The treatment landscape for multiple myeloma, a deadly cancer of the bone marrow that affects about 30,000 Americans every year, has changed significantly over the past decade. And more changes look to be on the way. Take the results of a Phase 3 study just reported today at the American Society of Hematology’s (ASH) yearly … Continue reading “BCMA Day: At ASH ‘18, Cell Therapies For Myeloma Take Center Stage”
Category: Seattle
Event-Stream Hack Is Not Cause For Panic About Open-Source Security
News last week that event-stream, the popular open-source code library managed by NPM, had been compromised by a hacker (or hackers) looking to steal Bitcoin led some to question the underlying security of the open-source components that they are using in their software. According to reports, a hacker gained control of the event-stream package by … Continue reading “Event-Stream Hack Is Not Cause For Panic About Open-Source Security”
15Five Lands $8M to Provide Coaching Software to More Managers
[Updated 12/4/18 9:20 am. See below.] San Francisco-based performance management startup 15Five, whose mission is to torpedo annual performance reviews for workers and replace them with supportive weekly coaching by managers, announced today it raised $8 million in a Series A funding round. 15Five gets its name from the feedback and coaching process that its … Continue reading “15Five Lands $8M to Provide Coaching Software to More Managers”
ASH 2018: Three Up, Two Down as Big Blood Disease Meeting Rolls On
[Updated 4:37 p.m. See below.] Last week, Xconomy previewed the American Society of Hematology’s big meeting in San Diego, the largest medical gathering in the country on blood diseases. We took a deep dive into five specific disease areas under scrutiny, from lymphoma to hemophilia to sickle cell disease and more. News related to those … Continue reading “ASH 2018: Three Up, Two Down as Big Blood Disease Meeting Rolls On”
Volvo Expands In Silicon Valley As Auto Innovation Goes West
As GM announced a wave of auto plant closures in the North American heartland this week at the cost of thousands of jobs, Sweden’s Volvo Cars was expanding its U.S. presence, both in Silicon Valley and at a new South Carolina factory. Like Detroit-based GM (NYSE: [[ticker:GM]]), which is shifting its attention from traditional auto manufacturing … Continue reading “Volvo Expands In Silicon Valley As Auto Innovation Goes West”
Made in Italy: MakersValley Connects Boutiques to Apparel Factories
Amid what seems like unlimited choices, a key way for retailers to stand out is to try to offer products no one else has. For a small boutique, that could be exclusive access to a bespoke clothing line, say, but creating and manufacturing one is typically cost-prohibitive except for the largest of retailers. Enter MakersValley. … Continue reading “Made in Italy: MakersValley Connects Boutiques to Apparel Factories”
Bio Roundup: CRISPR Babies, Blood Diseases, Big Cancer Nod & More
This was one of those weeks when the world seemed to slip into a new era with no going back. A Chinese researcher, He Jiankui, claimed he helped bring to life two genetically engineered babies, twin girls with a gene disabled to make them immune to HIV infection. Even though the technology He used—in vitro … Continue reading “Bio Roundup: CRISPR Babies, Blood Diseases, Big Cancer Nod & More”
GM’s Ammann Takes Reins of Cruise From Co-Founder Vogt, Now CTO
Self-driving car business Cruise has a new leader: Dan Ammann, the General Motors president who led the company’s acquisition of Cruise in 2016, is now being named CEO of the autonomous vehicle subsidiary. Cruise co-founder Kyle Vogt is relinquishing the top role to remain with the company as its president and chief technology officer. Vogt … Continue reading “GM’s Ammann Takes Reins of Cruise From Co-Founder Vogt, Now CTO”
Women Inspire NYC’s Tech Startups to Dream Bigger
As a native New Yorker, it may not come as much of a surprise that growing up I wanted to work in finance. In fact, I put myself through NYU Stern while working for companies like IBM, Prudential, and Merrill Lynch, and joined Goldman Sachs upon graduation. You could say I had made it in … Continue reading “Women Inspire NYC’s Tech Startups to Dream Bigger”
Amazon Wants to Help Doctors and Patients Process Healthcare Data
Amazon intends to wade deeper into healthcare. The company announced Tuesday that it is working with groups in the industry to help them make sense of unstructured medical data using Amazon’s software tools. The Seattle e-commerce and technology giant unveiled what it calls Amazon Comprehend Medical, which the company says could help hospitals, clinics, and … Continue reading “Amazon Wants to Help Doctors and Patients Process Healthcare Data”
Under Fire, He Jiankui Says He’s “Proud” to Help Make CRISPR’d Babies
[Updated, 11/28/18, 12:20pm ET. See below.] Is there another CRISPR baby on the way? In his first public appearance since his stunning claim, released on YouTube Sunday, that he helped bring the first genome-edited humans into the world, He Jiankui, a genomics researcher at Southern University of Science and Technology of China in Shenzhen, said … Continue reading “Under Fire, He Jiankui Says He’s “Proud” to Help Make CRISPR’d Babies”
NY E-Commerce Startups Ponder a Future With Amazon “HQ2” in Backyard
As Amazon moves into its new home in the Big Apple, the company will find itself immersed in a storied—if tumultuous—local retail industry. Unlike the other contenders for Amazon’s so-called “HQ2” satellite offices, New York City is home to the nation’s historical retail roots on “Fashion Avenue,” as well as a growing e-commerce startup scene. … Continue reading “NY E-Commerce Startups Ponder a Future With Amazon “HQ2” in Backyard”
Genetic Medicine: FDA OKs 2nd Cancer Drug That Targets DNA, Not Tissues
[Updated 11/26/18. See below.] Going deeper into the new world of genetic medicine, the FDA has for the second time approved a drug that targets a tumor’s DNA fingerprint, no matter where in the body that cancer is found. And more could be on the way. The drug is larotrectinib (Vitrakvi), from Loxo Oncology (NASDAQ: … Continue reading “Genetic Medicine: FDA OKs 2nd Cancer Drug That Targets DNA, Not Tissues”
Necessity Vs. Innovation-Based Entrepreneurs
What makes someone an entrepreneur? Most simply defined, an entrepreneur is a person who identifies a need and starts a business to fill that void. But others will argue that a “true” entrepreneur must come up with an innovative new product or service and then operates their business to sell and profit from that innovation. … Continue reading “Necessity Vs. Innovation-Based Entrepreneurs”
ASH 2018: A Guide to the Latest for Blood-Borne Cancers and More
[Note: Ben Fidler co-authored this report.] This weekend, San Diego will host the annual American Society of Hematology conference, the largest U.S. medical gathering to get the latest on blood diseases, and a venue for updates on some of the most cutting-edge biotechnologies that only a few years ago seemed like science fiction. Using the … Continue reading “ASH 2018: A Guide to the Latest for Blood-Borne Cancers and More”
Benjamin Harshbarger Steps In as Interim CEO at Novelion
Novelion Therapeutics (NASDAQ: [[ticker:NVLN]]) has appointed Benjamin Harshbarger interim CEO. Harshbarger had been general counsel for the Vancouver, BC-based company for the past two years. He is taking the place of Jeffrey Hackman, who Novelion says has resigned as interim CEO to pursue another opportunity. The company added that Hackman will remain with the company … Continue reading “Benjamin Harshbarger Steps In as Interim CEO at Novelion”
Immigrants Are Key to Winning the AI Arms Race
If we want to create jobs and economic opportunity here in the U.S., we’re going to need immigrants. Not only have they pioneered our country’s greatest achievements, bringing you everything from hot dogs to YouTube, but today they serve at the cutting edge of our foremost industries. Nowhere is this more true than in the … Continue reading “Immigrants Are Key to Winning the AI Arms Race”
How Blockchain Is Finding a Place at Your Thanksgiving Table
The food we buy in grocery stores and restaurants has a story to tell about where it came from and each step it took on its journey to your dinner table. Blockchain technology can help tell that tale. The story many food companies want to tell these days is about safety. Earlier this year, an … Continue reading “How Blockchain Is Finding a Place at Your Thanksgiving Table”
Uber Expands Its E-Bike Service, Jump, to 2 More West Coast Cities
Hundreds of red, “dockless” electronic bikes appeared on the streets of San Diego and Seattle on Monday, the latest cities in which Uber introduced its e-bike program, Jump. The expansion comes days after Uber began rolling out the bike-sharing service across Los Angeles. The San Francisco-based ride-hailing giant acquired Jump Bikes, a Brooklyn e-bike sharing … Continue reading “Uber Expands Its E-Bike Service, Jump, to 2 More West Coast Cities”
Plant-Based Burger Maker Beyond Meat Cooks Up Plans for an IPO
We’ll soon find out if Wall Street has the appetite for investing in alternative meat technology. Beyond Meat, a maker of plant-based meat products, has filed for an IPO. The El Segundo, CA-based company set a preliminary target of $100 million for the stock offering, a figure that will likely change as the company moves … Continue reading “Plant-Based Burger Maker Beyond Meat Cooks Up Plans for an IPO”
X·CON 2018: Photos From Three Innovation Days in November
On November 4-6, Xconomy organized a meeting of the minds—an elite gathering of leaders in technology, business, healthcare, education, and energy—to discuss and demonstrate the key trends in their fields, heading into next year. Our expert speakers and attendees at X·CON 2018 tackled everything from the impact of artificial intelligence on enterprises to the emerging … Continue reading “X·CON 2018: Photos From Three Innovation Days in November”
Human Space Travel as a Platform to Accelerate Biomedical Innovation
A manned mission to Mars is slated for as early as 2024, but there are serious health risks that must be mitigated in order for such a mission to be successful. The most pressing risk identified by NASA is radiation exposure. Instead of stunting our spirit of exploration, there is an urgent need to develop effective radioprotection strategies to … Continue reading “Human Space Travel as a Platform to Accelerate Biomedical Innovation”
Wonolo Scores $32M to Expand Blue-Collar Gig Workers’ Marketplace
Wonolo, which runs a marketplace where companies can find fill-in staffers for jobs like stocking store shelves and warehouse chores, announced Monday that it raised $32 million in a Series C funding round led by Bain Capital Ventures. Bain Capital also invested this year in another tech startup focused on blue collar workers: UpKeep, which … Continue reading “Wonolo Scores $32M to Expand Blue-Collar Gig Workers’ Marketplace”
Bio Roundup: Moderna’s IPO, Arena’s Comeback, E-Cig Survey & More
Thanksgiving is around the corner and this week delivered a bounty of deals that have a number of life science companies expressing their thanks a little early. One deal saw a company land a whopping $800 million upfront for a rights to a drug still in clinical testing. Another biotech landed a $98 million investment … Continue reading “Bio Roundup: Moderna’s IPO, Arena’s Comeback, E-Cig Survey & More”
Silicon Valley Advisory: Make Talent Retention Personal
It took me by complete surprise. Here I was thinking we were on the same page, that we were doing some good things together and, despite some challenges, we made a pretty good team. So, when one of my brightest early talent employees walked into my office to tell me he was leaving, I asked … Continue reading “Silicon Valley Advisory: Make Talent Retention Personal”
Shyft Raises $6.5M for Staffing Tools Used by Workers and Employers
Shyft Technologies, a Seattle-based startup that has developed a software platform for retail and hospitality workers, and their employers, says it has raised $6.5 million in new funding to further develop its product. Two venture capital firms based in the Seattle area, Ignition Partners and Madrona Venture Group, led the Series A round, Shyft says. … Continue reading “Shyft Raises $6.5M for Staffing Tools Used by Workers and Employers”
Innovative Approaches to Homelessness in Seattle
The Pacific Science Center has a new exhibit called “Block by BLOCK: Innovating from the Ground Up,” highlighting the BLOCK project, a unique approach to the homelessness crisis in Seattle. The organization builds small homes that are completely off-grid and self-sufficient, and designed with functional amenities for people experiencing homelessness. But what really sets the … Continue reading “Innovative Approaches to Homelessness in Seattle”
No HQ2? No Problem, Say Leaders in TX Cities Passed Over by Amazon
As word trickled out that North Texas was likely one of three finalists for Amazon’s “HQ2,” Chris Wallace felt optimistic about the region’s prospects. After all, the tech giant had said its priorities included a skilled workforce, logistics infrastructure, and a competitive cost of living. Wallace, who is the president and CEO of the North … Continue reading “No HQ2? No Problem, Say Leaders in TX Cities Passed Over by Amazon”
Amazon Ends “HQ” Search, Pledges to Spend $5B on New Sites in NY, VA
The wait is finally over. Amazon said Tuesday it plans to significantly expand its presence in the New York City and Washington, DC, metropolitan areas beginning next year. The announcement was widely expected following news reports identifying the locales as likely winners of Amazon’s lengthy search process for an additional “headquarters,” as the company is … Continue reading “Amazon Ends “HQ” Search, Pledges to Spend $5B on New Sites in NY, VA”
CEOs and Scientific Founders: Tips for a Long and Successful Marriage
It seemed like the perfect match: A scientist founder from a top-tier academic institution; A technological innovation based on years and millions of dollars of federally-funded research in a university lab; And a successful entrepreneur and industry veteran named as the CEO of the startup that would take the work forward. But soon after the … Continue reading “CEOs and Scientific Founders: Tips for a Long and Successful Marriage”
Apptio Sells to PE Firm Vista Equity for $1.94B Two Years After IPO
Apptio is being taken private by investment firm Vista Equity Partners in a $1.94 billion acquisition. Founded in Bellevue, WA, in 2007, Apptio (NASDAQ: [[ticker:APTI]]) helps corporate leaders track and manage IT spending. The company went public in 2016 with a $96 million IPO, and has recently been acquiring other businesses. It bought FittedCloud, a … Continue reading “Apptio Sells to PE Firm Vista Equity for $1.94B Two Years After IPO”
Qualtrics Skips IPO for $8B Sale to SAP
It’s hard to say no to $8 billion. Qualtrics, the enterprise software firm that was on the verge of going public, has pulled its IPO in favor of selling to German software giant SAP for $8 billion in cash. Qualtrics—which has dual headquarters in Provo, Utah (where it was founded in 2002), and Seattle—sells software … Continue reading “Qualtrics Skips IPO for $8B Sale to SAP”
Bio Roundup: Midterm Fallout, Alzheimer’s Search, Postpartum Panel
There was plenty at stake in this week’s midterm elections, and not just in terms of political wins and losses. With congress now divided—Democrats took back control of the House and Republicans extended their majority in the Senate—the implications are significant for U.S. healthcare. Just a day after the results, for instance, Senate Majority Leader … Continue reading “Bio Roundup: Midterm Fallout, Alzheimer’s Search, Postpartum Panel”
Allergan’s Ellen Lubman Joins Impel NeuroPharma’s C-Suite
Impel NeuroPharma has appointed Ellen Lubman to serve as its chief business officer. Lubman comes to the Seattle biotech from Allergan (NYSE: [[ticker:AGN]]), where she was vice president of external science and innovation. Impel develops drugs that can be delivered through the nose to the brain. The company’s lead drug, INP104, is in late-stage testing … Continue reading “Allergan’s Ellen Lubman Joins Impel NeuroPharma’s C-Suite”
Hold Your Horsepower: For Mobility Industry, “Reality Is Sinking In”
Earlier this month, GM CEO Mary Barra told the crowd at a financial conference that her company was on track to unveil a ridesharing service in 2019 that would be powered by autonomous vehicles. It sounded like pretty big news, but to understand company announcements about the commercial viability of driverless cars, one must first … Continue reading “Hold Your Horsepower: For Mobility Industry, “Reality Is Sinking In””
Amazon Reportedly Picks HQ2 City—and, in Surprise, Another for HQ3
Amazon is reportedly choosing two cities, not one, for its second headquarters, according to sources cited by The Wall Street Journal and The New York Times. Amazon (NASDAQ: [[ticker:AMZN]]) is working on a deal to move into both the Long Island City neighborhood of Queens in New York City and the Crystal City neighborhood of … Continue reading “Amazon Reportedly Picks HQ2 City—and, in Surprise, Another for HQ3”
Esperanto Reaps $58M to Speed Development of Its AI Chip
Esperanto Technologies, a startup AI chip developer that has operated mostly below the radar since its founding in 2014, announced this week that it raised $58 million in a Series B fundraising round. Mountain View, CA-based Esperanto is vying with a host of competitors to create new processors for high-order tasks like machine learning and … Continue reading “Esperanto Reaps $58M to Speed Development of Its AI Chip”
Win $2 Million to Solve Alzheimer’s: New Prize Will Reward Fresh Ideas
San Antonio — A Texas billionaire is funding a new competition that will give $4 million to seven individuals who present promising ideas about the cause of Alzheimer’s disease and say they’ll work to prove it. Called the Oskar Fischer Project, the program will give the grand prize winner $2 million of the total, while two … Continue reading “Win $2 Million to Solve Alzheimer’s: New Prize Will Reward Fresh Ideas”
Bio Roundup: Depression Drug Dashed, Peek at ASH, CRISPR Worry & More
The gene-editing technology CRISPR-Cas9 is opening up new research avenues all the time, such as giving drug developers a cheaper, faster way to knock out genes in tumor cells. Studies of CRISPR-Cas9 to treat human disease are about to start, too. But will our immune systems, already on alert for common infections by the bacteria … Continue reading “Bio Roundup: Depression Drug Dashed, Peek at ASH, CRISPR Worry & More”
Cloud Leaders Shrug at IBM’s $34B Red Hat Deal
In some ways, the biggest software acquisition of all time could be a yawner. IBM’s planned $34 billion deal to acquire open-source software maker Red Hat is a hefty price to pay to give its cloud computing business a shot in the arm. But even if the purchase ultimately boosts IBM’s bottom line, some cloud … Continue reading “Cloud Leaders Shrug at IBM’s $34B Red Hat Deal”
IRobot’s Roombas to Map Households for Google Smart Homes
Autonomous vehicle developers rely heavily on navigational technology that maps the complex terrain of roads, curbs, signs, and people that their cars have to thread through. Google, as it develops its smart home systems, is turning to a company that already knows how to navigate the terrain of a household—corridors, kitchens, cat beds, cast-off shoes, … Continue reading “IRobot’s Roombas to Map Households for Google Smart Homes”
To Boost Cancer Pipeline, Gilead Bets at Least $50M on Startup Tango
Gilead Sciences is paying tiny Tango Therapeutics $50 million to tap into the startup’s cancer drug program, adding to what has been so far an expensive, but not yet lucrative, foray into cancer immunotherapy for Gilead. Cambridge, MA-based Tango is still in the early phases of looking for cancer drugs by exploiting a well-known tumor … Continue reading “To Boost Cancer Pipeline, Gilead Bets at Least $50M on Startup Tango”
Facebook’s 3Q Growth Suffices to Stave Off Another Stock Dive
Facebook (NASDAQ: [[ticker:FB]]) shares gained nearly 3 percent Tuesday, and ticked up further in after-hours trading following the release of a third quarter earnings report that showed some strengths as well as shortfalls. Investors have been concerned about the social media giant’s slowing growth rate in a year when it has been under scrutiny for … Continue reading “Facebook’s 3Q Growth Suffices to Stave Off Another Stock Dive”
Stantt CEO Thinks Its Approach to Selling Men’s Wear Fits Just Right
Stantt wants to make standard sizing anything but. “Traditional sizing only fits 15 percent of guys,” says Matt Hornbuckle, the startup’s founder and co-CEO. “Twins come in and get different sizes.” To connect guys with a shirt that fits well, the men’s wear startup created a database of “tens of thousands” of body scans. That … Continue reading “Stantt CEO Thinks Its Approach to Selling Men’s Wear Fits Just Right”
IBM Buying Red Hat in $34B Mega-Deal to Beat Amazon, Google in Cloud
[Updated 10/29/18, 12:53 pm, with executives’ comments.] IBM has agreed to buy open-source software maker Red Hat in a $34 billion bet aimed at helping it win the cloud computing war against Amazon, Microsoft, and Google. It’s one of the largest-ever U.S. tech acquisitions—the $67 billion Dell-EMC deal holds the top spot. Armonk, NY-based IBM … Continue reading “IBM Buying Red Hat in $34B Mega-Deal to Beat Amazon, Google in Cloud”
Pineapples and Bananas: Yummy to Eat, And Now Fashionable to Wear
Style trends may come and go but the apparel industry is increasingly accepting that sustainability will always be in fashion. “We have the chance to shift the environment to a cleaner, more non-toxic place,” says Greg Altman, co-founder and CEO of Silk, a Boston-area maker of a proprietary liquid silk. “That’s really our goal.” To … Continue reading “Pineapples and Bananas: Yummy to Eat, And Now Fashionable to Wear”
U.K. Slaps Maximum Fine of $645,000 on Facebook for Privacy Violations
The U.K.’s data privacy regulator fined Facebook $645,000 for violations that allowed political marketing firm Cambridge Analytica and other outside companies to extract 87 million Facebook profiles worldwide without adequate user knowledge or consent. The purpose of the U.K.’s enforcement actions is to change the behavior of organizations that mishandle the sensitive private information of … Continue reading “U.K. Slaps Maximum Fine of $645,000 on Facebook for Privacy Violations”
Bio Roundup: Alzheimer’s Puzzle, ESMO Assessed, Drug Prices & More
In the biotech investment and research communities this week, much of the attention was turned to Europe. Munich, Germany, hosted the annual conference of the European Society for Medical Oncology, where cancer drug developers unveiled the latest clinical data for experimental immunotherapies and drugs that treat the disease based on a tumor’s genetic signature. Also … Continue reading “Bio Roundup: Alzheimer’s Puzzle, ESMO Assessed, Drug Prices & More”
Trump Plan Ties Medicare Drug Prices to Cheaper Foreign Ones
[Updated 5:41pm ET with analyst note, see below.] When the Trump administration announced its blueprint for lowering prescription drug prices in May, many observers said it was too soft on the biopharma industry and didn’t contain concrete initiatives that could truly cut costs. But with the U.S. midterm elections fast approaching and the high cost … Continue reading “Trump Plan Ties Medicare Drug Prices to Cheaper Foreign Ones”
Berkeley’s SkyDeck Offers Chip Design Support Worth Millions to Startups
The current land rush in chip development, spurred as new technologies such as artificial intelligence create new needs, is pitting established semiconductor companies like Intel and Nvidia against tech titans like Facebook that are building their own chips. A wave of next-generation chip companies has also entered the fray. So how much room remains for … Continue reading “Berkeley’s SkyDeck Offers Chip Design Support Worth Millions to Startups”