Amgen Slashes Cholesterol Drug Price 60% to Match Rival Regeneron

[Updated, 10/25/18, 12:15 a.m. See below.] Amgen is cutting the list price of its new cholesterol-lowering drug by nearly 60 percent, a move the company says is intended to make the product more affordable for more patients. The move is a shot across the bow of Regeneron Pharmaceuticals (NASDAQ: [[ticker:REGN]]]). The Tarrytown, NY firm recently … Continue reading “Amgen Slashes Cholesterol Drug Price 60% to Match Rival Regeneron”

Baubles & Bling: Swoonery Uses Tech to Connect Shoppers With Jewelry

Jean Poh’s family has been in the jewelry business for four generations. And, for the most part, the industry has operated much the same as it always has, she says. Following a professional detour in which she worked as an attorney and angel investor, Poh made her way back to the jewelry business. She began … Continue reading “Baubles & Bling: Swoonery Uses Tech to Connect Shoppers With Jewelry”

ESMO ’18: Precision Meds, Breast, Lung, and More from the Cancer Front

[Ben Fidler co-authored this report.] The European Society for Medical Oncology is wrapping up its annual conference today, replete with clinical data from cancer’s front lines. We’ve sorted the headlines into a few big categories: immunotherapy combinations, breast cancer, lung cancer, the growing class of drugs called PARP inhibitors, and new drugs that treat tumors … Continue reading “ESMO ’18: Precision Meds, Breast, Lung, and More from the Cancer Front”

Why Technology Alone Won’t Fix Education

“Artificial intelligence will transform the education system.” “Immersive technology will reshape learning forever.” These are just some of the industry rumblings about how edtech will disrupt and ultimately “fix” what’s wrong with the education system in the United States. With back-to-school season in full swing, it’s imperative that we set the record straight. The truth … Continue reading “Why Technology Alone Won’t Fix Education”

Tech Industry Lobby Proposes Data Privacy Laws; Critics Call Them Weak

The tech industry, which reaps billions of dollars by harvesting personal data and using it to sell targeted advertising and other services, opened the door to federal data privacy regulations today in a proposal by ITI, a lobbying organization for tech companies. The Information Technology Industry Council, which represents the policy interests of companies including … Continue reading “Tech Industry Lobby Proposes Data Privacy Laws; Critics Call Them Weak”

Entrepreneurs Thinking Inside the Box

Hackathons usually involve thinking outside of the box. But for myself and four other MIT students, brainstorming, eating, and sleeping inside a 16-foot by 16-foot glass cube on campus for four days straight in mid-September proved just as effective at getting our creative juices flowing. The experience was part of InCube 2018, a global startup … Continue reading “Entrepreneurs Thinking Inside the Box”

Bio Roundup: Prices on TV, Novartis Hearts Radio, Warp Drive’s End

Two new battlegrounds emerged this week in the nation’s ongoing drug pricing debate. The first involved television: The federal government hopes that blaring prices in TV ads will essentially pressure drug makers into lowering them, and the pharma lobby fired back. The second centered around a group of pricey new migraine drugs: The nation’s largest … Continue reading “Bio Roundup: Prices on TV, Novartis Hearts Radio, Warp Drive’s End”

In Boston, Paul Allen Aimed to Boost Bioscience’s “Tempo of Discovery”

The scientific interests of the late Microsoft co-founder Paul Allen led him to fund a pair of major research centers in the Boston area devoted to cracking mysteries of the human biological code—and aiming to recreate the sort of foundational work he and Bill Gates applied to personal computing in the 1970s. Allen—who died Monday … Continue reading “In Boston, Paul Allen Aimed to Boost Bioscience’s “Tempo of Discovery””

Report: Express Scripts Shuts Out Teva Migraine Drug, Prefers Rivals

[Updated 10/17/18, 2:52 p.m. See below.] Express Scripts has just exerted its influence over the emerging market battle between drug makers trying to sell a new class of migraine-preventing medicines. The pharmacy benefits manager (PBM) is excluding a new drug from Teva Pharmaceutical from coverage while favoring two rival treatments instead, according to a report … Continue reading “Report: Express Scripts Shuts Out Teva Migraine Drug, Prefers Rivals”

SoftBank’s Arm to Include Cybereason Security Services in IoT Hub

Security-tech company Cybereason is announcing another boon flowing from close ties with its biggest investor, Japanese telecom and tech giant SoftBank. Boston-based Cybereason has formed a partnership with Arm, the dominant developer of computer chip architecture, which was acquired by SoftBank in 2016. Cybereason’s security services will be incorporated into the Arm Pelion IoT platform, a … Continue reading “SoftBank’s Arm to Include Cybereason Security Services in IoT Hub”

Citing Regulatory Uncertainty, Origin Code Academy to Close

Origin Code Academy, one of San Diego’s few coding schools—for-profit companies that offer short-term vocational training in computer programming—said this month it will shutter on Nov. 16 after about three years in business. The company opened in late 2015, offering a 12-week course for $13,500 and promising graduates a software job within 90 days of … Continue reading “Citing Regulatory Uncertainty, Origin Code Academy to Close”

Paul Allen’s Contributions, Far Beyond Microsoft, Touched the Brain, AI & More

Technology and life sciences leaders say they’ll remember Paul Allen, the Microsoft co-founder, philanthropist, and investor who passed away Monday at age 65, as an “inspiration” whose work will impact the fields he worked in for years to come. Allen died from complications of non-Hodgkin’s lymphoma, according to a statement from Vulcan, the Seattle-based philanthropy … Continue reading “Paul Allen’s Contributions, Far Beyond Microsoft, Touched the Brain, AI & More”

Tulerie Helps Users Dress Like Models, Without Breaking the Bank

Tulerie makes its debut today, joining a growing roster of online clothing rental startups. The New York-based Tulerie focuses on high-end couture—items that retail for $1,000 to $10,000—that might be worn a time or two but mostly take up space in a woman’s closet. The company is building a two-sided marketplace, with owners of haute … Continue reading “Tulerie Helps Users Dress Like Models, Without Breaking the Bank”

After Net Neutrality: How to Prepare for the Internet’s New Reality

The federal net neutrality regulation, which had guaranteed equal access to the Internet for data from all sources, is officially repealed. There are no longer federal rules ensuring that all Internet traffic must be treated equally, and no FCC protections to stop Internet Service Providers (ISPs) from engaging in blocking, throttling, or paid prioritization of … Continue reading “After Net Neutrality: How to Prepare for the Internet’s New Reality”

Room Service by Robot and Other Ways Tech Is Changing the Hotel Stay

More days than not, Michael Colaneri’s home is a hotel room. So innovations like “geolocation” sensors that automatically unlock his room door and adjust the thermostat when he’s nearby make the constant change easier—sometimes. “My experience has been exceptionally inconsistent,” he says. “When it’s worked, it’s really great, cool, and so efficient to the point … Continue reading “Room Service by Robot and Other Ways Tech Is Changing the Hotel Stay”

Bio Roundup: BIO Diversity, Allogene IPO, CRISPR In Utero & More

Nearly four years after investors snapped up new shares of Juno Therapeutics in a $265 million IPO, cancer immunotherapy remains a hot ticket. Like Juno, Allogene Therapeutics just pulled in a massive IPO haul, nearly $300 million. And like Juno, Allogene is working with a live immune-cell treatment called CAR-T, but it is harvesting cells … Continue reading “Bio Roundup: BIO Diversity, Allogene IPO, CRISPR In Utero & More”

Facebook Bars 800 Fake Accounts and Pages For Using Tactics Like Russia’s

In another wave of account shutdowns, Facebook announced Thursday that it disabled more than 800 pages and accounts to prevent groups that disguised their identities from flooding its network with inauthentic content—some of it hyper-partisan political messages. Facebook (NASDAQ: [[ticker:FB]]) has been under pressure to cleanse its pages of fake news since the discovery that … Continue reading “Facebook Bars 800 Fake Accounts and Pages For Using Tactics Like Russia’s”

BIO Has Big Diversity Goals. Does It Have the Means to Reach Them?

Whether from embarrassing parties or sobering surveys, the biotech gender gap problem has made plenty of headlines the past couple years. The industry’s largest trade group, the Biotechnology Industry Organization (BIO), is trying to encourage its more than 1,000 member companies to do better. Last winter, BIO posted diversity goals for the industry to hit … Continue reading “BIO Has Big Diversity Goals. Does It Have the Means to Reach Them?”

Tim Berners-Lee Building Inrupt to Fix the Web—Will Users Come?

The World Wide Web is at a crossroads. For all the benefits it has brought society over the past three decades—faster and easier communication, instant knowledge access, a seemingly inexhaustible marketplace of goods and services—the Web has also morphed into an “engine of inequity and division,” according to its inventor, Tim Berners-Lee (pictured above). In … Continue reading “Tim Berners-Lee Building Inrupt to Fix the Web—Will Users Come?”

Allogene’s IPO Raises $288M for Tests of “Off-the-Shelf” Cell Therapy

Allogene Therapeutics has raised $288 million in an IPO, marking one of the biggest stock market debuts for a biotech this year. The cell therapy developer sold 18.4 million shares at $18 apiece, within the high end of its projected $16 to $18 per share range. Shares of South San Francisco, CA-based Allogene are expected … Continue reading “Allogene’s IPO Raises $288M for Tests of “Off-the-Shelf” Cell Therapy”

Anaplan Ups Estimate For Its IPO Haul; Allogene IPO Raises $288M

San Francisco-based Anaplan, one of five companies planning to close initial public offerings this week, raised the expected price range for its shares in an SEC filing Wednesday, signaling an IPO that could be richer than it had anticipated. Enterprise planning software company Anaplan, which is privately valued at more than $1.4 billion, had originally … Continue reading “Anaplan Ups Estimate For Its IPO Haul; Allogene IPO Raises $288M”

U.S. Venture Capital Deals on Pace to Exceed $100B in 2018

Once considered a passing phase, the concentration of capital into fewer, larger venture capital deals appears to be the new normal. Fueled by so-called mega-funds, investment in U.S.-based venture-backed companies as of the end of the third quarter hit a decade high, and is on pace to pass the $100 billion mark by year’s end. … Continue reading “U.S. Venture Capital Deals on Pace to Exceed $100B in 2018”

With a $10.2M Boost, YourMechanic Aims at Mobility Fleet Market

Every month, there’s news of another partnership among carmakers like GM and tech companies such as Uber, as they vie for dominant roles in a transportation future where individual car ownership may largely give way to rides-on-demand from fleets of autonomous and tech-enabled vehicles. But whether Uber, Toyota, GM, Honda, or Google end up at … Continue reading “With a $10.2M Boost, YourMechanic Aims at Mobility Fleet Market”

Circulation CEO Talks Sale to LogistiCare & Amazon’s Healthcare Play

[Corrected 10/9/18, 10:09 am. See below.] The recent acquisition of Circulation, a software startup trying to make non-emergency medical transportation more efficient, could offer a glimpse of the next phase in the “consumerization” of healthcare—and, perhaps, another target market for Amazon. Those were some of the takeaways from a conversation I had Friday with Robin … Continue reading “Circulation CEO Talks Sale to LogistiCare & Amazon’s Healthcare Play”

Bio Roundup: Nobel Prizes, Duchenne Steps, Guardant’s IPO & More

Cancer immunotherapy is all the rage these days. The idea of harnessing the immune system to treat cancer has sparked billions of dollars in research, led to a vast matrix of clinical trials, and started to change the way how several cancers are treated. The reason: When it works, cancer immunotherapy can lead to longer-lasting … Continue reading “Bio Roundup: Nobel Prizes, Duchenne Steps, Guardant’s IPO & More”

Cloudera, Hortonworks Plan to Merge as $5.2B Cloud Data Platform

Cloudera and Hortonworks, two large, publicly traded companies that compete to offer Web-based data storage and analytics, announced plans today to merge into a combined entity they value at $5.2 billion. Share prices for the two Silicon Valley companies spiked in after-hours trading following the announcement Wednesday that both their boards approved the all-stock deal. Palo … Continue reading “Cloudera, Hortonworks Plan to Merge as $5.2B Cloud Data Platform”

Pfizer Veteran Bernard Fermini Joins Novoheart as Chief R&D Officer

Novoheart (TSXV: [[ticker:NVH]]) has appointed Bernard Fermini to serve as chief research and development officer of the Vancouver, BC, stem cell biotechnology company. Fermini most recently worked at Coyne Scientific, where he was vice president of safety and toxicology and chief scientific officer. His experience also includes 17 years at Pfizer (NYSE: [[ticker:PFE]]), where he … Continue reading “Pfizer Veteran Bernard Fermini Joins Novoheart as Chief R&D Officer”

Apptio Acquires FittedCloud to Broaden Enterprise IT Analytics Tools

Apptio, a Seattle-area company that helps corporate technology leaders manage their IT spending, said Wednesday that it has acquired FittedCloud, a Boston-based developer of cloud optimization software. Apptio’s (NASDAQ: [[ticker:APTI]]) news release announcing the deal did not contain any financial terms. However, the company said its acquisition of FittedCloud “is not material from a financial … Continue reading “Apptio Acquires FittedCloud to Broaden Enterprise IT Analytics Tools”

Girls In Tech Showcases Women Founders In SF Pitch Competition

Kristina Tsvetanova says she found the motivation for her startup Blitab in 2014, when a blind colleague’s struggle to communicate via the Internet made her conscious of the barriers facing visually impaired people in a digital world. Her search for solutions spurred her to move from her native Bulgaria to find greater resources in Vienna, … Continue reading “Girls In Tech Showcases Women Founders In SF Pitch Competition”

Pivot Bio Gets $70M, Led by Bill Gates’s Fund, to Replace Fertilizer

Applying fertilizers to fields has been a standard farming practice for generations. The problem with these chemicals is that they end up in the air or in water runoff. Scientists at agriculture startup Pivot Bio say the key to delivering an important nutrient to crops has been at the plants’ roots all along—and the company … Continue reading “Pivot Bio Gets $70M, Led by Bill Gates’s Fund, to Replace Fertilizer”

VelosBio Emerges with $58M in Funding to Steer Cancer Drugs to Clinic

VelosBio, a biotech startup researching new cancer drugs, has raised $58 million in financing. The new VelosBio cash, a Series A round of financing, was led by Arix Bioscience (LSE: [[ticker:ARIX]]) and Sofinnova Ventures. VelosBio joined Johnson & Johnson’s JLABS @ San Diego incubator in January. The company is developing antibody drug conjugates, a class … Continue reading “VelosBio Emerges with $58M in Funding to Steer Cancer Drugs to Clinic”

Findera Tries a Pivot Amid a Whirlwind Over Data Privacy Rules

Early last year, the San Francisco startup Yozio decided it would have to scuttle its core mission, despite having attracted marquee customers including Pinterest and Airbnb within only a few years. The problem was, there turned out to be too few such websites with the size and sophistication to use Yozio’s app-optimization tools to advantage, … Continue reading “Findera Tries a Pivot Amid a Whirlwind Over Data Privacy Rules”

XRC Labs Showcases Retail Tech Innovations in VR, AI, Big Data

XRC Labs, an accelerator program focused on e-commerce and retail startups, held a demo day for its latest class Thursday, featuring innovations in artificial intelligence, virtual reality, and other technologies. The group of 10 startups is the sixth class for New York-based XRC, which was founded three years ago to promote innovation in the disruptive … Continue reading “XRC Labs Showcases Retail Tech Innovations in VR, AI, Big Data”

Bio Roundup: Amarin’s Stunner, Lung Cancer News, Data Dumps & More

Six years ago, a biotech called Amarin won FDA approval of a prescription fish-oil pill, Vascepa, because it could lower triglycerides, a type of fat in the blood. But Amarin didn’t have the evidence that lowering triglycerides with fish oil would really help people. Sales lagged. Amarin’s shares sank. While other groups tested other fish … Continue reading “Bio Roundup: Amarin’s Stunner, Lung Cancer News, Data Dumps & More”

Six Life Science Firms Close Q3 with an IPO, More Are on the Way

The window for life science IPOs is still open, and five biotechs and one medical device company chose the last week of the third quarter to make their stock market debuts. Gritstone Oncology (NASDAQ: [[ticker:GRTS]]) closed out the week by raising $100 million in an upsized  IPO. On Thursday night, Emeryville, CA-based Gritstone priced its … Continue reading “Six Life Science Firms Close Q3 with an IPO, More Are on the Way”

Eli Lilly Strikes Deal for Diabetes Pill to Gain on Novo Nordisk

Eli Lilly has a blockbuster diabetes drug, dulaglutide (Trulicity), which helps the body make more insulin. But that drug, and others in the same class, are injectables. A number of companies are trying to offer patients a pill alternative. Lilly (NYSE: [[ticker:LLY]]) now has a new pill drug candidate in its pipeline. The Indianapolis pharmaceutical … Continue reading “Eli Lilly Strikes Deal for Diabetes Pill to Gain on Novo Nordisk”

Where Can Influential Companies Go to Meet Exceptional Black VCs?

Culture Shifting Weekend—a November 1-3 invitation-only summit, presented by Culture Shift Labs (CSL)—will offer a rare opportunity for leading companies and investors to meet, vet, and fund the fast-growing ecosystem of Black venture capitalists and VC firms. Hosted at Infor in New York City, Culture Shift Lab’s annual three-day event will enable institutional investors, social … Continue reading “Where Can Influential Companies Go to Meet Exceptional Black VCs?”

Blink Health Ramps Up in Boston as Amazon Eyes Prescription Drugs

A few months after Amazon announced a deal to acquire Boston-area online pharmacy startup PillPack, another healthcare technology venture is growing its presence here as it attempts to shake up the retail pharmacy industry. The newcomer is New York-based Blink Health, a four-year-old startup that enables people to buy low-cost prescription drugs online and pick … Continue reading “Blink Health Ramps Up in Boston as Amazon Eyes Prescription Drugs”

Former Kite Pharma Exec Anthony Polverino Named Zymeworks CSO

Anthony Polverino has been appointed executive vice president of early development and chief scientific officer of Vancouver, BC-based Zymeworks (NYSE: [[ticker:ZYME]]). Polverino most recently worked at Kite Pharma, where he was interim chief scientific officer, and prior to that, vice president of research. Kite was acquired by Gilead Sciences (NASDAQ: [[ticker:GILD]]) last year. Zymeworks develops … Continue reading “Former Kite Pharma Exec Anthony Polverino Named Zymeworks CSO”

How Groups Are Closing the Security Skills Gap, Boosting Diversity

Today, there is a massive shortage of cybersecurity talent across the globe. According to a 2015 study from Frost & Sullivan and the (ISC)² Foundation, there could be more than 1.5 million unfilled cybersecurity positions globally by 2020. As cybersecurity attacks and data breaches, unfortunately, become a matter of not if but when, security talent … Continue reading “How Groups Are Closing the Security Skills Gap, Boosting Diversity”

Adobe-Marketo Deal Could Spur Marketing Tech Tie-Ups, New Strategies

Marketo almost didn’t get off the ground. It was 2006, and Jon Miller and his Marketo co-founders were struggling to raise money from investors for their marketing technology startup. Their pitch was to use software to help businesses automate much of the process of tracking and managing the online sales leads they were getting from … Continue reading “Adobe-Marketo Deal Could Spur Marketing Tech Tie-Ups, New Strategies”

Packers, Microsoft Drop Accelerator Plans; TitleTownTech Still a Go

TitleTownTech, a soon-to-be-launched joint venture between the NFL’s Green Bay Packers and tech giant Microsoft, has hit the brakes on a startup accelerator the two organizations had previously said they planned to run together. Craig Dickman, whom the Packers named managing director of TitleTownTech earlier this week, says the goal of the joint venture—spurring digital-age … Continue reading “Packers, Microsoft Drop Accelerator Plans; TitleTownTech Still a Go”

Bio Roundup: Little Rhody, More for Migraine, Opioid Bills & More

The U.S. Senate had a rare moment of agreement, overwhelmingly passing a package of opioid-related bills. Up the East Coast, life-science players in Rhode Island are working to bring different local factions together and boost the state’s economy. Across the country, a similar effort is underway in Los Angeles. There were also plenty of headlines … Continue reading “Bio Roundup: Little Rhody, More for Migraine, Opioid Bills & More”

Convoy Reloads With $185M For Its Freight Shipment Marketplace

Convoy, an online marketplace that connects shippers with freight truck fleets and independent drivers, announced today it raised $185 million in a Series C fundraising round led by CapitalG, the growth equity investment fund of Alphabet, Google’s parent company. With its new funding, Seattle-based Convoy  plans to continue expanding its network of customers and truckers … Continue reading “Convoy Reloads With $185M For Its Freight Shipment Marketplace”

Rapid7 Launches Security Automation Tools to Take On IBM, FireEye

[Updated 9/20/18, 1:04 pm. See below.] Cybersecurity software firm Rapid7 is rolling out new and updated products geared toward helping customers automate more of their security processes and tie together the patchwork of defense mechanisms many of them have purchased from various vendors. The announcement fits into two big trends in security of the past … Continue reading “Rapid7 Launches Security Automation Tools to Take On IBM, FireEye”

Real Estate Startup Bungalo Launches with $225M, Could Land $1B More

Austin—An Austin real estate investment company has launched a buyer-focused, online residential home search business called Bungalo Technologies. Amherst, a business that uses data and analytics to invest billions of dollars into public securities and residential and commercial real estate, is launching Bungalo with $225 million in funding upfront, and says it will invest another … Continue reading “Real Estate Startup Bungalo Launches with $225M, Could Land $1B More”

In Boston’s Shadow, Rhode Island Fights for Life Science Jobs, Respect

[Updated 9/19/18, 3:40 p.m. See below.] Tiny Rhode Island and its capital city Providence have always punched above their weight, for better or for worse. Better: Little Rhody’s founder Roger Williams, fleeing religious persecution in 17th-century puritanical Massachusetts, was one of America’s first abolitionists and created the concept of the separation of church and state. … Continue reading “In Boston’s Shadow, Rhode Island Fights for Life Science Jobs, Respect”

UiPath Snags $225M To Expand Robotic Workforce for Businesses

Top venture capital firms continue to pour money into software robotics companies that promise to automate monotonous business operations, like processing mortgage applications, that are often performed by humans. New York-based UiPath is the latest such company to score a haul, announcing Tuesday it raised $225 million in a Series C funding round co-led by … Continue reading “UiPath Snags $225M To Expand Robotic Workforce for Businesses”

Google Leads Mabl’s $20M Series B as Software Testing Deals Heat Up

Dan Belcher and Izzy Azeri sold their last startup, Stackdriver, to Google. Now, Google’s venture capital arm has backed the entrepreneurial duo’s latest company, Mabl. Boston-based Mabl said Tuesday it has pulled in $20 million in a Series B funding round led by GV (formerly Google Ventures). CRV and Amplify Partners also contributed to the … Continue reading “Google Leads Mabl’s $20M Series B as Software Testing Deals Heat Up”

Teva Wins FDA Nod for Migraine Drug, Sets Price in Line with Amgen’s

A Teva Pharmaceutical migraine-prevention drug has won FDA approval, the second therapy in this new drug class to receive the regulatory nod this year. The Friday approval for the Teva (NYSE: [[ticker:TEVA]]) drug fremanezumab (Ajovy) came a little earlier than expected; the target date for the FDA decision was Sept. 16. The drug is part … Continue reading “Teva Wins FDA Nod for Migraine Drug, Sets Price in Line with Amgen’s”