One-Time Gene Therapy Needs Extra Doses?”
Eli Lilly Drug Fails in Lung Cancer, Stalling Oncology Strategy
A cancer drug that Eli Lilly was positioning as a challenger to similar drugs from rivals Pfizer and Novartis has failed a late-stage clinical trial in lung cancer. Indianapolis-based Lilly (NYSE: [[ticker:LLY]]) said Tuesday that its drug, abemaciclib (Verzenio), did not meet the Phase 3 study’s main goal of improving overall survival in patients who … Continue reading “Eli Lilly Drug Fails in Lung Cancer, Stalling Oncology Strategy”
Black Fellowship Students Headed From HBCUs to VC Boardrooms
In mid-October, eleven college students will be flying to California for an opportunity that would be the envy of any Ivy League MBA candidate—they’ll meet the venture capital firm partners who will personally mentor them throughout the school year. The students—all but one are undergraduates—come from campuses in Prairie View, Texas; Tallahassee, Florida; and Nashville, … Continue reading “Black Fellowship Students Headed From HBCUs to VC Boardrooms”
VC Funding Surges in Fewer Deals in Third Quarter, and Top 10 Deals
[Updated 10/11/17, 12:25 am. See below.] “More dollars, fewer deals” has been a prevailing trend in venture funding over the past couple of years, and it was evident again in the three months that ended September 30, according to the latest Venture Monitor report. Venture firms invested $21.5 billion in 1,699 startups nationwide during the … Continue reading “VC Funding Surges in Fewer Deals in Third Quarter, and Top 10 Deals”
Blockchain, Banks & the New Web: Q&A With Ethereum Co-founder Lubin
Ethereum co-founder Joe Lubin is calm and soft-spoken when he shares his vision of how blockchain technology and digital currencies could transform the Internet, the global economy, and many aspects of our daily lives. But what he’s talking about could become a raging tempest, and it’s worth paying attention to—especially given the vast sums of … Continue reading “Blockchain, Banks & the New Web: Q&A With Ethereum Co-founder Lubin”
Steve Case’s Rise of the Rest Shines Spotlight on Emerging Tech Hubs
Steve Case, venture capitalist, author, and co-founder of AOL, is preparing to hit the road this week on his sixth Rise of the Rest tour, where he travels to emerging innovation hubs in search of investment-worthy tech startups and to highlight the growth happening outside of places like Silicon Valley and Boston. In the years … Continue reading “Steve Case’s Rise of the Rest Shines Spotlight on Emerging Tech Hubs”