So You Want to Start a Cybersecurity Company?

Cybercrime has become a global epidemic. Attacks will cost the world $6 trillion by 2021, research firm Cybersecurity Ventures says-–the greatest transfer of economic wealth in history and more profitable than the trade in all major illegal drugs. As the threat keeps rising, the cybersecurity industry keeps growing. According to data released in January by … Continue reading “So You Want to Start a Cybersecurity Company?”

Xealth Gets $11M, Aims to Be Surescripts of Digital Health Services

Doctors prescribe all sorts of things for their patients, like drugs, medical procedures, and changes to diet and exercise regimen. Prescribing a software application—one that helps a patient manage diabetes, for example—may sound futuristic to some people. But to Mike McSherry, CEO of Xealth, a Seattle-based startup that announced $11 million in new funding Wednesday to … Continue reading “Xealth Gets $11M, Aims to Be Surescripts of Digital Health Services”

FTC Queries Internet Providers on Consumer Data Collection and Use

The Federal Trade Commission, which has been digging into the privacy practices of tech giants Facebook and Google, is now training its sights on the internet service providers that bring us all our online content. In its role as a consumer protection agency, the FTC ordered Verizon, AT&T, T-Mobile, Comcast, Google Fiber, and other ISPs … Continue reading “FTC Queries Internet Providers on Consumer Data Collection and Use”

WI Watchlist: Dark Knight Fund, Morgridge “Flamingo” Grant & More

In the latest installment of the Wisconsin Watchlist, we’re tracking the fundraising plans of two new Milwaukee-area venture funds, and a pair of grants awarded to research and education projects in Madison. Read on for details. —State Representative Jason Fields, a Democrat from Milwaukee, aims to raise $10 million for a new venture capital fund … Continue reading “WI Watchlist: Dark Knight Fund, Morgridge “Flamingo” Grant & More”

Sanford Burnham Prebys, WARF Partner on Drug Discovery

A program launched last year by the Wisconsin Alumni Research Foundation to invest in promising biotech discoveries made on the University of Wisconsin-Madison campus will also work with the La Jolla, CA-based Sanford Burnham Prebys Medical Discovery Institute, the organizations said recently. The partnership is part of a broader movement to accelerate the “bench to … Continue reading “Sanford Burnham Prebys, WARF Partner on Drug Discovery”

Bio Roundup: Sage Postpartum Help, Biogen Bids Adu, Heart Beats & More

One group of people in dire need of medical relief got good news this week. The first drug for postpartum depression was approved. With its complicated logistics, side effects, and potential high cost, it won’t be for everyone who experiences the condition—1 of every 9 U.S. women giving birth. But at least it’s an option. … Continue reading “Bio Roundup: Sage Postpartum Help, Biogen Bids Adu, Heart Beats & More”

As Exact Sciences’ Sales Surge, CEO Reflects on 10-Year Turnaround

A decade ago, Kevin Conroy took the CEO job at Exact Sciences, a cancer diagnostic firm on the brink of death. Five years later, the FDA greenlit the company’s first product, Cologuard, which marked the first non-invasive, stool-based DNA screening test approved for detecting colorectal cancer. In the five years since then, Exact (NASDAQ: [[ticker:EXAS]]) … Continue reading “As Exact Sciences’ Sales Surge, CEO Reflects on 10-Year Turnaround”

New Accelerator Aims For Social Change With AR, VR, Gaming Startups

Games for Change, a non-profit that promotes the use of games and immersive technology for social good, is taking applications from startup teams for a new accelerator program it’s launching in New York City. New York-based Games for Change already encourages game and XR developers, by a variety of means, to build societal benefits into … Continue reading “New Accelerator Aims For Social Change With AR, VR, Gaming Startups”

U.S. Energy Dept. Awards $500M Supercomputer Contract to Intel, Cray

Computer chipmaker Intel and its subcontractor, Seattle-based Cray, say they expect a supercomputer they plan to eventually deliver will be a flop—an exaflop, that is. The U.S. Department of Energy’s Argonne National Laboratory has hired Intel (NASDAQ: [[ticker:INTC]]) and Cray (NASDAQ: [[ticker:CRAY]]) to build what the companies said Monday would be the first exascale supercomputer … Continue reading “U.S. Energy Dept. Awards $500M Supercomputer Contract to Intel, Cray”

The Role of the Student Engineer in Medicine and Innovation

The last 50 years have seen many great technical advances in medical treatments, ranging from drug delivery and imaging to skin grafts and prosthetics. These advances—both large and small—have drawn on many fields and have transformed patient care. When examining the current state of clinical technology, the focus is naturally on the technology and its … Continue reading “The Role of the Student Engineer in Medicine and Innovation”

Bio Roundup: Golumbeski’s Legacy, CRISPR Moratorium, Rebate Week & More

While all eyes in the biopharmaceutical world are currently trained on Bristol-Myers Squibb’s proposal to buy Celgene for $74 billion, it wasn’t that long ago that another company’s gaze was fixed on the Summit, NJ, drug maker. In the early 2000s, before the FDA approved Celgene’s flagship multiple myeloma drug lenalidomide (Revlimid), Novartis (NYSE: [[ticker:NVS]] … Continue reading “Bio Roundup: Golumbeski’s Legacy, CRISPR Moratorium, Rebate Week & More”

WI Watchlist: Foxconn Fund, UW Accelerator, MSOE A.I. Hall & More

It’s time to catch up on Wisconsin innovation news: —Jason Franklin will manage the Wisconn Valley Venture Fund, a $100 million fund formed last August by Foxconn Technology Group and three leading Wisconsin businesses and organizations: Advocate Aurora Health, Northwestern Mutual, and Johnson Controls (NYSE: [[ticker:JCI]]). Foxconn, a Taiwanese manufacturing giant, has said it’s building … Continue reading “WI Watchlist: Foxconn Fund, UW Accelerator, MSOE A.I. Hall & More”

Harley-Davidson Goes Electric: Behind the Scenes of LiveWire’s R&D

For more than a century, the throaty “potato, potato, potato” rumble of a Harley-Davidson motorcycle has been synonymous with the open road, freedom—rebellion, even—and, some might say, American masculinity. For non-gearheads, that iconic sound, introduced in 1909, is the result of Harley-Davidson’s (NYSE: [[ticker:HOG]]) traditional engine configuration, a V-twin with a 45-degree angle between the … Continue reading “Harley-Davidson Goes Electric: Behind the Scenes of LiveWire’s R&D”

Drug-Price Watchdog ICER Dives into Trump-Fueled Pharma Rebate Debate

[Updated 3/13/19, 12:20pm. See below.] With public and political winds blowing in the same direction, significant reform of the complicated U.S. drug-pricing system seems ever more likely. One part of the system that the Trump administration wants to overhaul are the secret rebates that drug makers, insurers, and middlemen negotiate behind closed doors. Replacements for … Continue reading “Drug-Price Watchdog ICER Dives into Trump-Fueled Pharma Rebate Debate”

The Life, Troubles, and Celgene Legacy of Deal Guru George Golumbeski

George Golumbeski is one of the most prolific dealmakers in the biopharmaceutical world. But the deal that changed his life is a pact he made with himself when he was ten years old. Playing with friends in front of his house in Hampton, VA, he watched his mother drag his dead-drunk father, a U.S. Air … Continue reading “The Life, Troubles, and Celgene Legacy of Deal Guru George Golumbeski”

Bio Roundup: Gottlieb Exits, Bristol Defends, Biogen Buys & More

In early 2017, Scott Gottlieb was considered the most moderate of the potential candidates to head the Food and Drug Administration, which is the most powerful regulator of medical products in the world. It wasn’t a high bar to clear. Libertarians who had questioned some of the basic premises of the FDA were in the … Continue reading “Bio Roundup: Gottlieb Exits, Bristol Defends, Biogen Buys & More”

Bright Cellars Uncorks $8.5M Round for Wine Subscription Service

A few years ago, the frothiest market in tech was arguably startups selling subscriptions to boxes of curated goods, such as clothing, beauty products, and food, which would arrive on customers’ doorsteps each month. The buzz around this area of e-commerce may have subsided a bit, but there are still a ton of box subscription … Continue reading “Bright Cellars Uncorks $8.5M Round for Wine Subscription Service”

Steering Lyft’s IPO: What Investors Will Weigh During the Roadshow

Much has been said about Lyft’s early lead over Uber in the “horserace” to become the first ride-hailing app company to go public. But now that San Francisco-based Lyft has filed its 276-page IPO prospectus with the U.S. Securities and Exchange Commission, potential investors can focus on much more detailed considerations as they decide whether … Continue reading “Steering Lyft’s IPO: What Investors Will Weigh During the Roadshow”

Blue Squad Aims to Bring Election Tech Up and Down the Ballot

Austin—All politics is local, the adage goes, and those campaigns are sorely stuck in analog mode. That’s why Shion Deysarkar co-founded Blue Squad two years ago as a “digital coalition” to support progressive candidates by providing them with greater access to accurate voter data. Now, Blue Squad is more formally launching as a political tech startup … Continue reading “Blue Squad Aims to Bring Election Tech Up and Down the Ballot”

Two Years and Done: FDA Commissioner Gottlieb To Resign

Two months after insisting on Twitter that he wasn’t going anywhere, Food and Drug Administration Commissioner Scott Gottlieb announced his resignation today. He leaves a record of health and medical regulation that was more active than critics who spoke out against his nomination in early 2017 might have expected. Gottlieb’s remit extended beyond drugs, of … Continue reading “Two Years and Done: FDA Commissioner Gottlieb To Resign”

Tasso Gets $6M For Device That Lets Users Self-Collect Blood Samples

Tasso, a Seattle-based startup that is developing an at-home blood sample collection device, announced Tuesday it has raised $6.1 million from investors. The new money will support its effort to launch sales of the device, Tasso OnDemand, in the coming months, and to add staff, Tasso says. Vertical Venture Partners, a Silicon Valley-based investment fund, … Continue reading “Tasso Gets $6M For Device That Lets Users Self-Collect Blood Samples”

WI Watchlist: Kauffman Ranking, Driverless Shuttles, Space Research

Here are some of the latest headlines from Wisconsin’s innovation community: —Well, it’s not last place, but it’s still not a great showing for Wisconsin in the latest assessment of entrepreneurial activity in each state by the Ewing Marion Kauffman Foundation. Wisconsin ranked 45th in the foundation’s “early-stage entrepreneurship index” released in February, which examined … Continue reading “WI Watchlist: Kauffman Ranking, Driverless Shuttles, Space Research”

Retailers Turn to Analytics, 3D Tech to Promote Fit, Reduce Returns

One size fits most (at best), and a women’s sizing system created during the Depression doesn’t gibe in an e-commerce business that prizes personalization. That’s why startups are turning to new technologies like 3D scanning and machine learning software to produce customized clothing that can be made for the masses. “People want to buy a … Continue reading “Retailers Turn to Analytics, 3D Tech to Promote Fit, Reduce Returns”

Privacy Watch: FTC, Facebook, EU, the Cloud Act, & More CA bills

Privacy issues continued to boil to the surface in February. In part, it’s a reflection of the long tail of consequences that began in early 2018 when the broader public learned that Facebook had shared data from millions of user profiles with now-shuttered political marketing firm Cambridge Analytica. The consequences of that wider public awareness … Continue reading “Privacy Watch: FTC, Facebook, EU, the Cloud Act, & More CA bills”

SPECIAL REPORT: 2019 Biopharma Outlook – Facing an Uncertain Future

After years of boom times, the U.S. biopharmaceutical industry is dealing with unprecedented threats on several fronts: public backlash against high drug prices, slowing sales, and the possibility of more government regulation. In this Xconomy Special Report, our veteran biotech journalists Alex Lash and Ben Fidler bring you deep insights, based on conversations with key … Continue reading “SPECIAL REPORT: 2019 Biopharma Outlook – Facing an Uncertain Future”

Bio Roundup: Pharma in DC, Bristol-Cel in Trouble, Roche Gets A Spark

Could a shareholder revolt doom the planned marriage of Bristol-Myers Squibb and Celgene? Analysts have hinted at the possibility since the two companies shook hands in January, but the threat became real this week. Bristol (NYSE: [[ticker:BMY]]) and Celgene (NASDAQ: [[ticker:CELG]]) have campaignned heavily, starting with a joint presentation by their CEOs at the J.P. … Continue reading “Bio Roundup: Pharma in DC, Bristol-Cel in Trouble, Roche Gets A Spark”

Ex-Google CEO: New MIT College Could Help Shrink A.I. Talent Gap

Eric Schmidt believes we’re entering an era where artificial intelligence will underpin most facets of human life. But we don’t yet have enough people with the right skills to build that future. Schmidt, the former CEO of Google and former executive chairman of its parent company Alphabet (NASDAQ: [[ticker:GOOGL]]), argues that the A.I. talent shortage … Continue reading “Ex-Google CEO: New MIT College Could Help Shrink A.I. Talent Gap”

7 Tips for Biotech Companies Seeking Capital in a Volatile Market

Last year was a remarkable year for biotech companies going public. Not only did an unusually large number of biotech companies go public, but a significant number of early-stage biotech companies went public at premium valuations relative to their later-clinical stage peers. There were approximately 58 biotech IPOs in 2018 (excluding offerings with under $25 … Continue reading “7 Tips for Biotech Companies Seeking Capital in a Volatile Market”

Walmart’s Store No 8 Acquires Aspectiva to Bring A.I. to Shopping

Walmart’s Store No 8 innovation arm has acquired an Israeli machine learning startup, the retail giant announced Wednesday. Aspectiva joined the two-year-old Store No 8 Monday, and its employees will remain in Tel Aviv. “Store No 8’s record of innovation and of developing capabilities that will transform retail as we know it makes for the … Continue reading “Walmart’s Store No 8 Acquires Aspectiva to Bring A.I. to Shopping”

Pharma CEOs to Senate: We Will Lower Drug Prices if Rebates Go Away

Seven top pharmaceutical executives gathered today in Washington, DC, for a Senate hearing on drug prices, bringing face-to-face two groups held in the lowest esteem possible by the American public. Top executives from seven companies—AbbVie, AstraZeneca, Bristol-Myers Squibb, Merck, Johnson & Johnson, Pfizer, and Sanofi, which represent a combined $1.1 trillion in market value—stuck to … Continue reading “Pharma CEOs to Senate: We Will Lower Drug Prices if Rebates Go Away”

Exact Sciences Eyes Cologuard Market Expansion After “Landmark Year”

[Updated 2/22/19, 2:42 pm CT. See below.] Exact Sciences screened 934,000 patients for colorectal cancer in 2018 using its stool-based diagnostic test, Cologuard, resulting in a 71 percent surge in annual revenue to $454.5 million, the company announced Thursday. Exact (NASDAQ: [[ticker:EXAS]]), which relocated from the Boston area to Madison, WI, in 2009, is one … Continue reading “Exact Sciences Eyes Cologuard Market Expansion After “Landmark Year””

WI Watchlist: Rockwell, Wellbe, Generac, API Healthcare & More

Here’s a roundup of recent news from Wisconsin’s high-tech industries: —Rockwell Automation (NYSE: [[ticker:ROK]]), the Milwaukee-based seller of hardware and software that enables industrial automation, is forming a joint venture with Houston-based Schlumberger (NYSE: [[ticker:SLB]]), a maker of products for drilling and other tasks in the oil and gas industry. The new venture, called Sensia, … Continue reading “WI Watchlist: Rockwell, Wellbe, Generac, API Healthcare & More”

Bio Roundup: NASH News, Merck Strikes, Digital Tokens & More

The growing epidemic of the fatty liver disease known as NASH, which has no FDA-approved treatment, has led to a frenzied race among drug companies. This week, one company, Intercept Pharmaceuticals, solidified its lead. But how much will being first to the finish line mean when all is said and done? Intercept (NASDAQ: [[ticker:ICPT]]) reported … Continue reading “Bio Roundup: NASH News, Merck Strikes, Digital Tokens & More”

Google Confirms New Madison Office, Part of $13B National Expansion

Google confirmed this week that it will expand its satellite office in Madison, WI, as part of a $13 billion investment in data centers and offices nationwide in 2019. Xconomy reported Jan. 31 that the Bay Area tech giant intends to triple the size of its downtown Madison outpost by adding a second office, located … Continue reading “Google Confirms New Madison Office, Part of $13B National Expansion”

Bio Roundup: Trump’s Scalps, Policy Pressure, NASH Crash & More

While politicians continue to debate what kind of healthcare system is best for the American people, the mostly U.S.-based pharmaceutical industry is trying to convince those same politicians—and anyone else who will listen—that what’s good for the industry is also good for America. Forcing drug prices lower, industry argues, would be bad for our health, … Continue reading “Bio Roundup: Trump’s Scalps, Policy Pressure, NASH Crash & More”

WI Watchlist: FluGen, Propeller Health, Gener8tor, EnSync

Here are some of the latest headlines from Wisconsin’s innovation community: —FluGen, a Madison-based company trying to develop a universal influenza vaccine, announced topline, preliminary data from a Phase 2 study that demonstrated its M2SR vaccine proved effective in countering a “mismatched” flu virus. The flu virus that makes its rounds each year doesn’t always … Continue reading “WI Watchlist: FluGen, Propeller Health, Gener8tor, EnSync”

Finding True Love Can Be Ruff, But This Startup Could Have Your Match

Too many people treat pet adoption like a one-night stand. “You look at a dog, and see his eyes, and think he’s cute,” says Tama Lundquist, co-president of Houston PetSet, an organization that works with about 70 animal shelters in the Houston area. “But if you’re a couch potato and he likes to run, that’s … Continue reading “Finding True Love Can Be Ruff, But This Startup Could Have Your Match”

Losing “Scalps”? Despite Pharma Fear, A Split on Trump Rx-Price Plans

Despite angry presidential tweets and other anti-pharma rhetoric, the drug industry has benefited under the Trump administration, thanks in part to a massive corporate tax cut. Indeed, for nearly two decades, the industry has been able to fend off its critics and gain win after win from politicians and regulators, including tax holidays, faster drug … Continue reading “Losing “Scalps”? Despite Pharma Fear, A Split on Trump Rx-Price Plans”

Bain Capital Backs ImageMoverMD’s Medical Image Management Tools

ImageMoverMD, a Madison, WI-based startup trying to modernize the processes for capturing and managing medical images, said Friday it pulled in a $4 million venture investment led by Bain Capital Ventures, Cultivation Capital, and previous backer HealthX Ventures. The startup said it plans to use the new cash to expand the capabilities of its software … Continue reading “Bain Capital Backs ImageMoverMD’s Medical Image Management Tools”

Bio Roundup: New CRISPR Feud, A NY Splash, Pharma vs. Congress & More

If you’re into congressional spectacles, stay tuned later this month. A group of top biopharma executives—the full roster isn’t known yet—will testify at a Feb. 26 hearing before the Senate Committee on Finance to defend their drug pricing practices. No executives showed up for the previous hearing, but reports indicate industry has changed its stance … Continue reading “Bio Roundup: New CRISPR Feud, A NY Splash, Pharma vs. Congress & More”

WI Watchlist: Epic Systems, M-WERC, Nordic, Dianomi Therapeutics

It’s time to catch up on some recent headlines from Wisconsin’s innovation community: —Dianomi Therapeutics, a Madison-based life sciences startup, said it received a $3 million investment from San Diego-based Ligand Pharmaceuticals (NASDAQ: [[ticker:LGND]]). The investment includes $2 million in equity funding and $1 million in convertible debt financing, according to a Dianomi spokesperson. As … Continue reading “WI Watchlist: Epic Systems, M-WERC, Nordic, Dianomi Therapeutics”

Fasetto Downloads $6M for Connected Devices and Cloud Tools

Fasetto, a startup developing tech gadgets and software in Superior, WI, has pulled in $6 million in equity funding, according to a document filed this week with the SEC. There was one investor in the deal, the filing shows. Six-year-old Fasetto previously raised at least $13 million from investors, per SEC filings. Xconomy has e-mailed … Continue reading “Fasetto Downloads $6M for Connected Devices and Cloud Tools”

Cancer Cures and the Importance of Communicating Responsibly

Last week, it was reported by multiple media outlets (see here, and here, and here) that a group of Israeli scientists had found “a cure for all cancer” and that it could be ready within a year. As a long-time life sciences industry executive my knee-jerk reaction was not “finally!” but “crap, not again!” As … Continue reading “Cancer Cures and the Importance of Communicating Responsibly”

Privacy Watch: Facebook Rebounds, But Privacy Concerns Accelerate

After Facebook posted a record profit of almost $7 billion in the fourth quarter on nearly $17 billion in revenue last week, an early investor, former advisor to CEO Mark Zuckerberg, and current shareholder said he’s making it a mission to “fix’’ the 15-year-old tech giant. Roger McNamee, in a podcast interview with The New … Continue reading “Privacy Watch: Facebook Rebounds, But Privacy Concerns Accelerate”

George Mosher, Milwaukee Startup Investor & Philanthropist, Has Died

George Mosher, a Milwaukee businessman and one of Wisconsin’s most prolific startup investors, died on Thursday after a fight with pancreatic cancer. He was 79. A Boston native, Mosher moved to Milwaukee in 1965 after graduating from Harvard University’s business school. He became president of Business and Institutional Furniture, a catalog furniture company that served … Continue reading “George Mosher, Milwaukee Startup Investor & Philanthropist, Has Died”

Bio Roundup: Alzheimer’s Fail, Drug Price Plan, Gene Therapies & More

Pharmaceutical companies typically raise prescription drug prices at the start of each year and this year was no different. The increases were the latest reminder that, despite President Trump’s fiery campaign rhetoric, the administration had done little to actually lower drug prices. But a new plan aimed at the secretive rebate deals between pharma companies … Continue reading “Bio Roundup: Alzheimer’s Fail, Drug Price Plan, Gene Therapies & More”

UAS Laboratories Grabs $21.7M for Probiotics Manufacturing Business

UAS Laboratories, a Wausau, WI-based probiotics maker, has pulled in $21.7 million in new equity financing, according to a document filed with securities regulators. Twelve investors participated in the deal, the document shows. The funding comes almost two years since UAS Labs last raised money, a $21.2 million equity financing round. UAS Labs formulates, blends, … Continue reading “UAS Laboratories Grabs $21.7M for Probiotics Manufacturing Business”

Google’s Madison Expansion to Triple Size of Local Offices

[Updated 1/31/19, 12:12 pm CT. See below.] Google is building out a new office near downtown Madison, WI, in an expansion project that will triple the size of its local outpost—giving it enough space for an estimated total of 200-plus local employees, Xconomy has learned. The Bay Area-based tech giant, part of parent company Alphabet … Continue reading “Google’s Madison Expansion to Triple Size of Local Offices”

Packers, Microsoft Play to Green Bay’s Strengths With TitletownTech

As Jill Enos tries to improve the environment for entrepreneurs in Green Bay, WI, she says she has studied how communities such as Boulder, CO, Kansas City, MO, and Wilmington, NC, have attempted to build startup hubs. The key? Don’t try to be something you’re not. That means, for example, focusing on sectors that have … Continue reading “Packers, Microsoft Play to Green Bay’s Strengths With TitletownTech”

Retailers Brace For Possible Economic Headwinds in 2019

Even as retailers struggle with a technology-disrupted business model and changing consumer desires, at least a generally positive overall economy and low unemployment rates seemed to keep shoppers’ wallets open. But a 2019 that started with stock market losses, a recently ended (but longest-ever) government shutdown, and other headwinds might now force consumers to pull … Continue reading “Retailers Brace For Possible Economic Headwinds in 2019”