Klotho Therapeutics, a virtual biotech developing a kidney disease treatment based on its proprietary engineered version of the human klotho enzyme, said Thursday it has raised $10 million in Series A financing from San Diego’s Thynk Capital. Thynk Capital founder and principal Jim Plante also is Klotho’s founder and CEO. Plante is a technology industry … Continue reading “Klotho Therapeutics Raises $10M to Test Drug in Kidney Disease”
Category: San Diego
Biotech Roundup: Opioid News, ASH Preview, Boston Bio IPOs & More
The rising death toll from opioids has prompted policymakers to try various ways to take on the problem. President Trump’s opioid commission released its final report this week, calling for expansion of drug courts, better physician training, and penalties for insurers that don’t cover treatment. But the commission did not say how much its recommendations … Continue reading “Biotech Roundup: Opioid News, ASH Preview, Boston Bio IPOs & More”
Congress Urges Tech Firms to Control Content—But With Qualms
At Congressional hearings this week on Russia’s use of social media to interfere with the 2016 U.S. election, lawmakers pressed Facebook, Twitter, and Google to take exhaustive measures to stop the same thing from happening again. Lawmakers urged the companies to scour their networks to root out foreign advertisers, trolls, and bots; to eliminate messages … Continue reading “Congress Urges Tech Firms to Control Content—But With Qualms”
John Mendlein Passes Torch to New CEO at San Diego’s aTyr Pharma
San Diego-based aTyr Pharma (NASDAQ: [[ticker:LIFE]]) said John Mendlein is stepping down as president and CEO, effective today. According to a statement released after the market closed, Sanjay S. Shukla, who has served as aTyr’s chief medical officer since March 2016, is succeeding Mendlein, who plans to continue to serve on aTyr’s board as a … Continue reading “John Mendlein Passes Torch to New CEO at San Diego’s aTyr Pharma”
Few Opioid Alternatives In Sight as Crisis Gains Political Attention
As opioid-related deaths skyrocket across the U.S., momentum to combat the epidemic has been mounting in Washington. But the crisis has also highlighted a glaring problem that no amount of politics or policymaking will solve soon: The lack of non-addictive pain medicines. “What is disappointing over the last half-century is that we haven’t really created … Continue reading “Few Opioid Alternatives In Sight as Crisis Gains Political Attention”
ASH Sneak Peeks: Novartis, Juno Update CAR-T Lymphoma Competition
[Corrected, 11/1/17, 5:20 p.m. ET. See below.] The annual American Society of Hematology meeting is next month. But previews of the big data presentations are out today, yielding more insight into what promises to be the first major competition in CAR-T cell therapy: Treatments for people with non-Hodgkin lymphoma (NHL) who have run out of … Continue reading “ASH Sneak Peeks: Novartis, Juno Update CAR-T Lymphoma Competition”
As Facebook Fights Fake News, LeCun Sees Bigger Role for A.I.
As top lawyers from Facebook, Google, and Twitter testify on Capitol Hill this week about Russians using their platforms to interfere in the 2016 U.S. presidential election, it’s becoming clearer that the fight against the spread of fake news won’t be won by humans alone. That’s according to Yann LeCun, a machine learning expert and … Continue reading “As Facebook Fights Fake News, LeCun Sees Bigger Role for A.I.”
Techstars Sustainability Adds to Growth of Sponsored Accelerators
After Techstars opened its first program in Boulder, CO, in 2007, the startup accelerator program expanded into three cities over the next four years. But then the real growth started happening. In 2011, Techstars began launching accelerators that focused on startups innovating in a specific sector in partnership with big companies. It partnered with Nike … Continue reading “Techstars Sustainability Adds to Growth of Sponsored Accelerators”
New Survey Highlights “Lethargic Pace” of Healthcare Gender Equity
To close the healthcare and life sciences gender gap, there have been programs to move women into the boardroom. People are building mentoring networks. And there have been public pledges to do better. But women in the industry aren’t optimistic about big changes coming soon, according to a new report and survey from digital healthcare … Continue reading “New Survey Highlights “Lethargic Pace” of Healthcare Gender Equity”
As Russians Hacked U.S. Election, Did Big Tech Firms Break Any Laws?
News is constantly streaming out these days about the role of Facebook, Twitter, and Google in the 2016 presidential election; most disturbing to the public is the apparent use of social media, search, and video channels by Russian operatives seeking to influence U.S. voters. Critical lawmakers have blasted the big tech companies for failing to … Continue reading “As Russians Hacked U.S. Election, Did Big Tech Firms Break Any Laws?”
San Diego Positions Itself as Autonomous Technology Proving Ground
UC San Diego is becoming a test bed for self-driving vehicle technology. With a campus that encompasses more than 3.3 square miles and a daytime population of roughly 65,000, “It’s a small city,” said Henrik Christensen, who is leading the new project as director of the university’s Institute for Contextual Robotics. Christensen, who announced the … Continue reading “San Diego Positions Itself as Autonomous Technology Proving Ground”
Tocagen Adopts “Seamless Pivotal Trial” for Brain Cancer Therapy
Three-year survival rates are rarely reported for a deadly form of brain cancer known as recurrent, high-grade glioma (HGG). Under the current standard of care, the median survival rate is seven to nine months. Yet San Diego-based Tocagen (NASDAQ: [[ticker:TOCA]]) says five patients in a high-dose cohort of its gene therapy treatment Toca 511 and … Continue reading “Tocagen Adopts “Seamless Pivotal Trial” for Brain Cancer Therapy”
Bio Roundup: CBO’s Praise, Celgene’s Shock, Trump’s Opioid Plan & More
The White House and the FDA turned the spotlight on the nation’s opioid crisis. Blockbuster drugs from Alexion and Tesaro gained expanded approvals, but bad earnings news from Celgene and Biogen brought stocks down. Academics in the U.S. and China made progress with the gene editing technology CRISPR. And as the week’s biggest biotech deal … Continue reading “Bio Roundup: CBO’s Praise, Celgene’s Shock, Trump’s Opioid Plan & More”
Watch Out, VCs: A.I. Program Judges Startups at Boston Pitch Event
I rarely attend startup pitch competitions anymore. They’ve grown hackneyed over the past few years, thanks to a proliferation of such events and the popularity of the TV show “Shark Tank.” But a startup contest held Tuesday at a machine learning conference in Cambridge, MA, put a twist on the typical scenario: the startups were … Continue reading “Watch Out, VCs: A.I. Program Judges Startups at Boston Pitch Event”
Terminated Blood Cancer Drug Springs Back to Life at SD Biotech
A blood cancer drug resurrected by the scientist who helped discover the compound, and who shepherded it through years of R&D, got a shot in the arm today, in the form of a $90 million financing deal with New York’s Oberland Capital. The financing paves the way for San Diego’s Impact Biomedicines to move forward … Continue reading “Terminated Blood Cancer Drug Springs Back to Life at SD Biotech”
As Drugs Fail, Some Researchers Urge a Return to Alzheimer’s Roots
As the quest to find treatments for Alzheimer’s disease keeps crashing against rocks, a group of researchers in the field want their peers to pay more attention to the part of the brain where Alzheimer’s disease first wreaks havoc. A new paper from the researchers, published this month in the journal Alzheimer’s & Dementia, is … Continue reading “As Drugs Fail, Some Researchers Urge a Return to Alzheimer’s Roots”
Cord Cutting: How to Get High-Speed Internet Without Cable, 2017 Edition
Hey folks. If you’re thinking about breaking away from the cable monopolies and getting your data, music, and video in other ways, congratulations, I’m with you. I cut the cord back in 2009, and now millions of people are doing the same every year. With the growing interest in cord-cutting, you’d think it would be … Continue reading “Cord Cutting: How to Get High-Speed Internet Without Cable, 2017 Edition”
SmartDrive Raises Capital, Rolls Out Distracted Driving Technology
At the American Trucking Association Management Conference in Orlando, FL, this week, San Diego’s SmartDrive Systems announced that Michelin North America has led a new investment round in the company, though SmartDrive wouldn’t say how much it has raised. SmartDrive, founded in 2004, specializes in dashboard video cameras and related analytic technology to identify dangerous … Continue reading “SmartDrive Raises Capital, Rolls Out Distracted Driving Technology”
Xconomy Q&A: An Update with Arcturus Therapeutics CEO Joseph Payne
Things have been moving quickly in recent weeks for the San Diego RNA drug developer Arcturus Therapeutics. After initiating a reverse merger last month, Arcturus signed a research collaboration and worldwide licensing agreement with Janssen Pharmaceuticals, part of the Johnson & Johnson (NYSE: [[ticker:JNJ]]) family of companies. In a statement last week, Arcturus said it … Continue reading “Xconomy Q&A: An Update with Arcturus Therapeutics CEO Joseph Payne”
Back to the (Near) Future: Join Us for San Diego Life Sciences 2022
In 2010, Xconomy convened “San Diego Life Sciences 2030,” a séance with the soothsayers of San Diego as they gazed into the future at what the local life sciences landscape might look like 20 years from now. This December, we are gathering some visionaries from the past and present for another look into the future—only … Continue reading “Back to the (Near) Future: Join Us for San Diego Life Sciences 2022”
Bio Roundup: Kite’s CAR-T Approved, Obamacare Fix & Lilly mRNA Deal
Kite Pharma wasn’t expecting a regulatory decision for its non-Hodgkin lymphoma treatment until November, but this week, the company got the FDA’s O.K. The approval of axicabtagene ciloleucel (Yescarta) marks the second time in the two months that the FDA has given the nod to a CAR-T therapy, a treatment made from a patient’s own … Continue reading “Bio Roundup: Kite’s CAR-T Approved, Obamacare Fix & Lilly mRNA Deal”
Level Playing Field? How Big Company Dominance May Hinder Innovation
The conventional wisdom about Silicon Valley is that it’s a playground for the underdogs, a fertile ground for young entrepreneurs building startups that are going to “change the world.” Instead, the Bay Area—while, yes, still home to thirsty young entrepreneurs—is increasingly the stomping grounds of a few major tech companies that have come to dominate … Continue reading “Level Playing Field? How Big Company Dominance May Hinder Innovation”
With Pitches for HQ2 Made, Cities Wait on Amazon’s 2018 Decision
From Portland to Pittsburgh, it’s likely that every city in the U.S. with more than 1 million people has made its case to Amazon to locate the company’s second headquarters there. At least, hopefully they have already, because today—if you haven’t heard—was the deadline to apply. Amazon sent North America into a frenzy after announcing … Continue reading “With Pitches for HQ2 Made, Cities Wait on Amazon’s 2018 Decision”
Xconomy EXOME Presents: San Diego Life Sciences 2022
In 2010, Xconomy San Diego assembled a panel of biotech visionaries to peer over the horizon and predict what the local life sciences landscape would look like in 2030. But consider how much has changed since 2010 just in the fields of immunotherapy, genomics, and precision medicine. Among San Diego’s big companies, Illumina has literally … Continue reading “Xconomy EXOME Presents: San Diego Life Sciences 2022”
Lab Focused on Human-Centered Design Moves to Put San Diego on Map
For Michèle Morris, the big question hanging over organizers as they laid the groundwork last year for the first Design Forward Summit was whether the innovation community in San Diego understood the value of design. “We didn’t know who was going to show up—and 600 people showed up,” said Morris, who is associate director of … Continue reading “Lab Focused on Human-Centered Design Moves to Put San Diego on Map”
Kite Nabs First Adult CAR-T Approval With Notable Uptick Of Cures
For the second time in two months, remarkable recoveries from desperate cases of cancer have led to early approval of a cutting-edge therapy called CAR-T, which is made from a patient’s own genetically engineered cells. More than a month before the decision was due, the FDA has given the nod to axicabtagene ciloleucel, now branded … Continue reading “Kite Nabs First Adult CAR-T Approval With Notable Uptick Of Cures”
After Trump Sounds Off, Senate Has Adult Conversation on Drug Prices
In advance of an anticipated Senate hearing on drug prices, President Donald Trump once again denounced drug companies as “getting away with murder.” The first time he did so, using the same phrase just before his inauguration, the markets shuddered. He also said at the time that “we’re going to start bidding,” a reference to … Continue reading “After Trump Sounds Off, Senate Has Adult Conversation on Drug Prices”
Vinod Khosla on A.I., Health, and the Future of Working (or Not)
Entrepreneur-turned-venture capitalist Vinod Khosla made big headlines almost six years ago when he wrote a blog post called “Do We Need Doctors or Algorithms?” In it, he said medicine needed to be reinvented and he predicted a new era in which artificial intelligence might replace most of the functions that doctors do now—and do it … Continue reading “Vinod Khosla on A.I., Health, and the Future of Working (or Not)”
JLABS Takes Stock of Its Experiment in Life Sciences Innovation
What began as a kind of business experiment in innovation has acquired a life of its own. The idea in 2011 was to create a space at what was then Johnson & Johnson’s pharmaceutical research and development facility in San Diego for an “innovation center,” a place where 18 to 20 life sciences startups could … Continue reading “JLABS Takes Stock of Its Experiment in Life Sciences Innovation”
Bio Roundup: Light For Spark, California Drug Law, IPO Queue & More
In a year of tragedies across the U.S., natural or otherwise, it seemed this week was California’s turn. Fueled by high winds, low humidity, and ample dry vegetation, fires swept through several towns across the state and, as of this writing, have barely been contained. With our minds on friends and loved ones affected by … Continue reading “Bio Roundup: Light For Spark, California Drug Law, IPO Queue & More”
Xconomy Q&A: Security Sleuth Stefan Savage Wins MacArthur Grant
After winning a MacArthur “genius” grant late Tuesday, the San Diego cybersecurity sleuth Stefan Savage acknowledged the honor “definitely triggers my imposter syndrome.” Savage, a computer scientist at UC San Diego (and a San Diego Xconomist), added in an e-mail Wednesday, “It’s very nice to see all the work that I and my collaborators and … Continue reading “Xconomy Q&A: Security Sleuth Stefan Savage Wins MacArthur Grant”
Android Founder on VR, Voice & the Future of Human-Machine Collaboration
Within 20 years, computer keyboards will be relegated to the technology dustbin, says Android co-founder Rich Miner. Miner helped shape the smartphone era with Android, a mobile operating system startup that Google acquired in 2005. Android software now powers over 2 billion devices. On Tuesday, Miner spoke at a mobile software developer conference in Boston … Continue reading “Android Founder on VR, Voice & the Future of Human-Machine Collaboration”
San Diego VC Funding at $426.5M in Third Quarter; Plus Top 10 Deals
The San Diego artificial intelligence company Brain Corp. topped the chart for raising the most venture capital in San Diego during the third quarter that ended September 30, according to Venture Monitor data released Tuesday. As Xconomy reported in July, Brain Corp. raised $114 million in a Series C funding round led by Softbank’s new … Continue reading “San Diego VC Funding at $426.5M in Third Quarter; Plus Top 10 Deals”
Mapbox, Bill.com, Standard Cognition, Empowered by New Cash
—Mapbox announced Tuesday it had raised a hefty $164 million in a Series C financing round led by the SoftBank Vision Fund, which was joined by Foundry Group, DFJ Growth, DBL, and Thrive. The new capital will speed up Mapbox’s progress in vehicle navigation and autonomous driving, enlarge its virtual reality and augmented reality gaming capabilities, and fund its … Continue reading “Mapbox, Bill.com, Standard Cognition, Empowered by New Cash”
FDA To Advisors: What If One-Time Gene Therapy Needs Extra Doses?
In the run-up to a key vote on an experimental gene therapy, the FDA raised no major flags about the drug’s track record but said its long-term effect remains an open question. That question should receive a thorough airing Thursday, when a meeting of FDA outside advisors will weigh a recommendation of the one-shot gene … Continue reading “FDA To Advisors: What If One-Time Gene Therapy Needs Extra Doses?”
Black Fellowship Students Headed From HBCUs to VC Boardrooms
In mid-October, eleven college students will be flying to California for an opportunity that would be the envy of any Ivy League MBA candidate—they’ll meet the venture capital firm partners who will personally mentor them throughout the school year. The students—all but one are undergraduates—come from campuses in Prairie View, Texas; Tallahassee, Florida; and Nashville, … Continue reading “Black Fellowship Students Headed From HBCUs to VC Boardrooms”
VC Funding Surges in Fewer Deals in Third Quarter, and Top 10 Deals
[Updated 10/11/17, 12:25 am. See below.] “More dollars, fewer deals” has been a prevailing trend in venture funding over the past couple of years, and it was evident again in the three months that ended September 30, according to the latest Venture Monitor report. Venture firms invested $21.5 billion in 1,699 startups nationwide during the … Continue reading “VC Funding Surges in Fewer Deals in Third Quarter, and Top 10 Deals”
Blockchain, Banks & the New Web: Q&A With Ethereum Co-founder Lubin
Ethereum co-founder Joe Lubin is calm and soft-spoken when he shares his vision of how blockchain technology and digital currencies could transform the Internet, the global economy, and many aspects of our daily lives. But what he’s talking about could become a raging tempest, and it’s worth paying attention to—especially given the vast sums of … Continue reading “Blockchain, Banks & the New Web: Q&A With Ethereum Co-founder Lubin”
Steve Case’s Rise of the Rest Shines Spotlight on Emerging Tech Hubs
Steve Case, venture capitalist, author, and co-founder of AOL, is preparing to hit the road this week on his sixth Rise of the Rest tour, where he travels to emerging innovation hubs in search of investment-worthy tech startups and to highlight the growth happening outside of places like Silicon Valley and Boston. In the years … Continue reading “Steve Case’s Rise of the Rest Shines Spotlight on Emerging Tech Hubs”
San Diego Startup Uses Algae Feedstock to Make Renewable Flip-Flops
Every year, petroleum-based feedstocks are used worldwide to make roughly 3 billion flip-flops, the rubbery, flat-sole sandals held on the foot by a Y-shaped strap that fits between the first and second toes. It might seem like a throwaway product—and it is, according to Stephen Mayfield, a UC San Diego professor of biology and director … Continue reading “San Diego Startup Uses Algae Feedstock to Make Renewable Flip-Flops”
Bio Roundup: Nobel Pursuit, Fundraising Fruit, A Rhythmic IPO & More
The 2017 Nobel Prizes with a biomedical bent were announced this week. Three researchers shared the physiology and medicine prize for their work shining light on the circadian rhythms that govern the wake-and-sleep cycles of all organisms. That basic research is working its way into applications such as drugs that help regulate our body clocks. … Continue reading “Bio Roundup: Nobel Pursuit, Fundraising Fruit, A Rhythmic IPO & More”
Under New Ownership, San Diego’s Ad-Juster Names Dennis Clerke CEO
Ad-Juster, a San Diego adtech startup acquired earlier this year by the investment arm of China’s Innotech International Group, Wednesday named local software entrepreneur Dennis Clerke as CEO. He succeeds Ad-Juster founder and president Mike Lewis, who has left the company. Clerke (a San Diego Xconomist) was previously the CEO of Sunnyvale, CA-based NetSeer, an … Continue reading “Under New Ownership, San Diego’s Ad-Juster Names Dennis Clerke CEO”
AltspaceVR Finds New Home in Microsoft’s Mixed Reality Ecosystem
AltspaceVR, one of the forerunners of shared social experiences in virtual reality spaces, has been saved from extinction by Microsoft, which announced Tuesday that it is acquiring the four-year-old company. The Redwood City, CA-based startup had sounded its own death knell on July 28, announcing that it planned to shut down Aug. 3 due to the … Continue reading “AltspaceVR Finds New Home in Microsoft’s Mixed Reality Ecosystem”
Celebrating Boston Life Sciences: Xconomy Awards Gala Slideshow
We at Xconomy were thrilled to see such a great turnout at our first-ever Awards Gala—350 people from the Boston life sciences community filled a Hynes Convention Center ballroom. As Bob Buderi, our founder and editor-in-chief, said in his opening remarks on September 26 before a sold-out crowd: We clearly struck a chord. Top scientists, … Continue reading “Celebrating Boston Life Sciences: Xconomy Awards Gala Slideshow”
ServiceNow Buys San Diego Specialist in Customer Experience, Design
[Clarified 10/10/17, 11:15 am. See below.] ServiceNow (NYSE: [[ticker:NOW]]), the Santa Clara, CA-based giant that provides cloud-based IT services, is boosting its emphasis on human-centered design with its acquisition of Telepathy, a San Diego specialist in customer experience and design. Financial terms of the deal were not disclosed. “ServiceNow chose us because of the design … Continue reading “ServiceNow Buys San Diego Specialist in Customer Experience, Design”
Wind Startup Evokes Puerto Rico’s Plight, Wins EvoNexus Pitch Event
San Diego’s Uprise Energy won the audience vote for best presentation at EvoNexus Demo Day, with a pitch that highlighted how its mobile wind turbines could help alleviate the plight of Puerto Rico in the wake of Hurricane Maria’s apocalyptic devastation. The startup event drew more than 400 people to Qualcomm’s San Diego headquarters late … Continue reading “Wind Startup Evokes Puerto Rico’s Plight, Wins EvoNexus Pitch Event”
Twitter Joins Facebook in Political Hot Seat Over Election Hacking
Ordinarily, Twitter’s announcement that some of its users can now send tweets twice as long as its signature 140-character limit, and that this freedom could be broadened to others, would have been the company’s top news of the week. But instead, Twitter, like Facebook before it, is under the national microscope as government investigations of … Continue reading “Twitter Joins Facebook in Political Hot Seat Over Election Hacking”
Bio Roundup: Graham-Cassidy, Axovant Fail, SpringWorks Launches & More
After drug pricing, count drug shortages among the hot button issues sparking patient ire. Last year, the FDA says, 23 drug shortages were reported, down from 26 the previous year (and 251 in 2011). But Hurricane Maria’s direct strike on Puerto Rico might put the progress made on reducing shortages to the test. The Pharmaceutical … Continue reading “Bio Roundup: Graham-Cassidy, Axovant Fail, SpringWorks Launches & More”
San Diego Meets the Xconomists: When Social Media Is Not Enough
The technology for online social networks arrived practically hand-in-hand with the Internet. Since the advent of the World Wide Web in the mid-1990s, we’ve seen such networks proliferate, from the Whole Earth ‘Lectronic Link (remember The WELL?) and chat rooms on Bulletin Board Systems to Yahoo message boards, LinkedIn, Myspace, Twitter, and Instagram. Nowadays, Facebook … Continue reading “San Diego Meets the Xconomists: When Social Media Is Not Enough”
Epic Seeks to Join Alexa, Siri as Software You Can Chat With
Epic Systems may soon add its name to the list of companies with virtual assistant software that people can give instructions to and get information from. But those who say, ‘Hey Epic’ to initiate a man-to-machine conversation won’t be your average consumers. Instead, they’ll be doctors, nurses, and others who use the Verona, WI-based company’s … Continue reading “Epic Seeks to Join Alexa, Siri as Software You Can Chat With”