A Need for Speed: Illumina Acquires San Diego’s Edico Genome

With the Bio-IT World Conference opening today in Boston, San Diego-based Illumina (NASDAQ: [[ticker:ILMN]]) said it has acquired Edico Genome, a five-year-old startup with  technology to accelerate the readout of next-generation sequencing data.

Illumina withheld terms of the deal in a statement released this morning. But an Illumina spokeswoman later confirmed that Illumina got Edico for $100 million, close to three times the estimated $32 million that Edico raised in venture funding from Qualcomm Ventures, Dell Technologies Capital, and individual investors.

Edico developed technology that combines a specialized processor and chipset with proprietary software to address a bottleneck in the process of reading the short DNA segments produced in genome sequencing, and aligning them with a reference genome. It’s a computationally intensive process referred to as genome “mapping” that Edico initially reduced from 20 hours to 20 minutes.

Last year, Edico adapted its technology for use with Amazon Web Services (AWS) and other cloud platforms, which dramatically increased its scalability (and available processing power) and made it possible to map a genome in near real time. Edico says its Dragen Bio-IT platform is available to run on a customer’s premises, in the cloud, or in a hybrid mode, and it is compatible for use with multiple data storage providers and analysis pipelines.

In recent years, AWS also has been significantly expanding its business in healthcare and life sciences. So while the Edico acquisition represents a good fit with Illumina’s technology, the deal also provides a possible added benefit of forestalling an AWS buyout of useful technology for processing genomic data.

In today’s statement, Susan Tousi, Illumina’s senior vice president of product development, says, “Our acquisition of Edico Genome is a big step toward realizing the vision of reducing sequencing data acquisition and analysis to a push-button, standardized process.”

In response to a query from Xconomy, an Illumina spokeswoman said Edico’s technology “complements Illumina’s sequencing portfolio, enabling customers to benefit from reduced investment in compute infrastructure and accelerated time to result, improving their overall efficiency and enabling greater emphasis on interpretation and reporting.”

Illumina’s statement also includes a call for the scientific community to adopt standards for genomics in health from Anthony Philippakis, chief data officer at the Broad Institute of MIT and Harvard. In a 2015 commentary for Xconomy, Edico founder and CEO Pieter van Rooyen issued a similar call to create shared standards for genomic data sequencing that would create a common framework for data analysis and interpretation.

“To me, this is just more evidence that the boundary between the life sciences and data science is blurring, and that you need to bring more resources to bear,” said Ashley Van Zeeland, the former CEO of Cypher Genomics (now part of Human Longevity Inc.), who is now working as an industry consultant.

In a research note this morning, analyst Puneet Souda of Leerink Partners wrote, “We see this as a positive and despite the competition in FPGAs (Field Programmable Gate Arrays), GPUs (Graphical Processing Units) and faster code—we see ILMN taking another step to ensure that data analysis does not hold back the progress of enormous data being generated by NovaSeq platforms around the world. The financial impact was already built into ILMN’s 2018 guide and ILMN gets 50 of Edico’s employees with the acquisition.”

Author: Bruce V. Bigelow

In Memoriam: Our dear friend Bruce V. Bigelow passed away on June 29, 2018. He was the editor of Xconomy San Diego from 2008 to 2018. Read more about his life and work here. Bruce Bigelow joined Xconomy from the business desk of the San Diego Union-Tribune. He was a member of the team of reporters who were awarded the 2006 Pulitzer Prize in National Reporting for uncovering bribes paid to San Diego Republican Rep. Randy “Duke” Cunningham in exchange for special legislation earmarks. He also shared a 2006 award for enterprise reporting from the Society of Business Editors and Writers for “In Harm’s Way,” an article about the extraordinary casualty rate among employees working in Iraq for San Diego’s Titan Corp. He has written extensively about the 2002 corporate accounting scandal at software goliath Peregrine Systems. He also was a Gerald Loeb Award finalist and National Headline Award winner for “The Toymaker,” a 14-part chronicle of a San Diego start-up company. He takes special satisfaction, though, that the series was included in the library for nonfiction narrative journalism at the Nieman Foundation for Journalism at Harvard University. Bigelow graduated from U.C. Berkeley in 1977 with a degree in English Literature and from the Columbia University Graduate School of Journalism in 1979. Before joining the Union-Tribune in 1990, he worked for the Associated Press in Los Angeles and The Kansas City Times.