Indigo Adds $250M as It Expands Reach Into Agricultural Supply Chain

Indigo Ag started as a company focused on microbial agriculture—finding microorganisms to develop into seed coatings intended to boost crop yields. While microbiology remains a focus, CEO David Perry says the startup is positioning itself to take on additional aspects of the agriculture business. Boston-based Indigo is revealing one of the ways it aims to … Continue reading “Indigo Adds $250M as It Expands Reach Into Agricultural Supply Chain”

German Conglomerate Buys OnCourse Learning in Reported $500M Deal

Bertelsmann, a large media and publishing conglomerate headquartered in Germany, said Monday that it has acquired OnCourse Learning, a Brookfield, WI-based provider of online professional training programs. Bertelsmann said Monday in a news release that the amount it’s acquiring OnCouse for is in the “mid-nine-digit euro range,” meaning roughly halfway between €100 million and €1 … Continue reading “German Conglomerate Buys OnCourse Learning in Reported $500M Deal”

Bio Roundup: CRISPR Ruling, “America’s Nobels,” IPOs & More

The long-running patent feud over CRISPR-Cas9 gene editing appears to be over, just as U.S. biotech companies gear up for the first human tests of the landmark technology. This week, a federal appeals court upheld a previous ruling handing a CRISPR-Cas9 patent to the Broad Institute of MIT and Harvard. The decision by the three-judge … Continue reading “Bio Roundup: CRISPR Ruling, “America’s Nobels,” IPOs & More”

With Cornershop, Walmart Expands On-Demand Delivery to Latin America

Walmart is taking the e-commerce delivery business south of the border. The Bentonville, AR, retailer announced Thursday it has acquired Cornershop, an on-demand online service that delivers products from supermarkets, pharmacies, and specialty shops in Mexico and Chile, for $225 million. “We are focused on making life easier for customers and associates by building strong … Continue reading “With Cornershop, Walmart Expands On-Demand Delivery to Latin America”

Living on the Edge: Amazon, AT&T, Packet Pursue “Cloudlet” Computing

The word “cloud”—as in cloud computing, and cloud storage—has served as a handy shorthand term, but it has always been inherently vague and a little misleading. When businesses and consumers use a cloud service provider like Amazon Web Services or Apple’s iCloud, their data, photos, and music don’t get processed in the misty skies above … Continue reading “Living on the Edge: Amazon, AT&T, Packet Pursue “Cloudlet” Computing”

Gilead Partners with Precision Bio in Search of Gene-Editing HBV Cure

Gilead Sciences is turning to gene editing in its effort to develop a cure for hepatitis B virus infections—DNA-cutting enzymes that would eliminate the virus in the body, something current hep B drugs can’t do. Foster City, CA-based Gilead (NASDAQ: [[ticker:GILD]]) is partnering with Precision Biosciences, a company that has used its proprietary gene-editing platform … Continue reading “Gilead Partners with Precision Bio in Search of Gene-Editing HBV Cure”

South Bend Code School Adds Revenue Stream with Code Works Dev Shop

When South Bend Code School launched in 2015, its founders were looking for a way to teach kids career skills that might enable them to find a job without a college degree. As that effort grew and gained popularity, people in the community began reaching out to SBCS seeking software development work. “As we were … Continue reading “South Bend Code School Adds Revenue Stream with Code Works Dev Shop”

Bio Roundup: A Gene Editing 1st, China Rises, Schenkein Steps Away

If you’re still recovering from a Labor Day hangover or busy searching for the identity of the anonymous writer of the anti-Trump op-ed for the New York Times, you may have missed a few biomedical firsts. This week brought the first sliver of human data from an in-body gene editing procedure, and the results were … Continue reading “Bio Roundup: A Gene Editing 1st, China Rises, Schenkein Steps Away”

Bio Roundup: Pfizer’s Rare Results, U.K.’s CAR-T No, IPO Go-Go & More

Before you head out for the final summer getaway, catch up on the week’s headlines. Pfizer upped the ante in the field of transthyretin amyloidosis (ATTR) treatment, where competition to treat the rare disease has grown increasingly complex. We’ll start with what was—and wasn’t—in Pfizer’s data release Monday, top up with more ATTR news, then … Continue reading “Bio Roundup: Pfizer’s Rare Results, U.K.’s CAR-T No, IPO Go-Go & More”

Wireless Internet Firms Take On Big Telecoms in Cities and Suburbs

If you’re a city dweller, and unhappy with the big company that provides your Internet connection, chances are good there’s a scrappy little outfit that thinks it can do better for you. Metropolitan areas have become target territories for the wireless Internet service providers, or WISPs, that for a long time have been the only … Continue reading “Wireless Internet Firms Take On Big Telecoms in Cities and Suburbs”

Rivaling Google, Web-Mining Diffbot Opens Its Knowledge Graph to All

Diffbot, a tech startup that continuously scours the Web to assemble a “knowledge graph” of billions of facts in context, announced today that it’s opening up the searchable resource to the public—with starter rates as low as a cable TV bill. Mountain View, CA-based Diffbot gleans unstructured data scattered across websites, ads, blog posts, videos, … Continue reading “Rivaling Google, Web-Mining Diffbot Opens Its Knowledge Graph to All”

Puls Snags $50M to Grow On-Call Repair Service for Smartphones, IoT

Puls Technologies, whose on-demand technicians repair broken smartphones and install connected home devices, announced today it has raised $50 million to expand its reach as a unified source of device maintenance and consumer support. San Francisco-based Puls, founded in 2015, offers to dispatch technicians quickly to a customer’s home or office to replace malfunctioning parts, … Continue reading “Puls Snags $50M to Grow On-Call Repair Service for Smartphones, IoT”

Duke Spinout Evecxia Appoints John Kaiser CEO

John Kaiser has been appointed CEO of Research Triangle Park, NC-based Evecxia Therapeutics. Kaiser, who has been working with the company since March, was most recently interim CEO of Baltimore-based Cerecor (NASDAQ: [[ticker:CERC]]). His experience also includes positions at Denysias Bioscience, Acadia Pharmaceuticals (NASDAQ: [[ticker:ACAD]]), and Eli Lilly (NYSE: [[ticker:LLY]]). Evecxia, a Duke University spinout, … Continue reading “Duke Spinout Evecxia Appoints John Kaiser CEO”

Bio Roundup: EpiPen Shortage, Bluebird’s Bet, Biotech IPOs & More

It’s back-to-school season and that means it’s time to load up on school supplies. For many students and schools, one crucial item is in high demand but hard to come by: the EpiPen. Some schools stock the epinephrine autoinjectors so they can respond quickly to a student’s allergic reaction to food. Though the autoinjectors are … Continue reading “Bio Roundup: EpiPen Shortage, Bluebird’s Bet, Biotech IPOs & More”

Bluebird Bio Turns to Gritstone’s A.I. to Find TCR Cancer Targets

Bluebird Bio is betting that artificial intelligence technology from Gritstone Oncology can find new targets for cancer drugs, and the companies have struck a partnership to develop multiple cell therapies. Cambridge, MA-based Bluebird (NASDAQ: [[ticker:BLUE]]) develops gene and cell therapies. In cancer, the company focuses on a type of cell therapy called T-cell receptor therapy … Continue reading “Bluebird Bio Turns to Gritstone’s A.I. to Find TCR Cancer Targets”

San Antonio’s Earth Class Mail Buys Digital Receipt Maker Shoeboxed

San Antonio—Earth Class Mail is acquiring Durham, NC-based Shoeboxed, which digitizes physical receipts, for an undisclosed price, the companies planned to announce this morning. Earth Class Mail, which is focused on turning traditional paper mail into digital records, is adding to its product offering by buying Shoeboxed. The 14-year-old San Antonio-based business recently made upgrades to … Continue reading “San Antonio’s Earth Class Mail Buys Digital Receipt Maker Shoeboxed”

Would Uber’s IPO Be a Revival or a Reckoning?

In its early years, Uber was a headstrong force knocking down preconceived ideas about transportation and, along with Lyft, sparking the imaginations of countless entrepreneurs who are now building a new industry called “mobility.” As it closes in on its first decade, Uber is a conundrum: A Silicon Valley unicorn with $7.3 billion in cash, … Continue reading “Would Uber’s IPO Be a Revival or a Reckoning?”

Bio Roundup: Big Approvals, ICER Influence, Drug-Price Pushback & More

[Updated 8/17/18, 10:21 a.m. See below.] We’ll start the roundup this week with two drug approvals that came late last Friday. Both were landmarks for the companies receiving the nod, Alnylam Pharmaceuticals and Amicus Therapeutics. We also saw a new biotech emerge in the muggy New York heat, a couple deals for new flu vaccines, … Continue reading “Bio Roundup: Big Approvals, ICER Influence, Drug-Price Pushback & More”

To Avoid Trouble, Companies Must Support Harassed Employees First

When news breaks about sexual harassment at a company like Uber, the public is likely to believe that the entire business has a cultural problem. In contrast, the same isn’t true for other issues, such as financial misconduct, which the public tends to see as a “bad apple” situation. That’s according to a study released … Continue reading “To Avoid Trouble, Companies Must Support Harassed Employees First”

Ford’s Autonomic Pairs With Alibaba Cloud On Mobility Hub for China

Ford—one of the automakers competing in China’s huge car market—is now making a bid to provide China’s leading software infrastructure hub dedicated to streamlining transportation by connecting cars and riders with mobility services. Ford’s recently acquired unit Autonomic, which co-created the automaker’s Transportation Mobility Cloud (TMC), inked a deal Tuesday to partner with Alibaba Cloud, … Continue reading “Ford’s Autonomic Pairs With Alibaba Cloud On Mobility Hub for China”

Bio Roundup: Medicare Drug Prices, FDA Moves, Gene Therapy News & More

Two imminent FDA rulings on two separate drugs aren’t just noteworthy for the patients they’ll help, but the long and winding road their developers have taken to get to this point. First is Alnylam Pharmaceuticals, which has spent 16 years and over $2 billion to try to bring an unproven form of medicine, RNA interference … Continue reading “Bio Roundup: Medicare Drug Prices, FDA Moves, Gene Therapy News & More”

Austin Group Joins Other Tech Efforts to Promote Responsible AI Use

Artificial intelligence is poised to infiltrate nearly all aspects of human life. Given this development, technologists are focusing on how to ensure the technology usage is governed by ethics. “The general rule is that power begets responsibility,” says Michael Stewart, founder and CEO of Lucid AI, an AI startup in Austin. “If you’re bringing in a … Continue reading “Austin Group Joins Other Tech Efforts to Promote Responsible AI Use”

Lack of Diversity Isn’t a “Pipeline Problem,” It’s a Network Problem

Recently, I was in Chicago for Paradigm IQ’s D&I Lab: Data-Driven Strategies to Attract & Hire Diverse Talent, a one-day workshop designed to equip attendees with new strategies for designing an inclusive organization. In a room full of people with titles like chief people officer, director of diversity and inclusion, and director of leadership and organizational … Continue reading “Lack of Diversity Isn’t a “Pipeline Problem,” It’s a Network Problem”

Blockchain Tomatoes & Edible Peels: Startups Innovate to Fight Spoilage

As much as 40 percent of food in this country is never eaten, yet 41 million people don’t have enough to eat, including 13 million children, according to the Natural Resources Defense Council and the U.S. Department of Agriculture. Some of that food insecurity is due to food spoilage, rendering billions of dollars’ worth of … Continue reading “Blockchain Tomatoes & Edible Peels: Startups Innovate to Fight Spoilage”

The Technology Behind Fighting California’s Fires & Other Disasters

As wildfires continued to burn across the length of California this month, Gov. Jerry Brown urged residents to stay on the alert and warned that the cost of fighting the climate-driven blazes will continue to strain future state budgets. Residents of the three Northern California counties hardest hit by wildfires last year have already learned … Continue reading “The Technology Behind Fighting California’s Fires & Other Disasters”

Bio Roundup: Alnylam’s Moment, Read on Rebates, Skinny Plans & More

Millions of people might be on vacation as we hit the dog days, but drug makers and politicians aren’t taking a break from the gamesmanship over high drug prices. After two years of blowing smoke, the Trump administration is threatening action on a few fronts, including against the powerful middlemen known as PBMs that decide … Continue reading “Bio Roundup: Alnylam’s Moment, Read on Rebates, Skinny Plans & More”

BioDelivery Sciences Names Thomas Smith Chief Medical Officer

BioDelivery Sciences International (NASDAQ: [[ticker:BDSI]]) has appointed Thomas B. Smith to serve as chief medical officer. Smith comes to the Raleigh, NC, drug company from Charleston Laboratories in Jupiter, FL, where he was chief medical officer. His experience also includes executive positions at Ameritox, Mallinckrodt Pharmaceuticals (NYSE: [[ticker:MNK]]), and Covidien. BDSI develops products based on … Continue reading “BioDelivery Sciences Names Thomas Smith Chief Medical Officer”

For Women Only: E-Retail Subscription Firm Athena Club Raises $3.8M

[Updated 7/31/18 7:46 am. The story and headline has been changed to reflect an updated amount.] Athena Club, a subscription program for feminine hygiene products, is the latest entrant into the direct-to-women e-commerce space and announced today that it has raised $3.8 million in funding. Co-founder Maria Markina says her New York-based startup gives women … Continue reading “For Women Only: E-Retail Subscription Firm Athena Club Raises $3.8M”

Bio Roundup: An Alzheimer’s Head-Scratcher, OUTBio, GSK & Gilead Shakeups  

The devil is in the details, and key clinical trial results made that abundantly clear this week. Eisai and partner Biogen released the highly anticipated details of an Alzheimer’s disease study they had already deemed positive, after an initial failure. In one sense, the study was the success they have claimed. A high dose of … Continue reading “Bio Roundup: An Alzheimer’s Head-Scratcher, OUTBio, GSK & Gilead Shakeups  “

OUTBio, a Biopharma LGBTQ Group, Grows Fast & Ponders Its Future

In June, Jennifer Petter, the founder and chief scientific officer of biotech startup Arrakis Therapeutics, got an e-mail from a stranger. His name was Ramsey Johnson, a biotech veteran who works in clinical operations at Boston startup Phoenix Tissue Repair. Johnson was writing about OUTBio, a networking organization for LGBTQ members of the biopharma community. … Continue reading “OUTBio, a Biopharma LGBTQ Group, Grows Fast & Ponders Its Future”

Eisai & Biogen Reveal Promising Alzheimer’s Data, But Questions Linger

Data from six additional months of treatment with an experimental drug for Alzheimer’s disease were enough to turn a failed mid-stage clinical trial into a possible success. On Wednesday, the Japanese pharmaceutical company Eisai and its U.S.-based partner, Biogen, explained how, providing details that point to ways that their drug, unlike many before it, might … Continue reading “Eisai & Biogen Reveal Promising Alzheimer’s Data, But Questions Linger”

SnappyScreen’s Booths Protect People While They Have Fun in the Sun

Applying sunscreen while outdoors is a long-accepted way to help keep our skin safe from sunburn and cancer. Yet the Centers for Disease Control and Prevention says less than a third of women, and even fewer men, report using it when going outside for more than an hour. “You should put it on more frequently … Continue reading “SnappyScreen’s Booths Protect People While They Have Fun in the Sun”

Announcing XCON 2018: A Conference on Technology and Transformation

This fall, we are convening exemplary business leaders, investors, and far-seeing technologists for an in-depth exploration of the innovation ecosystem and its impact on the future. Come join us at our newest interactive conference, XCON: The Xconomy Conference on Technology and Transformation. It spans three days, November 4-6, and three innovation venues in the Boston … Continue reading “Announcing XCON 2018: A Conference on Technology and Transformation”

Bio Roundup: Drug Prices, CRISPR Caveats, Rubius IPO Pop & More

After nearly two years of all smoke, no fire around President Trump’s promise to curtail drug prices, there’s finally some glimmer of action. Pfizer said last week it would halt its price hikes, and Novartis and Merck took similar actions this week. But we still don’t know the details of the administration’s drug-pricing policy, if … Continue reading “Bio Roundup: Drug Prices, CRISPR Caveats, Rubius IPO Pop & More”

If the Shoe Fits: Luxury Shoe Club Launches E-Consignment Store

One in five pairs of shoes sit unworn in the average woman’s closet. So, why not sell these unused, or slightly used, pairs to someone who will wear them? That’s the view of Scott Van Valkenburgh, co-founder of Luxury Shoe Club, a Raleigh, NC-based startup that caters to women who want to buy and sell … Continue reading “If the Shoe Fits: Luxury Shoe Club Launches E-Consignment Store”

E.U. Slaps $5B Antitrust Fine on Google; Trump Blasts Back With Tweet

[Updated 7/19/18, 9:59 am. See below.] If top European leaders faced a testy President Donald Trump in a series of meetings this summer, imagine the mood when the president of the European Commission arrives at the White House next Wednesday. President Trump and the European Union’s top executive officer, Jean-Claude Juncker, are slated to discuss … Continue reading “E.U. Slaps $5B Antitrust Fine on Google; Trump Blasts Back With Tweet”

Inari Agriculture Sprouts with Plans to Gene Edit “Personalized Seeds”

The seeds farmers plant in their fields can carry certain desirable traits, such as drought tolerance or pest resistance. Breeding or genetic engineering can produce such traits, but ag biotech startup Inari Agriculture aims to take trait development to a new level—customizing seeds to grow best in the soil and weather at the farm where … Continue reading “Inari Agriculture Sprouts with Plans to Gene Edit “Personalized Seeds””

Walmart, Microsoft Deepen Partnership as Both Grapple With Amazon

The enemy of my enemy is my friend—even in the retail and cloud computing businesses. So says retail giant Walmart (NYSE: [[ticker:WMT]]) as it announced this morning a five-year partnership with Microsoft (NASDAQ: [[ticker:MSFT]]) to use machine learning and other technologies, deepening an existing partnership between two of Amazon’s biggest rivals. “Whether it’s combined with our … Continue reading “Walmart, Microsoft Deepen Partnership as Both Grapple With Amazon”

Bio Roundup: Pfizer’s Prices, Novartis Cuts, Gene Therapy Guide & More

Drug price changes typically happen either at the start of the calendar year or the beginning of the third quarter. Such changes are routine for many companies, but Pfizer took an unusual step this week by rolling back scheduled price increases on 40 of its drugs. The change of plan happened after Pfizer (NYSE: [[ticker:PFE]]) … Continue reading “Bio Roundup: Pfizer’s Prices, Novartis Cuts, Gene Therapy Guide & More”

With $112M Fund, Glasswing Looks to Drive East Coast A.I. Startups

In a sea of emerging tech venture funds, Glasswing Ventures is trying to stand out. The Boston firm announced today it has closed its debut investment fund at $112 million. That’s bigger than the “micro-VC” funds of the past decade, but much smaller than the mega-funds (often in the billion-dollar range) that have been raised … Continue reading “With $112M Fund, Glasswing Looks to Drive East Coast A.I. Startups”

E-Retail Startup Pointy Raises $12M, Helps Small Shops Be Found Online

Mark Cummins wondered why online search engines could help you locate a landmark halfway around the world in a second but couldn’t tell him whether the corner store had a craft beer he liked. That’s what led him to co-found Pointy, which makes a hardware device that enables small retailers to easily upload inventory onto … Continue reading “E-Retail Startup Pointy Raises $12M, Helps Small Shops Be Found Online”

BioCryst Drops Idera Pharma Merger After Shareholders Veto Deal

BioCryst Pharmaceuticals is ending a plan to merge with Idera Pharmaceuticals and form a single company focused on rare diseases. Durham, NC-based BioCryst (NASDAQ: [[ticker:BCRX]]) terminated the merger agreement on Tuesday following a meeting that saw shareholders vote overwhelmingly against the proposal. Of the more than 80 million shares represented in the vote, 50.6 million … Continue reading “BioCryst Drops Idera Pharma Merger After Shareholders Veto Deal”

Venture Funding Keeps Momentum Amid IPO Wave; Plus Q2’s Top 10 Deals

[Updated 7/12/18, 9:24 am. See below.] Last year, U.S. venture capital investments swelled to a level not seen since the dot-com era of the early 2000s. This year could be even bigger. Investors funneled $57.5 billion into U.S. companies through the first six months of 2018, according to the latest Venture Monitor report produced quarterly … Continue reading “Venture Funding Keeps Momentum Amid IPO Wave; Plus Q2’s Top 10 Deals”

Bio Roundup: Dunsire’s Danish, Price Hikes, Rare-Disease Race & More

[Corrected, 7/6/18, 1:26 pm. See below.] Xconomy was dumbstruck this week, and not by the fireworks overhead. Our friend and one of our earliest employees, San Diego editor Bruce Bigelow, died suddenly last weekend. Bruce covered everything—and everyone—in San Diego’s innovation scene, including the life sciences. Some of our favorite stories of his sprang from … Continue reading “Bio Roundup: Dunsire’s Danish, Price Hikes, Rare-Disease Race & More”

The Empathy Economy: Emotional Intelligence in Customer Service

The “empathy economy” will help define the new reality of human and machine interactions in the customer service industry. A takeoff on the sharing economy, the empathy economy will grow due to brand mania and increased automation in the workplace. Consumers are inundated by brands in their day-to-day lives, and these brands sometimes create personal … Continue reading “The Empathy Economy: Emotional Intelligence in Customer Service”

In Celebration of Bruce Bigelow: Our Memories, His Playlist

[Updated, 7/5/18. See below] Bruce Victor Bigelow, editor of Xconomy San Diego, passed away Friday afternoon, June 29, at the age of 63. He had suddenly fallen ill less than a week earlier, after he returned to San Diego from a hiking trip in Utah. Our initial post about Bruce’s death is here. And the … Continue reading “In Celebration of Bruce Bigelow: Our Memories, His Playlist”

Study: Blood Test for Prostate Cancer Can Guide Therapy, Extend Lives

Blood tests for cancer, known as liquid biopsies, have become available in recent years to guide treatments for people already diagnosed. But how useful are they? A paper published last week in the journal JAMA Oncology makes the case that one such test, Oncotype DX AR-V7 Nucleus Detect, might be worth its $3,980 price tag. … Continue reading “Study: Blood Test for Prostate Cancer Can Guide Therapy, Extend Lives”

Xconomy Mourns the Loss of San Diego Editor Bruce Bigelow

[Updated, 7/5/18. See below] It is with profound sadness that we at Xconomy say goodbye to our longtime friend and editor of Xconomy San Diego, Bruce Bigelow. An outstanding journalist, colleague, and friend, and a fixture of the San Diego innovation scene, Bruce passed away today at age 63 after a brief illness. We are … Continue reading “Xconomy Mourns the Loss of San Diego Editor Bruce Bigelow”