GI Dynamics Gets European Approval

GI Dynamics has garnered European marketing approval for its temporary intestinal implant for treating Type 2 diabetes and obesity, according to the Lexington, MA-based firm. The company said it plans to begin selling the device, called the EndoBarrier, in Europe in the first half of 2010. The firm’s venture backers include Advanced Technology Ventures, Catalyst … Continue reading “GI Dynamics Gets European Approval”

Arena Turns In FDA Application

San Diego-based Arena Pharmaceuticals (NASDAQ: [[ticker:ARNA]]) said today it has filed its application to the FDA for clearance to start marketing lorcaserin for weight loss. The application includes information on 18 clinical trials that enrolled almost 8,600 patients, including the pivotal trials known as Bloom and Blossom. The company had forecasted previously it would complete … Continue reading “Arena Turns In FDA Application”

Zulily Gets Funded, Ontela Merges with Photobucket, OncoGenex Secures $60M from Teva, & More Seattle-Area Deals News

It was another pretty busy week for deals in the Northwest, as everyone scrambled to beat the holiday rush. Lots of action in biotech, Internet, and mobile. —Seattle-based ZymoGenetics (NASDAQ: [[ticker:ZGEN]]) is getting back the full rights to its drug for surgical bleeding in the U.S. and every other country except Canada, under a restructured … Continue reading “Zulily Gets Funded, Ontela Merges with Photobucket, OncoGenex Secures $60M from Teva, & More Seattle-Area Deals News”

Genocea Eyes Vaccines that Treat, Not Just Prevent, Infectious Diseases

Genocea Biosciences sees a big potential in high-speed technology for discovering vaccines—not only ones that prevent diseases, but also ones that treat them. Indeed, the Cambridge, MA-based biotech has decided to pursue an immune-boosting therapy for genital herpes as its lead product candidate. Genocea (pronounced Jen-O-shuh) has been one of the biotech startups to watch … Continue reading “Genocea Eyes Vaccines that Treat, Not Just Prevent, Infectious Diseases”

Blue Is the New Green: Why Energy Entrepreneurs Need to Think Different

Many innovators lament that the time-honored VC model does not work for what they call “cleantech” or “greentech.” They raise as proof the capital intensivity and long timeframes for energy start-ups. I say they have it backwards. Energy will get solved when the energy ecology changes to fit the VC model, not vice versa. Take … Continue reading “Blue Is the New Green: Why Energy Entrepreneurs Need to Think Different”

Scandal, Swine Flu, Shareholder Disputes, and More: 2009 Was Quite a Year for San Diego’s Life Sciences Industry

Covering the life sciences in San Diego is never dull, and the news flow last year provided plenty of drama. What follows are some highlights from the past year: — Embattled tools company Sequenom (NASDAQ: [[ticker:SQNM]]) scuttled the debut of a non-invasive prenatal Down syndrome test amid a data-mishandling scandal. CEO Harry Stylli was fired … Continue reading “Scandal, Swine Flu, Shareholder Disputes, and More: 2009 Was Quite a Year for San Diego’s Life Sciences Industry”

VLST Cuts Jobs To Preserve Cash, Still Feeding Novo Nordisk Pipeline

VLST, the Seattle-based biotech company seeking new ways of treating autoimmune diseases, has recently completed a round of layoffs. I received a tip that the company eliminated about 30 percent of its workforce in recent weeks. CEO Marty Simonetti confirmed that job cuts have occurred, but wouldn’t say how many people were let go or … Continue reading “VLST Cuts Jobs To Preserve Cash, Still Feeding Novo Nordisk Pipeline”

Metaplace Pulling Plug on Website

San Diego-based Metaplace co-founder Ralph Koster announced on his blog today that the venture-backed company is shutting down Metaplace.com, its user-generated content website, effective Jan. 1. Koster, the former chief creative officer at Sony Online, says the Metaplace website, which offers users an online marketplace and platform for building their own social networking rooms “just … Continue reading “Metaplace Pulling Plug on Website”

MIT Media Lab Director Aims to Transform Healthcare—By Bringing Patients Front and Center

An avalanche of new technology promises to transform healthcare. You’ve heard a lot about it: Electronic medical records. New ways to mine genomic data to match patients with the right medicines. Everything from iPhone apps and robots to help you exercise or take your meds. Not to mention relatively “old” advances like digital imaging and … Continue reading “MIT Media Lab Director Aims to Transform Healthcare—By Bringing Patients Front and Center”

My Top 10 List of Innovations Across the Spectrum

Here are my top 10 innovations that are coming to the forefront in 2010. Of course, none of these would be possible without the economic engine that is embodied by the USA Science & Engineering Festival, which is creating the innovative minds of the future. 1) High-tech treatment of nuclear waste, a technology that solves … Continue reading “My Top 10 List of Innovations Across the Spectrum”

Viewfinity Secures $8,600,000 Series B Financing

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=b90b6112-32f1-4153-b55a-81f49b1b14f6&Preview=1 Date 12/22/2009 Company Name Viewfinity Mailing Address 1050 Winter Street Waltham, MA 02451 Company Description Viewfinity offers uncomplicated systems management solutions to manage, support and control desktops, laptops and Windows servers, regardless of worker location, via SaaS-enabled software. In four easy steps, and in less than 10 minutes, IT departments can … Continue reading “Viewfinity Secures $8,600,000 Series B Financing”

LiveMocha Receives $8,000,000 Series B Financing Round

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=2480a31f-9635-4803-b6a5-43f7d487f011&Preview=1 Date 12/22/2009 Company Name LiveMocha Mailing Address 11000 33rd NE Bellevue, WA 98004 Company Description The company provides an online website to assist users in learning new languages. Website http://www.livemocha.com Transaction Type Venture Equity Transaction Amount $8,000,000 Transaction Round Series B Proceeds Purposes Proceeds purposes were not disclosed. M&A Terms Venture … Continue reading “LiveMocha Receives $8,000,000 Series B Financing Round”

Azuro Secures $1,000,000 New Financing Round

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=e04a1aa9-3fe0-4451-98a1-d9973c397aeb&Preview=1 Date 12/22/2009 Company Name Azuro Mailing Address 5201 Great America Parkway Santa Clara, CA 95054 Company Description Azuro is provider of electronic design automation (EDA) software for digital semiconductor chip design. Azuro’s unique technology enables electronics companies around the world to implement digital clock networks with significantly less manual effort and … Continue reading “Azuro Secures $1,000,000 New Financing Round”

Pinch Media Acquires Flurry for Undisclosed Sum

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=efe46b67-ad33-4124-83be-916affb8af25&Preview=1 Date 12/22/2009 Company Name Flurry Mailing Address 282 2nd Street San Francisco, CA 94105 Company Description flurry, inc., a Delaware corporation, is a leader in developing next-generation mobile applications. flurry is an easy-to-use mobile email and RSS solution that works on hundreds of different cell phone models and thousands of email … Continue reading “Pinch Media Acquires Flurry for Undisclosed Sum”

EyeGate Pharma, Delivering Drugs Into the Eye, Raises $11M Out of $23M Round

EyeGate Pharma, a Waltham, MA-based company developing more effective ways to deliver drugs into the eye, has raised $11 million in new financing out of an equity round that could potentially bring in $22.7 million, according to a regulatory filing today. EyeGate hasn’t issued a statement on the financing, and a company spokesman couldn’t immediately … Continue reading “EyeGate Pharma, Delivering Drugs Into the Eye, Raises $11M Out of $23M Round”

ZymoGenetics Regains Full U.S. Rights to Recothrom as Bayer Walks Away

If ZymoGenetics is going to make its lone marketed product into a success, it will have to do it on its own. The Seattle-based biotech company said today that its partner, Germany-based Bayer, is walking away from its U.S. commercial rights to the drug for surgical bleeding. ZymoGenetics (NASDAQ: [[ticker:ZGEN]]) said today it is getting … Continue reading “ZymoGenetics Regains Full U.S. Rights to Recothrom as Bayer Walks Away”

Qualcomm Plans to Repeat Global QPrize, With a Few Changes

After reporting reporting last month that Israeli startup Panoramic Power won the inaugural QPrize, the incentive prize organized by Qualcomm Ventures, I recently got a chance to discuss the outcome with Nagraj Kashyap, vice president of Qualcomm Ventures. He says the San Diego wireless industry giant intends to organize a second round of its business … Continue reading “Qualcomm Plans to Repeat Global QPrize, With a Few Changes”

Ex-Microsoft CFO Liddell Joins GM

Chris Liddell, Microsoft’s former chief financial officer, has been named CFO and vice chairman of General Motors, the Detroit-based automaker. Liddell will lead GM’s global financial and accounting operations starting in the new year, and will report directly to Ed Whitacre, GM’s chairman and CEO. GM says it employs 209,000 people around the world and … Continue reading “Ex-Microsoft CFO Liddell Joins GM”

The New Google: Internet Giant Opens Up About Real-Time and Local Search, Cloud Computing, and Data Liberation

When it comes to product and business strategy, Google is one of the most secretive companies around. So I was pleased when the Internet giant agreed to grant me a series of interviews last week, most of them with senior product managers from its Mountain View, CA, headquarters. I touched on elements of Google’s technology … Continue reading “The New Google: Internet Giant Opens Up About Real-Time and Local Search, Cloud Computing, and Data Liberation”

Isis Nabs $10M from OncoGenex Deal

Isis Pharmaceuticals (NASDAQ: [[ticker:ISIS]]), the Carlsbad, CA-based biotech company, said today it will receive a $10 million payment from OncoGenex Pharmaceuticals in connection with OncoGenex’s new partnership with Teva Pharmaceutical. Bothell, WA-based OncoGenex (NASDAQ: [[ticker:OGXI]]) secured a worldwide partnership with Teva to develop OGX-011, an antisense therapy for prostate cancer. Isis will receive $10 million … Continue reading “Isis Nabs $10M from OncoGenex Deal”

Seattle Genetics Bags $12M From GSK

Seattle Genetics, the Bothell, WA-based developer of antibody drugs for cancer, said today it has secured $12 million in upfront payments from GlaxoSmithKline in exchange for technology that links antibodies to toxins that make them more potent. Seattle Genetics stands to receive $390 million of milestones if all of the antibody-drug conjugates GlaxoSmithKline is developing … Continue reading “Seattle Genetics Bags $12M From GSK”

Javelin Pharma Agrees to Merger with Myriad Pharma

Cambridge, MA-based Javelin Pharmaceuticals (AMEX:[[ticker:JAV]]) has agreed to be acquired by Myriad Pharmaceuticals (NASDAQ:[[ticker:MYRX]]) of Salt Lake City in an all-stock merger, the companies reported last week. The merger agreement would initially give Javelin shareholders control of 41 percent of the stock in the combined company and up to 45 percent ownership of the merged … Continue reading “Javelin Pharma Agrees to Merger with Myriad Pharma”

OncoGenex Grabs $60M Upfront From Teva for Rights to Cancer Drug, Shares Drop Anyway

[Updated: 12:30 pm Eastern time 12/21/09, with stock reaction.] The Cinderella story of Seattle biotech in 2009 is making more news. Bothell, WA-based OncoGenex Pharmaceuticals (NASDAQ: [[ticker:OGXI]]) is announcing today it has clinched $60 million in upfront payments from Israel-based Teva Pharmaceutical for the right to co-develop an experimental prostate cancer drug that has been … Continue reading “OncoGenex Grabs $60M Upfront From Teva for Rights to Cancer Drug, Shares Drop Anyway”

Agios, Seeking to Starve Cancer Cells to Death, Wins Support from Brain Tumor Foundation

Cancer cells can essentially get addicted to food, and Agios Pharmaceuticals thinks it has a groundbreaking way to starve them to death. Now it’s getting some help to test the idea from a foundation started by the family of AOL founder Steve Case. The Cambridge, MA-based biotech company is announcing today that it has secured … Continue reading “Agios, Seeking to Starve Cancer Cells to Death, Wins Support from Brain Tumor Foundation”

Qualcomm’s Top Executives Talk Shop, Verari Lays Off Nearly Everyone, Assay Depot Goes From Biotech Startup to Online Merchant, & More San Diego BizTech News

San Diego’s tech news slowed to a trickle last week, as considerable speculation focused on the restructuring at Verari Systems, which included laying off most of the data equipment supplier’s workforce. Keep reading to get the latest news. —San Diego-based Verari Systems abruptly laid off most of its employees, prompting a flurry of reports that … Continue reading “Qualcomm’s Top Executives Talk Shop, Verari Lays Off Nearly Everyone, Assay Depot Goes From Biotech Startup to Online Merchant, & More San Diego BizTech News”

India’s Innovation Front Lines 2009 (Part 1): Of “Jugaar” and A Quick Recovery from Global Recession

Driving from Delhi to Jaipur on the Delhi-Jaipur highway, December 17, 2009—The new 10-lane Gurgaon highway, opened a year back, is already at capacity. The first 30 miles. through the industrial suburbs of Delhi, are stop-and-go traffic. The Maruti-Suzuki car factories and Hero-Honda motorcycle factories and their parasitic ecosystem for auto jug manufactures ring the … Continue reading “India’s Innovation Front Lines 2009 (Part 1): Of “Jugaar” and A Quick Recovery from Global Recession”

Microsoft’s Director of Environmental Sustainability Talks Green Initiatives, Copenhagen Summit

In the past, Microsoft has had a reputation for being slow moving in the areas of green technology and energy-saving innovation. However, in the last two years, the corporation seems to have turned the tide, stepping up to the sustainability plate and implementing a number of company-wide green initiatives. First, it hired Rob Bernard as … Continue reading “Microsoft’s Director of Environmental Sustainability Talks Green Initiatives, Copenhagen Summit”

Top Five Tech Advances of the 2000s

[Editor’s Note: As the decade comes to an end, we’ve asked Xconomists and other technology leaders around the country to identify the top innovations they’ve seen in their fields the past 10 years, or predict the top disruptive technologies that will impact the next decade.] 1—Digital camera proliferation. Digital cameras and camera phones have become … Continue reading “Top Five Tech Advances of the 2000s”

Myriad Pharmaceuticals Acquires Javelin Pharmaceuticals for Undisclosed Sum

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=44660082-8474-435e-a2e4-5e4b4f0c91fe&Preview=1 Date 12/21/2009 Company Name Javelin Pharmaceuticals Mailing Address 125 CambridgePark Drive Cambridge, MA 02140 Company Description Javelin is a specialty pharmaceutical company that applies innovative proprietary delivery technologies to develop new, improved formulations of existing drugs that target unmet and underserved medical needs in the growing pain management market. Website http://www.javelinpharmaceuticals.com … Continue reading “Myriad Pharmaceuticals Acquires Javelin Pharmaceuticals for Undisclosed Sum”

BridgeCo Receives $7,500,000 New Financing Round

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=8f188ab0-fe11-4d05-b645-4bd61115f7a2&Preview=1 Date 12/21/2009 Company Name BridgeCo Mailing Address 400 Continental Blvd 6th Floor El Segundo, CA 90245 Company Description BridgeCo, a networked entertainment pioneer, offers the world’s most comprehensive, cost-effective and highly integrated processor IC and software platforms for connecting Internet media sources, computers and consumer electronics throughout the home. Website http://www.bridgeco.com … Continue reading “BridgeCo Receives $7,500,000 New Financing Round”

EyeGate Pharmaceuticals Garners $11,000,000 New Funding Round

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=5c92652f-c5c4-44a6-8e23-eb0353b4ab92&Preview=1 Date 12/21/2009 Company Name EyeGate Pharmaceuticals Mailing Address 100 Beaver Street Waltham, MA 02453 Company Description EyeGate Pharma is focused on replacing ocular injections and other invasive methods of ocular disease treatment. Our goal is to build a pipeline of safer, more effective and patient friendly ocular treatments based on our … Continue reading “EyeGate Pharmaceuticals Garners $11,000,000 New Funding Round”

Avantis Medical Systems Receives $1,400,000 New Financing Round

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=02e52eb5-e260-4d31-a439-133f2f053f62&Preview=1 Date 12/21/2009 Company Name Avantis Medical Systems Mailing Address 263 Santa Ana Court Sunnyvale, CA 94085-4511 Company Description Avantis Medical Systems, Inc. is a California-based medical device company founded to develop and manufacture catheter-based endoscopic devices. Its initial focus is on devices for use in both detecting and treating cancers of … Continue reading “Avantis Medical Systems Receives $1,400,000 New Financing Round”

Zipline Medical Garners $1,000,000 New Funding Round

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=eb70ae66-5d17-4251-826e-2e8b9f3a0d41&Preview=1 Date 12/21/2009 Company Name Zipline Medical Mailing Address 1916 Fallen Leaf Ln Los Altos, CA 94024 Company Description Zipline Medical is a health care startup that has yet to reveal any products or services. Website Undisclosed Transaction Type Venture Equity Transaction Amount $1,000,000 Transaction Round Undisclosed Proceeds Purposes Proceeds purposes were … Continue reading “Zipline Medical Garners $1,000,000 New Funding Round”

Lookout Lands $5,500,000 New Funding Round

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=abd6fd4d-ffaf-4d5c-b6c4-4334103b0dbc&Preview=1 Date 12/21/2009 Company Name Lookout Mailing Address 539 Bryant St. San Francisco, CA 94107 Company Description Lookout is a mobile security company dedicated to making the mobile experience safe for everyone. Website Undisclosed Transaction Type Venture Equity Transaction Amount $5,500,000 Transaction Round Undisclosed Proceeds Purposes Proceeds purposes were not disclosed. M&A … Continue reading “Lookout Lands $5,500,000 New Funding Round”

Melodeo Spoofs Apple-IBM Ad, Welcomes Steve Jobs to the Cloud

Anyone else out there remember the famous 1981 ad by Apple in the Wall Street Journal, welcoming competitor IBM into the personal computer age? The ad was Apple’s stake in the ground, saying it had invented the first PC system—and predicting massive growth and competition in the burgeoning industry. The rest, as they say, is … Continue reading “Melodeo Spoofs Apple-IBM Ad, Welcomes Steve Jobs to the Cloud”

Cell Therapeutics Dangles New Bonuses to Execs for Pixantrone Approval, Boosting Stock

Cell Therapeutics has survived a near-death experience this year, and now it is dishing out a new batch of potentially rich rewards for management to stick around at least two more years. The Seattle-based biotech company (NASDAQ: [[ticker:CTIC]]) said today in a regulatory filing that the board’s compensation committee has approved a new series of … Continue reading “Cell Therapeutics Dangles New Bonuses to Execs for Pixantrone Approval, Boosting Stock”

Report: Security Breach Behind Twitter Outage Did Not Originate with New Hampshire DNS Provider

A hacker attack on the domain name system (DNS) servers that enable access to Twitter’s website disrupted service for many users late Thursday, directing them instead to a web page declaring “This site has been hacked by Iranian Cyber Army.” In the wake of the attack, which was fended off within hours, many fingers are … Continue reading “Report: Security Breach Behind Twitter Outage Did Not Originate with New Hampshire DNS Provider”

MediciNova Completes Merger

San Diego-based MediciNova, (NASDAQ: [[ticker:MNOV]]) which is developing small-molecule therapeutics through partnerships with Japanese pharmaceuticals, says it has merged Avigen, (NASDAQ: [[ticker:AVGN]]), a biotech based in Alameda, CA, that is focused on developing treatments for serious neurological disorders. Under the merger agreement, Avigen shareholders will receive either cash, secured convertible notes, or a combination of … Continue reading “MediciNova Completes Merger”

Oneforty Raises $1.2M More to Develop Twitter App Store

Oneforty, the Brighton, MA-based Twitter app store startup that has wooed and wowed angel investors on both coasts, has taken in about $1.25 million in new funding, to go along with $372,525 it had previously raised from debt financing that was converted to equity, according to an SEC filing today. The filing indicates the total … Continue reading “Oneforty Raises $1.2M More to Develop Twitter App Store”

TechStars in Seattle Will Be “Centralizing Force” for Entrepreneurs and Startups, Investors Say

Not to hype this too much, but TechStars coming to town could be the rallying point for a new generation of high-tech entrepreneurship in Seattle—the likes of which we haven’t seen before. At least, that’s the word from two of the main investors responsible for bringing the tech startup program here. (By now, most of … Continue reading “TechStars in Seattle Will Be “Centralizing Force” for Entrepreneurs and Startups, Investors Say”

Ambit Nabs Partnership With Astellas, $40M Upfront Cash, To Develop Leukemia Drug

Ambit Biosciences is showing that its third try to build a company looks like a charm. The San Diego-based biotech company said today it has secured a partnership with Japan-based Astellas Pharma to co-develop new drugs for cancer and other diseases. The deal revolves around Ambit’s lead experimental drug for acute myeloid leukemia, AC220, and … Continue reading “Ambit Nabs Partnership With Astellas, $40M Upfront Cash, To Develop Leukemia Drug”

Airvana Goes Private in $530M Deal

Chelmsford, MA-based Airvana (NASDAQ: [[ticker:AIRV]]), which makes femtocell equipment and other infrastructure for wireless operators, announced today that it’s departing the public markets and going private in a $530 million deal with a group of private-equity investors. Airvana will become a subsidiary of 72 Mobile Holdings, a new company owned by affiliates of S.A.C. Private … Continue reading “Airvana Goes Private in $530M Deal”

Chu Singles Out FloDesign’s Efficient Wind Turbines at Climate Change Conference

[Editor’s Note: Erik Mellgren, a noted Swedish business and technology journalist who worked with Xconomy as an Innovation Fellow in 2008, sends this article from Stockholm, just as the United Nations climate change conference is winding down in nearby Copenhagen, Denmark.] Massachusetts startup FloDesign Wind Turbine was singled out by U.S. Energy Secretary Steven Chu … Continue reading “Chu Singles Out FloDesign’s Efficient Wind Turbines at Climate Change Conference”

The Decade’s Most Important Biomedical Discovery

The past decade has been rich in biological and biomedical advances. The decade opened with the reports of the large number of new genes within the human genome that encode small non-coding RNAs, or microRNAs. We have learned that these RNAs a) control at least half of all genes, b) are dysfunctional in many cancers … Continue reading “The Decade’s Most Important Biomedical Discovery”

Apple Vs. Google, Genome Sequencing Goes Commercial, and More OVP Predictions for 2010

All this week, the venture capitalists over at OVP Venture Partners in Kirkland, WA, have been posting their thoughts on 2009—such as the biggest surprises in tech and life sciences—as well as their predictions for 2010. It’s a common theme these days, sure, but it’s always fun to get VCs on the record about such … Continue reading “Apple Vs. Google, Genome Sequencing Goes Commercial, and More OVP Predictions for 2010”

As Wireless Industry Moves From Voice to Data, Qualcomm’s Top Execs Discuss Their ‘Big Bets’ on Next-Generation Technologies

Qualcomm CEO Paul Jacobs seemed upbeat, at times even jocular, during a town hall forum at the wireless giant’s corporate headquarters Wednesday night. Perhaps his good humor stemmed from the kickoff question from moderator Brian Modoff, the Deutsche Bank Securities analyst, who asked Jacobs how he views Qualcomm now that the company has entered a … Continue reading “As Wireless Industry Moves From Voice to Data, Qualcomm’s Top Execs Discuss Their ‘Big Bets’ on Next-Generation Technologies”

Aveo Aims for $86M Debut, Exagrid Snags $16M, PatientKeeper Adds $13M, & More Boston-Area Deals News

In honor of the eighth day of Hanukah, here are the top eight deals of the last week. —Lexington, MA-based Cubist Pharmaceuticals (NASDAQ:[[ticker:CBST]]) inked a deal to acquire San Diego-based Calixa Therapeutics for $92.5 million upfront, with as much as $310 million more in potential payments also on the table. The merger of the firms, … Continue reading “Aveo Aims for $86M Debut, Exagrid Snags $16M, PatientKeeper Adds $13M, & More Boston-Area Deals News”