[Updated 5/7/18, 5pm ET. See below.] Genetic testing that helps guide more precise cancer treatment is making its way into standard practice in major U.S. medical centers. Could the same eventually be true for depression? One test maker thinks it has finally gathered enough evidence to convince psychiatrists to order its product and make more … Continue reading “Will New Study Cut Guesswork for Depression Medicine Prescriptions?”
Category: Raleigh-Durham
Venture Firms to New York Wedding Startup Zola: ‘I Do’ to $100M
Most wedding registries are focused on the lead-up to the day of the ceremony. New York startup Zola also sees opportunity in connecting with—and making a sales pitch to—married couples years after they’ve tied the knot. Zola is an “e-commerce business disguised as a wedding company,” said Shan-lyn Ma, the startup’s founder and CEO, in … Continue reading “Venture Firms to New York Wedding Startup Zola: ‘I Do’ to $100M”
Bio Roundup: IDO Fallout, Express Scripts Dumps Amgen, Isaly Out & More
Here’s a case study of how fast things can change in biopharma. For a few years, a type of cancer drug called an IDO inhibitor was all the rage, a promising path to expanding the reach of immunotherapy. Major drug makers were dealing, too. Through acquisitions and alliances, they rolled out a spate of large-scale … Continue reading “Bio Roundup: IDO Fallout, Express Scripts Dumps Amgen, Isaly Out & More”
Cord-Cutting for Kids: Video App Kanopy Adds Free Children’s Shows
If you’ve already liberated yourself from a cable subscription in favor of streaming video services over the Internet, you’re parcelling out your dollars to get the content you want most from services such as Netflix, Hulu, and N.B.A. League Pass. A lesser-known option, Kanopy, offers an unusual streaming subscription deal: Pay nothing, because your university … Continue reading “Cord-Cutting for Kids: Video App Kanopy Adds Free Children’s Shows”
California’s Top Court Sets Tougher New Rules on Hiring “Gig Workers”
California employers who classify their workers as independent contractors will be consulting their lawyers today, says A. Mark Pope, an attorney who helped persuade the state’s highest court to establish sweeping new restrictions on hiring so-called “gig workers.” The California Supreme Court on Monday set new standards that will make it harder for companies in … Continue reading “California’s Top Court Sets Tougher New Rules on Hiring “Gig Workers””
Three Lessons Punk Rock Teaches Us About Being a Business Leader
Inspiration comes in many forms, and as an entrepreneur, I found mine early on in an unusual place: punk rock. There are strong parallels between the business of punk rock and startups. When you’re starting a new business venture, you wear many hats—leader, innovator, developer, marketer, HR rep—with very little budget or certainty. You might … Continue reading “Three Lessons Punk Rock Teaches Us About Being a Business Leader”
Why “Micro-Learning” is the New Diploma For Today’s Jobseekers
You’d be hard-pressed to find a workplace today where using technology isn’t an integral part of the job, whether it’s an AI-powered recruiting tool, special coding software for app development, or even just Google Sheets that help workers keep track of budgets. Whether you’re applying for a position in marketing or in the field of … Continue reading “Why “Micro-Learning” is the New Diploma For Today’s Jobseekers”
City Staffers Share Innovation Insights at Smart Cities Accelerator
In cities across the United States, the benefits of bike-sharing and electric scooters that can be easily rented with a smartphone app have often been overshadowed by controversy. In Dallas, Los Angeles, and Washington, DC, for example, complaints flooded into city offices earlier this year about the proliferation of “dockless” bikes cluttering sidewalks, handicap parking, … Continue reading “City Staffers Share Innovation Insights at Smart Cities Accelerator”
United Therapeutics Reaches $141M Deal for PAH Drug Firm SteadyMed
Drug developer SteadyMed has been building momentum to take on the established seller of a therapy for a rare lung disease. But the rivalry could be over before it even started. Instead of competing against the United Therapeutics line-up of therapies for pulmonary arterial hypertension, SteadyMed’s lead drug is now in line to join them. … Continue reading “United Therapeutics Reaches $141M Deal for PAH Drug Firm SteadyMed”
Diagnostics Developer Nanopore Wins Agtech and Food Startup Showcase
In both humans and farm animals, time is crucial when diagnosing illness. An early diagnosis means treatment can be given before the disease worsens. In some forms of aquaculture, the diagnostic time line stretches out a little longer. Fish farmers need to take a boat to the offshore cages where salmon are raised. Samples are … Continue reading “Diagnostics Developer Nanopore Wins Agtech and Food Startup Showcase”
Bill Gates on Saving Babies, Educating Kids, and Picking a Major
On a sunny spring afternoon, William Henry Gates III strolled into the Harvard University science center. Several hundred students and invited guests were waiting for him in the auditorium. Security was tight, but not overly so (he’s used to it). Gates was there Thursday for a conversation with Frank Doyle, Harvard’s dean of engineering and … Continue reading “Bill Gates on Saving Babies, Educating Kids, and Picking a Major”
Bio Roundup: CRISPR Tests, Parkinson’s Questions, Opioid Bills & More
Politics is more partisan than ever these days, but the opioid crisis might be one of the few issues where elected officials find common ground. This week, members of Congress exercised a bipartisan effort in both chambers to advance dozens of measures proposing various approaches to fighting the opioid epidemic. A Senate committee voted unanimously … Continue reading “Bio Roundup: CRISPR Tests, Parkinson’s Questions, Opioid Bills & More”
DARPA Enlists Insects in R&D Effort to Protect the Food Supply
Farmers spend a lot of time and money trying to keep insects from damaging their crops. But the U.S. military sees some of these bugs as potential friends, not foes. A government-funded research project is studying how to use insects to deliver a targeted therapy to a crop following an outbreak of disease, a disaster, … Continue reading “DARPA Enlists Insects in R&D Effort to Protect the Food Supply”
What President Trump Gets Wrong About Amazon’s Effect on the Economy
For the past week or so, President Trump has been deriding Amazon as a destroyer of jobs and the main reason many retail companies are failing. Unfortunately, this is a very one-sided and uninformed view of how Amazon is changing our economy. I run a retail operation that sells almost exclusively on Amazon. Since its … Continue reading “What President Trump Gets Wrong About Amazon’s Effect on the Economy”
Aspect Venture’s Jennifer Fonstad on Hot Areas of Tech, Diversity, & More
Jennifer Fonstad and Theresia Gouw launched Aspect Ventures with their own money in February 2014—and have hardly looked back. “We closed our first investment that first week,” Fonstad says. The pair went on to make a number of investments that first year before deciding to raise funds more formally from outsiders, like a conventional venture … Continue reading “Aspect Venture’s Jennifer Fonstad on Hot Areas of Tech, Diversity, & More”
Techstars Alexa Firms Address Settings Where Voice Is ‘Most Natural’
Smart speakers are becoming increasingly common in our homes. Users can instruct these devices to order takeout, give the weather forecast, or turn on or off various Internet-connected devices. The Consumer Technology Association estimates that nearly 44 million voice-enabled assistants will be sold this year in the United States. Unit sales rose 279 percent from … Continue reading “Techstars Alexa Firms Address Settings Where Voice Is ‘Most Natural’”
Using Analytics, Fitcode Aims to Connect Shoppers to Jeans That Fit
There are few things more universal in wardrobes the world over than blue jeans. But they are also the number one item that is returned by online shoppers, says Rian Buckley, founder and CEO of Fitcode. “Fit is the number one purchase driver and reason to return,” she says. For many of us, the idea … Continue reading “Using Analytics, Fitcode Aims to Connect Shoppers to Jeans That Fit”
Bio Roundup: Hope for Lungs, Bradner’s Complaint, FDA Nods & More
The biggest news this week was in oncology, hands down. Merck showed that its immunotherapy pembrolizumab (Keytruda) might become a common option for many patients newly diagnosed with advanced lung cancer, but the bigger picture is that the field is moving fast. While pembrolizumab notched the headline-grabbing data, others are also working to develop options … Continue reading “Bio Roundup: Hope for Lungs, Bradner’s Complaint, FDA Nods & More”
Want to Find Stellar Software Engineers in the Midwest? Here’s How
It may seem obvious that companies in the Midwest face challenges attracting and retaining talent, given our weather and location far from the coasts. One need only to look at college football recruiting, after all, to see how the average annual snowfall on campus matters almost as much as last season’s win/loss record. To some … Continue reading “Want to Find Stellar Software Engineers in the Midwest? Here’s How”
Facebook: Lip Service to Privacy Is Over
As publicity-shy Facebook co-founder and CEO Mark Zuckerberg testified before both houses of Congress last week amid an avalanche of criticism about the dearth of user privacy on the world’s biggest social media network, it became crystal clear that the entire social media industry has entered a new and perilous phase. Trust in all social media … Continue reading “Facebook: Lip Service to Privacy Is Over”
Cancer Wrap: Blueprint, Checkmate, More AACR News & Phase 3 Blues
The big headlines from the American Association for Cancer Research meeting in Chicago were all about the battle over the latest lung cancer data, and for good reason. Lung cancer remains the deadliest cancer, but the Phase 3 data suggest that treatment options for some of the direst cases could soon rapidly expand. There were … Continue reading “Cancer Wrap: Blueprint, Checkmate, More AACR News & Phase 3 Blues”
U.S. Funding for Biomedical Research Takes Upturn
At the end of March, Congress passed a $1.3 trillion spending bill to fund federal agencies for the rest of the fiscal year and avert another government shutdown. The 2,232-page legislation included a $3 billion funding increase for the National Institutes of Health (NIH), the second largest in the health agency’s history. Other research and … Continue reading “U.S. Funding for Biomedical Research Takes Upturn”
For More Lung Cancer Patients, the Promise of No Chemo Looms Larger
[Editor’s note: Ben Fidler co-authored this report.] A decade from now, it’s possible that immunotherapy will have made a big dent in lung cancer, which is by far the deadliest type of the disease. Drugs from several companies have worked their way forward, initially for patients who have failed chemotherapy, and now, in some cases, … Continue reading “For More Lung Cancer Patients, the Promise of No Chemo Looms Larger”
Novan Makes Kelly Martin’s CEO Role Permanent
Kelly Martin has been named permanent CEO of Novan (NASDAQ: [[ticker:NOVN]]). The Morrisville, NC-based drug developer appointed Martin interim CEO last June, part of a corporate shakeup in which the company laid off 20 percent of its staff and shifted founding CEO Nathan Stasko to chief scientific officer. Those moves followed the failure of SB204, … Continue reading “Novan Makes Kelly Martin’s CEO Role Permanent”
Bio Roundup: Lung Cancer Showdown, Gene Therapy Deals, IPO Busts
This weekend, cancer immunotherapy will once again take biopharma’s center stage. At one of the year’s big cancer meetings, investors, researchers, and many others will have a close eye on a group of presentations touting new lung cancer regimens that combine immunotherapies with other treatments. The presentations could shift the dynamics of the fast-moving landscape, … Continue reading “Bio Roundup: Lung Cancer Showdown, Gene Therapy Deals, IPO Busts”
No “Pink Tax”: Billie, a Shave Club for Women, Raises $6M
[Corrected, 4/11/18, 4:48 p.m. ET. See below.] Billie, a direct-to-consumer seller of monthly shaving and body care products subscriptions, has raised $6 million in new funding. The New York-based startup, which launched in November, previously raised $2.5 million. This latest round of funding was led by Silverton Partners in Austin and included existing investors Female … Continue reading “No “Pink Tax”: Billie, a Shave Club for Women, Raises $6M”
With New Data, Drug Combos, Lung Cancer Experts Scramble to Keep Pace
When oncologist Renato Martins finished his medical training, advanced lung cancer was almost certainly a quick death sentence. “I knew, by name, every patient who had survived two years,” he says. Thanks in large part to the arrival of cancer immunotherapy, things are much different today. While lung cancer remains by far the leading cause … Continue reading “With New Data, Drug Combos, Lung Cancer Experts Scramble to Keep Pace”
Expectations Rise on Q1 Surge in Venture Funding; and Top 10 Deals
[Updated 4/11/18 10:13 am. See below.] Venture capital investors poured more than $28.2 billion into U.S. companies during the first three months of 2018—marking the strongest single quarter in at least a dozen years, according to the Venture Monitor Report released today by Seattle-based PitchBook and the National Venture Capital Association (NVCA). The $28.2 billion that … Continue reading “Expectations Rise on Q1 Surge in Venture Funding; and Top 10 Deals”
With Alzheimer’s Failure, vTv Fares No Better Than Old Partner Pfizer
When vTv Therapeutics reacquired its ineffective Alzheimer’s drug from Pfizer in 2011, it thought it could produce better results by testing it in a larger group of patients. On Monday, vTv’s gambit proved unsuccessful. Like so many other Alzheimer’s drugs before it, vTv’s azeliragon failed, taking millions of investor dollars with it. It could not … Continue reading “With Alzheimer’s Failure, vTv Fares No Better Than Old Partner Pfizer”
E-Commerce Startups Open Door to Endless Virtual Closet
The sharing economy is moving into our bedroom closets. We already apply this idea to transportation (Uber vs. taxi) and vacation accommodations (Airbnb vs. hotel). Now, thanks to a growing number of e-commerce companies, the ability to share goods and services is being applied to our wardrobes through programs that offer clothing rentals for a … Continue reading “E-Commerce Startups Open Door to Endless Virtual Closet”
Xconomy Roadmap 2018: Top 15 Innovation Areas to Watch
With the first quarter in the books, it’s time to step back and lay out Xconomy’s editorial map for the rest of the year. As readers know, we strive to cover a wide range of innovation sectors, from tech and life sciences to healthcare and education—all with a mix of on-the-ground reporting, daily news stories, … Continue reading “Xconomy Roadmap 2018: Top 15 Innovation Areas to Watch”
Bio Roundup: Ex-Kiters Say Allo, NASH Cash & Data, Alkermes No & More
Happy Friday, everyone. We’ll start this week with biotech deals, one featuring a couple of CAR-T heavyweights who have re-emerged after selling Kite Pharma for $12 billion. They will try to shepherd to market a different type of the promising cancer immunotherapy: allogeneic T cells that come from donors, not from a patient’s own blood. … Continue reading “Bio Roundup: Ex-Kiters Say Allo, NASH Cash & Data, Alkermes No & More”
Cleaner Vehicles Help Make Smarter Cities
Two of the most popular terms in urban planning today are smart cities and clean energy. These concepts naturally go hand-in-hand. As cities get smarter, they use energy more efficiently and in a more controllable fashion, and they are better able to incorporate intermittent clean energy sources. Cities, and the power grids that support them, … Continue reading “Cleaner Vehicles Help Make Smarter Cities”
How Next-Gen Chipmakers Are Raising Money, Taking On Tech Giants
The advent of big fundraising rounds for startup chip innovators—a class shunned by most venture capital firms only a few years ago—seems to mark a turnaround in recent VC attitudes about semiconductor investments. But it turns out VCs weren’t the only driving force behind the change in fundraising prospects for the young companies now inventing … Continue reading “How Next-Gen Chipmakers Are Raising Money, Taking On Tech Giants”
Getting Personal: Retailers Use New Tech to Court Individual Shoppers
“Personalized shopping” has long been the guiding light for retailers. But in the age of Amazon (NASDAQ: [[ticker:AMZN]]), traditional stores have been searching for the best way to digitize what was once a person-to-person process. “Internet shopping is now across mobile and Web, and now, the [question] is, ‘How do we create great experiences for … Continue reading “Getting Personal: Retailers Use New Tech to Court Individual Shoppers”
Bio Roundup: Biotech IPOs, Migraine Progress, Takeda Woos Shire & More
If the recent IPO activity seems to be on overdrive, it’s not your imagination. The number of companies filing to go public in the U.S. in the first quarter was up 44 percent compared to the same period a year ago, according to data compiled by consulting and accounting firm EY. Life science companies accounted … Continue reading “Bio Roundup: Biotech IPOs, Migraine Progress, Takeda Woos Shire & More”
FoodLogiQ Lands $19.5M for Food Safety and Supply Chain Software
For some time, consumers have been demanding that food companies provide more information about the origins and the safety of their food. Soon, regulators will require it. FoodLogiQ has commercialized software that provides details on food as it is harvested or processed, and moved along the supply chain. As new food safety rules loom, the … Continue reading “FoodLogiQ Lands $19.5M for Food Safety and Supply Chain Software”
The Edge or the Cloud? It Depends on the App
There’s no arguing that the cloud has transformed the way organizations deal with data and apps. It has freed IT departments from constantly provisioning and managing storage, while bringing overall costs down. For these reasons and more, companies everywhere are moving more and more data and compute tasks to the cloud every day. It’s important, … Continue reading “The Edge or the Cloud? It Depends on the App”
Among Facebook’s Woes, EU’s Strict Privacy Laws May Loom Largest
In a continuing effort to regain the trust of its disillusioned users, Facebook on Wednesday announced new privacy controls where settings can be made from a central menu, rather than by tunneling through as many as 20 screens. As Facebook unveiled the sweeping revisions, though, it also made a striking admission: The company knew it … Continue reading “Among Facebook’s Woes, EU’s Strict Privacy Laws May Loom Largest”
Going Downhill: Roam Robotics’ Exoskeleton Supports Aging Skiers
Robotics has found its way to the ski slopes. San Francisco-based Roam Robotics has developed an exoskeleton, worn on the legs, that the company says will improve skiers’ endurance and safety while they blaze down trails. For skiers 45 or older, Roam says, the exoskeleton can provide vital support for aging knees that might be … Continue reading “Going Downhill: Roam Robotics’ Exoskeleton Supports Aging Skiers”
Are You Being Deliberate About Diversity in Your Investment Portfolio?
“We looked, but we couldn’t find any companies to acquire led by women or founders of color.” “I want to hire diverse talent, but it’s impossible to find.” “It’s not my fault that the financial sector doesn’t have a more varied talent pool or deals to make with non-white males.” I have heard all of … Continue reading “Are You Being Deliberate About Diversity in Your Investment Portfolio?”
FTC Opens New Probe: Revisits Its Old Charges On Facebook Privacy Practices
Among the host of legal woes Facebook is now confronting amid news about the misuse of its member profiles in election politics: The Federal Trade Commission revealed Monday that it is investigating the social media giant’s privacy practices. The FTC decision comes in the wake of recent reports about the ease with which political consulting … Continue reading “FTC Opens New Probe: Revisits Its Old Charges On Facebook Privacy Practices”
EY Report Suggests Improving Conditions for U.S. IPOs in 2018
U.S. IPO activity has been ticking up, with 36 IPOs raising more than $12.7 billion in the United States so far this year, according to data released Monday by EY, the global consulting and accounting firm. Although there are still several days remaining in the first quarter of 2018, EY reports the number of first-quarter … Continue reading “EY Report Suggests Improving Conditions for U.S. IPOs in 2018”
Ada-AI Seeks to Build a Diverse Artificial Intelligence Community
Artificial intelligence innovation has become part of our everyday lives—retailers use it to tailor the product recommendations they make; biotech companies hope it can create customized medicine. But its shortcomings, born of human biases, are becoming apparent as well. Take, for example, facial recognition technologies that work best on white people and make the most … Continue reading “Ada-AI Seeks to Build a Diverse Artificial Intelligence Community”
Auris Health’s Surgical Robot Gets FDA Green Light for Lung Cancer
Auris Health is now the latest surgical robot company with the go-ahead to enter the U.S. market. The Redwood City, CA, based company, formerly known as Auris Surgical Robots, said Friday that its robotic system has cleared the FDA’s regulatory bar, allowing the system to be used for diagnosing and treating lung cancer tumors. The … Continue reading “Auris Health’s Surgical Robot Gets FDA Green Light for Lung Cancer”
Founders, Pay Attention to This Stuff—Not the Stock Market
The Dow Jones Industrial Average. Nasdaq. Startup exits. Funding rounds. In our 24/7 connected world, there’s no shortage of data you can access, study, and agonize over. The market’s latest move—from boom to correction—has commentators and analysts in a tizzy; many investors are feeling anxious, too. It’s easy to get distracted by all this chatter, … Continue reading “Founders, Pay Attention to This Stuff—Not the Stock Market”
Bio Roundup: CMS Backs Cancer Tests, Right to Try Passes, AbbVie Sinks
We’ll start this week’s roundup with several stories from Washington, DC, that could have a lasting effect on public health. The FDA continued its campaign against cigarettes, while the Centers for Medicare & Medicaid Services (CMS) gave a much-needed boost to the developers of cancer diagnostics. In its omnibus spending bill, Congress set aside more … Continue reading “Bio Roundup: CMS Backs Cancer Tests, Right to Try Passes, AbbVie Sinks”
YouTube Limits Firearms Videos; Gun Rights Group Cries Censorship
YouTube has broadened its restrictions on gun-related videos, while thousands of Americans are mobilizing to demand stricter gun controls Saturday in a mass march spurred by young survivors of a deadly armed attack on a Florida high school last month. Google’s popular video-hosting site will bar videos that facilitate direct sales of firearms or accessories, … Continue reading “YouTube Limits Firearms Videos; Gun Rights Group Cries Censorship”
At Opioid Hearing, BIO Exec Proposes Ways to Boost Pain Drug Development
After months of meetings and Congressional hearings on the unrelenting opioid addiction crisis, Congress has finally responded, with 25 bills that aim to attack the problem from all sides. The House Energy and Commerce Committee began two days of hearings on Wednesday that reviewed the draft legislation that lawmakers want to get to the House … Continue reading “At Opioid Hearing, BIO Exec Proposes Ways to Boost Pain Drug Development”
Hungry for Innovation, Big Food Firms Seek Alliances With Startups
Big Food is getting serious about innovation. Many top food companies are increasingly pumping money into supporting young, innovative startups, according to a recent analysis by CB Insights. The firms include stalwarts like Kraft Heinz (NASDAQ: [[ticker:KHC]]), which has an incubator and accelerator program called Springboard, and relative newcomers like the Greek-style yogurt maker Chobani, … Continue reading “Hungry for Innovation, Big Food Firms Seek Alliances With Startups”