Xconomists of the Week: Tom Maniatis and Marc Tessier-Lavigne Lead the Charge on the New York Genome Center

Today marked the official launch of the New York Genome Center, a collaboration among 11 top academic institutions that’s designed to accelerate genomic research. The initiative—supported by the City of New York and private and public institutions—is being guided by two of our Xconomists: Rockefeller University’s Marc Tessier-Lavigne, who will serve on the center’s board … Continue reading “Xconomists of the Week: Tom Maniatis and Marc Tessier-Lavigne Lead the Charge on the New York Genome Center”

Tablets, the Next Big Thing

We are at the beginning of the tablet revolution. Tablet computers are redefining the “mobile computing” space and taking the world of consumer electronics by storm. Four factors have come into play at an opportune time: physical design, functionality, broadband wireless, and the convenient availability of compelling apps through app stores. Such features have enabled … Continue reading “Tablets, the Next Big Thing”

Both Sword and Shield: Establishing Effective Intellectual Property in Bioscience

Bioscience companies rely more heavily on having an effective intellectual property portfolio than do companies based on other technologies. Often, the time required to reach product commercialization in biosciences is several years in the future. As a result, one of the greatest assets for the company is its intellectual property portfolio. Updated With Recent Court … Continue reading “Both Sword and Shield: Establishing Effective Intellectual Property in Bioscience”

SDEE Twofer: Janssen Labs Overview and the Importance of Being “Fundable”

The San Diego Entrepreneurs Exchange has invited Prescience International founder and CEO Melinda Richter to talk about the new Janssen Labs at San Diego, an incubator for early stage life sciences entrepreneurs. Prescience is managing the innovation center, which is designed as a flexible lab environment for start-up companies pursuing new technologies and research platforms … Continue reading “SDEE Twofer: Janssen Labs Overview and the Importance of Being “Fundable””

Infographic: College or Incubator for Startup Founders?

[Updated 11/4 at 2:30 pm] Not everyone can be a Gates, Allen, Jobs, or Zuckerberg—founders who dropped out of college and went on to change the technology industry by starting landmark companies. But there are more options available for budding entrepreneurs these days, most notably the explosion of incubators, accelerators, and other startup nurseries that … Continue reading “Infographic: College or Incubator for Startup Founders?”

TEDMED Walking, FDA Clears Pacira Drug, Zogenix Close to NDA, & More San Diego Life Sciences News

Drug approvals and advances in new cancer therapies were the prevailing themes in San Diego’s life sciences news over the past week. Our briefing begins now. —TEDMED, the exclusive medical and healthcare symposium that died in 2004 and was resurrected in 2009, is now the walking TEDMED. The entertaining show with a mix of big … Continue reading “TEDMED Walking, FDA Clears Pacira Drug, Zogenix Close to NDA, & More San Diego Life Sciences News”

Sanford-Burnham Joins Fold at Pfizer’s Centers for Therapeutic Innovation

San Diego’s Sanford-Burnham Medical Research Institute says today it’s joining the Centers for Therapeutic Innovation (CTI), a global network that New York-based Pfizer established a year ago to foster collaborations between basic research and clinical applications. The Pfizer network of drug discovery innovation centers includes academic medical centers in San Francisco, Boston, New York, and … Continue reading “Sanford-Burnham Joins Fold at Pfizer’s Centers for Therapeutic Innovation”

ProLacta BioSciences Receives Series D Funding Round

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=7e1a28c2-38e9-4fb4-84f3-82f7500e12e8&Preview=1 Date 11/3/2011 Company Name ProLacta BioSciences Mailing Address 605 E Huntington Dr. Monrovia, CA 91016 Company Description Prolacta Bioscience, headquartered in Monrovia, California is a life sciences company that provides specialty formulations of human milk for the immunological and nutritional needs of premature and critically ill infants. Website http://www.prolacta.com Transaction Type … Continue reading “ProLacta BioSciences Receives Series D Funding Round”

Scouting San Diego, Battelle Chemist Seeks Catalyzing Role as Industrial Biotech Arises Here

Like a lot of big companies that offer contract R&D and specialized services, Columbus, OH-based Battelle has kept an office in San Diego for decades, mostly to manage technical programs and help clients like the U.S. Navy and Marine Corps on special projects. That started to change, though, just over a year ago when Bhima … Continue reading “Scouting San Diego, Battelle Chemist Seeks Catalyzing Role as Industrial Biotech Arises Here”

Seeding Entrepreneurship: How to Build a Venture-Finance Ecosystem

[Editor’s note: Cross-posted from The Economist, 11/2/11] New York Mayor-entrepreneur Michael Bloomberg, not known for shyness, recently proclaimed New York City as America’s new entrepreneurship capital, roaring past Boston in venture capital and soon to leave Silicon Valley in the dust as the “go to” destination for entrepreneurs. Indeed, the world media are awash with … Continue reading “Seeding Entrepreneurship: How to Build a Venture-Finance Ecosystem”

Ophthonix Lands $14,046,415 New Financing Round

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=6c9eda74-b8f3-45b5-8cf5-c1bbe3f5ee34&Preview=1 Date 11/2/2011 Company Name Ophthonix Mailing Address 1491 Poinsettia Avenue Vista, CA 92081 Company Description Ophthonix Inc., a developer and marketer of advanced eyeglass lenses. The lenses aim to mimic the vision improvements rendered by the popular Lasik surgical procedure. Website http://www.izonlens.com Transaction Type Venture Equity Transaction Amount $14,046,415 Transaction Round … Continue reading “Ophthonix Lands $14,046,415 New Financing Round”

TechAmerica Names San Diego Tech Award Winners

It was 1993 when the San Diego chapter of the American Electronics Association organized its first high tech industry awards to recognize local companies for their business excellence, technology innovation, community involvement, and sometimes simply for persevering in the face of adversity. Since then, the nationwide organization that HP founder David Packard helped form in … Continue reading “TechAmerica Names San Diego Tech Award Winners”

Steel in Their Eyes—Why VCs should be Startup CEOs

A man who carries a cat by the tail learns something he can learn in no other way. —Mark Twain Venture capitalists who are serious about turning their firms into more than one-fund wonders may want to have their associates actually start and run a company for a year. Running a company is distinctly different … Continue reading “Steel in Their Eyes—Why VCs should be Startup CEOs”

Achates Power Cites “Huge” Improvement in Diesel Fuel Savings, Emissions

San Diego’s Achates Power, a startup developing a radical new design for a diesel-powered truck engine, is blowing its own air horn today about its progress in demonstrating significant improvements in the efficiency and performance of its engine. Through a series of tests that began just over a year ago, Achates says its prototype has … Continue reading “Achates Power Cites “Huge” Improvement in Diesel Fuel Savings, Emissions”

Biopharma Industry Meetings Could Use Some Fresh Voices

One or more notices of upcoming biopharma industry conferences arrive in my email every day. I give their agendas a quick glance before deleting them, as they’re seldom in areas I focus on. The vast majority of presenters are plucked from the ranks of top-tier Big Pharma; there’s a seminar from Pfizer, a speaker from … Continue reading “Biopharma Industry Meetings Could Use Some Fresh Voices”

The Economy in 17 Syllables, All of Them Gloomy

For the third quarter of 2011, the Ewing Marion Kauffman Foundation leavened its otherwise morose quarterly survey of economics bloggers (PDF) with something new: a haiku contest. The 63 academics, entrepreneurs, investors, and journalists who participated in the survey, including myself, were asked to describe the state of the economy in the form of a haiku, … Continue reading “The Economy in 17 Syllables, All of Them Gloomy”

Raising Funds: BillMyParents, Ortiva Wireless, and Organovo

[Corrected 11/3/11, 1:45 pm. See below.] A couple of tech fundings came through in recent regulatory filings, as well as a deal for Organovo, the San Diego medical device startup. Organovo’s scientific founder, Gabor Forgacs, was among the esteemed speakers at last week’s TedMed conference. Here are the details: [Corrected to explain filing] Organovo, the … Continue reading “Raising Funds: BillMyParents, Ortiva Wireless, and Organovo”

Pacira Wins FDA Approval of Pain Drug, Cushioning Pain of 3Q Loss

Parsippany, N.J-based Pacira Pharmaceuticals (NASDAQ: [[ticker:PCRX]]) announced today that the FDA approved its long-acting form of a pain drug called bupivacaine, which Pacira brands as Exparel. The approval marked a positive end to a bruising drug-development saga that began a dozen years ago. It also brightened up Pacira’s otherwise so-so third-quarter earnings, which the company … Continue reading “Pacira Wins FDA Approval of Pain Drug, Cushioning Pain of 3Q Loss”

Jobs at Center of UCLA Forecast, Sony Buys Out Partner, Wireless Health on Stage at CEA Forum, & More San Diego Biztech News

Economists from the UCLA Anderson Forecast and University of San Diego will break out details of their 2012 economic outlook at a conference in downtown San Diego this morning. The study was released earlier today. We have highlights, along with a roundup of last week’s San Diego tech news. —Job growth in the nation, state, … Continue reading “Jobs at Center of UCLA Forecast, Sony Buys Out Partner, Wireless Health on Stage at CEA Forum, & More San Diego Biztech News”

The Cancer Drug Dark Ages Are Coming to an End

Only a couple stories in the past decade have given advocates of personalized cancer medicines much to brag about. There was Genentech’s Herceptin for a form of breast cancer in 1998, and Novartis’ Gleevec for chronic myeloid leukemia in 2001. But just a few short weeks ago, in August, we saw a flurry of FDA … Continue reading “The Cancer Drug Dark Ages Are Coming to an End”

Ortiva Wireless Obtains $2,000,000 New Funding Round

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=531e6612-b034-40b0-a792-59a99c752c04&Preview=1 Date 10/31/2011 Company Name Ortiva Wireless Mailing Address 4225 Executive Square La Jolla, CA 92037 Company Description OrtivaTM Wireless delivers the smoothest video, clearest audio, and richest multimedia experience to mobile users under highly variable wireless network conditions. Our mobile network operator solutions extend the coverage and expand the availability of … Continue reading “Ortiva Wireless Obtains $2,000,000 New Funding Round”

BillMyParents Garners $2,542,500 New Funding Round

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=d464ac18-624e-49e7-aeb9-735b3154bad8&Preview=1 Date 10/31/2011 Company Name BillMyParents Mailing Address 6440 Lusk Blvd San Diego, CA 92121 Company Description BillMyParents, Inc. is a financial solutions company focused on helping teens and young adults between the ages of 13 and 18 to manage spending. Website http://www.billmyparents.com Transaction Type Venture Equity Transaction Amount $2,542,500 Transaction Round … Continue reading “BillMyParents Garners $2,542,500 New Funding Round”

Organovo Obtains $3,489,760 New Financing

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=d9d54ae3-62dd-4896-a532-7e7c7b9ed2cc&Preview=1 Date 10/31/2011 Company Name Organovo Mailing Address 5871 Oberlin Drive San Diego, CA 92121 Company Description Organovo is focused on delivering breakthrough three-dimensional biology capabilities to create tissue on demand for research and surgical applications. As the first company with a three-dimensional tissue technology that works across tissue types, we are … Continue reading “Organovo Obtains $3,489,760 New Financing”

Launching a New Medical Device in Foreign Markets

Amid complaints that the FDA is frustrating innovation in its processing of applications for new medical devices, Biocom has organized a discussion on an alternative. Many companies are now looking at markets outside of the U.S. for their initial launch. More information and online registration is here.

Global Life Sciences Partnering Conference

Biocom’s second Annual Global Life Science Partnering Conference is an exclusive global partnering and networking forum that brings together senior executives and business development professionals from leading pharmaceutical and biotech companies. More information and online registration is here.

A Case Study: Transplanting Aussie Expertise to Southern California

BCS Innovations in Australia recently established a sister company in San Diego, BCS Electronic Design, which is looking to transplant its reputation and establish a strong customer base in Southern California. The company has met some challenges in the marketplace, however, because their design team is not well known in the San Diego community. The … Continue reading “A Case Study: Transplanting Aussie Expertise to Southern California”

Ramifications of Patent Reform for Biomedical Companies

The most fundamental change implemented by the America Invents Act enacted earlier this year is the transition from a “first to invent” system for awarding patents to a “first inventor to file” system. This change, effective 18 months after enactment, awards priority to the first inventor to file a patent application and eliminates the ability … Continue reading “Ramifications of Patent Reform for Biomedical Companies”

Vinod Khosla Helps Startup Entrepreneurs Think Bigger

I had been planning to talk in today’s column about the shortcomings of the Google Chromebook, which are numerous. But I’m in too good of a mood this week to play the critic, partly because of a terrific Silicon Valley event that I attended Tuesday night called Get Bigger! With Vinod Khosla. So instead, I’m … Continue reading “Vinod Khosla Helps Startup Entrepreneurs Think Bigger”

Homeward Bound: Moving Health Care from Hospital to Home

A myriad of economic, political, and social forces are converging to drive the delivery of healthcare from the traditional hospital to lower-cost settings, including a relatively new concept called “the medical home.” CommNexus, San Diego’s nonprofit wireless and semiconductor industry group, has organized this session to explore the forces at work, the implications for patients, … Continue reading “Homeward Bound: Moving Health Care from Hospital to Home”

Vertex Flips Into the Black for First Time, as Hepatitis C Drug Beats Expectations Again

Vertex Pharmaceuticals has tallied up an amazing amount of red ink in its 22-year history, but now it can say that all those long R&D years have created a profitable business. The Cambridge, MA-based biotech company (NASDAQ: [[ticker:VRTX]]) said today that it generated $659 million in total revenues, and turned a profit of $221 million … Continue reading “Vertex Flips Into the Black for First Time, as Hepatitis C Drug Beats Expectations Again”

In a Detour From Device Strategy, Zogenix Edges Closer to New Drug Application

San Diego-based Zogenix, a specialty pharma that has been selling its first product (a fast-acting migraine drug in a single-dose injector) for 22 months, is getting ready to diversify its portfolio. As we reported in August, Zogenix successfully completed its late-stage safety and efficacy trials for an extended-release formulation of the painkilling drug hydrocodone bitartrate … Continue reading “In a Detour From Device Strategy, Zogenix Edges Closer to New Drug Application”

Agradis Takes Root, Illumina Cuts Back, Verenium Arranges Financing, & More San Diego Life Sciences News

It was another big week for life sciences news in San Diego, with interesting developments in agricultural biotech, industrial biotech, and genomic sequencing. This is our wrap up of what you need to know. —San Diego’s Synthetic Genomics spun out a new San Diego-based agricultural biotech, Agradis, with $20 million in Series A financing and … Continue reading “Agradis Takes Root, Illumina Cuts Back, Verenium Arranges Financing, & More San Diego Life Sciences News”

Xconomist of the Week: Phil Libin, Evernote, and the Death of the Exit

Xconomist Phil Libin, the CEO of Mountain View, CA-based Evernote, is a little unusual among his Silicon Valley brethren. He’s on the record as saying that the online notekeeping startup doesn’t want to be acquired. “There has never been an exit strategy at Evernote,” he wrote in an FAQ-style blog post after Evernote raised $50 … Continue reading “Xconomist of the Week: Phil Libin, Evernote, and the Death of the Exit”

BIO Investor Forum Roundup: Immune Design, Sorbent Therapeutics, Epizyme

The best thing about coming to the BIO Investor Forum in San Francisco every year is the schmoozing with folks from all over the country in one place. The worst thing? There’s not much in the way of breaking news. Oh well, sometimes you gotta do the spade work on a slow news day if … Continue reading “BIO Investor Forum Roundup: Immune Design, Sorbent Therapeutics, Epizyme”

Catalyzing Growth Through Regional Innovation Clusters

This three-day summit organized by Global Connect explores the potential behind academic partnerships, new financial models, and the critical role of government. Presenters include representatives from Janssen Healthcare Innovation (J&J), Qualcomm, Pfizer’s Centers for Therapeutic Innovation, Intel Capital, IBM Global Entrepreneurs Program. The conference also will showcase successful models for accelerating innovation, including TechStars, Johns … Continue reading “Catalyzing Growth Through Regional Innovation Clusters”

San Diego SuperData Summit

Every day “Big Data” analytics reveal fresh insights in healthcare, finance, and social media. The results are more accurate medical diagnoses, real-time fraud detection, custom-targeted advertising—and a gold mine of career opportunities. The San Diego Software Industry Council has organized this afternoon summit to cover a number of topics, including a demonstration of IBM Watson, … Continue reading “San Diego SuperData Summit”

23andMe Identifies Possible Protective Gene Against Parkinson’s Disease

The benefits of generating databases based on the personal genetics of thousands of people came into better focus today with an announcement from Mountain View, CA-based 23andMe, the startup that aspires to be the world’s trusted source for personal genetic information. Using genetic data drawn from thousands of 23andMe customers, the company says it has … Continue reading “23andMe Identifies Possible Protective Gene Against Parkinson’s Disease”

Illumina To Cut 200 Jobs, 8 Percent of Workforce, After Third Quarter Sales Fall Short

[Updated: 6:45 am, 10/26] San Diego-based Illumina is doing some restructuring to make up for third-quarter sales that fell way short of investors’ expectations. The market-leading maker of DNA sequencing instruments (NASDAQ: [[ticker:ILMN]]) said today it is going to restructure (i.e., make job cuts) that will add up to a $15 million to $17 million … Continue reading “Illumina To Cut 200 Jobs, 8 Percent of Workforce, After Third Quarter Sales Fall Short”

VC Slows, ViaSat Soars, Wests Unveil $100M Healthtech Fund, & More San Diego BizTech News

Data on venture capital investment activity during the third quarter poured in from different sources last week. The highlights are here, along with the rest of the San Diego’s biztech news. —Total venture capital invested in San Diego startups so far this year amounted to $567.7 million in 82 deals, according to the MoneyTree Report … Continue reading “VC Slows, ViaSat Soars, Wests Unveil $100M Healthtech Fund, & More San Diego BizTech News”

Zaarly Lands $14,100,000 Series A Round

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=34f60af5-6254-47ec-9ecb-2eceec6b276a&Preview=1 Date 10/25/2011 Company Name Zaarly Mailing Address Undisclosed Los Angeles , CA 90001 Company Description The company offers a proximity based, real-time buyer powered market application. Website http://www.zaarly.com Transaction Type Venture Equity Transaction Amount $14,100,000 Transaction Round Series A Proceeds Purposes Proceeds purposes were not disclosed. M&A Terms Venture Investor Kleiner … Continue reading “Zaarly Lands $14,100,000 Series A Round”

BlueCava Obtains $9,500,000 New Funding Round

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=66c092d0-6c3e-44b6-a86a-9601e113bcbb&Preview=1 Date 10/25/2011 Company Name BlueCava Mailing Address 2151 Michelson Dr. Irvine, CA 92612 Company Description The company has created the BlueCava Device Identification Platform that helps identify any device that is connected to the Internet. Website http://www.BlueCava.com Transaction Type Venture Equity Transaction Amount $9,500,000 Transaction Round Undisclosed Proceeds Purposes Proceeds purposes … Continue reading “BlueCava Obtains $9,500,000 New Funding Round”

Calient Networks Receives $19,400,000 New Round

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=470acfa4-d034-47da-b9cd-cc680a54bd84&Preview=1 Date 10/25/2011 Company Name Calient Networks Mailing Address 27 Castilian Drive Goleta, CA 93117 Company Description Calient Networks is a leading provider of intelligent, photonic switching systems and software that help service providers scale their networks for expanding bandwidth demands and deliver new wavelength services. Website http://www.calient.net Transaction Type Venture Equity … Continue reading “Calient Networks Receives $19,400,000 New Round”

Synthetic Genomics Spins Out Another Startup, Agradis, Focused on Agricultural Biotechnology

After spinning out a startup last year to develop next-generation vaccines, San Diego’s Synthetic Genomics says today it has joined forces with a Mexican investor to form Agradis, an agricultural biotech that will seek to commercialize its advances in plant breeding and genomics. With $20 million in Series A financing, Agradis is intended to accelerate … Continue reading “Synthetic Genomics Spins Out Another Startup, Agradis, Focused on Agricultural Biotechnology”

Xconomy Asks the Experts: Can Technology Innovation Really Lower the Cost of Healthcare?

Last week I was struck in particular by a comment that one reader appended to my post about the formation of a $100 million West Health Investment Fund by San Diego philanthropists Gary and Mary West. The Wests say they created the fund (and are providing the entire $100 million themselves) to invest in “cutting-edge” … Continue reading “Xconomy Asks the Experts: Can Technology Innovation Really Lower the Cost of Healthcare?”

Biotech VCs Have a Problem, and it Will Get Worse Before It Gets Better

We’ve heard warnings for a couple of years now that the chickens would come home to roost in the biotech venture capital scene. Quite a few VCs just haven’t delivered the returns to back up all their talk, and you can’t wait around forever for things to improve. This drama is going to be long … Continue reading “Biotech VCs Have a Problem, and it Will Get Worse Before It Gets Better”

GumGum Receives $7,000,000 New Funding Round

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=2fdb69d8-6741-4d74-91a8-021682ee356a&Preview=1 Date 10/24/2011 Company Name GumGum Mailing Address 530 Wilshire Blvd. Santa Monica, CA 90401 Company Description GumGum is a licensing and distribution platform for online content. We believe paying a flat rate to license content for online use is illogical. Offline, the flat rate model works because distribution is finite. Online, … Continue reading “GumGum Receives $7,000,000 New Funding Round”

From the Lab that Brought You Siri, It’s Trapit—A Personalized Discovery Engine

There are two kinds of people: Those who already own an iPhone 4S, and those who don’t but have seen Apple’s Siri ads and wish they did. Siri, of course, is the voice-operated personal assistant that can read your text messages, schedule appointments, check on the weather, make waffles, and babysit your toddler (just kidding … Continue reading “From the Lab that Brought You Siri, It’s Trapit—A Personalized Discovery Engine”

Q3 Venture Investing Waxed in Software, Internet, IT—Waned in Life Sciences

The numbers rarely agree, but a third set of venture investment data for the third quarter also shows a nationwide decline in life sciences funding, a trend that’s also apparent in venture data for the San Diego area. The latest venture survey, from Dow Jones VentureSource, shows VCs putting $8.37 billion into 765 deals in … Continue reading “Q3 Venture Investing Waxed in Software, Internet, IT—Waned in Life Sciences”