[Updated, 12/13/17, 1:50 p.m. ET. See below.] The annual American Society of Hematology meeting is nearly over. For now, we’ve chosen updates from three disease areas to highlight, plus the more notable market movements. No surprise, there’s a lot about the genetically engineered cell therapy known as CAR-T. Gene therapy and more standard forms of … Continue reading “ASH 2017 Highlights: CAR-T Competition, Myeloma, Hemophilia & More”
Category: Seattle
After Raising $27M, Ouster to Plans Mass Manufacture of LiDAR Units
Light Detection and Ranging (LiDAR) is one of the most important technologies underpinning the development of driverless cars. LiDAR systems feed raw sensor data to the car’s brain, creating a 3D picture of the surrounding environment and enabling autonomous vehicles to navigate it. But LiDAR has also been controversial because it’s expensive, sometimes fallible, and … Continue reading “After Raising $27M, Ouster to Plans Mass Manufacture of LiDAR Units”
What Are the Nation’s Top Cities and Regions for Driverless Tech?
Whether you think self-driving cars are the stuff of science fiction or a potentially paradigm-shifting new form of transportation, autonomous vehicles are coming—and the companies developing them are spending big money to make it happen. A few years ago, industry analysts seemed to think Silicon Valley would win the race to get self-driving cars on … Continue reading “What Are the Nation’s Top Cities and Regions for Driverless Tech?”
Northwest Startup Supporters Grow U.S.-Canada Economic Ties
There’s a new network organizing the incubators, accelerators, and investors fostering innovation in the Pacific Northwest on both sides of the U.S.-Canada border. Business collaboration across the 49th parallel is having a moment, thanks in no small part to a dramatic divergence in immigration policies between the two countries this year that have prompted U.S. … Continue reading “Northwest Startup Supporters Grow U.S.-Canada Economic Ties”
Bio Roundup: Trials to Watch, Mega Deals, Video Game Therapy & More
With 2018 around the corner, this was a week to look ahead. At Xconomy, we zeroed in on several clinical trials that could become major stories in the life sciences. Other healthcare milestones are on the way, too. The FDA will consider for the first time whether a video game should be approved as medicine. … Continue reading “Bio Roundup: Trials to Watch, Mega Deals, Video Game Therapy & More”
The ‘Amazon Effect’ and the Gender Wage Gap
The battle to land Amazon’s second home is shaping up to be one of the fiercest competitions to lure a corporate headquarters in modern history. From serious incentives like massive tax breaks to headline grabbing stunts like offers of bear wrestling and giant cacti, it’s safe to say cities are pulling out every stop imaginable … Continue reading “The ‘Amazon Effect’ and the Gender Wage Gap”
Propose With a Lab-Made Diamond? Diamond Tech Retailers Say, “Yes”
How do you disrupt an industry that markets itself as the embodiment of “forever?” You bring it back to basics, says Lindsay Reinsmith, co-founder of Ada Diamonds, an online retailer of jewelry with lab-made gemstones in San Francisco. “Science is on our side,” she says. “We confront them with facts.” Machine-made gemstones are created in exactly … Continue reading “Propose With a Lab-Made Diamond? Diamond Tech Retailers Say, “Yes””
15 For ’18: Key Clinical Data to Watch For Next Year (Part 2)
[Corrected, 12/11/17, 1 p.m. ET. See below.] On Monday we posted the first part of our look at what should be some of 2018’s most important clinical data, including trials for lung cancer, heart disease, melanoma, Alzheimer’s disease, rare blood disorders, and more. With part two, we’re previewing studies for migraine, brain cancer, lymphoma, peanut … Continue reading “15 For ’18: Key Clinical Data to Watch For Next Year (Part 2)”
Gilman’s Next CEO Trick: Taming CAR-T Cells With Obsidian
Genetically modified medicine is here. Two CAR-T therapies, made from a patient’s living T cells, are on the market in the U.S., and many more are in various stages of clinical testing. As remarkable as they might seem, however, these medicines are still fairly crude, with no way to control them once inside a patient’s … Continue reading “Gilman’s Next CEO Trick: Taming CAR-T Cells With Obsidian”
Case’s $150M Rise of the Rest Fund Aims to Boost Flyover Startups
Author, investor, and AOL co-founder Steve Case today announced a new $150 million venture fund aimed at pumping investment capital into tech companies in so-called flyover states. Contributing to the fund is an impressive group of some of the most successful entrepreneurs in the country. Called the Rise of the Rest Seed Fund, it will … Continue reading “Case’s $150M Rise of the Rest Fund Aims to Boost Flyover Startups”
Black Venture Capitalists Are Transforming Tech
Would it surprise you to know that there are more than 100 black venture capitalists or that this nationwide ecosystem is growing? Most of the VCs in this expanding ecosystem made pivots from highly successful careers in other fields. They have very impressive academic credentials, business backgrounds comparable to their Silicon Valley peers, and a … Continue reading “Black Venture Capitalists Are Transforming Tech”
15 For ’18: Key Clinical Data to Watch For Next Year (Part 1)
Many of biotech’s biggest stories in 2017 followed the highly anticipated data from clinical studies. There were monumental successes, like the first-ever approval of a genetically modified living cell therapy, the first FDA application for a gene therapy or a medicine using RNA interference. There were also stinging failures, such as the latest in a long … Continue reading “15 For ’18: Key Clinical Data to Watch For Next Year (Part 1)”
Milestones of Innovation 15: Entering the New Atomic World
A momentous step into the atomic age happened around 3:20 p.m. Central War Time on Dec. 2, 1942, seventy-five years ago, in a vast, unheated space (a former squash doubles court) under the abandoned University of Chicago football stands at Stagg Field. A cadmium control rod was pulled out from a huge, painstakingly assembled cube … Continue reading “Milestones of Innovation 15: Entering the New Atomic World”
Bio Roundup: Migraine Data, Cancer Drug Combos, Azar Hearing & More
A pair of migraine drugs made a splash in biotech news this week with published data suggesting that they can reduce the frequency of headaches. These drugs still await an FDA decision, and their impact on patients over the long term are being watched closely. As many as 38 million Americans suffer from migraines, according … Continue reading “Bio Roundup: Migraine Data, Cancer Drug Combos, Azar Hearing & More”
Alexa Roundup: Amazon Improves Its Wish Fulfillment Device
From its earliest days, Amazon has built its business on removing the barriers between people and the things they want to buy. New voice computing technologies and business models unveiled at the company’s annual developer conference in Las Vegas this week represent the continuation of that vision. Alexa and the ecosystem of services and skills … Continue reading “Alexa Roundup: Amazon Improves Its Wish Fulfillment Device”
“Responsive” Machine Learning Could Lessen Cybersecurity Tradeoffs
In the wake of the Equifax breach and the global WannaCry ransomware outbreak earlier this year, tensions around cybersecurity are running high. According to a recent study conducted by the Ponemon Institute and sponsored by Barkly, seven out of 10 organizations are reporting their security risk has significantly increased during the past 12 months. Only … Continue reading ““Responsive” Machine Learning Could Lessen Cybersecurity Tradeoffs”
Drug Prices, Industry Ties Take Spotlight at HHS Nominee Azar Hearing
If Wednesday’s hearing for Health and Human Services Secretary Nominee Alex Azar is any indication, reining in drug prices and insurance premiums are the policy priorities that will guide Congress’s interaction with the department under a new leader. For the better part of the three-hour hearing by the Senate’s Health, Education, Labor and Pensions committee, … Continue reading “Drug Prices, Industry Ties Take Spotlight at HHS Nominee Azar Hearing”
With Good Data From Rival Migraine Drugs, Doctors Foresee Price Headaches
Amgen (NASDAQ: [[ticker:AMGN]]) and Teva Pharmaceutical (NYSE: [[ticker:TEVA]]) this afternoon are providing the most detailed look yet at two drugs in an emerging class of medicines meant to prevent migraine headaches, rather than just quell their symptoms. While the data for the two drugs, called erenumab (Aimovig, from Amgen and partner Novartis) and fremanezumab (from … Continue reading “With Good Data From Rival Migraine Drugs, Doctors Foresee Price Headaches”
Microsoft Stays Home, Plans Remodel to Urbanize Headquarters Campus
The Seattle area’s twin technology behemoths—Microsoft and Amazon—have pursued markedly different real estate strategies over the years, driven in part by the changing character of the region as they’ve grown. That divergence was underscored Tuesday by Microsoft’s announcement of a major redevelopment and expansion of its headquarters campus in Redmond, about 16 miles east of … Continue reading “Microsoft Stays Home, Plans Remodel to Urbanize Headquarters Campus”
Healthcare + A.I. Northwest: The Photos
Xconomy convened an outstanding group of innovators in healthcare and artificial intelligence for a half-day conference in Seattle earlier this month. As testament to the excitement around this topic, our event was sold-out with a lengthy waiting list. Those who made it in the door of Cambia Grove, our event host, were rewarded with a wide-angle … Continue reading “Healthcare + A.I. Northwest: The Photos”
Joining Trend, WI Creates New Business Entity: Benefit Corporations
On Monday, Wisconsin enacted legislation allowing companies to incorporate as benefit corporations. Although this may sound like routine, small-time legislative business, it is just as significant as major policy initiatives being debated in the halls of Congress. On issues from net neutrality to workers’ rights, corporations are perceived to—and often do—engage in practices that maximize … Continue reading “Joining Trend, WI Creates New Business Entity: Benefit Corporations”
Selocial Allows Fans and Bands to Discover, Publicize Indie Music
David “Stock” Baird is a songwriter, producer, and entrepreneur who spends a lot of time thinking of new and better ways for independent musicians to get paid for their work. He found a way to connect his passions by creating Selocial, a social network and music discovery tool that went live earlier this month. It … Continue reading “Selocial Allows Fans and Bands to Discover, Publicize Indie Music”
After Successful Pilot, Apprenti Expands Tech Training Program
Those of us who keep tabs on the tech world hear a lot about the challenges of hiring and retaining IT talent. According to a forecast by the U.S. Bureau of Labor Statistics, more than 1.3 million new computer programming and computer support specialist jobs will be created across the country by 2022, and as businesses … Continue reading “After Successful Pilot, Apprenti Expands Tech Training Program”
Locus Robotics Gets $25M to Help Warehouse Owners Compete With Amazon
As we head into holiday shopping season, here’s some news on the e-commerce warehouse front. Locus Robotics, based in Wilmington, MA, says it has secured $25 million in Series B funding led by Scale Venture Partners. The new money brings Locus Robotics’ total venture haul to at least $33 million. Founded in 2015, Locus Robotics makes … Continue reading “Locus Robotics Gets $25M to Help Warehouse Owners Compete With Amazon”
Ed Kaye on Sarepta’s Duchenne Quest, Rising to CEO & His New Startup
[Updated, 2:45 pm ET, see below] Ed Kaye never thought he’d run a biotech —until waking up one day in 2015 realizing not only that he could, but that Sarepta Therapeutics, where he was chief medical officer at the time, may fall apart if he didn’t. In March 2015, Kaye (pictured) was one of many … Continue reading “Ed Kaye on Sarepta’s Duchenne Quest, Rising to CEO & His New Startup”
Stratim CEO Sees Future with Costly Driverless Cars, but Low Ride Fares
Like many tech entrepreneurs, Sean Behr had a young business that was popular with consumers, but was also losing money. So in February of 2016, he decided to refocus his San Francisco startup on the small, but unexpectedly profitable aspect of his service that could operate in the black. That pivot put Behr in a … Continue reading “Stratim CEO Sees Future with Costly Driverless Cars, but Low Ride Fares”
Five Questions For … Barbary Brunner, Austin Technology Council CEO
Austin—Barbary Brunner says Austin has always felt like home. She has made career stops in Seattle, Los Angeles, and Denver, but says the Texas capital was a lodestar. “Every time I’d come visit, it felt like Austin was calling out to me,” Brunner says. “When I lived in Seattle, it’s the place I’d come to … Continue reading “Five Questions For … Barbary Brunner, Austin Technology Council CEO”
Bio Roundup: ICER Eyes Cost, Azar at HHS, Gates’s ALZ Cash & More
In our roundup this week, Alzheimer’s disease is in the news, thanks to billionaire Bill Gates and his personal pledge of $100 million toward R&D. That could equal the amount one startup hopes to raise in an IPO to develop drugs for Alzheimer’s and other brain diseases. If a treatment became available, could our health … Continue reading “Bio Roundup: ICER Eyes Cost, Azar at HHS, Gates’s ALZ Cash & More”
At Seattle Children’s, Another Piece of Ambitious CAR-T Plan in Place
The researchers and doctors at Seattle Children’s are embarking upon a complicated quest, involving multiple clinical studies of cutting-edge CAR-T cell therapies, to help kids and young adults with an aggressive form of leukemia. As of today, one key part of their plan can begin, thanks to a green light from the FDA. New clinical … Continue reading “At Seattle Children’s, Another Piece of Ambitious CAR-T Plan in Place”
Poshmark Picks Up $87.5M to Power the Social, Digital Wardrobe
Poshmark, a social media e-retail company, has raised $87.5 million in a Series D investment round led by Singapore sovereign wealth fund Temasek. That brings the total funding raised by the Redwood City, CA-based company to $160 million. Other investors in the firm include Mayfield, Menlo Ventures, GGV Capital, Inventus Capital, SoftTech VC, Union Grove … Continue reading “Poshmark Picks Up $87.5M to Power the Social, Digital Wardrobe”
Campaign Against Killer Robots Depicts Bleak Future as Nations Meet
This video is the stuff of nightmares. It depicts A.I.-directed drones loaded with small amounts of explosive, seeking out and killing targets autonomously. A slick tech executive makes his (for now) fictional pitch of this “improvement” on the large, Predator-style military drones that are familiar today. He shows a bomber flying over a city, dropping … Continue reading “Campaign Against Killer Robots Depicts Bleak Future as Nations Meet”
DFJ Co-Founder Jurvetson Exits Firm Amid Harassment Charges
[Updated 11/15/17, 11:10 am. See below.] One of Silicon Valley’s most prominent venture capital firm founders has joined the list of VCs who departed from their positions this year in the wake of sexual harassment allegations. Steve Jurvetson, co-founder of Draper Fisher Jurvetson (DFJ), confirmed via a Twitter post Monday that he has left the … Continue reading “DFJ Co-Founder Jurvetson Exits Firm Amid Harassment Charges”
IPO to Fuel Denali’s Drugs for Alzheimer’s, Other Brain Diseases
One of biotech’s richest private companies, Denali Therapeutics, has set its sights on an IPO to push ahead with treatments for Alzheimer’s and other confounding brain diseases. The filing marks $100 million as its IPO target, but market conditions often shift a company’s sights in the run-up to a debut. Denali’s disclosure comes on the … Continue reading “IPO to Fuel Denali’s Drugs for Alzheimer’s, Other Brain Diseases”
Milestones of Innovation 14: The Biggest Damn Firecracker I Ever Saw
At exactly 7 a.m. on Nov. 9, 1967, the roof of the press viewing stand at Cape Canaveral began shaking from what was happening more than three miles from us. The sky seemed to be cracking as a gleaming 363-foot tall rocket began pushing up from Launch Pad 39 and eastward over the Atlantic. As … Continue reading “Milestones of Innovation 14: The Biggest Damn Firecracker I Ever Saw”
Juno Dissects ROCKET Deaths, Will Aim Better CAR-T at Leukemia
When five patients with a difficult type of leukemia died last year in a clinical trial run by Juno Therapeutics, it was a big setback for the Seattle biotech and its plans for cutting-edge CAR-T cancer therapy. A year later, Juno is finally explaining what happened and promising to return with a new product. The … Continue reading “Juno Dissects ROCKET Deaths, Will Aim Better CAR-T at Leukemia”
Bio Roundup: Barron Joins GSK, Sage Bounces Back, Valeant Dumps Addyi
Call it a week of second chances. Multiple biotechs breathed new life into drugs sorely in need of it. Sage Therapeutics proved a drug that had failed a trial a rare form of epilepsy could be the first ever approved therapy for postpartum depression. Otonomy, reviving a hearing loss drug thought to be on the … Continue reading “Bio Roundup: Barron Joins GSK, Sage Bounces Back, Valeant Dumps Addyi”
What Sean Parker Shares with Einstein and the Labradoodle’s Inventor
Sean Parker, Facebook’s first president, just joined a group that’s a favorite topic of history listicles: He’s an innovator who has become abashed by the breakthrough he helped to create. Parker, in an interview with Axios on Wednesday, said Facebook’s founders consciously exploited “a vulnerability in human psychology,” by luring users into an addictive engagement … Continue reading “What Sean Parker Shares with Einstein and the Labradoodle’s Inventor”
Microsoft Ups Its Wisconsin Investments, Backs New Gener8tor Program
Microsoft is deepening its efforts to help Wisconsin foster more high-growth startups. The Seattle-based tech giant’s latest move in the Badger State is a new partnership with Gener8tor, an organization based in the state that runs training programs for early-stage companies, and invests in them. Gener8tor said Wednesday that its collaboration with Microsoft is aimed … Continue reading “Microsoft Ups Its Wisconsin Investments, Backs New Gener8tor Program”
Microsoft’s Strategy for Finding What’s Next in Healthcare A.I.
[Updated 11/10/17, 10:25 a.m. See below.] Microsoft is applying the same model it used to launch its quantum computing and chatbot efforts to innovation in healthcare, signaling the company’s ambition and optimism about the transformative potential of artificial intelligence technologies in this enormous endeavor. Peter Lee is the Microsoft Research executive in charge of the … Continue reading “Microsoft’s Strategy for Finding What’s Next in Healthcare A.I.”
Is Your Company Independent or Co-Dependent?
Steve Jobs was once famously quoted stating, “the secret of my success is that we have gone to exceptional lengths to hire the best people in the world.” Employees are a critical part of any company’s backbone, no matter the size or industry of the business. They are the driving force that executes the company … Continue reading “Is Your Company Independent or Co-Dependent?”
Biotech Roundup: Opioid News, ASH Preview, Boston Bio IPOs & More
The rising death toll from opioids has prompted policymakers to try various ways to take on the problem. President Trump’s opioid commission released its final report this week, calling for expansion of drug courts, better physician training, and penalties for insurers that don’t cover treatment. But the commission did not say how much its recommendations … Continue reading “Biotech Roundup: Opioid News, ASH Preview, Boston Bio IPOs & More”
Congress Urges Tech Firms to Control Content—But With Qualms
At Congressional hearings this week on Russia’s use of social media to interfere with the 2016 U.S. election, lawmakers pressed Facebook, Twitter, and Google to take exhaustive measures to stop the same thing from happening again. Lawmakers urged the companies to scour their networks to root out foreign advertisers, trolls, and bots; to eliminate messages … Continue reading “Congress Urges Tech Firms to Control Content—But With Qualms”
Etzioni on A.I. Hype, Reality, Lifesaving Potential, and More
Oren Etzioni, CEO of the Allen Institute for Artificial Intelligence (AI2), still isn’t worried about nefarious A.I. taking over the world, but says there are real and growing concerns about its potential impacts on society and the economy. That said, he is an A.I. optimist and sees potentially lifesaving applications emerging in autonomous vehicles and … Continue reading “Etzioni on A.I. Hype, Reality, Lifesaving Potential, and More”
PathAI Grabs $11M to Build A.I. Tools for Pathology
Investors continue to pour millions of dollars into startups attempting to apply artificial intelligence technologies to various problems in healthcare. The latest beneficiary is PathAI, a Cambridge, MA-based company developing A.I. software aimed at helping pathologists be more efficient and accurate in diagnosing disease. PathAI co-founder and CEO Andy Beck tells Xconomy that his company … Continue reading “PathAI Grabs $11M to Build A.I. Tools for Pathology”
Few Opioid Alternatives In Sight as Crisis Gains Political Attention
As opioid-related deaths skyrocket across the U.S., momentum to combat the epidemic has been mounting in Washington. But the crisis has also highlighted a glaring problem that no amount of politics or policymaking will solve soon: The lack of non-addictive pain medicines. “What is disappointing over the last half-century is that we haven’t really created … Continue reading “Few Opioid Alternatives In Sight as Crisis Gains Political Attention”
ASH Sneak Peeks: Novartis, Juno Update CAR-T Lymphoma Competition
[Corrected, 11/1/17, 5:20 p.m. ET. See below.] The annual American Society of Hematology meeting is next month. But previews of the big data presentations are out today, yielding more insight into what promises to be the first major competition in CAR-T cell therapy: Treatments for people with non-Hodgkin lymphoma (NHL) who have run out of … Continue reading “ASH Sneak Peeks: Novartis, Juno Update CAR-T Lymphoma Competition”
As Facebook Fights Fake News, LeCun Sees Bigger Role for A.I.
As top lawyers from Facebook, Google, and Twitter testify on Capitol Hill this week about Russians using their platforms to interfere in the 2016 U.S. presidential election, it’s becoming clearer that the fight against the spread of fake news won’t be won by humans alone. That’s according to Yann LeCun, a machine learning expert and … Continue reading “As Facebook Fights Fake News, LeCun Sees Bigger Role for A.I.”
Techstars Sustainability Adds to Growth of Sponsored Accelerators
After Techstars opened its first program in Boulder, CO, in 2007, the startup accelerator program expanded into three cities over the next four years. But then the real growth started happening. In 2011, Techstars began launching accelerators that focused on startups innovating in a specific sector in partnership with big companies. It partnered with Nike … Continue reading “Techstars Sustainability Adds to Growth of Sponsored Accelerators”
Markforged Turns Profit, Grabs $30M From Siemens, Microsoft, Porsche
Now that the hype over 3D printing has died down, some of the industry’s surviving startups have figured out how to build healthy businesses. Four-year-old Markforged says it’s one of them. The Watertown, MA-based company—known for 3D printers that produce plastic parts strengthened by carbon fiber and other materials—says its revenues have increased significantly this … Continue reading “Markforged Turns Profit, Grabs $30M From Siemens, Microsoft, Porsche”
Remitly Loads Up for Global Growth with $115M from PayU, Others
International money transfer business Remitly will add $115 million to its coffers through what would be the largest investment in a Seattle company in the last year. The investment—which requires Hart-Scott-Rodino approval due to its size, as well as sign-off from state regulators because Remitly is a licensed financial services provider—is expected to close by … Continue reading “Remitly Loads Up for Global Growth with $115M from PayU, Others”