Gilead Drug For Cystic Fibrosis Fails to Win FDA Approval

Gilead Sciences suffered a big blow this afternoon, when it got word that its inhalable antibiotic for cystic fibrosis failed to win FDA approval. The Foster City, CA-based company, which has research and development offices in Seattle, said U.S. regulators are saying that another study must be done before aztreonam lysine can be cleared for … Continue reading “Gilead Drug For Cystic Fibrosis Fails to Win FDA Approval”

Puget Sound Business Journal Tackling Online News With Cook, Bishop

Fans of John Cook and Todd Bishop, never fear. The highly-regarded tech reporters who quit the Seattle Post-Intelligencer together yesterday will continue blogging like they have for years at the P-I, in a new role at the Puget Sound Business Journal. Today, the Business Journal said it is creating a new website featuring Cook’s coverage … Continue reading “Puget Sound Business Journal Tackling Online News With Cook, Bishop”

Cray, Microsoft Team Up to Sell $25K Windows Supercomputer—Will It Blue-Screen?

Remember when a supercomputer was an exotic, multimillion-dollar machine that took up a whole room and churned out calculations for quantum physics, molecular modeling, and other big science? Now, thanks to Moore’s Law and improvements in electronic design, your desktop PC is probably more powerful than what would have been called a “supercomputer” in 1990. … Continue reading “Cray, Microsoft Team Up to Sell $25K Windows Supercomputer—Will It Blue-Screen?”

Amgen’s Dmab Cuts Fracture Risk for Osteoporosis Patients, Just What Investors Wanted to See

Amgen finally has something emerging from its pipeline to thrill investors. The world’s largest biotech company, with research centers in Seattle and Cambridge, MA, is reporting today that its lead drug in development reduced the risk of spinal fractures for women with osteoporosis by a whopping 68 percent. On another dismal day in the markets, … Continue reading “Amgen’s Dmab Cuts Fracture Risk for Osteoporosis Patients, Just What Investors Wanted to See”

GE Shoots $4M Investment to Advanced Electron Beams

Advanced Electron Beams (AEB) of Wilmington, MA, has boosted its “green” credentials with technology that enables industry to sterilize or cure products without the energy costs and chemical waste of other solutions. General Electric (NYSE:[[ticker:GE]]) says it likes how AEB’s energy-efficient electron beam emitters complement GE’s “ecomagination” initiative to use more clean technologies, and now … Continue reading “GE Shoots $4M Investment to Advanced Electron Beams”

Daily TIPs: DNA for Doctors, Self-driving Prius, Google High on the Seas, & More

Berners-Lee Creates Web Foundation The man who invented the World Wide Web, Tim Berners-Lee, has launched a new foundation to promote open and expanded access to the Web. Ars Technica reports that the World Wide Web Foundation has $1 million in seed funding from the Knight Foundation. Specific goals of the project have not yet … Continue reading “Daily TIPs: DNA for Doctors, Self-driving Prius, Google High on the Seas, & More”

Ounce Labs Raises A Ton of New Funding

Waltham, MA-based Ounce Labs, whose software automatically scans the source code of enterprise applications for security flaws, said today that it has raised $7.5 million in Series D financing. A group led by Greylock Partners and Commonweath Capital Ventures, which both have offices in Waltham, contributed the funds, which will be used mainly to “accelerate … Continue reading “Ounce Labs Raises A Ton of New Funding”

Punchbowl Spiked With an Extra $2.1 Million

Punchbowl Software, the Framingham, MA, startup that runs the Web 2.0 party planning service MyPunchbowl (profiled here last October), has obtained its first major round of venture financing. The company raised $2.1 million from a group of investors including New York-based Contour Venture Partners and seed-round participants Intel Capital and eCoast Angels. MyPunchbowl is designed … Continue reading “Punchbowl Spiked With an Extra $2.1 Million”

Big Fish Gets Big Funds, UIEvolution Emerges, Targeted Growth Targets Biofuels, Healionics Dogs It, & More

As fall approaches, the Northwest deals (and other news) are starting to pick up. In the past week, we’ve seen plenty of action in mobile, gaming, biotech, and biofuels—including Washington state’s biggest venture deal of 2008 so far. —Seattle-based Big Fish Games has raised a whopping $83.3 million in Washington’s largest venture deal of the … Continue reading “Big Fish Gets Big Funds, UIEvolution Emerges, Targeted Growth Targets Biofuels, Healionics Dogs It, & More”

GI Dynamics’ Gut-Lining Device Combats Diabetes, Obesity in Small Trial

Patients battling obesity and Type 2 diabetes will sometimes go to great lengths to reduce the amount of food reaching their bloodstream, including having their gastrointestinal tracts rearranged in a procedure known as gastric bypass. But GI Dynamics may soon be able to offer a less drastic alternative—a two-foot-long flexible sleeve slipped into the GI … Continue reading “GI Dynamics’ Gut-Lining Device Combats Diabetes, Obesity in Small Trial”

Sirtris Gains SIRT3 Licenses from Harvard

Sirtris announced today that it has gained two exclusive licenses to Harvard University patents related to SIRT3, an enzyme believed to protect against cellular damage. The Cambridge, MA, biotech firm—which was acquired by British drug giant GlaxoSmithKline (NYSE: [[ticker:GSK]]) in June for $720 million—says the licenses cover assays that may identify SIRT3 activators for diseases … Continue reading “Sirtris Gains SIRT3 Licenses from Harvard”

Frazier Healthcare Hires Bob More of Domain Associates as General Partner

Frazier Healthcare Ventures, the Seattle-based venture firm, said today that Bob More has joined as a general partner in the firm’s California office. More worked the previous 12 years at Domain Associates, where he was involved with investments in ESP Pharma, Proxima Therapeutics, Onux Medical, and NovaCardia, all of which were acquired by larger companies. … Continue reading “Frazier Healthcare Hires Bob More of Domain Associates as General Partner”

Space Explorers Splash Down in Seattle, Try to Spark Childrens’ Imaginations

Space exploration doesn’t captivate the public imagination like it once did—and small wonder, considering that the Space Shuttle is limited to endless circles in low-earth orbit, a mere 250 miles up. So now the small group of people who have had the privilege of looking down on Earth are doing something about it. They are … Continue reading “Space Explorers Splash Down in Seattle, Try to Spark Childrens’ Imaginations”

Netezza Finds Its Way with Spatial Data

Marlborough, MA-based Netezza (NYSE: [[ticker:NZ]]) will today unveil a feature for which users of its data warehouse appliances have long been clamoring: location. The firm raised more than $100 million in a July 2007 IPO, based largely on the perceived strength of its appliances, which are designed to speed up the complex queries that business … Continue reading “Netezza Finds Its Way with Spatial Data”

Advanced Electron Beams Garners $4,000,000 New Funding Round

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=83e00e49-3f7d-4c98-8798-018e0aa325e9&Preview=1 Date 9/16/2008 Company Name Advanced Electron Beams Mailing Address 301 Ballardvale Street Wilmington, MA 01887 Company Description Advanced Electron Beams has developed one of the world’s most efficient and clean forms of industrial energy: the AEB Emitter. Conceived and developed by company founder Tovi Avnery, the AEB Emitter captures the power … Continue reading “Advanced Electron Beams Garners $4,000,000 New Funding Round”

Punchbowl Software, Inc. Obtains $2,100,000 Series A Round

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=8cd71157-bcdf-4791-8f6a-a9a9cf1d30a9&Preview=1 Date 9/16/2008 Company Name Punchbowl Software, Inc. Mailing Address 873 Concord Street Framingham, MA 01701 Company Description At Punchbowl Software, we believe that planning an event or party should be enjoyable and easy. Website http://www.mypunchbowl.com Transaction Type Venture Equity Transaction Amount $2,100,000 Transaction Round Series A Proceeds Purposes The new funding … Continue reading “Punchbowl Software, Inc. Obtains $2,100,000 Series A Round”

Ounce Labs Inc. Obtains $7,500,000 New Funding Round

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=52d3a1a2-e3c9-47c0-bd1c-e4100c116d72&Preview=1 Date 9/16/2008 Company Name Ounce Labs Inc. Mailing Address 100 Fifth Avenue Waltham, MA 02451 Company Description Ounce Labs delivers actionable metrics to help organizations understand and manage the vulnerabilities in their critical applications. Customers use this information to assess risk and prioritize security investments, to comply with regulatory demands, and … Continue reading “Ounce Labs Inc. Obtains $7,500,000 New Funding Round”

SolarReserve Obtains $140,000,000 Series B Funding

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=4c4db418-f1ff-4a87-842f-cb4fffe33cf2&Preview=1 Date 9/16/2008 Company Name SolarReserve Mailing Address 2425 Olympic Blvd. Santa Monica, CA 90404 Company Description SolarReserve was formed to solve two of the fundamental barriers of renewable energy: scalability and storage. Unlike hydroelectric, geothermal, biomass, and other renewable energy technologies that use limited renewable fuel sources, SolarReserve’s power plants draw … Continue reading “SolarReserve Obtains $140,000,000 Series B Funding”

VasoNova Obtains $10,000,000 Series B Funding

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=bb2ac099-5ef8-4ee4-ab72-30f002b7fe71&Preview=1 Date 9/16/2008 Company Name VasoNova Mailing Address 1368 Bordeaux Street Sunnyvale, CA 94089 Company Description The company operates as a medical device development company. Website http://www.vasonova.com Transaction Type Venture Equity Transaction Amount $10,000,000 Transaction Round Series B Proceeds Purposes Proceeds purposes were not disclosed. M&A Terms Venture Investor Aphelion Capital, LLC … Continue reading “VasoNova Obtains $10,000,000 Series B Funding”

ArKal Medical Obtains $17,500,000 Series B Funding

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=82aed883-61fc-4bdd-854c-3de4f04eee0f&Preview=1 Date 9/16/2008 Company Name ArKal Medical Mailing Address 46575 Fremont Blvd Fremont, CA 94538 Company Description ArKal Medical is developing a novel continuous glucose monitoring system for the management of diabetes. ArKal’s monitoring system is designed to eliminate many of the inconveniences of current glucose monitoring technologies. Website http://www.arkalmed.com Transaction Type … Continue reading “ArKal Medical Obtains $17,500,000 Series B Funding”

Foundog Lands Series A Financing Round

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=15d09222-5e8d-4534-9748-f420260b72e0&Preview=1 Date 9/16/2008 Company Name Foundog Mailing Address 21 Columbus Avenue 2nd Floor San Francisco, CA 94111 Company Description It happens to all of us-we leave our cell phone in the coffee shop, drop our MP3 or PDA on the subway, forget our camera in a restaurant. While those items are often … Continue reading “Foundog Lands Series A Financing Round”

Seattle P-I Tech Writers, Todd Bishop and John Cook, Bolt for Puget Sound Business Journal

The Puget Sound Business Journal got significantly stronger today. Two of Seattle’s best-known technology journalists, John Cook and Todd Bishop, have resigned from the Seattle Post-Intelligencer to take new jobs at the crosstown Business Journal. Cook, the author of the widely-read John Cook’s Venture Blog, joined the newspaper in April 1999. As he says in … Continue reading “Seattle P-I Tech Writers, Todd Bishop and John Cook, Bolt for Puget Sound Business Journal”

Seattle Versus San Francisco: Will There Be a Brain Drain to the Bay Area?

A couple weeks ago, we ran a story about the relationship between Seattle startups and San Francisco Bay Area VCs. We asked, what can Seattle entrepreneurs do to attract more attention from California investors? The responses I got from the tech-business community painted an interesting and complex picture of the local investment scene—but it was … Continue reading “Seattle Versus San Francisco: Will There Be a Brain Drain to the Bay Area?”

Mobile Monday Boston

The theme of this month’s student-oriented Mobile Monday Boston event is “Boston’s Most Successful Mobile Entrepreneurs.” On deck is a panel of founder-entrepreneurs including m-Qube founder and CTO Eswar Priyadarshan, Enpocket founder and CEO Jeremy Wright, and VoiceSignal founder and CEO Dan Roth, with moderator Shikhar Ghosh, founder and CEO of Appex and OpenMarket. Entrepreneurship-focused … Continue reading “Mobile Monday Boston”

.406 Invests in Ambient Devices

Boston’s .406 Ventures said today that it has “entered into an equity partnership” with Cambridge, MA-based Ambient Devices, known for its Ambient Orb, Ambient Umbrella, and other wireless displays designed to convey useful information at a glance. The two companies did not disclose the size of the investment (which is Ambient’s first from an institutional … Continue reading “.406 Invests in Ambient Devices”

GateRocket Blasts Off with $3 Million Series A Round

Bedford, MA-based GateRocket, which makes testing, verification, and debugging equipment for specialized microprocessors called field-programmable gate arrays or FPGAs, said today that it has closed a $3 million Series A financing round led by New Atlantic Ventures of Cambridge, MA and Reston, VA, the Massachusetts Technology Development Corporation (MTDC) of Boston, and Long River Ventures, … Continue reading “GateRocket Blasts Off with $3 Million Series A Round”

Skyhook, Centrix Collaborate on New Mac Software

Boston-based Skyhook Wireless and Winnipeg, Manitoba-based Centrix.ca announced today that Skyhook’s Wi-Fi Positioning System (WPS), which allows wireless devices to determine their geographic location based on the identities of nearby Wi-Fi networks, has been incorporated into the latest version of Centrix’s popular NetworkLocation software. The program automatically adjusts user settings on a Macintosh computer—for instance, … Continue reading “Skyhook, Centrix Collaborate on New Mac Software”

Daily TIPs: Broadband Bottleneck, Green Chemistry, Spammer Freed, & More

Most Countries Unready for Future Broadband Needs A group of MBA students has developed a Broadband Quality Score for 42 countries and found that the only country with enough bandwidth capacity to meet its needs in the next three to five years is Japan. Ars Technica reports that the score includes upload and download speeds … Continue reading “Daily TIPs: Broadband Bottleneck, Green Chemistry, Spammer Freed, & More”

Swedish Cleantech Venture Day

The Swedish-American Chambers of Commerce, New England, sponsors a full-day event featuring presentations by Swedish cleantech entrepreneurs seeking international venture funding, along with networking opportunities and educational sessions about the cleantech industry in Sweden. Keynote speakers include Swedish Ambassador and Consul General to New York Ulf Hjertonsson and Flagship Ventures general partner Jim Matheson. $300 … Continue reading “Swedish Cleantech Venture Day”

UIEvolution Raises $5M

Bellevue, WA-based UIEvolution, a maker of multimedia publishing software for mobile phones and other consumer electronics, announced that it has raised a Series A round led by Intel Capital, with Itochu also participating. The deal is reportedly worth some $5 million.

O Beverages Sips $6M More From Highland

Highland Capital Partners’ consumer fund led a $6 million Series D financing round for Cambridge, MA-based O Beverages, according to peHUB. Bob wrote about the fund’s earlier investment in the maker of nutrient-and flavor-infused waters (founded by Tom First of Nantucket Nectars fame), as well as the other firms in its consumer-oriented portfolio, back in … Continue reading “O Beverages Sips $6M More From Highland”

Enanta Pharmaceuticals Starts Clinical Trial of Antibiotic for Drug Resistant Bacteria

Enanta Pharmaceuticals, a Watertown, MA-based developer of anti-infection drugs, said today it has started an early stage clinical of an oral antibiotic for drug-resistant bacteria. The drug, EDP-322, is being tested for hospital and community-acquired infections, including drug-resistant MRSA. In previous animal tests, the drug showed activity against MRSA strains that resist other potent antibiotics … Continue reading “Enanta Pharmaceuticals Starts Clinical Trial of Antibiotic for Drug Resistant Bacteria”

Spark Capital Gains ‘Mo,’ as It Pushes Deeper Into NY Media and Entertainment Scene

Spark Capital today announced it has hired media and technology executive Moshe “Mo” Koyfman as a principal—making him a central part of the Boston-based venture firm’s deeper push into the New York (and national) media and entertainment technology space. With some $620 million under management through two funds, Spark focuses its investments on the intersection … Continue reading “Spark Capital Gains ‘Mo,’ as It Pushes Deeper Into NY Media and Entertainment Scene”

Proteostasis Eyes Technique to Keep Your Proteins in Balance

One of those foggy concepts from eighth-grade biology came back to me the other day when I spoke with David Pendergast. It’s homeostasis, the idea that the human body naturally makes constant adjustments on the fly to maintain a proper balance of things like body temperature, water, or salt in your system. Pendergast, the CEO … Continue reading “Proteostasis Eyes Technique to Keep Your Proteins in Balance”

IRobot Nabs Nekton Research, Carbonite Comes Up with $20M, Parametric Ponders $2 Billion, & More Deals News

It was a light week for dealmaking among New England tech and life sciences firms, but if Parametric finds a buyer that one could be a doozy. —Bedford, MA-based iRobot (NASDAQ: [[ticker:IRBT]]) inked an agreement to acquire Raleigh-Durham, NC-based Nekton Research—a maker of unmanned underwater robots—for $10 million up front and a potential $5 million … Continue reading “IRobot Nabs Nekton Research, Carbonite Comes Up with $20M, Parametric Ponders $2 Billion, & More Deals News”

Gilead’s Seattle Crew Awaits FDA Clearance of Cystic Fibrosis Drug, Catalyst for Future Growth

The people at Gilead Sciences in Seattle have been working toward this moment for seven years. Tomorrow is the FDA’s deadline to decide whether to approve aztreonam lysine, an inhalable antibiotic for cystic fibrosis. The drug was developed by Seattle-based Corus Pharma and led to its acquisition two years ago by Gilead for $365 million. … Continue reading “Gilead’s Seattle Crew Awaits FDA Clearance of Cystic Fibrosis Drug, Catalyst for Future Growth”

Verdasys Says it Has A Better Way to Protect Web Transactions Against Malware

It may sound strange, but there’s a computer security company just outside Boston where the engineers have declared that the conventional battle against viruses, worms, Trojan horses, and other forms of computer malware is already lost. Norton, McAfee, and other anti-virus companies may still make millions selling consumers software that promises to keep computers malware-free. … Continue reading “Verdasys Says it Has A Better Way to Protect Web Transactions Against Malware”

Gaterocket, Inc. Garners $3,000,000 Series A Round

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=a0f722e9-4e45-43e8-934e-388cbb99c4c9&Preview=1 Date 9/15/2008 Company Name Gaterocket, Inc. Mailing Address 19 Crosby Drive Bedford, MA 01730 Company Description GateRocket offers the industry’s first Device Native™ verification solution for Field Programmable Gate Arrays (FPGAs). This product can cut in half the time it takes to develop the electronic products that enrich our lives every … Continue reading “Gaterocket, Inc. Garners $3,000,000 Series A Round”

Ambient Devices Receives New Funding

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=c12d9dbc-1ae8-4103-ac66-4f2f7c3531a4&Preview=1 Date 9/15/2008 Company Name Ambient Devices Mailing Address One Broadway 14th Fl Cambridge, ME 02142 Company Description The company’s wireless technologies enable instant, effortless access to dynamic information, such as weather forecasts, stock market reports, sports scores, and much more — with little or no user configuration. Website http://www.ambientdevices.com Transaction Type … Continue reading “Ambient Devices Receives New Funding”

Soft Tissue Regeneration LLC Receives $3,500,000 Series A Funding

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=eeb0a856-6f99-4770-b0d0-52e75d4acec6&Preview=1 Date 9/15/2008 Company Name Soft Tissue Regeneration LLC Mailing Address 977 Seminole Trail Charlottesville, VT 22901 Company Description Soft Tissue Regeneration, LLC (“STR”) has developed and preliminarily tested a potential breakthrough technology for soft tissue regeneration of the anterior cruciate ligament (“ACL”) of the knee. Website http://www.softtissueregeneration.com Transaction Type Venture Equity … Continue reading “Soft Tissue Regeneration LLC Receives $3,500,000 Series A Funding”

Packet Design Secures $12,000,000 Series D Funding

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=47f64bce-ea72-4ce7-8884-233b83349e65&Preview=1 Date 9/15/2008 Company Name Packet Design Mailing Address 2455 Augustine Drive Santa Clara, CA 95054 Company Description Packet Design, Inc., develops and markets network solutions that leverage the distributed intelligence of the Internet Protocol (IP) to enhance the reliability, efficiency and predictability of IP networks. Website http://www.packetdesign.com Transaction Type Venture Equity … Continue reading “Packet Design Secures $12,000,000 Series D Funding”

Anagran Lands $8,600,000 Series D Round

Feed Type Link http://www.venturedeal.com/Search/SearchResultTransactionDetail.aspx?TransactionId=ea92f442-09d2-4b8c-8435-43a0b4a1783e&Preview=1 Date 9/15/2008 Company Name Anagran Mailing Address 580 North Pastoria Ave Sunnyvale, CA 94085 Company Description Anagran offers a variety of high-capacity flow management products designed to improve network performance, decrease costs, and allow integrated voice, video, and data applications to thrive over a single converged network. From the branch office … Continue reading “Anagran Lands $8,600,000 Series D Round”

Xconomy Rockin’ Tonight in Harvard Square

When we hired Greg Huang as our Seattle editor a few months ago, Rebecca wrote an article entitled, Introducing Greg. He Rocks. That’s because right after we hired him, he went on tour with what we described as his “fantastically quirky band,” Honest Bob and the Factory-to-Dealer Incentives. The band, which claims influences by the … Continue reading “Xconomy Rockin’ Tonight in Harvard Square”

Star Wars Inspires UW Scientist, Yoky Matsuoka, to Think Big About Making Artificial Hands

One of the scenes from The Empire Strikes Back gives you an idea of what Yoky Matsuoka is pursuing. It’s the part where Luke Skywalker tests out a prosthetic hand that he can control with all the dexterity of a natural one, well enough to wield one mean light saber. Matsuoka, a MacArthur “genius” award … Continue reading “Star Wars Inspires UW Scientist, Yoky Matsuoka, to Think Big About Making Artificial Hands”

Daily TIPs: Pot vs. MRSA, Wine vs. Heart Trouble, Podcars, & More

Marijuana Could Fight Resistant Staph Substances found in marijuana plants may provide a new weapon to fight drug-resistant bacteria, Technology Review reports. Scientists in England and Italy discovered antibacterial compounds in the plants and tested them against six strains of methicillin-resistant Staphylococcus aureus, or MRSA, which causes hard-to-treat skin infections that can be fatal in … Continue reading “Daily TIPs: Pot vs. MRSA, Wine vs. Heart Trouble, Podcars, & More”

Big Fish Lands $83.3 Million Investment Round

No sooner had Greg published his 45-company-long list of members of the Greater Seattle gaming cluster, than one of those companies—Big Fish Games—jumped out of the pool to grab the spotlight in a big (think $83.3 million) way. That was the whopping amount of new funding the Seattle company, founded in 2002 by Paul Thelen, … Continue reading “Big Fish Lands $83.3 Million Investment Round”

Givvy Launches Online Tools for Getting Organized About Your Charitable Giving

Back in February I tried a million different ways to get Givvy founder John Treadway to tell me exactly what is was his months-old startup was building. The best I could get out of him at the time was something about online tools that give individual donors “more control and more empowerment over why, when, … Continue reading “Givvy Launches Online Tools for Getting Organized About Your Charitable Giving”