Category: San Diego

Shipping Wars: Walmart Launches Free Delivery for Sam’s Club Members

In order to better position itself against competitors like Costco Wholesale (NASDAQ: [[ticker:COST]]) and Amazon (NASDAQ: [[ticker:AMZN]]), Sam’s Club, the bulk retailer owned by Walmart (NYSE: [[ticker:WMT]]), is now offering free shipping for many items as part of a revamping of its membership programs. With a $100 annual fee—just one dollar more than the cost … Continue reading “Shipping Wars: Walmart Launches Free Delivery for Sam’s Club Members”

Startups Peddle Innovative Tools to Fight Tech’s #MeToo Problem

As the last year has shown, the tech industry has a significant problem with sexual harassment and ensuring that women are treated equitably in the workplace. Now, some founders are seeking to use tech tools such as chatbots, artificial intelligence, analytics, and mobile to help clients remedy those deficiencies. One of those founders is Heather … Continue reading “Startups Peddle Innovative Tools to Fight Tech’s #MeToo Problem”

With Qualcomm Buyout Looming, EvoNexus Aims for Self-Sufficiency

In the nine years since San Diego’s EvoNexus incubator began amid the great recession of 2009, CEO Rory Moore has emphasized it is a pro bono program—startup teams admitted to the technology accelerator get free office space and other perks, with no strings attached. EvoNexus operates as a non-profit, which is possible because dozens of … Continue reading “With Qualcomm Buyout Looming, EvoNexus Aims for Self-Sufficiency”

FDA’s Rachel Sherman on Right to Try, Succession Trouble & More

The opioid crisis. Right to Try legislation. The first human trials of CRISPR-Cas9 gene editing technology. These are just a few of the many topics at the feet of the FDA this year. Speaking at the BIO CEO & Investor Conference in New York on Tuesday, principal deputy commissioner Rachel Sherman, the FDA’s second in … Continue reading “FDA’s Rachel Sherman on Right to Try, Succession Trouble & More”

Trump Budget Touts Lower Drug Prices, But No Medicare Negotiation

As president-elect, Donald Trump in January 2017 slammed drug companies for “getting away with murder” and said he supported Medicare negotiation. He vowed during last month’s State of the Union speech that drug prices “will come down.” Today, his administration’s fiscal 2019 budget proposal laid out what it calls a “comprehensive” strategy to lower drug … Continue reading “Trump Budget Touts Lower Drug Prices, But No Medicare Negotiation”

Buying Shoes? Digital Stylists Use A.I. to Suggest Clothing to Match

The black skirt had multiple personas. The fact that it was made of leather gave it an edgy vibe, but its A-line fit-and-flair cut was more flirty and feminine. “I fell in love with it,” says Michelle Bacharach, co-founder of FindMine. “But as soon as I brought it home, I wondered, ‘how do I wear … Continue reading “Buying Shoes? Digital Stylists Use A.I. to Suggest Clothing to Match”

Execs Talk Hurdles As Immunotherapy Combos, CAR-T Launches Progress

With multiple products on the market and many more coming, it’s easy to think that cancer immunotherapy has arrived. In reality, however, we’ve only just begun to figure out how to coax the immune system into killing cancer. That’s why a mad dash is on to expand its reach, and a panel of experts invested … Continue reading “Execs Talk Hurdles As Immunotherapy Combos, CAR-T Launches Progress”

As Trump Budget Addresses Opioid Crisis, BIO Report Reveals Scarce Pain Drug Development

[Updated 2/12/2018, 1:37pm ET, see below.] With the opioid epidemic showing little sign of letting up, new ways of treating chronic pain are desperately needed. But the development of non-addictive, non-opioid pain drugs lags far behind drug R&D for other diseases (I wrote a few months ago about why that is), and a report from … Continue reading “As Trump Budget Addresses Opioid Crisis, BIO Report Reveals Scarce Pain Drug Development”

Bio Roundup: Lung Cancer Questions, Migraine Races, HIV Battle & More

The top biopharma story of the week involves the fast-moving field of lung cancer, which, as we’ve written previously, has several key trials reading out in 2018. A big domino fell this week: data from a two-drug immunotherapy combination developed by Bristol-Myers Squibb. But the results, touted as positive, left more questions than answers. First, … Continue reading “Bio Roundup: Lung Cancer Questions, Migraine Races, HIV Battle & More”

Instant Gratification: Whole Foods, Target Offer Same-Day Delivery

[Updated 2/8/18, 1:39 pm.] The race is on to sign up consumers seeking same-day delivery of groceries, household items, and personal goods. Late on Wednesday, Amazon (NASDAQ: [[ticker:AMZN]]) announced it has started free two-hour delivery of products from Whole Foods Market, the most significant example of the e-commerce giant using technology at the Austin, TX-based … Continue reading “Instant Gratification: Whole Foods, Target Offer Same-Day Delivery”

Rep. Jared Polis Asks Congress to Disclose Cryptocurrency Holdings

Members of Congress are required to disclose many details about their personal finances. Jared Polis, a Democratic U.S. Representative from Colorado—and a successful Internet entrepreneur—contends that elected representatives and certain staffers should also be required to disclose cryptocurrencies like Bitcoin and Ethereum, even though that’s not necessarily happening now. Polis wants it to become a … Continue reading “Rep. Jared Polis Asks Congress to Disclose Cryptocurrency Holdings”

At Verastem, Infinity’s Former Blood Cancer Drug Heads to FDA

Verastem has filed for FDA approval of duvelisib, a blood cancer drug the Needham, MA, company took a shot on in a 2016 bargain deal with Infinity Pharmaceuticals. Verastem will seek approval of duvelisib as a treatment for patients who have one of three different blood cancers—chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma, or follicular … Continue reading “At Verastem, Infinity’s Former Blood Cancer Drug Heads to FDA”

Medical and Patient Groups Warn Congress Against “Right to Try”

Dozens of medical organizations and patient advocacy groups are pushing back against so-called “right-to-try” legislation that passed the Senate in August and is now under consideration in the House. An open letter sent today to House leaders is the latest opposition to the Republican-led push to give desperate patients access to experimental drugs without FDA … Continue reading “Medical and Patient Groups Warn Congress Against “Right to Try””

Walmart Brings Virtual Reality to Retail With Purchase of Spatialand

Walmart’s tech incubator in Silicon Valley, Store No 8, has acquired Spatialand, a virtual reality software firm, as its third portfolio company. While much of the focus in using VR has been on gaming and entertainment, “virtual reality has the potential to reinvent the consumer experience—with an experience we call contextual commerce,” according to a … Continue reading “Walmart Brings Virtual Reality to Retail With Purchase of Spatialand”

A16Z Bio Fund’s Pande Sees A.I. as Way to Ride Bio Innovation

As Andreessen Horowitz begins to invest the $450 million the bellwether venture firm recently raised for its second bio fund, general partner Vijay Pande has been talking increasingly about the use of artificial intelligence in the life sciences. In a presentation a few months ago at the firm’s annual a16z Summit, Pande argued that many … Continue reading “A16Z Bio Fund’s Pande Sees A.I. as Way to Ride Bio Innovation”

Pay It Forward: Capital Drives Bio Innovation in San Diego & Beyond

After starting Organovo in 2007, I spent much of the next decade as CEO seeking financing to advance our bioprinting technology. Because I stepped out of an operational role early last year, I am now in a position of providing financing to aspiring life sciences entrepreneurs.  The change has caused me to reflect a bit … Continue reading “Pay It Forward: Capital Drives Bio Innovation in San Diego & Beyond”

E-Commerce Firm Dearduck Uses A.I. in the Hunt for the Perfect Gift

Houston—Knowledge is power, but too much of a good thing can render data meaningless. That’s the struggle many retailers have in an age of data analytics. Think about the retailer e-mails we receive daily or the ads that appear on Google or our social media sites. Though based on our Web searches, those ads don’t … Continue reading “E-Commerce Firm Dearduck Uses A.I. in the Hunt for the Perfect Gift”

Entrepreneurs Look to Angels and Micro-VCs for Cash

You don’t need me to tell you it’s a rough world out there for startups. Venture capitalists have been unusually stingy lately, hanging on to billions of dollars they’d typically be channeling into promising young companies. When those investors do open their wallets, they’re shunning risky investments in favor of what the Wall Street Journal … Continue reading “Entrepreneurs Look to Angels and Micro-VCs for Cash”

Arcturus Terminates CEO, Names Mark Herber as Interim President

Arcturus Therapeutics (NASDAQ: [[ticker:ARCT]]) said today it has fired co-founder and CEO Joseph E. Payne (on the right in above photo), and named Mark Herber, vice president of business development and alliance management, as interim president. The San Diego-based early stage biotech, which specializes in RNA medicines, did not explain in a statement today why … Continue reading “Arcturus Terminates CEO, Names Mark Herber as Interim President”

Bio Roundup: Wilson’s Warning, Amazon’s Health Biz, Moderna Cash & More

The State of the Union address was…. long. At one hour and 20 minutes, President Trump fell about 9 minutes shy of the high mark. But those who stayed tuned in heard comments about several health policy matters. The president credited the FDA for a record number of generic drug approvals in 2017, which PwC … Continue reading “Bio Roundup: Wilson’s Warning, Amazon’s Health Biz, Moderna Cash & More”

Xconomy Bookclub: “Inferior” Peruses Science’s Historic #MeToo Bias

In his now infamous memo, ex-Google engineer James Damore cited scientific evidence to illustrate why women may not be suited for jobs at some of today’s leading tech companies. Women, he argued, are biologically more attuned to “people” jobs rather than “thing” jobs, like those in technology. But what Damore was doing, others pointed out, … Continue reading “Xconomy Bookclub: “Inferior” Peruses Science’s Historic #MeToo Bias”

As Worlds Collide: Join Xconomy for Big Data Meets Big Biology

What happens when the power of advanced computing and large-scale data technologies are applied in healthcare and the life sciences? Imagine what might happen if two tsunamis came together near the coast. On April 26, Xconomy will explore how the inexorable trends in IT and life sciences are driving transformational change, and how innovations in … Continue reading “As Worlds Collide: Join Xconomy for Big Data Meets Big Biology”

With Pellini on Board, Maris Sets Course at Section 32

It’s not easy to catch up with Bill Maris at Section 32, the venture firm he founded last year near San Diego. It took a while to arrange a call to discuss how Foundation Medicine’s Michael Pellini had joined Section 32 as Maris’s first investing partner, and what they plan to do together. Maris acknowledged … Continue reading “With Pellini on Board, Maris Sets Course at Section 32”

Look Out, Investors: Cryptocurrency Values Slide As Warnings Take Off

Bitcoin and other cryptocurrencies have seen dramatic but volatile price surges during the past year. But this month their billions in estimated market value are eroding, amid widening suspicions against one trading platform, a half-billion-dollar heist from another exchange, and an awakened global regulatory community. Warnings are on the rise from regulators, researchers, banking executives—and … Continue reading “Look Out, Investors: Cryptocurrency Values Slide As Warnings Take Off”

Google Pulls Plug on Webpass in Boston Amid Growing Competition

In another setback for Google’s Internet business, the tech giant has decided to wind down the Boston-area operations of Webpass, a wireless Internet service provider Google Fiber acquired in June 2016. A statement e-mailed by a Google spokeswoman didn’t give a reason for the decision. “We’ll work with customers and partners to minimize disruption, and … Continue reading “Google Pulls Plug on Webpass in Boston Amid Growing Competition”

As A.I. Takes Off, We Need a Plan to Deal with Societal Disruption

As an Xconomist, I have been asked to predict what technology might really take off in 2018. My response is something of a “cheat” in that it relates to artificial intelligence (AI), a technology that has been poised to take off next year for the past several decades and a topic about which I have … Continue reading “As A.I. Takes Off, We Need a Plan to Deal with Societal Disruption”

After Paper Shakes Sector, Gene Therapy Leader Jim Wilson Talks Safety

[Updated, 1/31/18, see below] Gene therapy pioneer James Wilson and University of Pennsylvania colleagues sounded an alarm Tuesday morning about the use of gene therapy to treat severe diseases like spinal muscular atrophy and Duchenne muscular dystrophy, sending a chill across the sector. Shares of several companies inched downward as word spread about the UPenn … Continue reading “After Paper Shakes Sector, Gene Therapy Leader Jim Wilson Talks Safety”

Evicted from the Smart City: No Citizens Needed

Tech vendors know when they knock on the doors of local politicians to pitch smart cities technologies and promising billions in savings, they are going to find a receptive audience. Big Tech promises what politicians desperately want to hear: that we can address deep-seated, structural urban problems through business-led technological innovation and somehow sidestep the … Continue reading “Evicted from the Smart City: No Citizens Needed”

Xconomy Presents: Big Data Meets Big Biology

As advances in genome sequencing, biomedical diagnostics, neuroscience, and other fields generate more data than the human mind can take in, new software and computing tools are taking over, transforming life sciences and healthcare by improving odds, minimizing risks, and optimizing outcomes. San Diego has been embracing this convergence of Big Data and Big Biology, … Continue reading “Xconomy Presents: Big Data Meets Big Biology”

Here’s What I Made (Finally) With My Glowforge Laser Cutter

When I lifted the lid on the Glowforge laser cutter to reveal the family portrait engraved on a wooden jigsaw puzzle, it brought a smile to my face like few other tech products I’ve used before. This simple project—enabled by a very complex machine—was a long time coming, but it was worth the wait. I … Continue reading “Here’s What I Made (Finally) With My Glowforge Laser Cutter”

Genomatica, Pioneer in Bio-Chemicals, Working Now on Sustainable Biz

Genomatica, a San Diego industrial biotech, has spent the past 12 years or more working to take the petroleum part out of the petrochemical industry. In 2008, for example, Genomatica showed it had bio-engineered E. coli bacteria to digest sugar, oxygen, and other nutrients in a fermentation tank—and produce 1,4-butanediol (BDO), an intermediate chemical used … Continue reading “Genomatica, Pioneer in Bio-Chemicals, Working Now on Sustainable Biz”

Bio Roundup: Spark v. ICER, A Solid Revelation, T Cell Deals & More

The United States has a new Health and Human Services chief who is expected to weigh in on the country’s drug-pricing debate. But how Alex Azar, a former pharma executive at Eli Lilly (NYSE: [[ticker:LLY]]), plans to throw his weight around remains to be seen. One of the latest exhibits in the debate is an … Continue reading “Bio Roundup: Spark v. ICER, A Solid Revelation, T Cell Deals & More”

With Medical Records Tools, Apple Wades Deeper Into Digital Health

[Updated 1/24/18 4:09 p.m. See below.] Apple said Wednesday it plans to introduce new features that will allow iPhone users to access parts of their medical records through the company’s Health app. The move could impact the interoperability of health records software and spark more competition in the health IT industry. Cupertino, CA-based Apple (NASDAQ: … Continue reading “With Medical Records Tools, Apple Wades Deeper Into Digital Health”

SoftBank Continues Funding Spree, Leads $865M Round for Katerra

Katerra, a building construction startup inspired by the efficient practices of electronics manufacturing, announced today it has raised $865 million in a Series D fundraising round led by the SoftBank Vision Fund. The company was co-founded in 2015 by Michael Marks, the former CEO of contract electronics manufacturer Flextronics. Katerra has large-scale ambitions that match the … Continue reading “SoftBank Continues Funding Spree, Leads $865M Round for Katerra”

Should Startups Extend the Window to Exercise Options?

Pinterest did it. Square did it. And Coinbase did it, too. These unicorns have all given departing employees more than the standard 90 days to exercise their stock options. They’ve extended the window to exercise options for employees who have at least a minimum period of service. The tech recruiting site Triplebyte urged an even … Continue reading “Should Startups Extend the Window to Exercise Options?”

Facebook Touts Countermeasures to Election Hacking: Are They Enough?

Facebook expanded its mea culpa on Monday for failing to prevent “bad actors” such as Russian entities from using the social media platform to distort democratic processes—notably the U.S. presidential election in 2016. The company unveiled another series of measures it’s taking to prevent malefactors, who hide behind false names, from spreading fake and incendiary … Continue reading “Facebook Touts Countermeasures to Election Hacking: Are They Enough?”

Disney, Family Offices Back Second Bio Startup from Tech Entrepreneur Haney

To launch his first biotech startup, Dragonfly Therapeutics, Bill Haney went to private family offices, including one linked to the Disney family, rather than venture firms. Now the tech investor, entrepreneur and filmmaker is at it again, leaning on some of the same investors to fund Skyhawk Therapeutics, a new company joining an emerging race … Continue reading “Disney, Family Offices Back Second Bio Startup from Tech Entrepreneur Haney”

Hey Alexa, What’s in a Name? Actually, Let’s Call You Amazon

With “Hey Google” and “Alexa” echoing from the expo halls of Las Vegas to millions of homes, the hype around voice-controlled computing is reaching a new peak in early 2018. Voice-controlled devices are permeating our world, and this new user interface is the future of computing—or so we are told by the companies purveying it. … Continue reading “Hey Alexa, What’s in a Name? Actually, Let’s Call You Amazon”

Luna DNA Uses Blockchain to Share Genomic Data as a “Public Benefit”

A San Diego startup says it has adapted the blockchain technology that underpins digital currencies like Bitcoin for use as a distributed database for genomic information. Luna DNA’s efforts mark one of the early attempts to apply blockchain technology in healthcare, as advocates of the much-hyped technology try to make use of it in sectors … Continue reading “Luna DNA Uses Blockchain to Share Genomic Data as a “Public Benefit””

Why Spark and Watchdog ICER Don’t See Eye-to-Eye on $850K Gene Therapy

The first gene therapy approved in the U.S. costs $850,000. Announcing the price on Jan. 3, its owner Spark Therapeutics held out the possibility of some relief, such as installment payments, or slim rebates if the drug, a one-time shot into each eye to reduce or reverse inherited vision loss, doesn’t work or wears off. … Continue reading “Why Spark and Watchdog ICER Don’t See Eye-to-Eye on $850K Gene Therapy”

Democratization of Automation: The Next Generation of Industrial Robotics

In the coming years, artificial intelligence will have many transformative impacts, but the one perhaps most resembling science fiction will be the rise of autonomous physical systems: real-world systems that can make decisions for themselves. Of these autonomous systems, self-driving cars have captured the most attention. But the field of manufacturing, which represents one-sixth of … Continue reading “Democratization of Automation: The Next Generation of Industrial Robotics”

Eli Lilly’s Eiry Roberts Joins Neurocrine as Chief Medical Officer

Eiry Roberts is Neurocrine Biosciences’ (NASDAQ: [[ticker:NBIX]]) new chief medical officer. Roberts comes to the San Diego biotech company from Eli Lilly (NYSE: [[ticker:LLY]]), where her roles included serving as vice president of clinical pharmacology, and vice president of R&D in the company’s biomedicines business unit. Roberts succeeds Christopher O’Brien, who will retire in February. … Continue reading “Eli Lilly’s Eiry Roberts Joins Neurocrine as Chief Medical Officer”

Q&A: Dell Med’s DeSalvo Talks Social Health Startups, Data Ownership

Karen DeSalvo has experience working in the public sector, but she’s hardly what you’d call a government bureaucrat. DeSalvo, who is trained as a physician, served as the National Coordinator for Health Information Technology from 2014 to 2016 under President Barack Obama. During some of the time she headed the ONC, as the office is … Continue reading “Q&A: Dell Med’s DeSalvo Talks Social Health Startups, Data Ownership”

Bio Roundup: Spark’s Road Ahead, Juno Rumors, Merck’s Big Day & More

The most overblown health story of the week was President Trump’s health exam. America learned Trump is in perfect health and has “great genes.” He takes Propecia. He doesn’t have heart problems, had a perfect cognitive test score, and is one pound shy of obese. This scintillating information led to a new social media phenomenon, the … Continue reading “Bio Roundup: Spark’s Road Ahead, Juno Rumors, Merck’s Big Day & More”

Tougher “Immigration” Policies On Foreign Tech Crossing U.S. Border

It’s not only people from other countries that are struggling harder to get into the United States these days, it seems. Technology from foreign nations may also be subject to stricter “immigration” rules. The national origins of tech devices and services wasn’t a front-burner question—at least for the general public—until the issue came up at … Continue reading “Tougher “Immigration” Policies On Foreign Tech Crossing U.S. Border”

Absences, Surprises in Amazon’s Final List of 20 Cities for HQ2

And then there were 20. Amazon has winnowed down the field of 238 submissions from communities around North America vying to host a second headquarters (HQ2) of the Seattle-based tech giant. Most large cities with existing or emerging tech hubs appear on the list, from Austin, TX, and Boston, MA, to Washington, DC, and Toronto, … Continue reading “Absences, Surprises in Amazon’s Final List of 20 Cities for HQ2”

Detroit Auto Show Puts Big Focus on Mobility Technologies, Startups

The North American International Auto Show (NAIAS) kicked off this week in Detroit, allowing industry affiliates and media to get an early look before the show opens to the public this weekend. For the second year in a row, NAIAS highlighted the mobility sector’s potential business models and offered glimpses of how the trillion-dollar market … Continue reading “Detroit Auto Show Puts Big Focus on Mobility Technologies, Startups”