San Diego’s Afraxis Gets NIH Support to Develop Compound for Rare Fragile X Syndrome

Afraxis will partner with the NIH to advance work on the San Diego company’s disease-modifying treatments for Fragile X syndrome, a rare genetic disorder that is the most common inherited form of mental retardation, according to a statement from the company today. The biotech’s lead program targets p21-activated kinase (PAK), a protein that regulates the … Continue reading “San Diego’s Afraxis Gets NIH Support to Develop Compound for Rare Fragile X Syndrome”

Intuit Showcases New Apps, How San Diego’s Software Sector Could Come Together, OneRoof Energy Nails $50M, & More San Diego BizTech News

It was a busy week, with several meaty stories from San Diego’s tech front. Our Monday briefing is ready for your reading pleasure. —Jason Mendelson, a partner and co-founder of the Boulder, CO-based Foundry Group, talked about the factors that helped create a critical mass of new company formations and funding activity in Boulder’s software … Continue reading “Intuit Showcases New Apps, How San Diego’s Software Sector Could Come Together, OneRoof Energy Nails $50M, & More San Diego BizTech News”

Elevation Pharma Pulls in $17M to Advance Lung Drug Trial

San Diego-based Elevation Pharmaceuticals made headlines when it raised $30 million in January 2010, but it actually needed to hit some clinical goals to get all the money. Now it has hit one of those goals, and has earned the right to push further with a new aerosol drug for chronic obstructive pulmonary disease. Elevation … Continue reading “Elevation Pharma Pulls in $17M to Advance Lung Drug Trial”

200 Women and 5 Men: How Women in Bio’s Network Could Close the Gender Gap

Women have come a long way in the biotech business the past couple decades, no doubt. But if you have any illusions that the industry is nearing gender balance in 2011, then you haven’t seen what I witnessed a few days ago in a hotel lobby in Seattle. The gender balance issue jumped out at … Continue reading “200 Women and 5 Men: How Women in Bio’s Network Could Close the Gender Gap”

Elevation Pharmaceuticals Receives $17,000,000 Series A Financing

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=fe54e9a4-c4d7-4f34-b60d-b07cdaa80c77&Preview=1 Date 9/26/2011 Company Name Elevation Pharmaceuticals Mailing Address 11455 El Camino Real San Diego, CA 92130 Company Description Founded in 2008, Elevation Pharmaceuticals is developing a pipeline of improved aerosol drug products for COPD patients. Our founding team has a successful track record starting companies and building dedicated teams to develop … Continue reading “Elevation Pharmaceuticals Receives $17,000,000 Series A Financing”

“The Atlantic” Meets the Pacific at the Horizon of Energy, Technology, and Health

UC San Diego hosts the editors of The Atlantic magazine for three days of exploration and conversation on the future of energy, health, and technology. Hear from Twitter co-founder Evan Williams (in more than 140-characters), the Rocky Mountain Institute’s Amory Lovins, Deepak Chopra, Elon Musk, and The Atlantic’s James Fellows and James Bennet as they … Continue reading ““The Atlantic” Meets the Pacific at the Horizon of Energy, Technology, and Health”

A New Partner in Your Future? Biocom Looks Ahead With Dealmakers’ Survey

Biocom is hosting the Campbell Alliance to present the updated findings to its Dealmakers’ Intentions Survey, the only forward-looking measure of deal-making activity in the pharmaceutical and biotech industries. While there are many quality sources of information that look historically at past deal trends, this survey offers a prospective view of the partnering and licensing … Continue reading “A New Partner in Your Future? Biocom Looks Ahead With Dealmakers’ Survey”

The Breakfast Club: The UCSD Microgrid

The Procopio law firm has organized a cleantech and environmental “Breakfast Club” to examine the implementation of UC San Diego’s renewable energy “microgrid,” and its relationship to the conventional grid. This microgrid has captured the attention of industry leaders around the country; for example, Forbes magazine recently highlighted the importance of the smartgrid as a … Continue reading “The Breakfast Club: The UCSD Microgrid”

The San Diego Venture Group Hosts Its 12th Annual PitchFest Business Plan Competition

Let the winnowing begin. Attendees at the venture group’s annual “PitchFest” will hear presentations by promising Southern California companies that are seeking seed-stage capital. The audience will vote on three finalists who will make their presentation during the dinner. Based upon their votes, the SDVG will award a total of $17,500 in prize money to … Continue reading “The San Diego Venture Group Hosts Its 12th Annual PitchFest Business Plan Competition”

The Dating Game: Healthcare Chooses Between Entrepreneurs No.1, No.2, or No.3

The San Diego Venture Group is looking for a few game-changing healthcare technologies to reprise a venture version of “The Dating Game.” If you’re a startup CEO with a company that focuses on improved health outcomes, you could be one of three eligible entrepreneurs who will get to play for a “date” (i.e. a one … Continue reading “The Dating Game: Healthcare Chooses Between Entrepreneurs No.1, No.2, or No.3”

Navigating the Markets Three Years after the Financial Crisis

Standard & Poor’s unprecedented downgrade of the U.S. national debt, coupled with Europe’s debt crisis, has caused the economic recovery to be uneven, impacting investors, retirement security, corporate profitability, and investment opportunities in the stock, bond, and derivatives markets. The USD law school has organized a panel of experts to provide insights and help guide … Continue reading “Navigating the Markets Three Years after the Financial Crisis”

SDEE Entrepreneurs Roundtable: Supporting a Startup with Grants

The San Diego Entrepreneurs Exchange is hosting a panel discussion on how to start and sustain a business by leveraging funding from grants. Speakers include Greg Hook of American Life Science Pharmaceuticals, John Cashman of the Biomolecular Research Institute and Kenneth Abeloe of Integrity Applications. Attendance is free, but please register online here.

Biomimicry Reception Series

Shrimp-inspired body armor. Nano-scale energy generation. In this biomimicry reception UC Riverside Professor David Kisailus and his students share how they look to nature in designing the next generation of engineering products and materials. Additionally this reception will feature wine, appetizers, and a special biomimicry-themed animal encounter. More information and online registration is here.

Third Annual Maritime Business & Technology Summit

The Maritime Alliance has organized its third annual Maritime Business & Technology Summit to promote advances in maritime technology and business opportunities in the global maritime technology industry. The two-day conference is intended to bring together academia, government, industry, and military interests to promote innovation, maximize business and networking opportunities, and to draw companies from … Continue reading “Third Annual Maritime Business & Technology Summit”

Turning the Social Network Inside Out: What the Changes at Facebook Mean For Apple and Google-and You

One of the most persistent criticisms of Facebook is that it’s trying to build a “walled garden” analogous to AOL’s dialup service in the 1980s and early 1990s. Blogger Jason Kottke said it in 2007. Tim Berners-Lee said it in Scientific American in 2010. Google’s Vint Cerf revived the meme earlier this week at an … Continue reading “Turning the Social Network Inside Out: What the Changes at Facebook Mean For Apple and Google-and You”

With $50M Deal, San Diego Company Combines PV Solar, Financing, and New Roof

One of South Korea’s largest conglomerates led a $50 million Series A financing for OneRoof Energy, a San Diego company with a leasing program that enables homeowners to install photovoltaic (PV) solar tiles on their roofs without paying upfront costs. The company says Hanwha International, part of the Seoul-based Hanwha Group, is getting a “significant, … Continue reading “With $50M Deal, San Diego Company Combines PV Solar, Financing, and New Roof”

How to Build a Web Startup: Lean LaunchPad Edition

As part of our Lean LaunchPad classes at Stanford, Berkeley, Columbia and for the National Science Foundation, students build a startup in 8 weeks using Business Model Design + Customer Development. One of the problems they run into is building a website. If you’re an experienced coder and user interface designer you think nothing is … Continue reading “How to Build a Web Startup: Lean LaunchPad Edition”

Ambrx Grabs $24M Upfront in New Diabetes, Heart Failure Research Deal With Bristol-Myers

There’s lots of interest in the protein drug engineering crowd to come up with new-and-improved forms of biotech drugs, and today we’re seeing another example in a new partnership between San Diego-based Ambrx, and New York-based Bristol-Myers Squibb (NYSE: [[ticker:BMY]]). Under the deal, Ambrx said today it will get $24 million upfront, plus undisclosed milestone … Continue reading “Ambrx Grabs $24M Upfront in New Diabetes, Heart Failure Research Deal With Bristol-Myers”

Money Goes Mobile: Video from Intuit’s Innovation Gallery Walk

Wednesday was Investor Day at the Mountain View, CA, headquarters of Intuit, the 28-year-old consumer and business finance software giant. Most attendees were there to hear about the company’s fiscal strategy for 2012—and if that’s your cup of tea, there’s a recorded webcast of the meeting here. But Xconomy attended for a different reason—to see … Continue reading “Money Goes Mobile: Video from Intuit’s Innovation Gallery Walk”

Orexigen’s Diet Drug Springs Back to Life, Independa Gets $1.6M, NuVasive Faces Big Judgments in Patent Dispute, & More San Diego Life Sciences News

San Diego life sciences research and development, the engine that drives innovation, got some new digs at Isis Pharmaceuticals, and J. Craig Venter started the digging for the construction of a new genomics research headquarters. But we didn’t have to go digging for news; our roundup begins now. —After meeting with federal regulators, San Diego’s … Continue reading “Orexigen’s Diet Drug Springs Back to Life, Independa Gets $1.6M, NuVasive Faces Big Judgments in Patent Dispute, & More San Diego Life Sciences News”

Xconomist of the Week: Ben Elowitz Goes Deep with TV Gossip, Maps the Future of Media

What does “Jersey Shore” star Snooki have to do with the future of online media? Plenty, it turns out. That’s one of the surprising things I learned recently chatting with Ben Elowitz, the CEO of Seattle-based Wetpaint, a well-financed startup that’s about a year into its newest mission: Trying to reinvent how content is created … Continue reading “Xconomist of the Week: Ben Elowitz Goes Deep with TV Gossip, Maps the Future of Media”

TechStars Raises $24M More, Offers Each Startup $100K; Founder David Cohen Talks “Quality Over Quantity”

The early-stage tech accelerator business just got even more competitive. Boulder, CO-based TechStars, which runs seed-stage mentorship programs for startups in Boulder, Boston, Seattle, and New York, announced today it has raised a new $24 million fund from a long list of investors that includes Foundry Group, IA Ventures, Avalon Ventures, DFJ Mercury, SoftBank Capital, … Continue reading “TechStars Raises $24M More, Offers Each Startup $100K; Founder David Cohen Talks “Quality Over Quantity””

San Diego’s Independa Raises $1.6M for Technology to Help Elderly Stay Independent

[Corrected 9/21/11, 1:05 pm. See below.] Independa, the San Diego startup developing Web-based services for the elderly, says it has closed on $1.6 million in early stage financing, and investor interest has been strong enough to extend the round to $2.2 million. [Corrected to show $200,000 loan is in addition to $1.6M investment] Independa CEO … Continue reading “San Diego’s Independa Raises $1.6M for Technology to Help Elderly Stay Independent”

JustFabulous Secures $33,000,000 Series A Funding

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=585a1791-ce91-48d9-a38c-ced56df96b5a&Preview=1 Date 9/21/2011 Company Name JustFabulous Mailing Address 2301 Rosecrans Ave El Segundo, CA 90245 Company Description At JustFabulous, we believe that every woman deserves to wear the same fashion-forward designs as the rich and famous regardless of her social status. Not to mention the fact that establishing an on-trend wardrobe filled … Continue reading “JustFabulous Secures $33,000,000 Series A Funding”

Orexigen Revives Obesity Drug After One More Go-Round With FDA

Orexigen Therapeutics was left for dead earlier this year when its obesity drug was shot down by the FDA. But today it had a message for investors that could be interpreted as “hold on, we might not be dead yet after all.” The San Diego-based biotech company (NASDAQ: [[ticker:OREX]]) said today that has decided to re-start … Continue reading “Orexigen Revives Obesity Drug After One More Go-Round With FDA”

New Citrix Startup Accelerator Makes Seed Investment in San Diego’s Nukona

Nukona, a Solana Beach, CA-based software developer that enables IT administrators to manage consumer-oriented mobile apps, says today it has closed on a funding round led by Citrix Systems’ Startup Accelerator program in Santa Clara, CA. The corporate incubator program was launched earlier this year by Fort Lauderdale, FL-based Citrix Systems. The accelerator program, which … Continue reading “New Citrix Startup Accelerator Makes Seed Investment in San Diego’s Nukona”

Jason Mendelson, the Elvis of Innovation, Offers Some Lessons for San Diego’s Tech Sector

I like you. Just maybe you’ve got a clue Meet my partners on a Monday, We’ll see if they can dig you too ‘Cuz I’m a VC, I’m a VC I drive around a Prius and meet over sushi I’m a VC. Uh-huh. Who are you? It takes more than PowerPoint slides to impress me … Continue reading “Jason Mendelson, the Elvis of Innovation, Offers Some Lessons for San Diego’s Tech Sector”

FDA at the Center of Huge Gray Area in Establishing Regs for Wireless Health, Execs Say

When Rob McCray founded San Diego’s Wireless Life Sciences Alliance (WLSA) in 2005, the group’s corporate membership constituted just three companies: Qualcomm; Johnson & Johnson; and TripleTree, a boutique banking and research firm where McCray was a partner. Since then, the convergence of healthcare and wireless technologies has become more obvious, and the WLSA has … Continue reading “FDA at the Center of Huge Gray Area in Establishing Regs for Wireless Health, Execs Say”

Plunging Valuations and Surplus of Groupon Clones Sets Off Frenzy of M&A Activity

Buyouts and mergers of Web companies that offer online “daily deals” have accelerated sharply over the past five months, driven by a rapid decline in valuations and a surplus of Groupon clones, according to a report issued today by CB Insights, a New York data services firm. CB Insights counted 22 global mergers and acquisitions … Continue reading “Plunging Valuations and Surplus of Groupon Clones Sets Off Frenzy of M&A Activity”

Coda Automotive Lands $71,000,000 Series D Funding Round

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=4b6e93b8-8a6f-4585-ba59-7a9c4349cabe&Preview=1 Date 9/20/2011 Company Name Coda Automotive Mailing Address 1601 Wilshire Blvd Santa Monica, CA 90403 Company Description CODA Automotive is a privately held company headquartered in Santa Monica, California that designs, manufactures and sells electric vehicles and lithium-ion battery systems purpose-built for transportation and utility applications. Website http://www.codaautomotive.com Transaction Type Venture … Continue reading “Coda Automotive Lands $71,000,000 Series D Funding Round”

Stirring the Pot Once in a While Doesn’t Hurt, and It Could Help Biotech Break its Malaise

Listen to enough biotech industry leaders talk in public, and you’ll hear a lot of carefully scripted comments. Everyone can list off their corporate milestones on a PowerPoint slide, and utter some politically correct platitudes about novel technology, helping patients, having a “good working relationship” with the FDA, constructive partnership talks. Blah, blah, blah. Rarely … Continue reading “Stirring the Pot Once in a While Doesn’t Hurt, and It Could Help Biotech Break its Malaise”

A Day in the Life of the San Francisco Tech Community

My job is pretty cool. I get to spend time picking the brains of some of the planet’s smartest and most successful entrepreneurs—and invariably, I’m asking them to talk about the one thing they care about most passionately, their startup and/or its technology. Even if I weren’t doing something I care about passionately myself—helping to … Continue reading “A Day in the Life of the San Francisco Tech Community”

Entrepreneur Walk of Fame Opens in Kendall Square: Gates, Jobs, Kapor, Hewlett, Packard, Swanson, and Edison are Inaugural Inductees

It was a little over a year ago that Xconomy broke the news that a movement was underway to bring an Entrepreneur Walk of Fame to Kendall Square in Cambridge, MA, modeled after its Hollywood namesake. The idea makes a lot of sense: If we celebrate movie stars and athletes, why not the top innovators … Continue reading “Entrepreneur Walk of Fame Opens in Kendall Square: Gates, Jobs, Kapor, Hewlett, Packard, Swanson, and Edison are Inaugural Inductees”

Merck Joins the Big Pharma VC Party, Setting Up $250M Biotech Investment Fund

[Updated with Merck comment 1:25 pm ET, 9/16] Just about all the major pharmaceutical companies have their own venture capital funds to invest in biotech startups, and now one of the real biggies, Whitehouse Station, NJ-based Merck, has joined the club. Merck (NYSE: [[ticker:MRK]]) has established the new Merck Research Venture Fund (MRVF) with $250 … Continue reading “Merck Joins the Big Pharma VC Party, Setting Up $250M Biotech Investment Fund”

Sequoia Leads $30M Round for Visualization App-Maker MeLLmo

Del Mar, CA-based MeLLmo, which provides visualization software that transforms data from spreadsheets and other business software into interactive graphics for the iPhone and iPad, says today it has secured $30 million through a round led by Sequoia Capital. This is MeLLmo’s first round of institutional financing. The startup had previously raised $20 million from … Continue reading “Sequoia Leads $30M Round for Visualization App-Maker MeLLmo”

Ion Torrent Racing to Change Healthcare, VentiRx to Close SD Office, RF Surgical Raises $12M, and More San Diego Life Sciences News

San Diego’s biggest life sciences stories over the past week were fundamentally about the potential of new technologies. We’ve got what’s happening at Life Technologies’ Ion Torrent and Panmira Pharmaceuticals wrapped up for you here. —Luke talked with Ion Torrent founder Jonathan Rothberg about the company’s increasingly high profile in sequencing genomes at high speed … Continue reading “Ion Torrent Racing to Change Healthcare, VentiRx to Close SD Office, RF Surgical Raises $12M, and More San Diego Life Sciences News”

Silicon Valley’s Pay-It-Forward Culture

Foreign visitors to Silicon Valley continually mention how willing we are to help, network and connect strangers. We take it so for granted we never even to bother to talk about it. It’s the “Pay-It-Forward” culture. The Chips are Down in 1962 Walker’s Wagon Wheel Bar/Restaurant in Mountain View became the lunch hangout for employees … Continue reading “Silicon Valley’s Pay-It-Forward Culture”

Accumetrics CEO Measures Progress of Its Medical Diagnostics Business

Accumetrics CEO Tim Still tells me much has changed since I profiled the San Diego medical diagnostics company in 2009. The venture-backed company makes an automated diagnostic instrument that uses a disposable test kit to measure a cardiovascular patient’s specific response to anti-clotting drugs. More than a million Americans are hospitalized each year due to … Continue reading “Accumetrics CEO Measures Progress of Its Medical Diagnostics Business”

Xconomist of the Week: Reed Sturtevant of Lotus, Idealab, and Microsoft Fame Talks Tech Trends to Watch

You know the type. He’s at every tech startup event, every investor event, and every incubator and early-stage mentorship session (at least every good one). He’s talked to every entrepreneur in the area and has had a hand in the development of many of their companies. He has been a fixture of the local software … Continue reading “Xconomist of the Week: Reed Sturtevant of Lotus, Idealab, and Microsoft Fame Talks Tech Trends to Watch”

Ion Torrent’s Fast and Cheap DNA Sequencer Catches On, Even as Biologists Tighten Belts

Ask Jonathan Rothberg a few questions about his new venture in DNA sequencing, and, ever the showman, he find references to a pivotal event in world history while delivering what amounts to a “no comment.” The questions were basic enough: How many employees do you have in San Francisco and Guilford, CT? How much has … Continue reading “Ion Torrent’s Fast and Cheap DNA Sequencer Catches On, Even as Biologists Tighten Belts”

IPOs Look Dicey, But Private Equity May Pick Up Some Of The Slack

For a while, I was optimistic that 2011 would be a good year for venture capital-backed IPOs, and it wasn’t just wishful thinking. There were 72 VC-backed IPOs last year—six times as many as in 2009. The year ended with a bang and 2011 got off to a good start. In the first half of … Continue reading “IPOs Look Dicey, But Private Equity May Pick Up Some Of The Slack”

FireScope Lands $1,706,070 New Round

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=8362aee8-b536-4133-81e3-1776a5f2e5a1&Preview=1 Date 9/15/2011 Company Name FireScope Mailing Address 2130 Main Street Huntington Beach, CA 92648 Company Description FireScope IT Service Management Solutions help remove barriers and delivers a powerful framework for the development and day-to-day management of your comprehensive IT strategy. Website http://www.firescope.com Transaction Type Venture Equity Transaction Amount $1,706,070 Transaction Round … Continue reading “FireScope Lands $1,706,070 New Round”

Celerus Diagnostics Receives $10,000,000 Series C Funding Round

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=b03af0bf-b73a-4e82-b23a-53e7088488f7&Preview=1 Date 9/15/2011 Company Name Celerus Diagnostics Mailing Address 1005 Mark Ave Carpinteria, CA 93013 Company Description Celerus Diagnostics is focused on addressing the unmet needs of the Anatomic Pathology Laboratory. As a partner to the Pathologist, Celerus is developing diagnostic testing systems designed to provide real time solutions for Cancer Patient … Continue reading “Celerus Diagnostics Receives $10,000,000 Series C Funding Round”

Kythera Biopharmaceuticals Receives $37,424,989 Series D Financing Round

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=886a13fd-f51a-4fcc-8052-bc499ab45596&Preview=1 Date 9/15/2011 Company Name Kythera Biopharmaceuticals Mailing Address 27200 West Agoura Road Calabasas, CA 91301 Company Description Kythera is focused on science and innovation in aesthetic and restorative dermatology. These markets are expanding rapidly driven by an aging population, increasing discretionary income, and an evolution of patient preference toward restorative and … Continue reading “Kythera Biopharmaceuticals Receives $37,424,989 Series D Financing Round”

MeLLmo Obtains $30,000,000 New Funding Round

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=00b9f8c9-fb05-4f58-ac50-61ca62998f53&Preview=1 Date 9/15/2011 Company Name MeLLmo Mailing Address 2002 Jimmy Durante Blvd Del Mar, CA 92014 Company Description MeLLmo Inc. is a privately funded software company setting out to solve this challenge. Founded in January 2008, with offices in San Diego and Santa Monica, MeLLmo’s goal is to create revolutionary ways to … Continue reading “MeLLmo Obtains $30,000,000 New Funding Round”

Computing in the Age of the $1,000 Genome. Our Next Big Event in SF Oct. 24

The $1,000 genome is coming fast, whether society is ready for it or not. This field has moved so fast, reasonable people have estimated we will have sequenced millions of genomes within a few years. It’s even conceivable that individuals will get sequenced more than once in a lifetime, to track how their health is … Continue reading “Computing in the Age of the $1,000 Genome. Our Next Big Event in SF Oct. 24”

10 Surprises of a First-Time Entrepreneur

As a young entrepreneur, I cannot overstate the importance of serendipity. I don’t know whether I’ll ultimately be successful or not, but the success I’ve had so far has been 10 percent inspiration, 90 percent perspiration, and 50 percent surprises. And if you’re saying that this adds up to 150 percent—you’re catching on to my … Continue reading “10 Surprises of a First-Time Entrepreneur”

RF Surgical Adds $12M to Make Sure Surgeons Don’t Leave Sponges Inside Patients

RF Surgical, the Bellevue, WA-based maker of technology to make sure surgical sponges aren’t left inside patients, has raised another $12 million in venture capital. Split Rock Partners, a new investor, joined the financing round along with previous investors Menlo Ventures, Stanford University, and two of the company founders. Back in November, when I wrote … Continue reading “RF Surgical Adds $12M to Make Sure Surgeons Don’t Leave Sponges Inside Patients”