HemaQuest Gets $13M Transfusion in Extension of Series B Financing

San Diego-based HemaQuest Pharmaceuticals, a biotech developing small molecule drugs for treating sickle cell disease and other blood disorders, has gotten another capital transfusion after once again extending its Series B financing. In a statement today, HemaQuest says it has raised an additional $13 million to support a mid-stage trial of the company’s lead drug … Continue reading “HemaQuest Gets $13M Transfusion in Extension of Series B Financing”

Allylix Raises $18.2M for Renewable Production of Aroma Chemicals

[Corrected 3/12/12, 11:35 pm to show total investment of $18.2 million.] Germany’s BASF Venture Capital has invested $13.5 million in a financing round that raised a total of $18.2 million for Allylix, the San Diego-based renewable chemicals startup that uses fermentation technology and genetically engineered yeast to produce specialized flavor and fragrance chemicals. Also participating … Continue reading “Allylix Raises $18.2M for Renewable Production of Aroma Chemicals”

AIDS Drugs Were the Start. Let’s See More FDA Accelerated Approvals

There’s been a lot of talk in biotech lately about the need for reforms at the FDA, to make it run faster and more predictably. One idea is taking shape in a bill starting to move through Congress. And at least at first glance, it looks like it’s based on good common sense. The idea … Continue reading “AIDS Drugs Were the Start. Let’s See More FDA Accelerated Approvals”

Crowdfunding: The Train to the Future Is Leaving—Get on Board

It has been a whirlwind last few days in the crowd-funding world. For those of you who have not yet tuned in to this, there is legislation afoot, backed by the President and (so far) the House, that would enable, in effect, mini- IPOs as a way to fund startups. Forget everything you know about … Continue reading “Crowdfunding: The Train to the Future Is Leaving—Get on Board”

San Diego’s InflammaGen Advances Therapy to Mitigate Effects of Shock

After completing some promising pre-clinical studies, San Diego’s InflammaGen Therapeutics says it is raising additional capital, as it moves to mid-stage trials of an experimental treatment that’s intended to prevent multi-organ failure in patients suffering acute shock. InflammaGen has “almost closed” on a $2.5 million round of Series A financing, according to CEO John Rodenrys. … Continue reading “San Diego’s InflammaGen Advances Therapy to Mitigate Effects of Shock”

Allylix Obtains $18,200,000 New Financing Round

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=a40229c4-9762-49da-9a4c-ab628e8af3e6&Preview=1 Date 3/12/2012 Company Name Allylix Mailing Address 6020 Cornerstone Court West San Diego, CA 92121 Company Description Allylix has developed proprietary technology that allows it to produce a group of natural products called terpenes at low cost. In nature, terpenes are produced by plants in minute quantities to serve a number … Continue reading “Allylix Obtains $18,200,000 New Financing Round”

HemaQuest Pharmaceuticals Obtains $13,000,000 Series B Financing

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=bdba02ff-1aa0-4eb6-b5be-8275108f1f5e&Preview=1 Date 3/12/2012 Company Name HemaQuest Pharmaceuticals Mailing Address 11995 El Camino Real San Diego, CA 92130 Company Description HemaQuest is a company developing proprietary small molecule therapeutics to treat serious blood disorders. Website http://www.hemaquest.com Transaction Type Venture Equity Transaction Amount $13,000,000 Transaction Round Series B Proceeds Purposes Proceeds from the financing … Continue reading “HemaQuest Pharmaceuticals Obtains $13,000,000 Series B Financing”

The Lytro Camera Is Revolutionary, But It’s No iPhone

The inventors and investors behind the Lytro, the hot new “light field” camera that creates refocusable digital photos, are trying to have it both ways. They’re arguing that their new camera, which sells for $399-$499, will revolutionize consumer photography in the near term by freeing people from shutter delays and the need to focus their … Continue reading “The Lytro Camera Is Revolutionary, But It’s No iPhone”

Cebix Obtains $8,799,305 New Financing Round

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=ff88958d-8348-40d4-995a-2bb5d05578a3&Preview=1 Date 3/9/2012 Company Name Cebix Mailing Address 1298 Prospect Street La Jolla, CA 92037 Company Description Cebix is focused on the development of chronic replacement therapy based on human proinsulin C-peptide for the treatment of type 1 diabetic neuropathy. The role of C-peptide will also be explored in type 1 diabetic … Continue reading “Cebix Obtains $8,799,305 New Financing Round”

Triptrotting Secures $1,000,000 Series A Funding

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=67b33b4a-f0f9-463b-845c-7c0f71c824ab&Preview=1 Date 3/9/2012 Company Name Triptrotting Mailing Address 130 West Union St Pasadena, CA 91103 Company Description Welcome to Triptrotting, a global community of world travelers and local hosts (we call them Triptrotters), who are matched together based on compatibility. Watch the video and see what other Triptrotters have to say. Website … Continue reading “Triptrotting Secures $1,000,000 Series A Funding”

NationBuilder Garners $6,250,000 New Financing

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=bb182357-5bcf-49ff-b188-d6a87782b81c&Preview=1 Date 3/9/2012 Company Name NationBuilder Mailing Address Undisclosed Los Angeles, CA 90015 Company Description Introducing the world’s first Community Organizing System. To organize people online, leaders need both a website and a people database, but it’s expensive and hard to connect them together. That’s why we created a Community Organizing System … Continue reading “NationBuilder Garners $6,250,000 New Financing”

San Diego Tech Scene Presents: March Mingle VIII

March Mingle is a technology-agnostic event that brings together software developers of all flavors for San Diego’s annual “Technology Woodstock,” or maybe the “Ultimate Geek Happy Hour.” Mingle is hosted by San Diego Tech Scene without sales or technical presentations, and guests are invited to talk shop, trade war stories, and munch on finger food … Continue reading “San Diego Tech Scene Presents: March Mingle VIII”

Angels Favored Healthcare & Internet, With Bigger Rounds in 2011

Each time new private investing data comes out, it seems like it’s another chance for California to show its dominance. That’s the case with the Halo Report, but this particular report also reveals some interesting trends in angel investing. Put together by the Angel Resource Institute, Silicon Valley Bank, and the data services firm CB Insights, … Continue reading “Angels Favored Healthcare & Internet, With Bigger Rounds in 2011”

San Diego Life Sciences Roundup: Aragon, Illumina, CareFusion, & More

We saw some sizable deals in the life sciences domain over the past week, including an interesting partnership that Domain Associates formed with Moscow-based Rusnano. —The venture capital firm Domain Associates and Moscow-based Rusnano, the government-owned Russian Corporation of nanotechnologies, agreed to jointly invest $760 million on both sides of the globe. Under the deal, … Continue reading “San Diego Life Sciences Roundup: Aragon, Illumina, CareFusion, & More”

An Opportunity for Congress to Vote for Job Creation

Congressional leaders of both parties have a short-term opportunity to come together in rare bipartisan fashion and get on the right side of American economic growth and job creation. With the House expected to pass a bill this week that would temporarily ease regulatory requirements related to young, high growth companies filing for an initial … Continue reading “An Opportunity for Congress to Vote for Job Creation”

Sramana Mitra Combats Infant Entrepreneur Mortality

Investor Stewart Alsop has called San Francisco Xconomist Sramana Mitra “a symbol of everything that is great about America: a geek, an entrepreneur, an immigrant, a leader.” He could have added “prolific writer”: Mitra is the author of a blog and five books, as well as three years’ worth of Forbes columns. Throughout these writings, … Continue reading “Sramana Mitra Combats Infant Entrepreneur Mortality”

Oblong Industries Lands Series B Funding Round

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=f72e9151-8715-4603-a3b6-da361cb8e1c0&Preview=1 Date 3/8/2012 Company Name Oblong Industries Mailing Address 923 E. Third St. Unit 111 Los Angeles, CA 90013 Company Description Oblong is developing gesture-recognition technologies. Website http://www.oblong.com Transaction Type Venture Equity Transaction Amount Undisclosed Transaction Round Series B Proceeds Purposes Oblong and its partners view this latest investment round as an … Continue reading “Oblong Industries Lands Series B Funding Round”

Boston Scientific Acquires Cameron Health for $150,000,000

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=34a932ae-f994-444b-933a-3943f1ab002c&Preview=1 Date 3/8/2012 Company Name Cameron Health Mailing Address 905 Calle Amanecer San Clemente, CA 92673 Company Description Cameron Health, Inc., a development stage medical device company, is creating the next generation of implantable electronic device utilizing state-of-the-art technologies. We are a team of specialized, high technology, creative individuals with decades of … Continue reading “Boston Scientific Acquires Cameron Health for $150,000,000”

The Thinking Behind Domain’s $760M Life Sciences Deal in Russia

The partnership that the life sciences venture firm Domain Associates and the Russian state technology firm Rusnano disclosed yesterday began almost two years ago, at a time when the U.S. financial crisis was especially bleak. Domain partner Brian Dovey says he initially conceived of the alliance as a way to tap a new and substantial … Continue reading “The Thinking Behind Domain’s $760M Life Sciences Deal in Russia”

The Dollar Shave Club Obtains $1,000,000 Series A Financing Round

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=6732a87a-e5a2-4e02-817a-3e05e9d3b749&Preview=1 Date 3/7/2012 Company Name The Dollar Shave Club Mailing Address Undisclosed Los Angeles, CA 90049 Company Description The company offers a monthly subscription service for grooming supplies. Website http://www.dollarshaveclub.com Transaction Type Venture Equity Transaction Amount $1,000,000 Transaction Round Series A Proceeds Purposes Proceeds purposes were not disclosed. M&A Terms Venture Investor … Continue reading “The Dollar Shave Club Obtains $1,000,000 Series A Financing Round”

Sequent Medical Receives $26,000,000 Series C Round

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=88851756-72e4-456c-88fb-fd7993307a53&Preview=1 Date 3/7/2012 Company Name Sequent Medical Mailing Address 11A Columbia Aliso Viejo, CA 92656 Company Description The company is dedicated to the development of innovative devices to advance the endovascular treatment of neurovascular disease conditions. Website http://www.sequentmedical.com Transaction Type Venture Equity Transaction Amount $26,000,000 Transaction Round Series C Proceeds Purposes We … Continue reading “Sequent Medical Receives $26,000,000 Series C Round”

Qualcomm’s Irwin Jacobs Becomes CEO Emeritus, 20 Years After IPO

Qualcomm shareholders gave a standing ovation to Irwin Jacobs, who marked his passage into emeritus status at the San Diego wireless giant’s annual meeting today, 20 years after he convened the company’s first meeting as a public company. Jacobs said in December that he planned to step down from the board at the company he … Continue reading “Qualcomm’s Irwin Jacobs Becomes CEO Emeritus, 20 Years After IPO”

Disease Foundations Play Growing Role in Biotech Business Model

California is home to the largest concentration of biotechnology companies in the world. They are responsible for 27 percent of the nation’s biomedical pipeline and they received $2.6 billion in venture capital investment in 2011, by far the largest sum for any state. For the first time ever, California’s life sciences companies will have a … Continue reading “Disease Foundations Play Growing Role in Biotech Business Model”

San Diego’s Aragon Raises $42 Million, Targets Hormone-Driven Cancers

Aragon Pharmaceuticals, a San Diego startup targeting hormone-driven cancers, has raised $42 million in a Series C financing led by a new investor, the Topspin Fund, a Long Island, NY-based firm affiliated with the hedge fund Renaissance Technologies. Aragon CEO Richard Heyman tells me the life sciences startup was founded in 2009 to advance work … Continue reading “San Diego’s Aragon Raises $42 Million, Targets Hormone-Driven Cancers”

Nasty Gal Secures $9,000,000 New Round

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=9579f2e8-9714-4d05-b238-9e7738ea1476&Preview=1 Date 3/6/2012 Company Name Nasty Gal Mailing Address 523 W. 6th Street Los Angeles, CA 90027 Company Description Nasty Gal is a global online destination for fashion-forward, free-thinking girls. In 2006, founder Sophia Amoruso started an eBay store selling a highly curated selection of vintage pieces. In just five short years, … Continue reading “Nasty Gal Secures $9,000,000 New Round”

Aragon Pharmaceuticals Obtains $42,000,000 Series C Financing Round

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=f44304db-9839-48df-b3c0-da8dc9787003&Preview=1 Date 3/6/2012 Company Name Aragon Pharmaceuticals Mailing Address 12780 El Camino Real San Diego, CA 92130 Company Description Aragon Pharmaceuticals is a San Diego based biopharmaceutical company focused on developing a pipeline of new anti-endocrine therapies targeting the biology of hormone resistant cancers. Website http://www.aragonpharmaceuticals.com Transaction Type Venture Equity Transaction Amount … Continue reading “Aragon Pharmaceuticals Obtains $42,000,000 Series C Financing Round”

SignNow Lands $2,000,000 Series A Financing

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=baf0806f-e3ed-4f04-b409-f31c0bc640e9&Preview=1 Date 3/6/2012 Company Name SignNow Mailing Address 2901 W Coast Hwy. Newport Beach, CA 92663 Company Description SignNow, Inc. is a company startup seeking to bring the millennia-old practice of using hardcopy signatures into the digital age through user-friendly, consumer-oriented Web applications. Website http://www.signnow.com Transaction Type Venture Equity Transaction Amount $2,000,000 … Continue reading “SignNow Lands $2,000,000 Series A Financing”

Connotate Acquires Fetch Technologies for Undisclosed Sum

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=03b38140-5737-46f7-91bb-34db2b81bc88&Preview=1 Date 3/6/2012 Company Name Fetch Technologies Mailing Address 841 Apollo St. El Segundo, CA 90245 Company Description Fetch Technologies enables organizations to access, aggregate and use real-time information from websites. Fetch’s enterprise solution is tailored to fit each customer’s needs and navigate websites to instantly deliver meaningful, useful and usable data … Continue reading “Connotate Acquires Fetch Technologies for Undisclosed Sum”

Connect Bestows ‘Hall of Fame’ Award on Hybritech Founder Ted Greene

Biotech pioneer Ted Greene was a little teary-eyed when he stepped to the lectern last week to acknowledge his role as the founder of a San Diego biomedical diagnostics startup called Hybritech—and the parade of life sciences companies that followed. “I would like to thank the wonderful people who joined me on the wonderful adventures … Continue reading “Connect Bestows ‘Hall of Fame’ Award on Hybritech Founder Ted Greene”

Five Reasons Illumina Should Fight Roche’s Insulting Low-Ball Bid

Illumina is like the Apple of the genomics business. Tools made by the San Diego company (NASDAQ: [[ticker:ILMN]]) are revered by genomics researchers around the world just like millions of consumers love their iPhones and iPads. And Illumina holds its dominant position at an enviable moment in history, as we’re heading into a scientific golden … Continue reading “Five Reasons Illumina Should Fight Roche’s Insulting Low-Ball Bid”

Digital Doctoring: Lowering the Cost of Healthcare Through Innovation

Connect and the West Wireless Health Institute have organized this presentation as a Frontiers in Science and Technology lecture. Dr. Joseph Smith, the institute’s chief medical and science officer, has been invited to discuss efforts to create an affordable and connected healthcare system. More information and online registration is here.

The 10th SABPA Science & Technology Forum: Frontiers in Oncology

The annual Science & Technology Forum organized by the Sino-American Biomedical and Pharmaceutical Professionals’ Association (SABPA) will focus this year on new frontiers in cancer research. Topics include translational medicine, pharmacogenetics, personalized medicine, epigenetics, cancer stem cells, preclinical models, and oncology clinical design. Opportunities and challenges present in cancer drug development in San Diego life … Continue reading “The 10th SABPA Science & Technology Forum: Frontiers in Oncology”

Tuning into Wireless Health: Ideas and Opportunities in Life Sciences

The San Diego Entrepreneurs Exchange (SDEE) has invited prominent leaders in wireless health to talk about opportunities in this emerging sector of innovation and why San Diego has become a mecca for wireless health startups. Speakers include PatientSafe Solutions President Joe Condurso, Burrill & Co. Managing Director Dirk Lammerts, Independa CEO Kian Saneii, Qualcomm Ventures … Continue reading “Tuning into Wireless Health: Ideas and Opportunities in Life Sciences”

Connect and Xconomy Present: The Rock Stars of Innovation 1 Stop Tour

For the young entrepreneurs who work at the vanguard of innovation, there may be no more important topic to address in San Diego these days than the scarcity of venture funding. While venture funding nationwide has regained most of the ground lost during the Great Recession, the overall mix has been changing and the venture … Continue reading “Connect and Xconomy Present: The Rock Stars of Innovation 1 Stop Tour”

How Zite’s News App Altered the Zeitgeist in Personalized Publishing

It’s just past noon on March 30, 2011. The entire executive team from Zite is at the Sharon Heights Starbucks in Menlo Park—the usual hangout for entrepreneurs making the venture circuit. They’re killing time between VC meetings on Sand Hill Road, and they’re a little nervous. But it’s not because of the meetings, or the … Continue reading “How Zite’s News App Altered the Zeitgeist in Personalized Publishing”

SD Life Sciences (and Cleantech) Roundup: DexCom, Ligand, Genomatica

In addition to some advances on the life sciences front, we saw a flurry of developments among San Diego’s industrial biotechnology startups over the past week. —San Diego’s DexCom (Nasdaq: [[ticker:DXCM]]), which makes continuous glucose monitoring devices for patients with diabetes, acquired SweetSpot Diabetes Care, a Portland, OR, health IT company. DexCom said it will … Continue reading “SD Life Sciences (and Cleantech) Roundup: DexCom, Ligand, Genomatica”

Xconomist of the Week: Roger Perlmutter’s Parting Thoughts on Amgen

[Updated: 1:50 pm PT] Roger Perlmutter had a long run by biotech standards, a full 11 years, to put his stamp on R&D at Amgen. Some of the work he oversaw was unequivocally good (denosumab for osteoporosis and cancer), some bad (the EPO debacle), and some of the record is still a work in progress (44 … Continue reading “Xconomist of the Week: Roger Perlmutter’s Parting Thoughts on Amgen”

With $21.7M in New Funding, Luxtera Signs Deal to Make Optical Chip

Carlsbad, CA-based Luxtera, which recently raised $21.7 million in venture funding, says today it has signed a partnership with European semiconductor giant STMicroelectronics (NYSE: [[ticker:STM]]) to produce a new generation of chips that combine high-performance optics with silicon-based electronics. “We think it’s a really big deal,” says Chris Bergey, Luxtera vice president of marketing. “We’re … Continue reading “With $21.7M in New Funding, Luxtera Signs Deal to Make Optical Chip”

Organovo Obtains $8,331,977 New Financing Round

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=ed1450d9-a158-4004-866c-3c308536533a&Preview=1 Date 3/1/2012 Company Name Organovo Mailing Address 5871 Oberlin Drive San Diego, CA 92121 Company Description Organovo is focused on delivering breakthrough three-dimensional biology capabilities to create tissue on demand for research and surgical applications. As the first company with a three-dimensional tissue technology that works across tissue types, we are … Continue reading “Organovo Obtains $8,331,977 New Financing Round”

Second Sight Medical Products Secures $2,000,000 New Round

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=2decb326-8050-43a2-be23-963dbe3d60bd&Preview=1 Date 3/1/2012 Company Name Second Sight Medical Products Mailing Address 12744 San Fernando Road Building 3 Sylmar, CA 91342 Company Description Second Sight’s mission is to develop, manufacture and market implantable visual prosthetics to enable blind individuals to achieve greater independence. Website http://www.2-sight.com Transaction Type Venture Equity Transaction Amount $2,000,000 Transaction … Continue reading “Second Sight Medical Products Secures $2,000,000 New Round”

San Diego’s Young & Restless: A Cross-Section of Tech Entrepreneurs

After working over the past two years to help tech startups get started in San Diego, Brant Cooper tells me he’s sensing “a global renaissance in entrepreneurship.” It sure seems that way, if the attendance at a recent San Diego Tech Founders “demo night” is any guide. San Diego Tech Founders is a virtual grassroots … Continue reading “San Diego’s Young & Restless: A Cross-Section of Tech Entrepreneurs”

Sapphire Boosts Yields from Blue-Green Algae, Signs Earthrise Deal

In a move that extends the scope of its algal biofuel production, San Diego’s Sapphire Energy says it has modified certain cyanobacteria, also known as blue-green algae, to produce significantly higher yields of “green” crude oil. In a statement released today, Sapphire says it also has signed a licensing agreement with Earthrise Nutritionals, an Irvine, … Continue reading “Sapphire Boosts Yields from Blue-Green Algae, Signs Earthrise Deal”

Concert Nabs $200M Deal From Avanir to Make Psych Drugs

Lexington, MA-based Concert Pharmaceuticals has found a second partner looking to take advantage of its technology for making deuterium-modified drugs. Concert is announcing today that Aliso Viejo, CA-based Avanir Pharmaceuticals (NASDAQ: [[ticker:AVNR]]) has bought a worldwide license to Concert’s experimental drug that modifies dextromethorphan as a treatment for neurological and psychiatric disorders. Concert is getting … Continue reading “Concert Nabs $200M Deal From Avanir to Make Psych Drugs”

MBI Helps Biotech Companies De-Risk and Expand

MBI International, a wholly owned subsidiary of the Michigan State University Foundation, has an ambitious goal: To help Michigan’s bioeconomy sector grow by working with companies to negotiate the “valley of death”—taking their early-stage innovations to commercial viability, and, if failure is imminent, helping companies fail quickly before too much money is spent. That MBI … Continue reading “MBI Helps Biotech Companies De-Risk and Expand”

How Big Data Is Changing Everything

There’s a radical transformation happening in information technology today, one that promises to be every bit as significant—and every bit as disruptive to existing business models—as were Web applications in the 1990s and virtualization in the first decade of the 21st century. It’s a foundational change in the way enterprises, their employees, and their customers … Continue reading “How Big Data Is Changing Everything”

Hawken Receives $10,000,000 New Financing

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=e279db1e-7c19-465d-b136-a4d1974438f9&Preview=1 Date 2/28/2012 Company Name Hawken Mailing Address Undisclosed Alhambra, CA 91803 Company Description Aimed at hardcore gamers who battle each other online, Hawken is a fast-action shooting game where players can equip themselves with giant armored mech robotic suits and pummel each other in the ruined cities of a toxic planet. … Continue reading “Hawken Receives $10,000,000 New Financing”

The Promise of Personalized Medicine and the Challenges Ahead

Biocom is hosting John Sterling, the editor in chief of Genetic Engineering and Biotechnology News, for a conversation about personalized medicine that is intended to address a variety of looming issues, such as dealing with lifestyle choices like smoking and obesity, how reimbursement varies among different providers in different countries, and to identify the major … Continue reading “The Promise of Personalized Medicine and the Challenges Ahead”

San Diego Tech Roundup: Entropic, Xpenser, OneRoof Energy, & More

—A federal bankruptcy court in Delaware has tentatively approved a $65 million bid from San Diego’s Entropic Communications (NASDAQ: [[ticker:ENTR]]) to acquire system-on-a-chip technology that Trident Microsystems developed for its set-top box business. Entropic, which develops technology for connected home systems, had initially offered $55 million when the arrangement was disclosed in January. In a … Continue reading “San Diego Tech Roundup: Entropic, Xpenser, OneRoof Energy, & More”